Abstract:
:This review assessed the overall effectiveness of repeated treatments with botulinum toxin type A (BoNTA) across different conditions, as documented in the published literature. Forty-four original research articles reporting on 16 different conditions were identified that included data on the duration or efficacy of multiple treatments with BoNTA. All of the 44 studies found sustained or enhanced improvement in efficacy and/or duration over the follow-up period, which ranged from a few treatments to more than 10 years. Dosages did not change over time in 22 of the studies, increased in 4 studies, were not reported over time in 17 studies, and tended to increase then decrease in one study. Seven studies reported a statistically significant increase in the efficacy or duration of BoNTA over time. Results suggest that continued benefit with repeated BoNTA treatment is widely reported in the literature.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Gordon MF,Barron Rdoi
10.1097/01.smj.0000220888.88722.absubject
Has Abstractpub_date
2006-08-01 00:00:00pages
853-61issue
8eissn
0038-4348issn
1541-8243journal_volume
99pub_type
杂志文章,评审abstract::A 42-year-old man had nausea, vomiting, periumbilical pain, tenesmus, and diarrhea shortly after eating seafood. Stool microscopy showed "beaver bodies," or Psorospermium haeckelii, a nonpathogenic algal organism often confused with enteric pathogens and commonly found in the excrement of persons consuming crayfish. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:Ventilator-associated pneumonia (VAP) is one of the most frequent infections in intensive care units (ICUs), and nearly 50% of patients with VAP develop septic shock. Septic shock is an independent predictor for mortality in these patients. OBJECTIVE:To investigate the predictors for septic shock in VAP pat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181827891
更新日期:2008-12-01 00:00:00
abstract::We describe a 47-year-old man with shoulder pain, multiple bony lesions, and a 1-cm lesion in the spleen. T-1 facetectomy revealed a poorly differentiated malignant neoplasm. Several months after chemotherapy, multiple splenic lesions were found by computed tomography and liver-spleen scan. A splenectomy showed a mali...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199508000-00020
更新日期:1995-08-01 00:00:00
abstract::We studied 67 patients who had operation for perforated peptic ulcer. Operative treatment included plication with omentum (Graham closure) in 27 patients, vagotomy and pyloroplasty in 32 patients, or vagotomy and antrectomy in eight patients, depending on antecedent ulcer history, degree of contamination, and general ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198310000-00006
更新日期:1983-10-01 00:00:00
abstract::Most nonendocrine pancreatic neoplasms are adenocarcinomas of ductal cell or acinar origin. Primary carcinomas of the pancreas with squamous differentiation are rare enough to warrant a search for other primary tumors. In the past few decades, well-documented individual reports and large series reviews support the vie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::This report describes a cocaine user who presented with polymorphonuclear pleocytosis in cerebrospinal fluid mimicking bacterial meningitis. Thorough investigation of the cerebrospinal fluid did not reveal evidence of bacteria or fungi. Clinical deterioration was observed in spite of empiric treatment with antibiotics...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000082002.66513.EA
更新日期:2003-09-01 00:00:00
abstract::This case study illustrates the relationship between hypothyroidism and bronchial asthma. As seen here, even slow and cautious restoration of the euthyroid state may lead to problems in the management of asthma. Thus routine or aggressive replacement therapy for thyroid hypofunction in the asthmatic population is not ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198403000-00037
更新日期:1984-03-01 00:00:00
abstract::This case study supports the plea by a number of psychiatrists for thorough psychiatric and psychologic screening of all persons seeking sexual reassignment surgery. The patient, a female impersonator taking estrogen, was seriously considering such an operation in order to cope with identity problems and an inability ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197504000-00017
更新日期:1975-04-01 00:00:00
abstract::An unusual volar and radial perilunate transscaphoid fracture dislocation is reported. Treatment of perilunate transscaphoid fracture dislocations by closed reduction often produces a poor result. Early open reduction may be followed by a good result, but if open reduction is impossible, proximal row carpectomy is adv...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197507000-00025
更新日期:1975-07-01 00:00:00
abstract:BACKGROUND:Oxybutynin is a tertiary amine and has chemical similarities like protamine sulfate. Protamine sulfate's effect on bacterial viability has been shown in some studies; however, there is scanty data regarding the effect of oxybutynin on bacterial viability. Accordingly, the aim of the present study was to inve...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000305885.23903.71
更新日期:2008-03-01 00:00:00
abstract:: Acute pulmonary embolism (PE) is a common clinical condition with presentations that may vary from asymptomatic subsegmental emboli to massive vascular obstruction and shock with high risk of death. Identifying patients at highest risk for death is critical to select those who would benefit most from thrombolytic the...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e318268dbca
更新日期:2012-10-01 00:00:00
abstract::Aminoglycosides have been reported to cause tetany by inducing renal wasting of magnesium and secondary hypocalcemia. A 9-year-old girl with AIDS was brought to the emergency department because of tetany. She had just finished a 3-week course of intravenous tobramycin for bronchiectasis and had an elevated serum tobra...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199611000-00019
更新日期:1996-11-01 00:00:00
abstract::We investigated psyllium fiber supplementation as a means of enhancing the cholesterol-lowering effect of the phase I American Heart Association diet. Fifty-nine subjects with total serum cholesterol (TC) levels ranging from 5.56 to 10.24 mmol/L (215 to 396 mg/dL) were given a 2-month dietary lead-in followed by 3 mon...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007611-199010000-00005
更新日期:1990-10-01 00:00:00
abstract::A retrospective study of 45 patients hospitalized with blastomycosis of bones or joints revealed 41 cases of osteomyelitis and 12 cases of septic arthritis. The majority were men (35 [78%] patients) and non-Aboriginal (32 [71%] patients). Median time from the onset of symptoms to hospitalization was shorter in women t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3180487a92
