Abstract:
:Thirty seven children with acute lymphoblastic leukemia (All) treated according to 2 different protocols were randomized after remission induction to receive levamisole or not during remission maintenance continuous or intermittent polychemotherapy. The usefulness of levamisole in prolonged remission and survival time by the actuarial analysis were studied. At 36th month 45% patients treated with levamisole, and 30% without levamisole remained in complete remission. The increase of E+ lymphocyte and total lymphocyte count in the 18th week of chemoimmunotherapy, and their decrease in 27th week of the treatment were demonstrated. The granulocyte phagocytic activity increased in the 27th week of treatment. The results obtained suggest that levamisole therapy stimulates T lymphocyte production and phagocytic activity and enables the appropriate cytostatic treatment.
journal_name
Arch Immunol Ther Exp (Warsz)journal_title
Archivum immunologiae et therapiae experimentalisauthors
Bogusławska-Jaworska J,Raus Zsubject
Has Abstractpub_date
1981-01-01 00:00:00pages
719-23issue
6eissn
0004-069Xissn
1661-4917journal_volume
29pub_type
临床试验,杂志文章,随机对照试验abstract::The dry thermal glycation method was used to conjugate D-glucose and D-fructose with bovine serum albumin. Reactions were conducted at 50-104 degrees C for 30 min. Depending on temperature, different levels of substitution were achieved. In the case of D-glucose, average substitution levels of up to 53 mol glucose/mol...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::The comparison of electrophoretic protein patterns and concentrations of the G, A and M immunoglobulins before initiation of oral IFN-alpha therapy of viral hepatitis and after 2 weeks of treatment allow to predict patient's response. Patient who after 2 weeks of treatment with ultra-low orally administered IFN-alpha ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::The intraventricular administration of histamine in a dose of 500 microgram, and two histamine H2-receptor agonists i.e. 50-250 microgram of dimaprit and 100 microgram of 4-methylhistamine decreased GABA level after 30 min (by approximately 20%) in the hypothalamus, but not in the striatum of the rat brain. The level ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The study group consisted of 13 patients, including 5 in complete remission and 8 in incomplete hematologic remission. Six patients had a pause in therapy, and the remaining ones were continuing maintenance therapy. In all cases production of IgG, IgA and IgM immunoglobulins was maintained. Response of lymphocytes to ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Nicotinic acetylcholine receptors (nAChRs) are membrane ligand-gated cation channels whose activation is triggered by the binding of the endogenous neurotransmitter acetylcholine or other biologic compounds including nicotine. Their roles in synaptic transmission in the central and peripheral nervous system as well as...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:10.1007/s00005-013-0266-6
更新日期:2014-04-01 00:00:00
abstract::Molecular chaperones were considered to be intracellular, but there is increasing evidence demonstrating their cytoprotective and immune modulator properties outside the cell. The major extracellular chaperone (Hsp70) was also found in saliva, indicating a possible effect of Hsp70 on mucosal surfaces. Here we summariz...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:10.1007/s00005-007-0012-z
更新日期:2007-03-01 00:00:00
abstract::Mycobacterium tuberculosis (Mtb) survives and proliferates within the main cells of the innate immune system, macrophages. The goal of our study was to investigate the immunostimulatory effects of 13-cis retinoic acid (RA) and chicoric acid (CA) in human U937 macrophages against H37Ra Mtb infection by evaluating its p...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:10.1007/s00005-018-0511-0
更新日期:2018-10-01 00:00:00
abstract::Human cathelicidin, LL-37, is small antimicrobial peptide, which reveals also some immunomodulatory and proangiogenic properties and, therefore, may promote wound healing. The expression of LL-37 is controlled by various factors, including vitamin D. Thus, any disturbances in vitamin D level may influence LL-37 produc...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:10.1007/s00005-016-0423-9
更新日期:2017-10-01 00:00:00
abstract::Sphingosine 1-phosphate (S1P) has been shown to be a bioactive lipid mediator intimately involved in mediating a variety of immunological processes. In particular, S1P regulates lymphocyte cell trafficking between the lymphatic system and the blood. The lysophospholipid signals mainly through five related G protein-co...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:10.1007/s00005-006-0028-9
更新日期:2006-07-01 00:00:00
abstract::The aim of this study was to analyze association between HLA class I antigens and sarcoidosis in Poland. HLA-A, B, C antigens in a group of 100 patients suffering from sarcoidosis and in a group of 100 healthy blood donors were determined. Histocompatibility typing was performed by the NIH method using commercially av...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::The immunogenicity of trypsinized and radiation-sterilized bovine fascia enriched with pulverized calf cartilage was tested by the regional lymph node blastic cell reaction. The influence of these grafts on the adjacent tissue and on regeneration processes was examined histologically. After transplantation into mice t...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::A simple classification of cytokines is presented. It is based on voluminous information available from published papers of many outstanding researchers of the cytokines and their receptors and/or summarized by experts in this field. The cytokines are divided into 7 families according to their receptor code. Such arra...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::Pharmacological activity of 6 newly synthetized water-soluble derivatives of barbiturylo propanosulfonic acids, was evaluated. The compounds were obtained under the conditions of the Ritter reaction. The experiments were performed with the aim to determine the anti-inflammatory and immunotropic activities as well as t...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::It was demonstrated that human, recombinant Il-1 significantly inhibited formation of autologous rosettes by thymocytes. In addition, Il-1 increased the percentage of thymocytes resistant to hydrocortisone. Il-2 was not active in both tests. A new method of determination of Il-1 activity, based on the inhibition of th...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Mast cells are important effector cells in allergic inflammatory reactions. The aggregation of the high-affinity IgE receptor (FcepsilonRI) on the surface of mast cells initiates a complex cascade of signaling events that ultimately leads to the release of various mediators involved in allergic inflammation and anaphy...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:10.1007/s00005-008-0041-2
