Abstract:
OBJECTIVES:Since little investigation has been undertaken to determine if alpha1-blockers should be given continuously to sustain their efficacy, we conducted a pilot study to determine symptom change following discontinuation of tamsulosin after an initial improvement in symptoms in men with lower urinary tract symptoms (LUTS). PATIENTS AND METHODS:Thirty-three of 78 patients with mild-to-moderate prostate hyperplasia, who had symptom improvement according to the International Prostate Symptom Score (IPSS) to <10 or the quality of life (QOL) index to < or =3 after initial treatment with tamsulosin, were enrolled in this study. Subjective parameters (IPSS and QOL index) and objective parameters (maximum and mean urinary flow rates) were evaluated at baseline and after initial treatment, and 4, 8, 12 and 24 weeks after discontinuing tamsulosin. RESULTS:The rates of successful discontinuation of tamsulosin were high throughout the follow-up period, i.e., 80.6% at 4 weeks, 80.6% at 8 weeks, 80.0% at 12 weeks, and 68.9% at 24 weeks. Temporary worsening in both subjective and objective parameters was observed only at 4 weeks; however, these parameters recovered to almost post-treatment levels at 24 weeks. CONCLUSION:The present study suggests that continuous treatment is not always needed to maintain urinary symptom relief in a specific subset of patients who felt symptom improvement after initial treatment with tamsulosin.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Kobayashi M,Tokue A,Morita Tdoi
10.1159/000092052subject
Has Abstractpub_date
2006-01-01 00:00:00pages
304-8issue
4eissn
0042-1138issn
1423-0399pii
92052journal_volume
76pub_type
杂志文章abstract::Sex-dependent stone formation following portacaval shunt (PCS) was investigated in 82 male and 71 female Sprague-Dawley rats. 72.6% of male PCS rats and none of the female PCS rats developed urolithiasis, in 90.2%, potassium-hydrogen-urate stones formed. Hormonal analysis revealed significant alterations in steroid ho...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282544
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:Genetic variants of vitamin D receptor (VDR) were implicated in urolithiasis susceptibility in several case-control studies. However, these studies so far have provided conflicting results. In order to investigate the potential relationship, a meta-analysis was conducted. METHODS:Eligible studies were retrie...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000323949
更新日期:2011-01-01 00:00:00
abstract::From July 1992 to April 1994, 70 patients with prostatic cancer underwent laparoscopic pelvic lymph-node dissection (LPLD) before retropubic radical prostatectomy or afterloading therapy in our clinic. After an initial learning phase, the accuracy of LPLD was excellent, with only 3.0% residual nodes and no false-negat...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282756
更新日期:1995-01-01 00:00:00
abstract:INTRODUCTION:Urologists have to master a variety of techniques to be able to offer the most appropriate surgical stone treatment for each individual patient. Therefore, we performed a survey among board-certified Swiss urologists to assess the availability of the different surgical methods, the current practices of sur...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000502806
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Planification of living donor nephrectomy requires exact knowledge of the renal vascular architecture because of the high prevalence of anatomical variants. After magnetic resonance angiography (MRA) challenged CT angiography for preoperative assessment over the last years, we revisit in this study the rel...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000273467
更新日期:2010-01-01 00:00:00
abstract::Biopsies of 9 testicular tumors were examined for the presence of cytoplasmic receptor proteins for estrogens, progestins, androgens, and glucocorticoids. Using an arbitrary threshold value of 10 fmol/mg cytosol protein for a postive assay, only 1 of 9 tumors was estrogen-receptor positive. However, no receptor-specif...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281072
更新日期:1985-01-01 00:00:00
abstract::We examined a 46-year-old male patient with idiopathic myelofibrosis diagnosed 28 months earlier. After chemotherapy and irradiation, CT showed nonnodular, soft tissue masses in the renal hilum, pelvicaliceal system, perirenal and periureteral spaces. Ultrasound-guided biopsy showed extramedullary hematopoiesis (EMH)....
