Effects of quinestrol on hepatic function in the rat.

Abstract:

:Hepatic function in female rats given 200 microgram of quinestrol every 15 days for up to 210 days was studied. Prolonged treatment with quinestrol affected liver weight, serum cholestrol levels, biliar flux, and bromosulphthalein test, but these parameters tended toward control levels after 30 days of treatment. Quinestrol failed to affect alkaline phosphatase, oxalacetic and pyruvic transaminases and the concentration of bilirubin in serum and bile. The effects of quinestrol on hepatic function are similar to the effects of other estrogen derivatives.

journal_name

Contraception

journal_title

Contraception

authors

Gioia IA,Lencioni LJ,Koch OR

doi

10.1016/s0010-7824(78)80021-3

subject

Has Abstract

pub_date

1978-09-01 00:00:00

pages

277-86

issue

3

eissn

0010-7824

issn

1879-0518

pii

S0010-7824(78)80021-3

journal_volume

18

pub_type

杂志文章
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    abstract::There is considerable variation in opinion about the importance of drug interactions between the combined oral contraceptive pill (COCP) and broad-spectrum antibiotics. Clinical practice varies widely, especially between doctors in Europe and those in the US. Rifampicin and griseofulvin induce hepatic enzymes and do a...

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    pub_type: 杂志文章,评审

    doi:10.1016/s0010-7824(99)00009-8

    authors: Weaver K,Glasier A

    更新日期:1999-02-01 00:00:00

  • Cervical carcinoma in situ and use of depot-medroxyprogesterone acetate (DMPA). WHO Collaborative Study of Neoplasia and Steroid Contraceptives.

    abstract::The relationship of depot-medroxyprogesterone acetate (D-MPA) use to risk of cervical carcinoma in situ was investigated using data from a large multi-national, hospital-based case-control study. To avoid possible detection bias from Pap smear screening, final analyses were restricted to a subset of cases with symptom...

    journal_title:Contraception

    pub_type: 杂志文章,多中心研究

    doi:10.1016/0010-7824(94)00007-j

    authors: Thomas DB,Ye Z,Ray RM

    更新日期:1995-01-01 00:00:00

  • Doxycycline serum levels at the time of dilation and evacuation with two dosing regimens.

    abstract:BACKGROUND:Doxycycline is commonly used for antibiotic prophylaxis before dilation and evacuation (D&E) but frequently causes nausea and emesis which may affect absorption and effectiveness. Taking doxycycline the night prior to surgery may result in adequate absorption with better tolerance. STUDY DESIGN:We enrolled ...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2008.09.006

    authors: Reeves MF,Lohr PA,Hayes JL,Harwood BJ,Creinin MD

    更新日期:2009-02-01 00:00:00

  • Fertility following discontinuation of different methods of fertility control.

    abstract::The possibility of permanent sterility following use of modern contraceptive agents is a concept which causes great concern amongst members of the lay public. However, a thorough review of the literature gives a great deal of reassurance on this topic. The combined oral contraceptive pill causes slight delay, and the ...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/0010-7824(82)90105-6

    authors: Fraser IS,Weisberg E

    更新日期:1982-10-01 00:00:00

  • Postovulatory contraception in women with large doses of norethindrone.

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    pub_type: 杂志文章

    doi:10.1016/0010-7824(72)90011-x

    authors: Nygren KG,Johansson ED,Wide L

    更新日期:1972-06-01 00:00:00

  • The influence of hormonal contraceptives on sex hormone binding globulin (SHBG) capacity.

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    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(75)90050-5

    authors: van Kammen E,Thijssen JH,Rademaker B,Schwarz F

    更新日期:1975-01-01 00:00:00

  • Gestational dating using last menstrual period and bimanual exam for medication abortion in pharmacies and health centers in Nepal.

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    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2018.06.004

    authors: Averbach S,Puri M,Blum M,Rocca C

    更新日期:2018-10-01 00:00:00

  • Efficacy and side effects of immediate postcoital levonorgestrel used repeatedly for contraception. United Nations Development Programme/ United Nations Population Fund/World Health Organization/World Bank Special Programme of Research, Development and Re

    abstract::We evaluated the efficacy and side effects of immediate postcoital administration of levonorgestrel 0.75 mg used repeatedly for contraception. A total of 295 healthy women with infrequent coitus were enrolled at 6 study sites. Each woman took levonorgestrel 0.75 mg by mouth immediately after intercourse during 6 month...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:2000-05-01 00:00:00

  • Ultrastructural changes in the spermatozoa of langur monkeys Presbytis entellus entellus after vas occlusion with styrene maleic anhydride.

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    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(98)00011-0

    authors: Lohiya NK,Manivannan B,Mishra PK

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  • Pharmacokinetic study of orally administered RU 486 in non-pregnant women.

    abstract::A method based on HPLC was devised for the estimation of RU 486 in blood and utilised to study the pharmacokinetics of a single dose of 50 mg RU 486 administered orally to 12 women on day 7 of the cycle. The dose was rapidly absorbed with peak plasma concentration between 1 and 2 hours. Distribution was also rapid (me...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(89)90052-8

    authors: He CH,Shi YE,Ye ZH,Zhang GG,Jiang NX,Van Look PF,Fotherby K

    更新日期:1989-10-01 00:00:00

  • Safety of hormonal contraception and intrauterine devices among women with depressive and bipolar disorders: a systematic review.

