Abstract:
:Hamsters exhibited a circadian variation in metabolic activity determined by [14C]2-deoxyglucose uptake in the suprachiasmatic nuclei, as has been previously reported for rats. The 13-line ground squirrel, a diurnal rodent, did not show a circadian variation in metabolic activity. The data are consistent with the hypothesis that there is a basic difference in the functional organization of the suprachiasmatic nuclei in nocturnal and diurnal animals.
journal_name
Brain Resjournal_title
Brain researchauthors
Flood DG,Gibbs FPdoi
10.1016/0006-8993(82)90626-6subject
Has Abstractpub_date
1982-01-28 00:00:00pages
200-5issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(82)90626-6journal_volume
232pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Intracellular and extracellular recordings from CA3 hippocampal neurons in vitro were used to study the ability of several NMDA (N-methyl-D-aspartate) receptor antagonists to suppress epileptiform bursts induced by NMDA and convulsants not thought to act at NMDA receptors. The antagonists, APV (D-2-amino-5-phosphonova...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90642-7
更新日期:1988-09-06 00:00:00
abstract::Radioligand-binding studies were performed to ascertain the actions of noribogaine, a suspected metabolite of ibogaine, on opioid receptors. Consistent with previous results, ibogaine showed highest affinity for kappa opioid receptors (Ki = 3.77 +/- 0.81 microM), less affinity for mu receptors (Ki = 11.04 +/- 0.66 mic...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00123-8
更新日期:1995-03-27 00:00:00
abstract::We investigated the effects of inverting facial contour (hair and chin) and features (eyes, nose and mouth) on processing for static and dynamic face perception using magnetoencephalography (MEG). We used apparent motion, in which the first stimulus (S1) was replaced by a second stimulus (S2) with no interstimulus int...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.01.091
更新日期:2011-04-06 00:00:00
abstract::Using a double-labelling procedure, morphological relationships existing between dopaminergic and indoleaminergic neuronal systems in the rat brain were investigated. First, thanks to a tryptamine (T) antiserum, we visualized this indoleamine in all mesencephalic regions and showed that the T-immunoreactivity (IR) see...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91182-g
更新日期:1990-03-26 00:00:00
abstract::Transient foci of epileptiform alteration in neuronal population activity were induced by microinjection of strychnine sulfate into different layers of cat striate cortex. Potentials evoked by visual field-specific photic stimulation were recorded from microelectrodes at the injection site and in adjacent laminae. Epi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90938-2
更新日期:1985-08-12 00:00:00
abstract::Medium conditioned by NG108-15 neuroblastoma x glioma hybrid cells contains a factor which increases the number of acetylcholine receptor (AChR) aggregates on cultured myotubes. Protease digestion indicates that the AChR aggregation factor is a protein, and the molecular weight is from 150,000 to 250,000 daltons as es...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90161-x
更新日期:1981-03-30 00:00:00
abstract::Retrogradely labeled vestibulo-ocular neurons (VOR) that also stain with antibodies for the excitatory amino acid neurotransmitters glutamate (GLU-LI) or aspartate (ASP-LI) were studied. VOR neurons that contained GLU-LI or ASP-LI label were identified in the medial (MVN) and superior (SVN) vestibular nuclei, and cell...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90215-h
更新日期:1991-07-19 00:00:00
abstract::The localization of human hand primary motor area (M1) has been the object of several studies during the last decades. EEG source analysis, functional magnetic resonance imaging (fMRI) and focal transcranial magnetic stimulation (TMS) are non-invasive methods for localizing M1 with good accuracy compared to direct ele...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.10.042
更新日期:2010-01-13 00:00:00
abstract::Previous observations show that neonatal removal of nerve growth factor results in an increased number of fine dorsal root axons in the adult animal. The present study shows that the same treatment results in 49% more axons in the adult tract of Lissauer, which is an area of spinal white matter that contains predomina...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90262-4
更新日期:1988-10-04 00:00:00
abstract::Male rats were treated with barbital in their drinking fluid for about 40 weeks (daily dose 200 mg/kg). The treatment was stopped on day 0 and the number of muscarinic binding sites was measured in 3 brain parts (striatum; cortex and hippocampus; medulla oblongata and midbrain) during the abstinence with labeled quinu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90146-9
更新日期:1982-08-19 00:00:00
abstract::The firing patterns of up to 4 concurrently active masseter motor units were studied with intramuscular electrodes during a continuous isometric contraction of 15 min duration, in which the subject maintained the mean firing rate of one selected unit at 10 Hz. With this paradigm the net excitation (i.e. mean firing ra...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90467-a
更新日期:1991-05-24 00:00:00
abstract::Neuropeptide Y (NPY) has been detected immunocytochemically in cerebral cortex and subcortical white matter of the primate frontal, parietal, temporal, and occipital lobes. Because little is known about NPY in the primate insular lobe and because peptides play an important role in normal neuronal functioning and alter...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91245-n
更新日期:1993-02-19 00:00:00
abstract::A method to study the protein binding patterns of trace elements in human cerebrospinal fluid (CSF) is described. Proteins in CSF samples were separated by size exclusion chromatography combined with high performance liquid chromatography (SEC-HPLC). The column was calibrated to separate proteins in the molecular weig...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.08.004
更新日期:2007-10-12 00:00:00
abstract::Experiments have been performed on pentobarbitone anesthetized or decerebrated rats. The nature of the synchronous rhythmical activity which occurs in the inferior olive following the electrophoretic or systemic administration of harmaline, harmine, dihydro-beta-erythroidine and various other compounds, is described. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90471-6
更新日期:1976-01-23 00:00:00
abstract::Twice daily injections of 1.0 or 5.0 mg/kg D-amphetamine for 6 consecutive days differentially affected the response of dopaminergic neurons in the substantia nigra pars compacta to challenge injections of apomorphine on the following day. Thus, whereas treatment with the high amphetamine dose produced a dramatic shif...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90691-7
更新日期:1984-10-29 00:00:00
abstract::Serotonin (5HT) is thought to reset the biological clock in the suprachiasmatic nuclei (SCN) in vitro through a postsynaptic 5HT-1a receptor. Thus we examined 5HT receptor gene expression in the SCN by in situ hybridization. On film autoradiograms, 5HT-1c receptor mRNA showed intense SCN hybridization, while 5HT-1b re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90789-p
更新日期:1993-04-09 00:00:00
abstract::Horeradish peroxidase was injected at multiple sites in the mandibular and sublingual salivary glands in order to label the preganglionic salivatory neurons in the brain stem. The same injections resulted in retrograde labeling of the sympathetic and sensory neurons that project to these glands. Labeled fusiform and m...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90092-x
更新日期:1980-05-12 00:00:00
abstract::Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a reliable seed-based analysis of the resting-state brain activity to comprehensively delineate the subdivisions of striatal functional connectivity implicated in internet gaming disorder. Amon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.12.042
更新日期:2015-03-30 00:00:00
abstract::Painful experience is a complex entity made up of sensory, affective, motivational and cognitive dimensions. The neural mechanisms involved in pain perception acts in a serial and a parallel way, discriminating and locating the original stimulus and also integrating the affective feeling, involved in a special situati...
