Abstract:
:A recent paper in Cell (Yao et al., 2006) and two papers in Developmental Cell (Tenzen et al., 2006; Zhang et al., 2006) identify a new receptor component for Hedgehog, a key morphogen in embryonic development. Many other proteins that bind to Hedgehog in the extracellular matrix or on the cell surface have been identified. In light of these recent discoveries, we discuss how these factors control the stability, transport, reception, and availability of Hedgehog in modulating Hedgehog-mediated responses.
journal_name
Celljournal_title
Cellauthors
Wilson CW,Chuang PTdoi
10.1016/j.cell.2006.04.016subject
Has Abstractpub_date
2006-05-05 00:00:00pages
435-8issue
3eissn
0092-8674issn
1097-4172pii
S0092-8674(06)00497-1journal_volume
125pub_type
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