Direct activation of neutrophil chemiluminescence by rheumatoid sera and synovial fluid.

abstract：:The cartilage-pannus junction has been studied in multiple sections from 23 rheumatoid joints. Changes suggesting a metaplastic reaction of the articular cartilage, termed transitional fibroblastic zone, were commonly found in hips and knees, but were rarely present in metatarsophalangeal joints, in which an invasive ...

journal_title：Annals of the rheumatic diseases

authors： Allard SA,Muirden KD,Maini RN

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:To determine whether the number of patients required in a therapeutic trial that uses progression of radiological abnormalities as the outcome measure would be similar for multiple centres. METHODS:The progression of radiological damage to the fingers and wrists of patients with rheumatoid arthritis in five ...

journal_title：Annals of the rheumatic diseases

authors： Sharp JT,Wolfe F,Corbett M,Isomaki H,Mitchell DM,Furst DE,Sibley J,Shipley M

更新日期：1993-05-01 00:00:00

abstract：:Cellular immunity to cartilage proteoglycans may be responsible for sustaining chronic inflammation in ankylosing spondylitis. This hypothesis was examined by measuring peripheral blood and synovial fluid mononuclear cell proliferation in five preparations of human cartilage proteoglycan monomer in vitro. Peripheral b...

journal_title：Annals of the rheumatic diseases

authors： Jobanputra P,Choy EH,Kingsley GH,Sieper J,Palacios-Boix AA,Heinegård D,Panayi GS

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:To assess associations between joint-specific hand symptoms and self-reported and performance-based functional status. METHODS:Participants were from the population-based Johnston County Osteoarthritis Project. Symptoms in the distal interphalangeal (DIP), proximal interphalangeal (PIP), first carpometacarpa...

journal_title：Annals of the rheumatic diseases

authors： Elliott AL,Kraus VB,Fang F,Renner JB,Schwartz TA,Salazar A,Huguenin T,Hochberg MC,Helmick CG,Jordan JM

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:The effect of adalimumab on hand osteoporosis was examined and related to radiographic joint damage in the three treatment arms of the PREMIER study: adalimumab plus methotrexate, adalimumab and methotrexate monotherapy. Predictors of hand bone loss were also searched for. METHODS:768 patients (537 fulfilled...

journal_title：Annals of the rheumatic diseases

authors： Hoff M,Kvien TK,Kälvesten J,Elden A,Haugeberg G

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Despite the importance of timely management of patients with inflammatory arthritis (IA), delays exist in its diagnosis and treatment. OBJECTIVE:To perform a systematic literature review to identify strategies addressing these delays to inform an American College of Rheumatology (ACR)/European League Agains...

journal_title：Annals of the rheumatic diseases

authors： Villeneuve E,Nam JL,Bell MJ,Deighton CM,Felson DT,Hazes JM,McInnes IB,Silman AJ,Solomon DH,Thompson AE,White PH,Bykerk VP,Emery P

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To identify predictors of radiographic progression in a 2-year randomised, double-blind, clinical study (CIMESTRA) of patients with early rheumatoid arthritis (RA). METHODS:Patients with early RA (n = 130) were treated with methotrexate, intra-articular betamethasone and ciclosporin/placebo-ciclosporin. Base...

journal_title：Annals of the rheumatic diseases

authors： Hetland ML,Ejbjerg B,Hørslev-Petersen K,Jacobsen S,Vestergaard A,Jurik AG,Stengaard-Pedersen K,Junker P,Lottenburger T,Hansen I,Andersen LS,Tarp U,Skjødt H,Pedersen JK,Majgaard O,Svendsen AJ,Ellingsen T,Lindegaard H,C

更新日期：2009-03-01 00:00:00

abstract：:Animals were injected intra-articularly with antigen after prior immunization with that antigen in Freund's incomplete adjuvant in order to precipitate immune complexes in the surfaces of menisci, ligaments, and cartilage. On reimmunization with antigen in Freund's complete adjuvant 10 weeks later, generally an arthri...

journal_title：Annals of the rheumatic diseases

authors： Fox A,Glynn LE

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Cancellous bone from patients with osteoarthritis (OA) has been reported to be undermineralised and that from patients with osteoporosis (OP) is more liable to fracture. Changes in the mineral component might be implicated in these processes. OBJECTIVES:To investigate the thermal stability and the mineral s...

