Abstract：
:Aniline of unknown purity has been reported to induce spleen hemangiosarcoma in rats. Aniline has been found to be negative in terms of mutagenicity in both bacteria and yeasts. We have found that both commercial (already rather pure) and repurified aniline are clearly positive to a similar extent in inducing DNA damage in vivo in liver and kidney of rats. Both the commercial and repurified product are also clearly positive in induction of sister chromatid exchanges in vivo in male Swiss mice bone marrow cells. Liver, kidney, and bone marrow DNA damage was absent in male Swiss mice.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Parodi S,Pala M,Russo P,Zunino A,Balbi C,Albini A,Valerio F,Cimberle MR,Santi Lsubject
Has Abstractpub_date
1982-06-01 00:00:00pages
2277-83issue
6eissn
0008-5472issn
1538-7445journal_volume
42pub_type
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