Anti-microbial active composite nanoparticles with magnetic core and photocatalytic shell: TiO2-NiFe2O4 biomaterial system.

abstract：:The tricuspid valve ensures unidirectional blood flow from the right atrium to the right ventricle. The three tricuspid leaflets operate within a dynamic stress environment of shear, bending, tensile, and compressive forces, which is cyclically repeated nearly three billion times in a lifetime. Ostensibly, the microst...

journal_title：Acta biomaterialia

authors： Meador WD,Mathur M,Sugerman GP,Jazwiec T,Malinowski M,Bersi MR,Timek TA,Rausch MK

更新日期：2020-01-15 00:00:00

abstract：:Evidence that macrophages can play a role in accelerating corrosion in CoCrMo alloy in total hip replacement (THR) interfaces leads to questions regarding the underlying cellular mechanisms and immunological responses. Hence, we evaluated the role of macrophages in corrosion processes using the cell culture supernatan...

journal_title：Acta biomaterialia

authors： Bijukumar DR,Salunkhe S,Zheng G,Barba M,Hall DJ,Pourzal R,Mathew MT

更新日期：2020-01-01 00:00:00

abstract：:Despite the rapid progress which has been made in hepatocellular carcinoma (HCC) chemotherapeutics, recurrence of liver cancer still remains a barrier to achieve satisfying prognosis. Herein, we aimed to decipher the role of berberine (BER) in chemotherapy-exacerbated HCC repopulation via developing a nanocarrier co-d...

journal_title：Acta biomaterialia

authors： Zhang F,Jia Y,Zheng X,Shao D,Zhao Y,Wang Z,Dawulieti J,Liu W,Sun M,Sun W,Pan Y,Cui L,Wang Y,He K,Zhang M,Li J,Dong WF,Chen L

更新日期：2019-12-01 00:00:00

abstract：:The formation of new blood vessels has been shown to be fundamental in the repair of many damaged tissues, and we have recently shown that the adult human periodontal ligament contains multipotent stem/progenitor cells that are capable of undergoing vasculogenic and angiogenic differentiation in vitro and ex vivo. Ena...

journal_title：Acta biomaterialia

authors： Amin HD,Olsen I,Knowles J,Dard M,Donos N

更新日期：2014-05-01 00:00:00

abstract：:Immobilization of phosphoproteins on a collagen matrix is important for the induction of intrafibrillar apatite mineralization. Unlike phosphate esters, polyphosphonic acid has no reactive sites for covalent binding to collagen amine groups. Binding of poly(vinyl phosphonic acid) (PVPA), a biomimetic templating analog...

journal_title：Acta biomaterialia

authors： Gu LS,Kim YK,Liu Y,Takahashi K,Arun S,Wimmer CE,Osorio R,Ling JQ,Looney SW,Pashley DH,Tay FR

更新日期：2011-01-01 00:00:00

abstract：:Tissue-engineered constructs can be fabricated by the assembly of smaller building blocks in order to mimic much of the native biology that is often made from repeating functional units. Our aim was to realize a three-dimensional (3-D) tissue-like construct in vitro by inducing the assembly of functional micrometric t...

journal_title：Acta biomaterialia

authors： Palmiero C,Imparato G,Urciuolo F,Netti P

更新日期：2010-07-01 00:00:00

abstract：:Surgical removal remains the main clinical approach to treat breast cancer, although risks including high local recurrence of cancer and loss of breast tissues are the threats for the survival and quality of life of patients after surgery. In this study, bifunctional scaffold based on dopamine-modified alginate and po...

journal_title：Acta biomaterialia

authors： Luo Y,Wei X,Wan Y,Lin X,Wang Z,Huang P

更新日期：2019-07-01 00:00:00

abstract：:Clinically, hypertrophic scarring (HS) is a major concern for patients and has been a challenge for surgeons, as there is a lack of treatments that can intervene early in the formation of HS. This study reports on a Chinese drug, 20(R)-ginsenoside Rg3 (GS-Rg3), which can inhibit in vivo the early formation of HS and l...

journal_title：Acta biomaterialia

authors： Cheng L,Sun X,Hu C,Jin R,Sun B,Shi Y,Zhang L,Cui W,Zhang Y

更新日期：2013-12-01 00:00:00

abstract：:Intervertebral disc (IVD) disorders and age-related degeneration are believed to contribute to lower back pain. There is significant interest in cell-based strategies for regenerating the nucleus pulposus (NP) region of the disc; however, few scaffolds have been evaluated for their ability to promote or maintain an im...

journal_title：Acta biomaterialia

authors： Francisco AT,Hwang PY,Jeong CG,Jing L,Chen J,Setton LA

更新日期：2014-03-01 00:00:00

abstract：UNLABELLED:The generation of tissue-engineered blood vessel substitutes remains an ongoing challenge for cardiovascular tissue engineering. Full biocompatibility and immediate availability have emerged as central issues for clinical use. To address these issues, we developed a technique that allows the generation of hi...