journal_title：Annals of the rheumatic diseases

authors： Mkukuma LD,Imrie CT,Skakle JM,Hukins DW,Aspden RM

更新日期：2005-02-01 00:00:00

abstract：:Plasma DNA has been measured by a new physiochemical approach based on fluorimetric analysis of phenol extracted nucleic acids electrophoresed on polyacrylamide gels. This method is specific for native double-stranded DNA of molecular weight greater than 5 x 10(6). The use of plasma rigorously freed of leucocytes is e...

journal_title：Annals of the rheumatic diseases

authors： Klemp P,Meyers OL,Harley EH

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVE:To investigate the prediction of the postpartum onset of rheumatoid arthritis (RA). METHODS:Two thousand five hundred and forty seven healthy pregnant subjects were examined prospectively and the relation between serum rheumatoid factors (RF) and postpartum onset of RA was observed. Rheumatoid factors were m...

journal_title：Annals of the rheumatic diseases

authors： Iijima T,Tada H,Hidaka Y,Yagoro A,Mitsuda N,Kanzaki T,Murata Y,Amino N

更新日期：1998-08-01 00:00:00

abstract：:227 patients with psoriasis and various forms of arthritis have been kept under review. Psoriasis and inflammatory arthropathy was present in 168 patients, of whom 94 have been followed up for more than 10 years. An arthritis indistinguishable from rheumatoid disease was present in 78%, distal joint arthritis in 16-6%...

journal_title：Annals of the rheumatic diseases

authors： Roberts ME,Wright V,Hill AG,Mehra AC

更新日期：1976-06-01 00:00:00

abstract：:Collagenase etching has been used to show the microstructure of bone from patients suffering from primary osteoporosis. Both polished and unpolished surfaces of trabecular bone from femoral heads were treated with collagenase solution before study in the scanning electron microscope. The polished surfaces show the min...

journal_title：Annals of the rheumatic diseases

authors： Mackie IG,Green M,Clarke H,Isaac DH

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:Evidence was sought for genetic anticipation (disease occurring at an earlier age in subsequent generations, with increasing severity) in nodal osteoarthritis (NOA). METHODS:Age at symptom onset and disease severity was compared within 30 parent/offspring pairs with NOA. Correlation between the offspring age...

journal_title：Annals of the rheumatic diseases

authors： Wright GD,Regan M,Deighton CM,Wallis G,Doherty M

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis is associated with an unexplained increased risk of cardiovascular disease (CVD). Antibodies against human 60 kDa heat shock protein (anti-HSP60) are associated with the presence and severity of CVD. OBJECTIVES:To investigate whether anti-HSP60 antibodies are associated with prevalent C...

journal_title：Annals of the rheumatic diseases

authors： van Halm VP,Slot MC,Nurmohamed MT,Tervaert JW,Dijkmans BA,Voskuyl AE

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To investigate the significance of complement activation in patients with primary antiphospholipid syndrome (APS). METHODS:Thirty-six patients with primary APS, 42 control patients with non-systemic lupus erythematosus (SLE) connective tissue diseases, and 36 healthy volunteers were analysed retrospectively....

journal_title：Annals of the rheumatic diseases

authors： Oku K,Atsumi T,Bohgaki M,Amengual O,Kataoka H,Horita T,Yasuda S,Koike T

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Primary Sjögren's syndrome (pSS) is characterised by a chronic inflammation of exocrine glands. Salivary gland infiltrates, however, do not correlate well with disease symptoms, and a primary role for the salivary gland parenchyma in disease development has been suggested. Specifically, dysfunction of exocri...

journal_title：Annals of the rheumatic diseases

authors： Appel S,Le Hellard S,Bruland O,Brun JG,Omdal R,Kristjansdottir G,Theander E,Nordmark G,Kvarnström M,Eriksson P,Rönnblom L,Wahren-Herlenius M,Jonsson R

更新日期：2011-07-01 00:00:00

abstract：:Patients who develop reactive arthritis after yersinia enteritis are characterised by high and persisting IgA-anti-yersinia antibodies. We have further analysed the humoral immune response to yersinia in this condition. Total concentrations of IgM, IgG, IgA, and secretory IgA in the serum and specific anti-yersinia an...

journal_title：Annals of the rheumatic diseases

authors： Granfors K,Toivanen A

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:The first genome-wide association study (GWAS) of systemic sclerosis (SSc) demonstrated three non-major histocompatibility complex (MHC) susceptibility loci. The goal of this study was to investigate the impact of these gene variants on survival and severity of interstitial lung disease (ILD) in SSc. METHODS...

