The Noonan syndrome.

Abstract:

:Twenty-one patients with Noonan syndrome are presented. Telecanthus low-set ears, epicanthus and facial asymmetry were the commoner facial stigmata. Pterygium colli, pectus excavatum-carinatum and mild physical and mental retardation were also common features. Pulmonary stenosis and patent ductus arteriosus were the most frequent cardiac anomalies. Wide QRS, left axis deviation, giant Q waves and a negative pattern in V6 were useful electrocardiographic signs. We speculate that the Noonan syndrome could be considered as a branchial arch development syndrome.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Sanchez-Cascos A

doi

10.1093/oxfordjournals.eurheartj.a061452

subject

Has Abstract

pub_date

1983-04-01 00:00:00

pages

223-9

issue

4

eissn

0195-668X

issn

1522-9645

journal_volume

4

pub_type

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