Binding of biosynthetic human insulin to erythrocytes of normal and insulin-dependent diabetic subjects: comparison with pork and human pancreatic insulin.

abstract：OBJECTIVE:To clarify the relationship between the angiotensin I-converting enzyme (ACE) gene polymorphism and diabetic micro- and macroangiopathy in patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:We examined 267 NIDDM patients with various stages of diabetic retinopathy, 61 ...

journal_title：Diabetes care

authors： Fujisawa T,Ikegami H,Shen GQ,Yamato E,Takekawa K,Nakagawa Y,Hamada Y,Ueda H,Rakugi H,Higaki J

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:To characterize metabolic effects of troglitazone in type 2 diabetic, obese, and lean subjects, and examine the effects of troglitazone 2-3 weeks after discontinuation. RESEARCH DESIGN AND METHODS:Nine type 2 diabetic, nine obese, and nine lean subjects underwent baseline metabolic studies including an 8-h m...

journal_title：Diabetes care

authors： Frias JP,Yu JG,Kruszynska YT,Olefsky JM

更新日期：2000-01-01 00:00:00

abstract：:In a 10-yr prospective population study 406 subjects who were 70 yr old received an oral glucose tolerance test. Of these subjects 169 were retested at 80. Three sets of diagnostic criteria were evaluated, of which the WHO criteria are recommended for screening studies in this age group. The prevalences of diabetes me...

journal_title：Diabetes care

authors： Agner E,Thorsteinsson B,Eriksen M

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:Cost-effectiveness analyses have reported that intensive glucose control is not cost-effective in older patients with new-onset diabetes. However, these analyses have had limited data on patient preferences concerning diabetic health states. We examined how the cost- effectiveness of intensive glucose control...

journal_title：Diabetes care

authors： Huang ES,Shook M,Jin L,Chin MH,Meltzer DO

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate alcohol consumption in relation to the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS:The study population consisted of 22778 twins of the Finnish Twin Cohort. This cohort was compiled in 1975 and includes all same-sexed twins born in Finland before 1958. I...

journal_title：Diabetes care

authors： Carlsson S,Hammar N,Grill V,Kaprio J

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to assess the efficacy and safety of our newly developed nasal glucagon-like peptide-1 (GLP-1) compound and injector. RESEARCH DESIGN AND METHODS:Twenty-six patients with type 2 diabetes were enrolled in this double-blind placebo-controlled study. The nasal compound containing 1.2 mg of huma...

journal_title：Diabetes care

authors： Ueno H,Mizuta M,Shiiya T,Tsuchimochi W,Noma K,Nakashima N,Fujihara M,Nakazato M

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Recipients of solid organ transplants have an increased risk of developing certain types of malignancies as compared with the general population. The majority of the literature has reported on neoplasms in kidney and heart transplant recipients. RESEARCH DESIGN AND METHODS:We describe 9 neoplasms occurring i...

journal_title：Diabetes care

authors： Martinenghi S,Dell'Antonio G,Secchi A,Di Carlo V,Pozza G

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To describe the relative contributions of neurological and vascular abnormalities to the overall risk of diabetic foot ulceration. RESEARCH DESIGN AND METHODS:A case-control study of diabetic veterans from the Seattle Veterans Affairs Medical Center was conducted using data collected from 46 patients with di...

journal_title：Diabetes care

authors： McNeely MJ,Boyko EJ,Ahroni JH,Stensel VL,Reiber GE,Smith DG,Pecoraro RF

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:Dietary fiber has recently received recognition for reducing the risk of developing diabetes and heart disease. The implication is that it may have therapeutic benefit in prediabetic metabolic conditions. To test this hypothesis, we investigated the effect of supplementing a high-carbohydrate diet with fiber ...

journal_title：Diabetes care

authors： Vuksan V,Sievenpiper JL,Owen R,Swilley JA,Spadafora P,Jenkins DJ,Vidgen E,Brighenti F,Josse RG,Leiter LA,Xu Z,Novokmet R

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence and clinical associations of impaired awareness of hypoglycemia in a population-based sample of children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS:A validated questionnaire was administered to 656 patients with type 1 diabetes over a 6-month period to deter...

