Abstract:
:We conducted a histopathologic study of he meibomian glands of seven patients (all men, ranging in age from 58 to 83 years) who had severe or moderately severe meibomian dysfunction and who were undergoing ectropion or entropion repair. Abnormal features included signs of obstruction and dilatation of ducts, enlargement of acini with cystic degeneration and squamous metaplasia, foreign-body reaction and granuloma formation, a mild increase in inflammatory cells, and abnormal keratinization. Demodex organisms were found in both acini and ducts of one patient. These findings were similar to those reported in other entities involving meibomian duct obstruction, probably related to abnormalities of keratinization, plays an important role in the pathogenesis of meibomian gland dysfunction.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Gutgesell VJ,Stern GA,Hood CIdoi
10.1016/0002-9394(82)90365-8subject
Has Abstractpub_date
1982-09-01 00:00:00pages
383-7issue
3eissn
0002-9394issn
1879-1891pii
0002-9394(82)90365-8journal_volume
94pub_type
杂志文章abstract:PURPOSE:To compare immunocytochemical and ultrastructural characteristics of "lamellar hole-associated epiretinal proliferation" in lamellar macular holes with "conventional epiretinal membrane" in macular pseudoholes. DESIGN:A consecutive observational case series, laboratory investigation. METHODS:We analyzed surgi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.05.010
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To evaluate the effect on peripheral visual field defects occurring after macular hole surgery of passing air that is used for fluid-air exchange through water before infusion to the eye. METHODS:We used Goldmann perimetry to measure the visual fields of patients who underwent vitrectomy to manage idiopathic f...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00287-6
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To determine the etiologies and management of calcific band keratopathy (CBK), and assess the results and long-term follow-up after ethylenediamine-tetraacetic acid (EDTA) chelation. DESIGN:Retrospective interventional case series. METHODS:Two hundred thirty patients with clinically significant CBK were inclu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.01.036
更新日期:2004-06-01 00:00:00
abstract:PURPOSE:To study the effect of higher-order aberrations (HOAs) on visual function in keratoconus with a rigid gas permeable (RGP) contact lens (CLs). DESIGN:Retrospective nonrandomized study. METHODS:Thirteen eyes of 10 subjects with keratoconus who wore a RGP CLs (KC-RGP group), 15 eyes of nine normal subjects (norm...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.08.004
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To determine the frequency of retinal thickening (RT) in eyes with iridocyclitis and to examine the correlations among anterior chamber (AC) inflammation, RT, and visual acuity. DESIGN:Retrospective, observational case series. METHODS:Records were reviewed of patients seen at the Duke University Eye Center Uv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.03.034
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To describe the clinical and histopathologic findings in a patient with Parinaud's oculoglandular syndrome attributable to Francisella tularensis obtained from an encounter with a wild baby rabbit. METHODS:In an 18-year-old man, the clinical course, laboratory findings, and histopathologic findings are describ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00954-5
更新日期:2001-02-01 00:00:00
abstract:PURPOSE:To learn whether electrophysiological changes indicating amblyopia occur even in the absence of clinically recognizable amblyopia. DESIGN:Prospective study. METHODS:Four consecutive infants between 7 and 19 months of age with unilateral periocular vascular lesions that intermittently obstructed vision in the ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.11.007
更新日期:2009-04-01 00:00:00
abstract:PURPOSE:Distance stereoacuity is used to monitor deterioration of intermittent exotropia (IXT), but variability of stereoacuity has not been studied rigorously. The purpose of this study was to assess the variability of stereoacuity over one day in children with IXT. DESIGN:Prospective cohort study. METHODS:Twelve ch...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.10.028
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:Although the association of cystoid macular edema with peripheral choroidal melanoma has been studied previously, the pathogenesis of cystoid macular edema as evaluated by light and electron microscopy remains controversial. We evaluated the cause of cystoid macular edema at the retinal capillary level. METHOD...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73867-x
更新日期:1995-02-01 00:00:00
abstract::We evaluated the effect of a collagen shield on epithelial healing in keratectomy wounds in rabbit eyes. Superficial keratectomies 6 mm in diameter were created in 12 eyes of six rabbits. Six eyes received collagen shields every eight hours; six eyes received no treatment (control group). Epithelial healing was signif...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90428-5
更新日期:1989-11-15 00:00:00
abstract:PURPOSE:To determine the incidence of new chorioretinal lesions in children with toxoplasmosis diagnosed after, and therefore not treated during, their first year. DESIGN:Prospective longitudinal cohort study. METHODS:Thirty-eight children were evaluated in Chicago between 1981 and 2005 for new chorioretinal lesions....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.04.033
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To evaluate microbiota colonizing soft contact lenses (CL) in eyes with Boston type I keratoprosthesis (BKPro), and determine the prevalence of resistance to fourth-generation fluoroquinolone (FQ). DESIGN:Prospective, observational study. SUBJECTS:Patients with BKPro using CL as routine who were in postoperat...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.05.021
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:To compare 5-year visual acuity and refraction outcome in Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK) for Fuchs endothelial dystrophy (FED) or bullous keratopathy (BK) in Asian eyes. DESIGN:Prospective interventional case series. METHODS:We analyzed 828 cons...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.07.014
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To evaluate changes in postoperative refractive outcomes following combined phacoemulsification and pars plana vitrectomy for rhegmatogenous retinal detachment (RRD) compared with other retinal diseases. DESIGN:Retrospective observational case-control study. METHODS:A total of 55 patients who had combined sur...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.04.023