journal_title:Brain research
pub_type: 杂志文章,评审
doi:10.1016/j.brainres.2003.10.073
更新日期:2004-03-12 00:00:00
abstract:BACKGROUND:Diminished dopaminergic neurotransmission contributes to decreased reward and negative eating behaviors in obesity. Bariatric surgery is the most effective therapy for obesity and rapidly reduces hunger and improves satiety through unknown mechanisms. We hypothesized that dopaminergic neurotransmission would...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.03.064
更新日期:2010-09-02 00:00:00
abstract::The distribution of inositol 1,4,5-trisphosphate (InsP3) 3-kinase was studied in the adult rat brain, using polyclonal antibodies raised against the purified 50,000-Da rat brain enzyme by immunohistochemistry and Western blot, in addition to enzymatic assay. Immunohistochemically, the enzyme was detected in neurons, w...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91622-8
更新日期:1991-01-25 00:00:00
abstract::Changes in the astrocytic cytoskeleton were examined in amygdala kindled rats using immunocytochemical techniques. One week following kindling, there was a dramatic increase in immunoreactivity to glial fibrillary acidic protein and vimentin in astrocytes throughout amygdala, pyriform cortex and hippocampus bilaterall...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91694-a
更新日期:1992-10-02 00:00:00
abstract::Oral ENA713 (0.5, 1.5 and 4.5 mg/kg), an acetylcholinesterase inhibitor (AChEI), dose-dependently enhanced extracellular acetylcholine concentrations in the hippocampus of freely moving rats. This effect was paralleled by changes in both noradrenergic and dopaminergic transmission. In particular, ENA713 significantly ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02266-6
更新日期:2000-05-26 00:00:00
abstract::Prenatal exposure to opiates, which is invariably followed by postnatal withdrawal, can affect cognitive performance. To further characterize these effects, we examined radial 8-arm maze performance and expression of brain derived neurotrophic factor (BDNF) in male rats prenatally exposed to the opiate l-alpha-acetylm...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.01.020
更新日期:2008-03-10 00:00:00
abstract::Specific binding of [3H]naloxone to rat brain tissue in vitro was inhibited by the excitant organochlorinated insecticides (OCI), by ether (E) and octanol (OCT), and by the convulsant indoklon (IND) and its anesthetic isomer, isoindoklon (ISO). In the presence of 100 mM NaCl the inhibition of naloxone binding by E, OC...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90277-8
更新日期:1981-08-24 00:00:00
abstract::The importance of Na+/Ca2+ exchangers in the regulation of the physiological and pathological functions of the nervous system has been widely recognized. In this study, we used primary cultured E14.5 cortical neurons as a model system to study the possible roles of the reverse mode Na+/Ca2+ exchange activity in neurot...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.01.042
更新日期:2008-03-27 00:00:00
abstract::Although platelet-derived growth factor (PDGF)-BB activates PDGF receptor-beta (PDGFR-beta) and, in turn, inhibits the glutamate N-methyl-D-aspartate (NMDA) receptor function, whether PDGF-BB modulates the CNS function mediated by another glutamate receptors, alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (A...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.05.037
更新日期:2007-07-23 00:00:00
abstract::Picrotoxin-induced epileptiform activity was examined in neocortical slices prepared from 8- to 15-day-old rats. This activity consisted of spontaneous bursts of 3-5 discharges that resembled interictal spikes and were interspersed with ictal-like paroxysms lasting 10-30 s. Measurements of extracellular potassium ([K+...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(87)90036-8
更新日期:1987-12-01 00:00:00
abstract:BACKGROUND:Toll-like receptor 4 (TLR4) is an important mediator of the innate immune response. It significantly contributes to neuroinflammation and may be involved in ischemic tolerance. It is unknown how cerebral ischemia in the cortex and postconditioning might affect inflammatory reactions in the hippocampus or whe...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.02.005
更新日期:2011-04-12 00:00:00
abstract::Significant insights into the dynamics of neuronal populations have been gained in the olfactory system where rich spatio-temporal dynamics is observed during, and following, exposure to odours. It is now widely accepted that odour identity is represented in terms of stimulus-specific rate patterning observed in the c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.07.032
更新日期:2012-01-24 00:00:00