journal_title：Diabetes care

authors： Ly TT,Gallego PH,Davis EA,Jones TW

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare measurements of glucose obtained via iontophoretic extraction with the GlucoWatch automatic glucose biographer (Cygnus, Inc., Redwood City, CA) with capillary blood glucose values that were determined 1) in a controlled outpatient clinic setting and 2) in a home settin...

journal_title：Diabetes care

authors： Garg SK,Potts RO,Ackerman NR,Fermi SJ,Tamada JA,Chase HP

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Impaired awareness of hypoglycemia (IAH) and recurrent severe hypoglycemia (RSH) remain problematic for people with type 1 diabetes (T1D), despite major therapeutic advances. We explored beliefs around hypo- and hyperglycemia in adults with T1D with, and without, IAH and RSH. RESEARCH DESIGN AND METHODS:A cr...

journal_title：Diabetes care

authors： Cook AJ,DuBose SN,Foster N,Smith EL,Wu M,Margiotta G,Rickels MR,Speight J,de Zoysa N,Amiel SA

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of the insertion/deletion polymorphism of the ACE gene on the progression of early diabetic glomerulopathy in patients with and without antihypertensive treatment (AHT). RESEARCH DESIGN AND METHODS:There were 30 microalbuminuric patients with >5 years of type 1 diabetes who had r...

journal_title：Diabetes care

authors： Rudberg S,Rasmussen LM,Bangstad HJ,Osterby R

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:Elevated heart rate has been predictive of cardiovascular disease and has been proposed as a global index of the autonomic nervous system influence on the heart. Hyperinsulinism has been shown to trigger sympathetic activity experimentally; however, the clinical and epidemiological data on the association of ...

journal_title：Diabetes care

authors： Festa A,D'Agostino R Jr,Hales CN,Mykkänen L,Haffner SM

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:Neonatal diabetes is a heterogeneous group of disorders with diabetes manifestation in the first 6 months of life. The most common etiology in permanent neonatal diabetes is mutations of the ATP-sensitive K(+) channel subunits; in transient neonatal diabetes, chromosome 6q24 abnormalities are the most common ...

journal_title：Diabetes care

authors： Staník J,Lethby M,Flanagan SE,Gasperíková D,Milosovicová B,Lever M,Bullman H,Zubcevic L,Hattersley AT,Ellard S,Ashcroft FM,Klimes I

更新日期：2008-09-01 00:00:00

abstract：:In a patient with hyperthyroidism and newly diagnosed insulin-dependent diabetes mellitus (IDDM), insulin action and clearance were studied before the initiation of antithyroid treatment and at 3-mo intervals for 1 yr thereafter. The sequential euglycemic clamp technique (5 mM) was used with insulin infusion rates of ...

journal_title：Diabetes care

authors： Nijs HG,Radder JK,Frölich M,Krans HM

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:The objective was to examine prospectively the association between low testosterone and sex hormone-binding globulin (SHBG) levels and the subsequent development of type 2 diabetes in men. RESEARCH DESIGN AND METHODS:Analyses were conducted on the cohort of the Massachusetts Male Aging Study, a population-ba...

journal_title：Diabetes care

authors： Stellato RK,Feldman HA,Hamdy O,Horton ES,McKinlay JB

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To determine the value of measuring serum triglyceride (TG) levels early in pregnancy for predicting late-gestation glucose tolerance and neonatal birth weight ratio (BWR) (birth weight corrected for gestational age). RESEARCH DESIGN AND METHODS:The relationships between morning nonfasting TG measured early ...

journal_title：Diabetes care

authors： Nolan CJ,Riley SF,Sheedy MT,Walstab JE,Beischer NA

更新日期：1995-12-01 00:00:00

abstract：:OBJECTIVE To examine the use of mammography and Papanicolaou (Pap) smear among women with diabetes and to identify predictors of adherence to these tests. RESEARCH DESIGN AND METHODS We analyzed data of a nationally representative sample of Spanish women. Diabetes status was self-reported. Screenings were assessed ask...

