Abstract:
:Two patients with progressive hairy cell leukemia following splenectomy were treated with low-dose daily chlorambucil. Both had an objective hematologic response as determined by a return to normal hematocrit and platelet count. This was also reflected in the mononuclear cell fraction by the normalization of cholesterol content, cholesterol/phospholipid ratio, and the lymphocyte subpopulations. This article confirms previous reports on the efficacy of chlorambucil in this setting and describes some morphological, and biochemical concomitant events.
journal_name
Bloodjournal_title
Bloodauthors
Krigel R,Liebes LF,Pelle E,Silber Rsubject
Has Abstractpub_date
1982-07-01 00:00:00pages
272-5issue
1eissn
0006-4971issn
1528-0020journal_volume
60pub_type
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