更新日期:2008-11-01 00:00:00
abstract::Adjuvant-induced arthritis in rats is a chronic inflammatory disease, widely used as an animal model for rheumatoid arthritis. In our study the effect of various fractions of dialyzable leukocyte extract (DLE): DLE I-molecular weight below 10 kDa (commercial preparation), DLE II-molecular weight below 5 kDa (suppresso...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The ability of retinoic acid to inhibit the growth of three human melanoma cell lines (MEW18, MEW22, MEW81) was studied in culture. The exposure of the cell lines to different concentrations of RA resulted in an inhibition of the cell growth, dependent on the quantity of RA in the medium. Effects on cell growth of MEW...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Eleven mycoplasma strains were isolated from the semen of 24 stallions. Eight of these strains were identified as Mycoplasma equigenitalium. Three strains which hydrolized arginine could not be identified. The growth inhibition test with immune sera against M. arginini and M. equirhinis was negative. Antibiotic sensit...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Our studies on the syngeneic immunization with normal cells did not confirm the possibility of induction of alloreactive cytotoxic antibodies in this way. We were not able to induce any antibodies after syngeneic immunizations within BALB/c and BALB/cfC3H strains of mice. Anti-H-2 cytotoxic antibodies were raised by s...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Decalcified rat bone matrix or sequentially treated rat bone gelatin, as well as dog transitional epithelium when implanted intramuscularly in mice induce cartilage, bone and bone marrow formation. Heterotopic bone induction is markedly reduced or abolished when animals are irradiated prior to implantation of decalcif...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Diabetes and cancer are diseases which take the size of an epidemic spread across the globe. Those diseases are influenced by many factors, both genetic and environmental. Precise knowledge of the complex relationships and interactions between these two conditions is of great importance for their prevention and treatm...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章,评审
doi:10.1007/s00005-011-0119-0
更新日期:2011-06-01 00:00:00
abstract::Monoclonal antibody 791T/36, directed against surface antigen on the human osteosarcoma cell line (791T), and cross-reacting with surface antigen p72 expressed on activated (PHA, MLR) human peripheral blood mononuclear cells (PBM), was used in analysis of p72 antigen in vitro. Using FACS-IV system and fluorescence mic...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Increases in plasma kynurenic acid (KYNA) concentration relate to the severity of inflammation. The aim of this study was to analyse changes in plasma KYNA concentration and neutrophil/lymphocyte ratio (NLR) in cardiac surgery patients. Additionally, the effect of anaesthesia was analysed. Adult cardiac surgery patien...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:10.1007/s00005-014-0312-z
更新日期:2015-04-01 00:00:00
abstract::Extracts from Erodium cicutarium L. Herit were tested for antiviral and interferon inducing properties. Both water extract and methanol extract as well as its fractions were observed to exert antiviral effect in relation to myxoviruses, Herpes virus type 1, Vesicular stomatitis and vaccinia virus. None of these extrac...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Alzheimer's disease (AD) is the most common human progressive dementia linked, in its sporadic form, to a common polymorphism within a gene for apolipoprotein E (APOE) mapped to chromosome 19. Individuals with APOE 4 isoforms are more prone to develop sporadic from of AD than those who carry APOE 2 or APOE 3 alleles. ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Using a Technicon autoanalyzer method of Marsh 752 sera of patients, Rh-negative subjects in the initial stage of immunization with Rh-positive blood, and healthy blood donors were investigated. In 56 sera (8.7%) positive reactions with standard erythrocytes were found. In 21 of these cases (36%) specificity of antibo...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Sustained chronic inflammation induces activation of genes involved in cellular proliferation and apoptosis, thereby causing skeletal muscle degeneration. To investigate in vitro effects of isolated pentacyclic triterpenes from Eugenia punicifolia (Ep-CM) upon signaling pathways involved in the regulation of skeletal ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:10.1007/s00005-014-0291-0
更新日期:2014-12-01 00:00:00
abstract::Rabbit peripheral blood was tested for the ratio of T and B lymphocytes and for the number of plaque forming cells (PFC) on day 5 and 6 after immunization with sheep erythrocytes. Fever was induced by intravenous injection of lipopolysaccharide (LPS) of E. coli. At higher doses, suppressing the fever, only indomethaci...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Identification of cells producing ATL was carried out on suspensions of cells enriched with lymphocytes T, B and macrophages. The cells were isolated from the spleen of syphilitic rabbits and from their testes when the rabbits were infected intratesticularly. The isolation of lymphocytes and macrophages was performed ...
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The role of antibodies in immunity to intravenous infection with dysentery bacilli was studied in mice. Serum from animals immunized with a single dose of live dysentery bacilli obtained at a varying intervals of time after immunization transferred immunity to other mice infected with lethal doses of the same bacilli....
journal_title:Archivum immunologiae et therapiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00