journal_title：Diabetes care

authors： Jiménez-Garcia R,Hernandez-Barrera V,Carrasco-Garrido P,Gil A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of treatment with the glucagon-like peptide 1 receptor agonist exenatide on weight loss and metabolic parameters in obese nondiabetic women. RESEARCH DESIGN AND METHODS:Forty-one obese women (aged 48 ± 11 years and BMI 33.1 ± 4.1 kg/m(2)) participated in a 35-week randomized, double...

journal_title：Diabetes care

authors： Dushay J,Gao C,Gopalakrishnan GS,Crawley M,Mitten EK,Wilker E,Mullington J,Maratos-Flier E

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To implement an educational program in 10 Latin American countries and to evaluate its effect on the clinical, biochemical, and therapeutic aspects as well as the economic cost of diabetes. RESEARCH DESIGN AND METHODS:Educators from each participating country were previously trained to implement the educatio...

journal_title：Diabetes care

authors： Gagliardino JJ,Etchegoyen G,PENDID-LA Research Group.

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various strata. RESEARCH DESIGN AND METHODS:Men from the Health Professionals Follow-Up Study, who were i...

journal_title：Diabetes care

authors： de Koning L,Chiuve SE,Fung TT,Willett WC,Rimm EB,Hu FB

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To examine patients' views of the acceptability of and satisfaction with telephone care center support provided to improve blood glucose control in type 2 diabetes. RESEARCH DESIGN AND METHODS:The Pro-Active Call-Center Treatment Support (PACCTS) Trial randomized patients from 47 general practices in a depri...

journal_title：Diabetes care

authors： Long AF,Gambling T,Young RJ,Taylor J,Mason JM,PACCTS Team.

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:Previous studies have provided inconclusive results on the role of uric acid (UA) in risk prediction. Here we aimed to improve the power and precision of the predictive value of UA for the risk of decline in kidney function, cardiovascular events (CVEs), and mortality in patients with type 1 diabetes (T1D). ...

journal_title：Diabetes care

authors： Pilemann-Lyberg S,Hansen TW,Tofte N,Winther SA,Theilade S,Ahluwalia TS,Rossing P

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Of patients who are prescribed metformin, 10-30% have evidence of reduced vitamin B12 absorption. B12-intrinsic factor complex uptake by ileal cell surface receptors is known to be a process dependent on calcium availability Metformin affects calcium-dependent membrane action. The objective of this study was ...

journal_title：Diabetes care

authors： Bauman WA,Shaw S,Jayatilleke E,Spungen AM,Herbert V

更新日期：2000-09-01 00:00:00

abstract：:Insulin resistance is the cornerstone for the development of non-insulin-dependent diabetes mellitus (NIDDM). Free fatty acids (FFAs) cause insulin resistance in muscle and liver and increase hepatic gluconeogenesis and lipoprotein production and perhaps decrease hepatic clearance of insulin. It is suggested that the ...

journal_title：Diabetes care

authors： Björntorp P

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:In a previous study, we found observational evidence of improvement in beta-cell function when rosiglitazone was added to a failing oral antihyperglycemic regimen consisting of sulfonylureas and metformin. To confirm our previous observations, we designed and performed a prospective, randomized, and controlle...

journal_title：Diabetes care

authors： Ovalle F,Bell DS

更新日期：2004-11-01 00:00:00

abstract：:OBJECTIVE The American Diabetes Association advocates insulin regimens for youth with type 1 diabetes that involve adjusting insulin dose based on carbohydrate intake and blood glucose level. Implementing these regimens requires knowledge about carbohydrate content of foods and subsequent calculations of insulin dose,...

journal_title：Diabetes care

authors： Koontz MB,Cuttler L,Palmert MR,O'Riordan M,Borawski EA,McConnell J,Kern EO

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To determine whether increasing doses (amounts) of beta-glucan present in an extruded breakfast cereal affect the glycemic and insulinemic responses in eight NIDDM subjects, compared with the same responses after a continental breakfast (bread, milk, cheese, ham). RESEARCH DESIGN AND METHODS:Breakfast cereal...

journal_title：Diabetes care

authors： Tappy L,Gügolz E,Würsch P

更新日期：1996-08-01 00:00:00