Abstract:
:Abnormal creatine kinase (CK) isoenzyme patterns were observed in the serum of a 64-year-old woman with severe heart disease. Agarose electrophoresis revealed the presence of all the usual CK isoenzymes (MM, MB, and BB) plus an extra band between MM and MB. Total serum CK activity was within the normal range. Within 2 h after the patient suffered cardiorespiratory arrest, a fifth CK isoenzyme appeared, cathodal to MM. After cardiac valve replacement, the patient's serum showed a high activity of CK, but the isoenzyme pattern showed only MM and, transiently, an MB band. With return of the serum CK activity to normal, the CK isoenzymes pattern also became normal, virtually ruling out genetic variant(s). The abnormal CK isoenzyme patterns might have been the consequence of severe hypoxemia in the patient, thus such patients may represent an ominous prognostic sign. The association of the abnormal pattern upon admission with rapid deterioration of the condition of the patient suggests prompt attention for the prevention of complications.
journal_name
Clin Chemjournal_title
Clinical chemistryauthors
Csako G,Papadopoulos NM,Jett GK,McIntosh CLsubject
Has Abstractpub_date
1982-10-01 00:00:00pages
2170-2issue
10eissn
0009-9147issn
1530-8561journal_volume
28pub_type
杂志文章abstract::Energy-dispersive x-ray spectroscopy and inductively coupled plasma emission spectrometry were evaluated as methods for routine multielement analysis of biological material. Standard samples included Standard Reference Materials (National Bureau of Standards), compounded mixtures, and supplements that provided a wide ...
journal_title:Clinical chemistry
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doi:
更新日期:1976-12-01 00:00:00
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journal_title:Clinical chemistry
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journal_title:Clinical chemistry
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更新日期:1981-02-01 00:00:00
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doi:
更新日期:1988-04-01 00:00:00
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journal_title:Clinical chemistry
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
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journal_title:Clinical chemistry
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
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journal_title:Clinical chemistry
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:
更新日期:1998-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-02-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
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更新日期:2010-02-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
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doi:
更新日期:1989-06-01 00:00:00
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doi:10.1373/clinchem.2006.066720
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更新日期:1987-06-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
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journal_title:Clinical chemistry
pub_type: 杂志文章
doi:
更新日期:1982-04-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
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更新日期:1999-12-01 00:00:00
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更新日期:1991-08-01 00:00:00
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journal_title:Clinical chemistry
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:1977-06-01 00:00:00
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