更新日期:2014-08-01 00:00:00
abstract::To study the retinal surface in the human eye in normal and diseased states we used laser scanning tomography. The confocal arrangement of the laser tomographic scanner permits examination of retinal topography in the axis perpendicular to the retinal surface. The eyes examined with the laser tomographic scanner inclu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90118-9
更新日期:1989-09-15 00:00:00
abstract:PURPOSE:To determine the type of herpes simplex virus in acute retinal necrosis syndrome associated with herpes simplex virus. METHODS:Herpes simplex virus type 1, herpes simplex virus type 2, varicella-zoster virus, Epstein-Barr virus, and cytomegalovirus were examined by polymerase chain reaction in intraocular spec...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00391-8
更新日期:2000-03-01 00:00:00
abstract::A retrospective study of 23 conjunctival melanomas using the Clark classification revealed that the three most common forms of melanoma described in the skin--lentigo maligna melanoma (Hutchinson's freckle with melanoma), superficial spreading melanoma, and nodular melanoma--can be recognized in the conjunctiva. As in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90487-6
更新日期:1976-09-01 00:00:00
abstract:PURPOSE:This study sought to compare the postoperative visual outcomes of toric implantable collamer lens (T-ICL) with toric Artiflex (T-Artiflex) lenses. DESIGN:Alternating treatment, contralateral eye matched clinical study. METHODS:This study compared 82 eyes of 41 patients with T-ICL lenses in one eye and toric A...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.06.021
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To evaluate the long-term risk of endothelial rejection, graft survival, and associated factors following penetrating keratoplasty (PK) for keratoconus, with and without prior resolved corneal hydrops. DESIGN:Retrospective cohort study. METHODS:Primary outcome measures were endothelial rejection-free survival...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.07.001
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To characterize spontaneous dislocation of the fluocinolone acetonide sustained release implant (Retisert; Bausch & Lomb) drug pellet from its strut. DESIGN:Retrospective, observational case series. METHODS:The medical records of 224 patients in whom 407 fluocinolone acetonide implants were placed by either o...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2015.01.031
更新日期:2015-05-01 00:00:00
abstract::Dipivefrin, an epinephrine prodromal drug, was used in conjunction with timolol maleate to evaluate the safety and effectiveness of combined therapy. Seventeen patients who had used timolol maleate for at least six months added dipivefrin (Group 1) and seven patients who had used dipivefrin for at least six months add...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90182-3
更新日期:1981-02-01 00:00:00
abstract:PURPOSE:To examine the safety and efficacy of combined phacoemulsification and glaucoma drainage implant surgery in providing reduction of intraocular pressure (IOP) and visual rehabilitation in eyes with refractory glaucoma and cataract. DESIGN:Interventional case series. METHODS:A retrospective chart review was per...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2003.08.036
更新日期:2004-02-01 00:00:00
abstract:PURPOSE:To determine whether residual hyperopia could be corrected postoperatively using the light adjustable lens technology in patients undergoing cataract surgery and light adjustable lens implantation. DESIGN:Prospective, nonrandomized clinical trial. METHODS:Fourteen eyes of 14 patients were studied. The manifes...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajo.2008.08.039
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To report a case of porphyria cutanea tarda presenting as cicatricial conjunctivitis. DESIGN:Observational study. METHODS:A 31-year-old man presented with bilateral inferior symblepharon, superior tarsal conjunctival scarring and concretions, and recurrent conjunctival and episcleral injection. RESULTS:Four ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01623-9
更新日期:2002-10-01 00:00:00
abstract:PURPOSE:To describe changes in the acquired immunodeficiency syndrome (AIDS) epidemic that are important to ophthalmologists, to provide an overview of issues relevant to current evaluation and treatment of human immunodeficiency virus (HIV)-related eye disease, and to identify problems related to the eye and vision th...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ajo.2007.12.001
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To determine whether a three-year fluocinolone acetonide sustained drug delivery system can be implanted safely at the same time that phacoemulsification and intraocular lens (IOL) implantation are performed for a visually significant cataract in eyes with uveitis. DESIGN:Retrospective, single-center case seri...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajo.2008.05.035
更新日期:2008-10-01 00:00:00
abstract:PURPOSE:To determine risk factors for poor visual acuity outcomes in patients with endogenous Klebsiella pneumoniae endophthalmitis. DESIGN:Retrospective case-control study. METHODS:We reviewed all consecutive patients diagnosed with endogenous Klebsiella pneumoniae endophthalmitis over 20 years. Data collected inclu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.08.036
更新日期:2011-02-01 00:00:00
abstract::Deposits resembling foreign-body giant cells, which can be seen on specular reflex slit-lamp examination, were studied in vivo with a wide-field specular microscope using a low-power dipping cone lens in three cases of posterior chamber lens implantation. The deposits seen as iris pigment on routine examination showed...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(85)90360-5
更新日期:1985-03-15 00:00:00
abstract:PURPOSE:To report a case of cancer-associated retinopathy associated with invasive thymoma. DESIGN:Interventional case report. METHOD:A 41-year-old Japanese woman was observed between February 1998 and May 2001. Ophthalmologic examinations and systemic examinations were performed. The patient received treatment inclu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01598-2
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:To describe the ocular complications of smallpox vaccination and to discuss potential therapeutic options. DESIGN:Review of pertinent medical literature and recent treatment recommendations of the Centers for Disease Control and Prevention. RESULTS:After immunization against smallpox, vaccinia infection of th...
journal_title:American journal of ophthalmology
pub_type: 历史文章,杂志文章,评审
doi:10.1016/s0002-9394(03)00293-9
更新日期:2003-08-01 00:00:00