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    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2016.06.012

    authors: Pagano HP,Zapata LB,Berry-Bibee EN,Nanda K,Curtis KM

    更新日期:2016-12-01 00:00:00

  • A comparison of three daily coital diary designs and a phone-in regimen.

    abstract::Barrier contraceptive trials and disease intervention studies often utilize coital diaries to measure sexual exposures: dates and frequency of intercourse, product use, additional or alternative contraceptive use, and menstrual bleeding. The validity of these self-reported data is a matter of debate, but if used, bett...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0010-7824(01)00183-4

    authors: Hays MA,Irsula B,McMullen SL,Feldblum PJ

    更新日期:2001-03-01 00:00:00

  • Two-year follow-up of changes in clinical chemistry in Singaporean Norplant-2 rod acceptors: haemostatic changes.

    abstract::A longitudinal study of coagulation parameters was carried out on 100 Singaporean acceptors using Norplant-2 rods for contraceptive purposes. At the end of 2 years of use, results from this study show a return of platelet count to preinsertion level while platelet aggregation remained significantly enhanced. Thus the ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(89)80004-6

    authors: Singh K,Viegas OA,Koh S,Singh P,Ratnam SS

    更新日期:1989-02-01 00:00:00

  • Abortion referral-making in the United States: findings and recommendations from the abortion referrals learning community.

    abstract::In recent years, reproductive health researchers and practitioners have increased their focus on abortion referrals as an overlooked component of access. March 2019 proposed changes to the regulation of publicly funded family planning services that severely restrict abortion referrals have heightened public attention....

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2019.07.141

    authors: Zurek M,O'Donnell J

    更新日期:2019-11-01 00:00:00

  • Domestic violence against women seeking induced abortion in China.

    abstract::A cross-sectional study was conducted to investigate the prevalence, type and severity of domestic violence (DV), and determine the factors related to DV among women seeking induced abortion in China. A total of 1215 women seeking induced abortion were interviewed. The results show that the prevalence of DV among part...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2005.02.010

    authors: Wu J,Guo S,Qu C

    更新日期:2005-08-01 00:00:00

  • Pharmacokinetic study of RU 486 and its metabolites after oral administration of single doses to pregnant and non-pregnant women.

    abstract::RU 486 and three of its metabolites (RU 42633-monodemethyl, RU 42848-didemethyl, and RU 42698-hydroxymetabolite) were determined by HPLC in plasma from nine non-pregnant and 36 pregnant women. Each non-pregnant subject took an oral dose of RU 486 (25, 100, 400 and 600 mg consecutively) once per menstrual cycle. Six of...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(93)90004-q

    authors: Shi YE,Ye ZH,He CH,Zhang GQ,Xu JQ,Van Look PF,Fotherby K

    更新日期:1993-08-01 00:00:00

  • Effect of BMI and body weight on pregnancy rates with LNG as emergency contraception: analysis of four WHO HRP studies.

    abstract:OBJECTIVE:To estimate the effect of increased body weight and body mass index (BMI) on pregnancy rates with levonorgestrel (LNG) 1.5mg used as emergency contraception (EC). METHODS:The study reviewed data from 6873 women in four WHO-HRP randomized trials on EC conducted between 1993 and 2010. Participants took either ...

    journal_title:Contraception

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.contraception.2016.08.001

    authors: Festin MPR,Peregoudov A,Seuc A,Kiarie J,Temmerman M

    更新日期:2017-01-01 00:00:00

  • A comparative study of Neo Sampoon, Ortho Vaginal Tablets and Emko Vaginal Tablets in Accra, Ghana.

    abstract::Neo Sampoon is an effervescent contraceptive vaginal tablet manufactured in Japan that contains 60 mg of the spermicide menfegol. Ortho Vaginal Tablets (OVT) and Emko Vaginal Tablets (EVT), both containing 100 mg of the spermicide nonoxynol-9, were manufactured in the USA. The three products were compared in a randomi...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(85)90015-0

    authors: Lamptey P,Klufio C,Smith SC,Feldblum PJ

    更新日期:1985-11-01 00:00:00

  • Termination of early pregnancy (menstrual induction) with 16-phenoxy-omega-tetranor PGE2 methylsulfonylamide.

    abstract::The efficacy and side effects of a new synthetic compound, 16-phenoxy-W-17, 18, 19, 20-tetranor prostaglandin E2 methylsulfonylamide, for menstrual induction. The study was conducted in an outpatient clinic in 240 patients with a delay in menstruation of 6-14 days. In 206 patients (86%) the immunologic pregnancy tes...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(77)90049-x

    authors: Karim SM,Rao B,Ratnam SS,Prasad RN,Wong YM,Ilancheran A

    更新日期:1977-10-01 00:00:00

  • Irregular bleeding, body mass index and coital frequency in Norplant contraceptive users.