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000087809
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility and performance of radical cystectomy with urinary diversion using exclusively regional anesthesia (i.e. combined spinal thoracic epidural anesthesia, CSTEA), avoiding the adverse effects of general anesthesia. MATERIALS AND METHODS:In our hospital, radical cystectomy with extended ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000348542
更新日期:2013-01-01 00:00:00
abstract:AIM:To analyze demographics, perioperative mortality and overall survival of radical cystectomy (RC) in patients aged 70+ years in Austria in a nation-wide registry cohort. PATIENTS AND METHODS:All patients >69 years who underwent RC in public hospitals (covering >95% of all surgical procedures) in Austria between 199...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000316100
更新日期:2010-01-01 00:00:00
abstract::In 1 out of 56 patients, orchiectomized in the course of treatment for prostatic carcinoma, metastatic growth in the testis was found. This uncommon metastatic spread is a sign of advanced disease. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281859
更新日期:1987-01-01 00:00:00
abstract::We report the first case of aspergillus mycotic aneurysm as a sequel to concomitant prostatic and renal aspergillosis. The patient had undergone left nephrectomy and transurethral resection of prostate for aspergillus infection one year ago. He again presented with LUTS and backache and clinical examination showed vis...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000056561
更新日期:2001-01-01 00:00:00
abstract::Renal pseudoaneurysms are a well-documented complication following trauma or after percutaneous biopsy. When symptomatic, patients present with hematuria and deteriorating renal function. We present the case of a 62-year-old man who, due to development of a pseudoaneurysm, presented with gross hematuria 10 days after ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030536
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical and demographic findings of children with urolithiasis in eastern Turkey. METHODS:We retrospectively reviewed the medical records of 67 children with urolithiasis for clinical and laboratory data. RESULTS:Mean age at the time of diagnosis was 39.1 +/- 41.2 months. Complaints at admi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000230027
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Phosphatidylinositol 3-kinase (PI3K)-AKT signaling is a well-characterized pathway involved in the control of cell proliferation, apoptosis and oncogenesis. LY294002 is a commonly used pharmacologic inhibitor which acts at the ATP-binding site of the PI3K enzyme, thus selectively inhibiting the PI3K-AKT nexu...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000322849
更新日期:2011-01-01 00:00:00
abstract::To our knowledge only a few cases of renal milk of calcium have been reported. We have encountered 5 such patients. The diagnosis depends upon the demonstration of half-moon-shaped calcification in the lateral decubitus or upright roentgenograms. This condition should be differentiated from a renal calculus to avoid u...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000282538
更新日期:1993-01-01 00:00:00
abstract::The anterior nutcracker syndrome is defined by the compression of the left renal vein between the aorta and superior mesenteric artery, usually related to the occurrence of hematuria. We report the case of an uncommon complication of the nutcracker syndrome. A 75-year-old woman was referred to our institution for left...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000381270
更新日期:2016-01-01 00:00:00
abstract::In order to investigate the influence of the endorphins on lower urinary tract function we antagonized the endogenous opiates with naloxone. We performed urodynamic examination in 17 incontinent women, administered intravenously 0.4 mg naloxone, and repeated the urodynamic examination. Bladder volume and pressure were...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280969
更新日期:1984-01-01 00:00:00
abstract::Aneurysmectomy and renal angioplasty were performed on a 14-year-old Japanese male and the blood pressure was within normal values 3 years after this surgery. Measurement of renal blood flow was facilitated by using 133Xe washout technique. This incidence is the eighth such case to be reported from Japan. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280073
更新日期:1976-01-01 00:00:00
abstract::Stereology was shown in several studies to be a relevant method to study the quantitative amount of tissue and cell compartments of normal and pathological altered prostatic tissue. A morphological comparison of the rat (ventral lobe), dog and human prostate was performed by quantitative morphology. In comparing the l...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280309
更新日期:1980-01-01 00:00:00
abstract::Extrarenal calyces are an extremely rare entity and only a few cases have been reported worldwide. We report a case with extrarenal calyces and give a brief review of the literature. Awareness of this rare entity can prevent inadvertent injury to the pelvicalyceal system during surgery. ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000072690
更新日期:2003-01-01 00:00:00
abstract::During 1986 and 1987, 47 patients with renal cell carcinoma were evaluated preoperatively with CT, angiography and MRI. The preoperative tumor stage (T), lymph node metastases and venous involvement determined with the three methods were compared to the operative and histopathological findings. For T stage, angiograph...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282219
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:Detection of DNA hypermethylation is emerging as a novel molecular biomarker for different malignancies. We intend to define whether a hypermethylation profile of patients with prostate cancer (PCa) predicts biochemical recurrence (BCR) after radical prostatectomy (RP). MATERIAL AND METHODS:Genome-wide methyla...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000446446
更新日期:2016-01-01 00:00:00
abstract::Testicular sperm extraction and intracytoplasmic sperm injection (TESE-ICSI) is a frequently used therapeutic option in azoospermic males. Genetic imprinting is a mechanism of gene regulation - mediated by the methylation of deoxyribonucleic acids (DNA) - by which only one of the parental copies of a gene is expressed...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000050972
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:The initial objective of this renal cancer study was to identify gene sets in clear cell renal cell carcinoma (ccRCC) to support grading of ccRCC histopathology. MATERIALS AND METHODS:Preselected ccRCC tumor tissues of grade 1 (G1, n = 14) and grade 3 (G3, n = 15) as well es 14 normal kidney tissues thereof ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000328196
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:Chronic renal damage due to tubulointerstitial fibrosis is one of several complications of posterior urethral valves in a significant number of children. As activation of the renin-angiotensin system plays an important role in this injury, we conducted this study to investigate whether administration of captopr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000098078
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The flexible ureterorenoscope (URS) and associated devices have developed rapidly. However, despite its therapeutic benefits, URS may be associated with some complications. To the best of our knowledge, there are no studies discussing the complications of flexURS during the learning curve. METHODS:A retrosp...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000368617
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The main purpose of the study was to identify and quantify clinical variables which predisposed incorrect diagnosis based on ultrasonography (US) and computed tomography (CT) findings in the patients with suppurative renal infections. PATIENTS AND METHODS:A retrospective review of radiological records of pa...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000132697
更新日期:2008-01-01 00:00:00
abstract:AIMS:To determine the optimal place to apply the local anesthetic agent and to investigate the efficacy of lidocaine-prilocaine cream on the perianal and intrarectal region during prostate biopsy. METHODS:The study included 80 patients. Patients were randomized into four groups: group 1 served as the control group and...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000209354
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To compare the safety and efficacy of standard-tract combined with mini-tract to single standard-tract in percutaneous nephrolithotomy (PCNL) for renal staghorn calculi. METHODS:The records of 216 patients with staghorn calculi (110 (50.9%) had complete and 106 (49.1%) had partial) who received PCNL were revie...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000354427
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the therapeutic efficacy of a steroid switch from prednisone to dexamethasone in Asians with metastatic castration-resistant prostate cancer (mCRPC) that progressed after docetaxel chemotherapy. METHODS:This study included postdocetaxel patients with mCRPC treated with abiraterone acetate combine...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000509882
更新日期:2020-08-13 00:00:00