更新日期:2007-06-01 00:00:00
abstract::Axillary and palmar hyperhidrosis are featured prominently in the literature, but no previous studies have detailed a treatment regimen for specific excessive localized sweating of the face and scalp. In this report, a patient was treated for this condition with a combination of clonidine hydrochloride (0.3 mg to 0.4 ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::There are presently more than 7,000 Vietnamese refugees living in the greater New Orleans area. This paper summarizes the health and information on nutrition now available regarding Vietnamese refugees living in the United States. It is hoped that this effort will add to the documentation of the health changes occurri...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197910000-00024
更新日期:1979-10-01 00:00:00
abstract::This is a case which highlights unique diagnostic challenges in the evaluation of a previously healthy patient presenting with a myelopathy initially most concerning for malignancy. However, timely recognition and nonoperative therapy of unexpected spinal sarcoidosis with corticosteroidal therapy was crucial in averti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181e90745
更新日期:2010-09-01 00:00:00
abstract::A man who received therapeutic irradiation to limited areas of each lung for intrapulmonary Hodgkin's disease developed bronchioalveolar carcinoma in the same areas more than 20 years later. This is the first report of a malignant process developing in areas of the lung that had been previously irradiated for treatmen...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198305000-00046
更新日期:1983-05-01 00:00:00
abstract::Over the past 10 years, one of us (M.C.A.) has treated 92 patients who required operation for symptoms associated with alcohol-induced chronic fibrocalcific pancreatitis. Four of these patients had duodenal obstruction. All four had had lateral pancreaticojejunostomy to relieve pancreatic ductal obstruction and associ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:1991-03-01 00:00:00
abstract::Diabetic ketoacidosis can be effectively and economically treated by using low-dose intravenous insulin and 2 to 3 liters of isotonic saline at 500 ml/hr to replace extracellular fluids, followed by 2 to 4 L of 5% glucose in 0.45% saline with potassium chloride and/or potassium phosphate to replace intracellular fluid...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198707000-00017
更新日期:1987-07-01 00:00:00
abstract::Schwannoma arising within breast parenchyma is rare. We report such a case in a 50-year-old woman. The tumor, which measured 7 mm, is the smallest and the only mammographically detected schwannoma of the breast thus far reported. Clinicians should be aware that this benign tumor of breast may simulate a malignant neop...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199602000-00018
更新日期:1996-02-01 00:00:00
abstract::Chemotherapy with radiation has become more popular than radiotherapy alone for patients with locally advanced head and neck cancer because of the successful results associated with it. We report the case of a 67-year-old man with hypopharyngeal cancer invading the prevertebral fascia who became free of disease after ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000125170.34916.FB
更新日期:2004-11-01 00:00:00
abstract::Despite the remarkably low mortality from poisonous snakebites in the United States during the past few years, there has been little improvement in preventing deformities of digits. Using a retrospective study of 207 cases of poisonous snakebite, I present a method that has been highly successful in avoiding deformiti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198506000-00020
更新日期:1985-06-01 00:00:00
abstract::Thirty-three anterior staple capsulorrhaphies of the shoulder were reviewed at an average 49.7 months postoperatively (range 12 to 127 months); one postoperative dislocation occurred. The patients' quality of athletic participation improved with surgical therapy in 50%, remained the same in 38%, and was lowered in 12%...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199005000-00009
更新日期:1990-05-01 00:00:00
abstract::Payment systems in the US healthcare system have rewarded physicians for services and attempted to control healthcare spending, with rewards and penalties based upon projected goals for future spending. The incorporation of quality goals and alternatives to fee-for-service was introduced to replace the previous system...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000626
更新日期:2017-04-01 00:00:00
abstract::We have described a patient with vaccinia necrosum after smallpox vaccination for persistent herpes labialis. The patient eventually recovered after surgical resection of the lesion and multiple courses of vaccinia immune globulin and methisazone. This report emphasizes the needless risks of vaccinating patients with ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198103000-00044
更新日期:1981-03-01 00:00:00
abstract::Tobacco use is associated with numerous illnesses and contributes to as many as 400,000 deaths in the United States each year. Most tobacco use in the United States is in the form of cigarette smoking, but smokeless tobacco use is particularly high in certain areas and within certain subpopulations. Among US adults, s...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2000-05-01 00:00:00
abstract::In El Paso County, Texas, 73 domestic wells were sampled using a variety of selective media to determine the extent of bacterial contamination of the groundwater on the US side of the United States-Mexico border. Thirteen wells were contaminated by fecal coliforms, whereas other wells contained a variety of bacterial ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199412000-00004
更新日期:1994-12-01 00:00:00
abstract::A 63-year-old male patient with a history of bipolar I disorder presented to the emergency department in an acutely psychotic state. The patient had just returned from vacation in a malarial high-risk area and, as a result, had taken five weekly doses of mefloquine for prophylaxis. The patient's bipolar disorder was b...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e318167a9e2
更新日期:2008-05-01 00:00:00
abstract::This descriptive study prospectively examined the performance and supervision of interpretive and procedural skills during an internal medicine clerkship. Students (N = 150) documented having done 7 required and 12 elective skills. Preceptors of required skills were interns (44%), residents (29%), attending physicians...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199606000-00009
更新日期:1996-06-01 00:00:00