journal_title：Annals of the rheumatic diseases

authors： Sharif R,Mayes MD,Tan FK,Gorlova OY,Hummers LK,Shah AA,Furst DE,Khanna D,Martin J,Bossini-Castillo L,Gonzalez EB,Ying J,Draeger HT,Agarwal SK,Reveille JD,Arnett FC,Wigley FM,Assassi S

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:Advanced imaging studies have demonstrated that urate deposition in periarticular structures, such as tendons, is common in gout. The aim of this study was to investigate the effects of monosodium urate monohydrate (MSU) crystals on tenocyte viability and function. METHODS:The histological appearance of ten...

journal_title：Annals of the rheumatic diseases

authors： Chhana A,Callon KE,Dray M,Pool B,Naot D,Gamble GD,Coleman B,McCarthy G,McQueen FM,Cornish J,Dalbeth N

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:To compare patterns of arteriographic lesions of the aorta and primary branches in patients with Takayasu's arteritis (TAK) and giant cell arteritis (GCA). METHODS:Patients were selected from two North American cohorts of TAK and GCA. The frequency of arteriographic lesions was calculated for 15 large arter...

journal_title：Annals of the rheumatic diseases

authors： Grayson PC,Maksimowicz-McKinnon K,Clark TM,Tomasson G,Cuthbertson D,Carette S,Khalidi NA,Langford CA,Monach PA,Seo P,Warrington KJ,Ytterberg SR,Hoffman GS,Merkel PA,Vasculitis Clinical Research Consortium.

更新日期：2012-08-01 00:00:00

abstract：:A study of 163 patients with ankylosing spondylitis seen on 433 occasions showed that active inflammatory disease was strongly associated with the presence of Klebsiella pneumoniae in the faeces (P less than 0.001). Sequential studies showed that in patients with inactive disease the presence of a positive culture for...

journal_title：Annals of the rheumatic diseases

authors： Ebringer RW,Cawdell DR,Cowling P,Ebringer A

更新日期：1978-04-01 00:00:00

abstract：OBJECTIVE:To identify potential risk factors for the onset of inflammatory arthritis (IA) in a large cohort of patients with psoriatic arthritis (PsA) of recent onset. METHODS:We recruited cases with psoriasis and an onset of IA within the past 5 years. Controls were patients who had psoriasis but no arthritis. We ass...

journal_title：Annals of the rheumatic diseases

authors： Pattison E,Harrison BJ,Griffiths CE,Silman AJ,Bruce IN

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:To characterise optimal screening strategies for latent tuberculosis infection (LTBI) prior to the initiation of anti-tumour necrosis factor therapy. METHODS:Patients in 62 German rheumatology centres were evaluated for LTBI. Each patient was screened with a tuberculin skin test (TST) and one form of an int...

journal_title：Annals of the rheumatic diseases

authors： Kleinert S,Tony HP,Krueger K,Detert J,Mielke F,Rockwitz K,Schwenke R,Burmester GR,Diel R,Feuchtenberger M,Kneitz C

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To study the correlation between ankle and knee cartilage morphology to test the hypothesis that knee joint cartilage loss in gonarthritis can be estimated retrospectively using quantitative MRI analysis of the knee and ankle and established regression equations; and to test the hypothesis that sex difference...

journal_title：Annals of the rheumatic diseases

authors： Eckstein F,Siedek V,Glaser C,Al-Ali D,Englmeier KH,Reiser M,Graichen H

更新日期：2004-11-01 00:00:00

abstract：:A novel explanation for the natural history of joint destruction in the early phase of ankylosing spondylitis is proposed on the basis of the clinical history, x-ray appearance, operative findings, and histopathology of a young patient believed to be suffering from the peripheral form of this disease. ...

journal_title：Annals of the rheumatic diseases

authors： Pasion EG,Goodfellow JW

更新日期：1975-02-01 00:00:00

abstract：:A 15 year old girl who had pain, oedema of her left hand, and fever of four months' duration is described. Marked demineralisation of her hand was shown by radiography, and increased articular uptake by technetium-99m bone scan. All these changes were indistinguishable from reflex sympathetic dystrophy. After two admi...

journal_title：Annals of the rheumatic diseases

authors： Rodriguez-Moreno J,Ruiz-Martin JM,Mateo-Soria L,Rozadilla A,Roig-Escofet D

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVES:To compare the prevalence of osteoarthritis (OA) of the hip, tibiofemoral and patellofemoral joints in a skeletal population. METHODS:A total of 785 adult English skeletons (695 Saxon or Mediaeval origin) were examined for OA using established criteria. RESULTS:Twenty nine skeletons had hip OA, compared wi...

journal_title：Annals of the rheumatic diseases

authors： