Therapies and vaccines for emerging bacterial infections: learning from methicillin-resistant Staphylococcus aureus.

Abstract:

:Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging bacterial infection worldwide, and community-acquired MRSA (CA-MRSA) infection, which has increased dramatically in frequency in many areas, is of particular clinical and public health concern. CA-MRSA outbreaks and severe infections have been reported more frequently in children, often manifesting in one of two distinct clinical syndromes, furunculosis or necrotizing pneumonia. This article outlines the molecular biology of MRSA, how molecular biology has contributed to the understanding of MRSA infections, current therapy and prevention of MRSA, and the prospects for a vaccine against S aureus.

journal_name

Pediatr Clin North Am

authors

John CC,Schreiber JR

doi

10.1016/j.pcl.2006.05.004

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

699-713

issue

4

eissn

0031-3955

issn

1557-8240

pii

S0031-3955(06)00067-8

journal_volume

53

pub_type

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