journal_title：Acta biomaterialia

authors： Aper T,Wilhelmi M,Gebhardt C,Hoeffler K,Benecke N,Hilfiker A,Haverich A

更新日期：2016-01-01 00:00:00

abstract：:Decellularized nerve, or acellular nerve allografts (ANAs), are an increasingly used alternative to nerve autografts to repair nerve gaps to facilitate regeneration. The adaptive immune system, specifically T cells, plays a role in promoting regeneration upon these ANA scaffolds. However, how T cells promote regenerat...

journal_title：Acta biomaterialia

authors： Pan D,Hunter DA,Schellhardt L,Fuchs A,Halevi AE,Snyder-Warwick AK,Mackinnon SE,Wood MD

更新日期：2020-08-01 00:00:00

abstract：:Aortic valve calcification leads to the deposition of calcium phosphate minerals in the extracellular matrix of the aortic valve leaflets. The mineral deposits can severely narrow the opening of the aortic valve, leading to aortic stenosis. There are no therapies to halt or slow down disease progression and the mechan...

journal_title：Acta biomaterialia

authors： Gourgas O,Khan K,Schwertani A,Cerruti M

更新日期：2020-04-01 00:00:00

abstract：:Anisotropic scaffolds with the typical structure of lamellar, aligned and continuous pores were successfully achieved by the directional solidification of water-based β-tricalcium phosphate (β-TCP) suspensions. Adjustable porosities from 49 to 82%, tunable pore widths from 8 to 50μm and linked ceramic cells with wall ...

journal_title：Acta biomaterialia

authors： Flauder S,Gbureck U,Müller FA

更新日期：2014-12-01 00:00:00

abstract：:Strombus gigas (conch) shells and Tridacna gigas (Giant clam) shells have dense, tailored structures that impart excellent mechanical properties to these shells. In this investigation, conch and clam seashells were converted to hydroxyapatite (HAP) by a hydrothermal method at different temperatures and for different c...

journal_title：Acta biomaterialia

authors： Vecchio KS,Zhang X,Massie JB,Wang M,Kim CW

更新日期：2007-11-01 00:00:00

abstract：:The management of diabetic wounds remains a major therapeutic challenge in clinics. Herein, we report a personalized treatment using 3D scaffolds consisting of radially or vertically aligned nanofibers in combination with bone marrow mesenchymal stem cells (BMSCs). The 3D scaffolds have customizable sizes, depths, and...

journal_title：Acta biomaterialia

authors： Chen S,Wang H,Su Y,John JV,McCarthy A,Wong SL,Xie J

更新日期：2020-05-01 00:00:00

abstract：UNLABELLED:The development of scaffolds for bone filling of large defects requires an understanding of angiogenesis and vascular guidance, which are crucial processes for bone formation and healing. There are few investigations on the ability of a scaffold to support blood vessel guidance and it this is of great import...

journal_title：Acta biomaterialia

authors： Magnaudeix A,Usseglio J,Lasgorceix M,Lalloue F,Damia C,Brie J,Pascaud-Mathieu P,Champion E

更新日期：2016-07-01 00:00:00

abstract：:A series of six copolymeric families, P(AN-co-MTAs) with various molar fractions of acrylonitrile (fAN) and methacrylates (fMTA) based on 1,3-thiazole and 1,2,3-triazole pendant groups with several spacers of different length and nature (alkyl or succinic), have been synthesized by conventional radical polymerization....

journal_title：Acta biomaterialia

authors： Tejero R,Gutiérrez B,López D,López-Fabal F,Gómez-Garcés JL,Fernández-García M

更新日期：2015-10-01 00:00:00

abstract：:Sr and CO3 co-substituted hydroxyapatite (SrCHA) nanopowder was synthesized by neutralization. The powder was characterized. The improved solubility in Hanks' balanced solution of SrCHA granules (400-600 microm of dimensional range), potentially usable as bone filler, was assessed and compared with that of an analogou...

journal_title：Acta biomaterialia

authors： Landi E,Sprio S,Sandri M,Celotti G,Tampieri A

更新日期：2008-05-01 00:00:00

abstract：:Synthetic three-dimensional scaffolds for cell and tissue engineering routinely utilize peptide ligands to provide sites for cell adhesion and to promote cellular activity. Given the fact that recent studies have dedicated great attention to the mechanisms by which cell behavior is influenced by various ligands and sc...

journal_title：Acta biomaterialia

authors： Zustiak SP,Durbal R,Leach JB

更新日期：2010-09-01 00:00:00

abstract：:Electrical stimulation of the muscle has been proven efficacious in preventing atrophy and/or reanimating paralyzed muscles. Intramuscular electrodes made from metals have significantly higher Young's Moduli than the muscle tissues, which has the potential to cause chronic inflammation and decrease device performance....

