Effects of estrogen and related agents upon methamphetamine-induced neurotoxicity within an impaired nigrostriatal dopaminergic system of ovariectomized mice.

abstract：:A portion of medial basal hypothalamus containing the supraoptic nuclei with the neurohypophysis attached was organ cultured. Hypothalamus and neurohypophysis were maintained in separate compartments, and the intact infundibular stalk passed through a hole in a fluid-tight barrier which separated the two compartments....

journal_title：Neuroendocrinology

authors： Gregg CM

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Synaptic plasticity is the neuronal capacity to modify the function and structure of dendritic spines (DS) in response to neuromodulators. Sex steroids, particularly 17β-estradiol (E2) and progesterone (P4), are key regulators in the control of DS formation through multiprotein complexes including WAVE1 prot...

journal_title：Neuroendocrinology

authors： Uzair ID,Flamini MI,Sanchez AM

更新日期：2020-01-01 00:00:00

abstract：:To study the role of the hypothalamus in the regulation of growth hormone (GH) synthesis, the rate of amino acid incorporation into GH in vitro was examined in rats with anterolateral deafferentation of the medial basal hypothalamus. Amino acid incorporation into GH (GH synthesis) decreased significantly 7 days after ...

journal_title：Neuroendocrinology

authors： Ieiri T,Ishikawa K,Suzuki M,Shimoda S

更新日期：1988-05-01 00:00:00

abstract：:Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are a rare, heterogeneous group of tumors that originate from the endocrine system of the gastrointestinal tract and pancreas. GEP-NEN are subdivided according to their differentiation into well differentiated gastroenteropancreatic neuroendocrine tumors (NET...

journal_title：Neuroendocrinology

authors： Detjen K,Hammerich L,Özdirik B,Demir M,Wiedenmann B,Tacke F,Jann H,Roderburg C

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:The appetite-stimulating hormone ghrelin is a fundamental regulator of human energy metabolism. A series of studies support the notion that long-term appetite and weight regulation may be already programmed in early life and it could be demonstrated that the intrauterine environment affects the ghrelin syste...

journal_title：Neuroendocrinology

authors： Paslakis G,Buchmann AF,Westphal S,Banaschewski T,Hohm E,Zimmermann US,Laucht M,Deuschle M

更新日期：2014-01-01 00:00:00

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：:We have investigated the variations in growth hormone (GH) and somatostatin (SOM) mRNAs in adult, middle-aged and aging rats of both sexes using quantitative in situ hybridization. cDNA probes complementary to GH mRNA and SOM mRNA were used on fixed pituitary and hypothalamic sections, respectively. A clear sexual dim...

journal_title：Neuroendocrinology

authors： Martinoli MG,Ouellet J,Rhéaume E,Pelletier G

更新日期：1991-12-01 00:00:00

abstract：:The effect of amphetamine (AMPH) on plasma corticosterone was studied in the conscious, unstressed rat. AMPH (0.5-5.0 mg/kg) produced a dose-dependent increase in plasma corticosterone. This rise in plasma corticosterone was not altered by the adrenergic blocking agents phenoxybenzamine or propranolol. In contrast, th...

journal_title：Neuroendocrinology

authors： Knych ET,Eisenberg RM

更新日期：1979-01-01 00:00:00

abstract：:In these three experiments, we investigated the effect of adrenalectomy and adrenal demedullation on the stress-induced impairment of long-term potentiation (LTP) in the rat hippocampal slice. In the first, adrenalectomy alone resulted in a significant reduction in LTP, while exposure to stress resulted in a further r...

journal_title：Neuroendocrinology

authors： Shors TJ,Levine S,Thompson RF

更新日期：1990-01-01 00:00:00

abstract：:Introduction Autophagic cell death in cancer cells can be mediated by inhibition of deacetylases. Although extensive studies have focused on the autophagic process in cancer, little is known about the role of autophagy in degrading cytosolic and nuclear components of pancreatic neuroendocrine neoplastic (pNEN) cells l...

journal_title：Neuroendocrinology

authors： Matrood S,de Prisco N,Wissniowski T,Wiese D,Jabari S,Griesmann H,Wanzel M,Stiewe T,Neureiter D,Klieser E,Mintziras I,Buchholz M,Bartsch DK,Gennarino V,Di Fazio P

更新日期：2020-10-27 00:00:00

abstract：:Immobilization of adult male rats resulted in concomitant, significant releases of prolactin (PRL) and oxytocin (OT). Naloxone (0.2 mg/kg, i.p.) administration 30 min prior to initiation of restraint resulted in a significant diminution of the PRL response to stress. On the other hand, a significant augmentation of OT...

