Abstract:
:I devised a new technique using a thermal wedge resection at the time of keratoplasty to reduce excessive amounts of corneal astigmatism. Surface cautery was used to draw this thermal wedge of corneal tissue into the area to be trephined, and removed at surgery from the patient's cornea. The final result was the same as combining a surgical tissue wedge resection with keratoplasty. This new technique has resulted in reduction of the astigmatic error by as much as 8.5 diopters.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Hatch JLdoi
10.1016/s0002-9394(14)74844-5subject
Has Abstractpub_date
1980-08-01 00:00:00pages
137-41issue
2eissn
0002-9394issn
1879-1891pii
S0002-9394(14)74844-5journal_volume
90pub_type
杂志文章abstract:PURPOSE:To evaluate multifocal electroretinography (mfERG) as a screening test for detecting hydroxychloroquine and chloroquine toxicity. DESIGN:Diagnostic accuracy study. METHODS:Patients referred to the University of Ottawa for hydroxychloroquine or chloroquine retinopathy screening during 2011-2014 underwent 10-2 ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.04.025
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:To report color vision abnormalities associated with diabetic retinopathy. METHODS:Color vision function was measured at baseline in 2,701 patients enrolled in the Early Treatment Diabetic Retinopathy Study, a randomized trial investigating photocoagulation and aspirin in the treatment of diabetic retinopathy....
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(99)00227-5
更新日期:1999-11-01 00:00:00
abstract::A retrospective study of 23 conjunctival melanomas using the Clark classification revealed that the three most common forms of melanoma described in the skin--lentigo maligna melanoma (Hutchinson's freckle with melanoma), superficial spreading melanoma, and nodular melanoma--can be recognized in the conjunctiva. As in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90487-6
更新日期:1976-09-01 00:00:00
abstract:OBJECTIVE:To determine whether parapapillary choroidal microvasculature (PPCMv) density as measured by optical coherence tomography angiography differs between pseudoexfoliation syndrome (PXS) and pseudoexfoliation glaucoma (PXG). DESIGN:Cross-sectional study. METHODS:One hundred ninety-two eyes of 120 subjects from ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.002
更新日期:2020-12-10 00:00:00
abstract::We studied 300 visual fields of 153 consecutive patients who had glaucoma or increased intraocular pressures. All the visual fields were plotted with the same technique on a Goldmann perimeter. Crowding of the peripheral nasal isopters was said to be present when the nasal isopter, outlined with the peripheral thresho...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(82)90183-0
更新日期:1982-07-01 00:00:00
abstract::T-cell and B-cell lymphocyte subpopulations, monocytes, granulocytes, and immunoglobulin receptors were measured with monoclonal antibodies and flow cytometric techniques in the peripheral blood of 266 patients with posterior uveal melanoma before therapy. Statistically significant differences were found in T-helper/i...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90587-8
更新日期:1986-02-15 00:00:00
abstract:PURPOSE:To perform 11- and 2-year health care sector (ophthalmic) and societal cost perspective reference case, cost-utility analyses comparing bevacizumab, ranibizumab, and aflibercept monotherapies for neovascular age-related macular degeneration (NVAMD). DESIGN:Cost-utility analysis. METHODS:The authors performed ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.029
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To determine whether alterations of p53, a tumor suppressor gene, were present in uveal melanoma, and to characterize further the nature of those changes. METHODS:Immunohistochemical analysis with a monoclonal antibody was used to determine whether alterations of p53 were present in 35 enucleated archival uvea...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75431-5
更新日期:1996-05-01 00:00:00
abstract:PURPOSE:To determine the effects of a second fluocinolone implant inserted in eyes with uveitis in which recurrent inflammation developed after the original implant was placed. DESIGN:Prospective, interventional trial. METHODS:Study subjects comprised all consecutive patients with noninfectious posterior uveitis who ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.11.008
更新日期:2008-04-01 00:00:00
abstract::Of two patients with type 5 hyperlipoproteinemia, one exhibited lipemia retinalis with multiple retinal hemorrhages and intraretinal lipid extravasations. Postmortem examination showed hemorrhages in the inner retinal layers and lipid deposits largely in the outer plexiform layer. Lipid within the walls of the retinal...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90661-9
更新日期:1976-07-01 00:00:00
abstract:PURPOSE:To analyze the indocyanine green angiographic findings of drusen in the early stages of age-related macular degeneration. METHODS:Sixty-nine eyes of 53 consecutive patients with drusen but without exudative complications of age-related macular degeneration were studied. Drusen were classified into four groups:...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70826-8
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:Diseases that involve retinal or choroidal vascular endothelial cells are leading causes of vision loss: age-related macular degeneration, retinal ischemic vasculopathies, and noninfectious posterior uveitis. Proteins differentially expressed by these endothelial cell populations are potential drug targets. We ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.03.020
更新日期:2018-09-01 00:00:00
abstract::Glycogen, adenosine triphosphate, and hydration were measured in rabbit corneal epithelium to determine whether the corneal epithelium glycogen decrease, increase in epithelial hydration, and decrease in epithelial adenosine triphosphate stores, seen as a result of contact lens wear, were secondary only to anoxia or m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90884-3
更新日期:1975-07-01 00:00:00
abstract:PURPOSE:To assess the clinical outcomes of currently used refractive surgery procedures performed in 2015. DESIGN:Prospective, multicenter cohort study. METHODS:This prospective study included 15 011 eyes of 7622 consecutive patients who underwent laser in situ keratomileusis (LASIK), surface ablation, refractive len...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2016.12.009
