Abstract：
:Early alterations in the epidermis of human volunteers following 60 degrees and 95 degrees C burns were studied by means of electron microscopy. The blister was induced at 30 seconds following a 60 degrees C burn for 1 and 3 minutes by disintegration of the basal cells just above the basement membrane, and, in addition, for 3 minutes by disruption of the intercellular bridges adjacent to the desmosomes in the suprabasal cells. The keratinocytes of the separated epidermis revealed intracytoplasmic vacuoles, widening of the intercellular spaces and, in some cells, vacuolization of the mitochondria. At 30 seconds following a 95 degrees C burn for 3 seconds, the blister was induced by complete breakage of the basal and suprabasal cells which demonstrated karyorrhexis, aggregated tonofibrils and breaks in the plasma membrane. The keratinocytes of the blister roof showed aggregation of the tonofibrils at the periphery, and vacuolization of mitochondria and endoplasmic reticulum. The desmosomes and basement membrane revealed no alterations with 60 degrees and 95 degrees C burns.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Takigawa M,Ofuji Ssubject
Has Abstractpub_date
1977-01-01 00:00:00pages
187-93issue
3eissn
0001-5555issn
1651-2057journal_volume
57pub_type
杂志文章abstract：:The combination of hydroxyzine and cimetidine is reported to be more effective than hydroxyzine alone in chronic urticaria. The plasma concentration of hydroxyzine was studied in seven patients treated both with the hydroxyzine 25 mg t.i.d. and the combinations of hydroxyzine 25 mg and cimetidine 200 mg t.i.d. Hydroxy...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:The expression of the transglutaminase I in human anagen hair follicles was studied by an immunohistochemical staining. In the bulbar and suprabulbar portions of anagen hair follicles, transglutaminase I was detected on the hair cuticle and the three layers of the inner root sheath. Subsequently, the positive staining...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555575190192
更新日期：1995-05-01 00:00:00
abstract：:The anti-inflammatory mechanisms of minocycline, an antibiotic used in the treatment of the inflammatory component of acne, are only partially understood. In addition to inflammation due to cytokines (IL-1, IL-6, TNF-alpha, etc.), recent studies have shown that neuropeptide-mediated neurogenic inflammation may play an...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155599750010625
更新日期：1999-07-01 00:00:00
abstract：:The aim of this study was to determine the prevalence and type of cutaneous manifestations which occur in patients with granulomatosis with polyangiitis and to explore the potential association between cutaneous and systemic involvement in these patients. A retrospective case series study was designed, including all g...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3506
更新日期：2020-05-28 00:00:00
abstract：:The hairless mouse has been used as a model to distinguish between local and systemic atrophogenic effects of topical steroids. Hydrocortisone-17-butyrate, betamethasone-17-valerate, budesonide and clobetasol-17-propionate were applied topically daily for 21 days. Skinfold thickness and dermal DNA synthesis of treated...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Studies on hydroxyproline and hydroxylysine, the two amino acids characteristic of collagen and related glycoproteins, were undertaken on biopsies of pathologic and clinically normal human skin. No statistically significant differences between clinically normal skin of mamma, thorax, axilla, femur, hip and sacral area...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Although palmoplantar psoriasis can be severely disabling, there are very few large clinico-epidemiological studies on this condition. Our purpose was to study the morphology and pattern of lesions in Indian patients with palmoplantar psoriasis and to elucidate the role of occupation in the incidence/localization of t...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/00015550260132488
更新日期：2002-01-01 00:00:00
abstract：:The expression of blood-group antigens was studied on human epidermal cultures used as allografts in 13 non-immunosuppressed patients treated for leg ulcers. The study was carried out using monoclonal antibodies to A and B antigens by an indirect immunofluorescence technique. Blood-group antigens are weakly expressed ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Repeated topical analgesia with EMLA 5% cream prior to the cleansing of venous leg ulcers was studied. Patients were randomly allocated to a series of 8 treatments with EMLA (n = 22) or to a control group (n = 21). A thick layer of the cream was applied to the ulcers for 30 min. At each of the 8 treatments, local reac...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2340/000155555573231233
更新日期：1993-06-01 00:00:00
abstract：:Conflicting results regarding the association of a polymorphism at codon 72 of the p53 tumour suppressor gene and susceptibility to develop human papilloma virus (HPV)-associated cervical cancer have been published over the last year, implicating differences in ethnic background, sample origin, sample size and/or dete...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/00015550152384272
更新日期：2001-05-01 00:00:00
abstract：:While temperatures in the noxious range are well-known to inhibit acute itch, the impact of temperature in the innocuous temperature range is less well understood. We investigated the effect of alternating short-term temperature changes in the innocuous range on histamine and cowhage-induced acute itch, taking into ac...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3077
更新日期：2019-02-01 00:00:00
abstract：:Disutility reflects the disability caused by a disease. The EuroQoL-5D (EQ-5D) questionnaire is a measure of health-related overall utility. The questionnaire has only been applied previously to a small number of patients with hidradenitis. In this study a survey of 421 patients with hidradenitis suppurativa was condu...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-2129
更新日期：2016-02-01 00:00:00
abstract：:The effect of occlusion on epidermal morphology was studied at electron microscopic resolution. the morphological changes recorded were relatively mild, though conspicuous, and consisted in dilatation of the intercellular space, appearance of cytoplasmic vacuoles and an oedematous change in the dermis. Stereological a...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Homogenates of irradiated and non-irradiated skin from 16 patients with chronic polymorphous light eruptions (CPLE) were examined to detect possible light-induced antigen to cell-mediated immunity. The leukocyte migration agarose tests which were performed disclosed no evidence of migration inhibition in either type o...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:The main aims of this cross-sectional study were: (i) to assess the frequency of genital (vulval) lichen planus (VLP) and vulval lichen sclerosus (VLS) in women affected with oral lichen planus (OLP), regardless of the genital symptoms reported; and (ii) to verify whether any demographic, clinical, or histological fea...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0116