journal_title：Neuroendocrinology

authors： Samson WK,McDonald JK,Lumpkin MD

更新日期：1985-01-01 00:00:00

abstract：:The orphanin-FQ/nociceptin (OFQ/N) receptor (previously, ORL1, LC132) has been shown to be coupled to an inwardly rectifying K+ conductance in several neuronal populations. Although OFQ/N receptor mRNA is densely expressed in the supraoptic nucleus (SON), little is known about its coupling to effector system(s). The p...

journal_title：Neuroendocrinology

authors： Slugg RM,Rønnekleiv OK,Grandy DK,Kelly MJ

更新日期：1999-05-01 00:00:00

abstract：:G-protein-coupled receptor 135 (GPCR135), a former orphan GPCR also known as SALPR, has recently been shown to be modulated by relaxin-3 (R3). In addition to GPCR135, R3 has been shown to be an agonist for GPCR142 (which is a pseudogene in the rat) and to activate LGR7, which is primarily the receptor for relaxin-1/2....

journal_title：Neuroendocrinology

authors： Sutton SW,Bonaventure P,Kuei C,Roland B,Chen J,Nepomuceno D,Lovenberg TW,Liu C

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The amygdala receives afferent sensory input and processes information related to hydromineral balance. Angiotensin acts on and through the amygdala to stimulate thirst and sodium appetite. In addition, different angiotensins seem to play a role in cognition and learning mechanisms by acting on and through t...

journal_title：Neuroendocrinology

authors： Staschewski J,Kulisch C,Albrecht D

更新日期：2011-01-01 00:00:00

abstract：:Neuroendocrine mechanisms governing growth hormone (GH) secretion are sensitive to nutritional status since the normal pulsatile pattern of GH release is disrupted during conditions of food deprivation or malnutrition. A reasonable hypothesis for this occurrence is the alteration of somatostatin and GH-releasing hormo...

journal_title：Neuroendocrinology

authors： Brogan RS,Fife SK,Conley LK,Giustina A,Wehrenberg WB

更新日期：1997-02-01 00:00:00

abstract：:The hypothesis was tested that corticotropin-releasing factor (CRF) is involved in the inhibition of gonadotropin secretion during chronic hyperprolactinemia. Two models of hyperprolactinemia were used, namely inoculation with the prolactin (PRL)-secreting tumor 7315b and implantation of isogenic pituitary glands. Gon...

journal_title：Neuroendocrinology

authors： Kooy A,de Greef WJ,Vreeburg JT,Hackeng WH,Ooms MP,Lamberts SW,Weber RF

更新日期：1990-03-01 00:00:00

abstract：:We have used excitatory amino acids as tools to elucidate changes in hypothalamic function associated with lactation, focusing on the regulation of luteinizing hormone (LH) and prolactin secretion. In these studies, we have compared the responsiveness to NMA (N-methyl-D,L-aspartate), an agonist for the N-methyl-D-aspa...

journal_title：Neuroendocrinology

authors： Abbud R,Smith MS

更新日期：1993-10-01 00:00:00

abstract：:In vivo single-unit extracellular recording was used to assess neuronal membrane sensitivity at the level of the midbrain central gray (MCG) to the iontophoresis of luteinizing hormone releasing hormone (LHRH) and beta-endorphin (beta-END). The percentage of change in firing rate was evaluated to determine the effect ...

journal_title：Neuroendocrinology

authors： Schiess MC,Dudley CA,Moss RL

更新日期：1987-06-01 00:00:00

abstract：:Pituitary transcription factor-1 (Pit-1 or GHF-1) is a transcription factor specific to the anterior pituitary and is involved in the expression and regulation of the growth hormone (GH), prolactin (PRL) and thyroid-stimulating hormone (TSH) beta-subunit genes. The expression of these three genes can be modulated by c...

journal_title：Neuroendocrinology

authors： González-Parra S,Chowen JA,García-Segura LM,Argente J

更新日期：1996-01-01 00:00:00

abstract：:In addition to its traditional role as a circulating vasoactive peptide, vasopressin (VP) has been shown to play significant roles in central cardiovascular processing. The recent description of VP receptors within the subfornical organ (SFO) has suggested this circumventricular organ (CVO) as a potential locus for fe...

journal_title：Neuroendocrinology

authors： Smith PM,Ferguson AV

更新日期：1997-08-01 00:00:00

abstract：:The present study was designed to investigate whether the vasoactive intestinal peptide (VIP) concentration in hypothalamic nuclei, dorsal raphe nucleus (DR) and pituitary lobes of lactating rats changes in physiological situations when prolactin (PRL) secretion is stimulated (suckling) or inhibited (pup separation). ...

journal_title：Neuroendocrinology

authors： Chiocchio SR,de las Nieves Parisi M,Vitale ML,Tramezzani JH

更新日期：1991-07-01 00:00:00

abstract：:Kisspeptin is a neuropeptide that signals via a Gαq-coupled receptor, GPR54, in gonadotropin-releasing hormone (GnRH) neurons and is essential for pubertal maturation and fertility. Kisspeptin depolarizes and excites GnRH neurons primarily through the activation of canonical transient receptor potential (TRPC) channel...

journal_title：Neuroendocrinology

authors： Rønnekleiv OK,Zhang C,Bosch MA,Kelly MJ

更新日期：2015-01-01 00:00:00

abstract：:Because of some indication that FSH secretion is less dependent than LH secretion on GnRH in vivo, we performed experiments to examine the effects of a GnRH antagonist (antag) on LH and FSH secretion. We first showed that pituitary cells superfused with GnRH showed a similar pattern of suppressed secretion of both LH ...

journal_title：Neuroendocrinology

authors： Grady RR,Shin L,Charlesworth MC,Cohen-Becker IR,Smith M,Rivier C,Rivier J,Vale W,Schwartz NB

更新日期：1985-03-01 00:00:00

abstract：:Experiments were carried out to increase the endogenous levels of TRH in brain and spinal cord. After 7 days of continuous oral ingestion of TRH analogs (D-pGlu-Leu-ProNH2, pGlu-Leu-Pro, pGlu-Pro-ProNH2, or pGlu-Leu-pyrrolidide), spinal cord and brain levels of TRH were elevated, whereas the content of TRH metabolite,...

journal_title：Neuroendocrinology

authors： Prasad C,Eloby-Childress S,Iriuchijima T,Wilber JF,Szirtes T,Kisfaludy L

更新日期：1989-02-01 00:00:00

abstract：:A number of neurochemical messengers have been shown to act directly on the melanotrope cells of the pars intermedia of Xenopus laevis to regulate alpha MSH secretion. In the present study the possibility that the melanotropes are also indirectly controlled has been examined. For this purpose, the characteristics of a...

journal_title：Neuroendocrinology

authors： de Koning HP,Jenks BG,Scheenen WJ,de Rijk EP,Caris RT,Roubos EW

更新日期：1991-07-01 00:00:00

abstract：:Phase relation between plasma corticosterone and locomotor activity rhythms was analyzed in individual rats with selective lesions of suprachiasmatic nuclei (SCN). SCN in Wistar male rats were selectively coagulated electrically and the extent of SCN destruction was examined histologically. Spontaneous locomotor activ...

journal_title：Neuroendocrinology

authors： Watanabe K,Hiroshige T

更新日期：1981-07-01 00:00:00

abstract：:Sexual differentiation of brain function is regulated by estrogen in the perinatal period of rodents. However, the role of the estrogen receptor subtypes ERα and ERβ is still in question. Accordingly, the effects of neonatal treatment with the ERα agonist propyl pyrazole triol (PPT) or the ERβ agonist diarylpropionitr...

journal_title：Neuroendocrinology

authors： Kanaya M,Yamanouchi K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Tryptophan is the precursor of serotonin and niacin (vitamin B3). The latter is critical for normal cellular metabolism. Tryptophan and niacin can be deficient in patients with serotonin-producing neuroendocrine tumors (NETs). Niacin deficiency may lead to severe symptoms including pellagra. In patients...

journal_title：Neuroendocrinology

authors： Bouma G,van Faassen M,Kats-Ugurlu G,de Vries EG,Kema IP,Walenkamp AM

更新日期：2016-01-01 00:00:00

abstract：:Interleukin-1 (IL-1) and glucocorticoid hormones represent two key mediators involved in the modulation of the neuroimmunoendocrine response to stress. IL-1 is a potent activator of the hypothalamic-pituitary-adrenal (HPA) axis in rodents. In the immune system, glucocorticoids modulate IL-1 production and a number of ...

journal_title：Neuroendocrinology

authors： Betancur C,Lledo A,Borrell J,Guaza C

更新日期：1994-02-01 00:00:00

abstract：:The purpose of this study was to determine the effect of rendering newborn male Sprague-Dawley rats hypothyroid with 131I on development of the hypothalamic-pituitary axis. Hormonal responses to thyrotropin-releasing hormone (TRH), haloperidol (H), and luteinizing hormone-releasing hormone (LHRH) were determined at 9,...

journal_title：Neuroendocrinology

authors： Sowers JR,Resch G,Walker S,Sollars E

更新日期：1980-05-01 00:00:00