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:To report a case of extensive cephalic and basilic venous thrombosis after fluorescein angiography. DESIGN:Interventional case report. METHODS:A 38-year-old Chinese male presented with blurring of vision in his left eye. Clinical examination revealed central serous retinopathy, and a routine fluorescein angio...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.10.058
更新日期:2005-05-01 00:00:00
abstract::We evaluated the reliability of optic disk area and disk rim area measurements obtained with the Humphrey Retinal Analyzer from ten repeat fundus images each of one eye of ten normal subjects and ten subjects with increased intraocular pressure. Variability of rim and disk areas was not significantly different between...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73309-4
更新日期:1989-10-15 00:00:00
abstract:PURPOSE:To assess the prevalence of refractive error and vision impairment in school age children in the terai area of the Mechi zone in Eastern Nepal. METHODS:Random selection of village-based clusters was used to identify a sample of children 5 to 15 years of age. Children in the 25 selected clusters were enumerated...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(99)00453-5
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:To report bilateral optic disk edema and blindness as the unusual initial presentation of acute lymphocytic leukemia (ALL) in an adult. METHODS:A 19-year-old man presented with a history of headaches, back pain, and 10 days of worsening vision that progressed to blindness. Ocular examination revealed light per...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01465-4
更新日期:2002-07-01 00:00:00
abstract:PURPOSE:Intraindividual comparison of tilt and decentration of three-piece foldable intraocular lenses (IOLs) with 6-mm optics and different edge design and material. DESIGN:Prospective randomized study. METHODS:Twenty-five patients with senile cataract (group I) received a foldable silicone, sharp optic edge IOL in ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2005.07.026
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:To determine whether spectral-domain optical coherence tomography (SD-OCT) disorganization of the retinal inner layers (DRIL) is predictive of best-corrected visual acuity (BCVA) in retinal vein occlusion macular edema (RVO-ME). DESIGN:Retrospective cohort study. METHODS:Setting: Two tertiary centers. PATIEN...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2017.08.005
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:The purpose of this study was to compare the perioperative parameters of quadrant, sextant, and grid lens fragmentation patterns in femtosecond laser-assisted cataract surgery (FLACS). DESIGN:Prospective randomized clinical trial. METHODS:Setting: Eye Center of the Second Affiliated Hospital, School of Medici...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2019.12.017
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To determine the duration of positive urine for benzoylecgonine, the major metabolite excreted in the urine, after topical ophthalmic administration of cocaine as one would perform for testing the presence of Horner syndrome. METHODS:Two drops of cocaine 10% were applied to each eye of 50 normal subjects. Urin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00945-4
更新日期:2001-06-01 00:00:00
abstract:PURPOSE:To identify baseline structural parameters that predict the progression of visual field (VF) loss in patients with open-angle glaucoma. DESIGN:Multicenter cohort study. METHODS:Participants from the Advanced Imaging for Glaucoma (AIG) study were enrolled and followed up. VF progression is defined as either a ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.ajo.2016.09.015
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:To describe the use of anterior segment optical coherence tomography (AS-OCT) to clarify the position and patency of aqueous shunt devices in the anterior chamber of eyes where corneal edema or tube position does not permit a satisfactory view. DESIGN:Noncomparative observational case series. METHODS:Four cas...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.02.023
更新日期:2007-06-01 00:00:00
abstract::Schirmer tests showed decreased tearing (less than 15 mm of wetting) in 32 of 54 eyes (59%) of a representative group of patients with corneal xerophthalmia but in only four of 60 eyes (7%) of age-, sex-, and neighborhood-matched controls (P less than .001). The occurrence of decreased tearing was directly related to ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(82)90703-6
更新日期:1982-01-01 00:00:00
abstract:PURPOSE:To correlate the histologic and clinical classification of type 1 (subretinal pigment epithelium) and type 2 (subsensory retina) choroidal neovascularization. METHODS:Ten eyes of 10 patients with surgically excised choroidal neovascularization that were routinely processed and could be histologically classifie...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00145-7
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:To assess the role of muscular degeneration, we evaluated the correlation between ptosis severity and levator muscle function. DESIGN:Retrospective cohort study. METHODS:The medical records of 136 patients (53 men and 83 women; mean age, 67 years) with acquired blepharoptosis were reviewed for levator functio...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.02.002
更新日期:2008-06-01 00:00:00
abstract::We studied 1,000 eyes of 500 subjects in an attempt to discover a relationship between lattice and snail track degenerations of the peripheral retina. Because of the clinical similarities between these two degeneration lesions, we suggest that snail track degeneration is either a variant of or an early stage of lattic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90639-5
更新日期:1981-10-01 00:00:00
abstract:PURPOSE:To compare race-related differences in estimated rate of change of Bruch's membrane opening-minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer thickness (RNFLT) in healthy, glaucoma suspect, and glaucoma eyes of individuals of European (ED) and African descent (AD). DESIGN:Prospective co...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.08.050
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To determine whether patients can guess their intraocular pressure (IOP). DESIGN:Patient survey. METHODS:We asked consecutive patients to guess their IOP and then indicate the IOP and the symptoms that allowed them to guess. RESULTS:Of 132 patients, 22 (17%) believed they could guess their IOP, usually based...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/S0002-9394(03)00861-4
更新日期:2004-02-01 00:00:00