更新日期：2006-01-01 00:00:00
abstract：:Scalp psoriasis is associated with hair loss and an increased telogen/anagen ratio. Topical treatment of scalp psoriasis (with corticosteroids, dithranol or tar) results in decreased scaling, induration and erythema of the plaques. Calcipotriol is effective in the treatment of psoriasis vulgaris. However, the potent g...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,多中心研究
doi：10.2340/0001555575388390
更新日期：1995-09-01 00:00:00
abstract：:Hypopigmented macules are frequently observed in the photodamaged skin of elderly people. We undertook to study and treat 2 types of hypomelanosis of photoaged skin. These lesions were: 1) idiopathic guttate hypomelanosis; and 2) macular hypomelanosis. Comparative studies included: 1) high-resolution photography using...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155599750010724
更新日期：1999-07-01 00:00:00
abstract：:Psoriasin, which is highly expressed in psoriasis, is encoded by a gene located within the epidermal differentiation complex. The aim of this study was to investigate the effect of endogenous psoriasin on disturbed keratinocyte differentiation in psoriasis. Immunohistochemical staining revealed a gradient of psoriasin...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-2596
更新日期：2017-04-06 00:00:00
abstract：:In a randomized, controlled parallel group study we have shown that cyclosporine at 3 mg/kg/day is as effective as topical betamethasone-17,21-dipropionate in the treatment of chronic hand eczema. In this study we compared the influence of these therapies on the quality of life. Forty-one patients were treated with ei...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2340/00015555775458
更新日期：1997-01-01 00:00:00
abstract：:Loricrin, the major component of the cornified envelope, is normally expressed in the granular layer of epidermis during the last steps of keratinocyte differentiation. Using an antiloricrin antiserum (A8-73), an increased expression of this envelope precursor was found in some disorders of hyperorthokeratosis (ichthy...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：102340/0001555572407409
更新日期：1992-11-01 00:00:00
abstract：:A 31-year-old woman developed typical clinical and laboratory signs of PCT at the end of her second pregnancy coincident with the summer season. She had elevated liver function values without history of alcoholism, hepatitis or chemical liver damage. She had taken oral contraceptive only before her first pregnancy whi...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Patients with clinical features of dorsal macular amyloidosis but without subepidermal amyloid deposits were followed for 2-11 years. The clinical appearance was fairly stable during this period of time, with little tendency of healing. Only 2 of the patients developed typical macular amyloidosis during the follow-up....
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555576302304
更新日期：1996-07-01 00:00:00
abstract：:One of the prepolymers used in Ultraviolet (UV) curing ink formulations is acrylated polyester. The prepolymer investigated is a dimethacrylated polyester, thus a saturated polyester terminated with methacrylic groups. In conventional UV-curing coatings the prepolymer commonly used is an unsaturated polyester. Three o...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Having observed altered itch and flare reactions after histamine application in patients with atopic eczema, we tried to determine these reactions in patients with urticaria and psoriasis. We investigated 16 healthy non-atopic subjects, 16 atopics in an eczema-free interval, 16 with acute atopic eczema, 16 with urtica...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155598433458
更新日期：1998-03-01 00:00:00
abstract：:Eight out of 30 consecutive patients with AIDS and cryptococcal meningoencephalitis (26,7%) presented cutaneous involvement, in the form of papulo-nodular lesions in 3 patients, molluscum contagiosum-like lesions in 3 patients, and pustular-ulcerative lesions in 2 patients. Skin localization represented an untoward pr...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555767274
更新日期：1996-01-01 00:00:00
abstract：:In order to study the flare-up of contact allergy, 35 patients with a contact allergy to gold were given an intramuscular injection of 10 mg gold sodium thiomalate, i.e. the anti-rheumatic drug Myocrisin. Clinical reactions comprised an eczematous flare-up of previously positive patch tests to gold and of a previous d...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：:The skin reactions to skin provocation tests with 11 primary irritants were compared in 21 pairs of men and women with hand eczema, matched for age, and in 21 pairs of non-eczematous subjects. With a few exceptions, no statistically significant differences were demonstrated in the intensities of the skin reactions bet...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：102340/0001555555191194
更新日期：1975-01-01 00:00:00
abstract：:In a patient affected with acrodermatitis continua Hallopeau, acitretin (Ro 10-1670) monotherapy resulted in a complete clearance of pustulation at a dosage of 45 mg per day. At this dosage the leukotriene B4-induced intraepidermal accumulation of polymorphonuclear leukocytes was markedly inhibited. ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Urinary excretion of glycosaminoglycans was measured in 10 patients with pretibial myxoedema, 7 of whom also had thyroid-associated ophthalmopathy, and in 3 additional patients with ophthalmopathy but no skin changes. Total uronic acid excretion was raised above control levels in only 2 patients, who had both eye and ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555576368370
更新日期：1996-09-01 00:00:00
abstract：:We set out to show that the assumption is incorrect that continuous treatment with cyclosporin is necessary in psoriasis, as this tenet forms a basis for current recommended treatment regimens. Sixty patients with mild to moderate plaque psoriasis were allocated at random to treatment with oral cyclosporin 5 mg/kg/day...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2340/00015555756569
更新日期：1995-01-01 00:00:00