    abstract::Seventy-five women with a mean age of 27.5 years who requested Norplant implants for contraception were studied over a five-year period. The patients kept daily diaries of their vaginal bleeding and coital frequency, and were seen at least every six months at which time their weight was measured. This study examines t...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章

    doi:10.1016/0010-7824(94)90047-7

    authors: Pasquale SA,Knuppel RA,Owens AG,Bachmann GA

    更新日期:1994-08-01 00:00:00

  • Effect of steroid hormones on the metabolism of human spermatozoa.

    abstract::Information relating to the effect of steroids on the metabolism and motility of human spermatozoa is limited despite the increasing interest in the use of these hormones for the purpose of contraception. In the present study it was shown that progesterone, testosterone, and 11-beta-OH-progesterone significantly inhib...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(81)90080-9

    authors: Trifunac NP,Bernstein GS

    更新日期:1981-05-01 00:00:00

  • Developing future leaders in reproductive health through a scholarly concentration for medical students.

    abstract:OBJECTIVES:To evaluate the impact of a scholarly concentration for medical students, which aims to develop students' research, clinical and advocacy skills to promote women's reproductive health. STUDY DESIGN:Scholarly concentration programs provide opportunities to engage in scholarship beyond the traditional medical...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2014.07.005

    authors: Nothnagle M,Radlinski H,Magee SR,Allen RH

    更新日期:2014-11-01 00:00:00

  • Contraceptive knowledge and use among low-income Hispanic immigrant women and non-Hispanic women.

    abstract:BACKGROUND:With the rising influx of Hispanics to the United States, there is an ongoing need to promote health and wellness care to this non-English-speaking, minority population group. Programs, specifically developed to address the unique cultural mores of Hispanics, need to focus on increasing knowledge about healt...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2007.12.008

    authors: Garcés-Palacio IC,Altarac M,Scarinci IC

    更新日期:2008-04-01 00:00:00

  • The effect of nitroglycerin on the IUD insertion experience in nulliparous women: a pilot study.

    abstract:OBJECTIVE:Concern about pain during placement of an intrauterine device (IUD) represents a barrier to use, especially among nulliparous women. We hypothesized that nitroglycerin gel applied vaginally 30 min prior to IUD placement would reduce insertion-related pain. STUDY DESIGN:We designed a randomized, double-blinde...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2014.03.012

    authors: Micks EA,Jensen JT,Bednarek PH

    更新日期:2014-07-01 00:00:00

  • Interest in and experience with IUD self-removal.

    abstract:OBJECTIVES:In the United States, the popularity of intrauterine devices (IUDs) is low despite many positive attributes such as high effectiveness and ease of use. The requirement that a clinician remove the IUD may limit US women's interest in the method. Our objective was to describe women's experience with self-remov...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2014.01.025

    authors: Foster DG,Grossman D,Turok DK,Peipert JF,Prine L,Schreiber CA,Jackson AV,Barar RE,Schwarz EB

    更新日期:2014-07-01 00:00:00

  • Sperm-specific ion channels: targets holding the most potential for male contraceptives in development.

    abstract::There is a global need for an ideal method of male contraception. However, the development of male contraceptives has not been well successful. Research on sperm-specific ion channels, especially the recent advance obtained from electrophysiological studies, has emphasized the conception that those channels are target...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2013.06.002

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    更新日期:2013-10-01 00:00:00

  • Effect of cupric ions on the incorporation of 3H-thymidine and 5-3H-uridine into nucleic acids of rabbit endometrial cells. An in vitro study.

    abstract::The effect of cupric ions on the uptake of tritiated-thymidine and 5-tritiated-uridine into endometrial cells obtained from pseudopregnant rabbits was studied in vitro. In endometrial cells obtained 48 and 120 hours after human chorionic gonadotropin injection, the uptake of tritiated-thymidine was significantly inhi...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(75)90076-1

    authors: Grundsell H,Håkansson L

    更新日期:1975-10-01 00:00:00

  • In vivo measurements of uterine cavities in 795 women of fertile age.

    abstract::The uterine sound length, the functional length of the cervix including the zone of internal cervical os and the fundus transversal were determined in 795 fertile women in vivo using a measuring device, the Cavimeter. The functional cavity length was calculated by subtracting the functional length of the cervix from t...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(84)80011-6

    authors: Kurz KH,Tadesse E,Haspels AA

    更新日期:1984-06-01 00:00:00

  • Interval iud insertion in parous women: a randomized multicentre comparative trial of the Lippes Loop D, TCu220c and the Copper 7.

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    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(82)90167-6

    authors:

    更新日期:1982-07-01 00:00:00

  • Task-shifting the provision of DMPA-SC in the DR Congo: Perspectives from two different groups of providers.

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    doi:10.1016/j.contraception.2018.07.002

    authors: Hernandez JH,Akilimali P,Glover A,Emel R,Mwembo A,Bertrand J

    更新日期:2018-11-01 00:00:00