journal_title：Acta biomaterialia

authors： Zheng XS,Griffith AY,Chang E,Looker MJ,Fisher LE,Clapsaddle B,Cui XT

更新日期：2020-02-01 00:00:00

abstract：:Photodynamic therapy (PDT) generates highly toxic reactive oxygen species (ROS) during noninvasive cancer treatment. MutT homolog 1 (MTH1) protein is a DNA oxidative damage repair protease and suppressing its function may provide a strategy to enhance PDT efficacy by improving cellular sensitivity to ROS. A nanopartic...

journal_title：Acta biomaterialia

authors： Huang X,Chen J,Wu W,Yang W,Zhong B,Qing X,Shao Z

更新日期：2020-06-01 00:00:00

abstract：:Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering, regenerative medicine, and drug delivery applications due to their specific characteristics. These biomaterials benefit from retaining a large amount of water, effective mass transfer, similarity to natural tissues and the abili...

journal_title：Acta biomaterialia

authors： Vedadghavami A,Minooei F,Mohammadi MH,Khetani S,Rezaei Kolahchi A,Mashayekhan S,Sanati-Nezhad A

更新日期：2017-10-15 00:00:00

abstract：:Using monoclonal antibodies to block tumor angiogenesis has yielded effective antitumor effects. However, this treatment method has long cycles and is very expensive; therefore, its long-term and extensive application is limited. In this study, we developed a nanovaccine using bacterial biomembranes as carriers for an...

journal_title：Acta biomaterialia

authors： Huang W,Shu C,Hua L,Zhao Y,Xie H,Qi J,Gao F,Gao R,Chen Y,Zhang Q,Li W,Yuan M,Ye C,Ma Y

更新日期：2020-05-01 00:00:00

abstract：:Differentiation of stem cells into functional replacement cells and tissues is a major goal of the regenerative medicine field. However, one limitation has been organization of differentiated cells into multi-cellular, three-dimensional assemblies. The islets of Langerhans contain many endocrine and non-endocrine cell...

journal_title：Acta biomaterialia

authors： Augsornworawat P,Velazco-Cruz L,Song J,Millman JR

更新日期：2019-10-01 00:00:00

abstract：:Prosthetic joint infection (PJI) is a well-known and persisting problem. Active release coatings have promise to provide early protection to an implant by eradicating small colony biofilm contaminants or planktonic bacteria that can form biofilm. Traditional antibiotics can be limited as active release agents in that ...

journal_title：Acta biomaterialia

authors： Williams DL,Epperson RT,Ashton NN,Taylor NB,Kawaguchi B,Olsen RE,Haussener TJ,Sebahar PR,Allyn G,Looper RE

更新日期：2019-07-15 00:00:00

abstract：:Abnormal wound healing caused by the over-expression of collagen and fibronectin leads to fibrosis, the major complication of all treatment modalities. A three-layer nanofiber scaffold was designed, optimized, and fabricated. This scaffold comprised two supportive polycaprolactone (PCL)-chitosan layers on the sides an...

journal_title：Acta biomaterialia

authors： Chogan F,Mirmajidi T,Rezayan AH,Sharifi AM,Ghahary A,Nourmohammadi J,Kamali A,Rahaie M

更新日期：2020-09-01 00:00:00

abstract：:Implant-associated infections is one of the most challenging post-operative complications in bone-related implantations. To tackle this clinical issue, we developed a low-cost and durable surface coating for medical grade titanium implants that uses positively charged silane molecules. The in vitro antimicrobial tests...

journal_title：Acta biomaterialia

authors： Shen J,Gao P,Han S,Kao RYT,Wu S,Liu X,Qian S,Chu PK,Cheung KMC,Yeung KWK

更新日期：2020-09-15 00:00:00

abstract：:Natural silk fiber spun by the silkworm Bombyx mori is widely used not only for textile materials, but also for biofunctional materials. In the present study, we genetically engineered an advanced silk material, named hSFSV, using a transgenic silkworm, in which the recombinant human acidic fibroblast growth factor (h...

journal_title：Acta biomaterialia

authors： Wang F,Xu H,Wang Y,Wang R,Yuan L,Ding H,Song C,Ma S,Peng Z,Peng Z,Zhao P,Xia Q

更新日期：2014-12-01 00:00:00

abstract：:Extracellular matrix (ECM) is crucial to many aspects of vascular morphogenesis and maintenance of vasculature function. Currently the recapitulation of angiogenic ECM microenvironment is still challenging, due mainly to its diverse components and complex organization. Here we investigate the angiogenic potential of h...

journal_title：Acta biomaterialia

authors： Du P,Suhaeri M,Ha SS,Oh SJ,Kim SH,Park K

更新日期：2017-05-01 00:00:00

abstract：:Implant-derived material from metal-on-metal (MOM) hip arthroplasties may be responsible for an unexplained tissue inflammatory response. The chemical form of the metal species in the tissues is predominantly chromium (Cr), but the currently used techniques have not been able to determine whether this is Cr(III) phosp...

journal_title：Acta biomaterialia

authors： Hart AJ,Quinn PD,Sampson B,Sandison A,Atkinson KD,Skinner JA,Powell JJ,Mosselmans JF

更新日期：2010-11-01 00:00:00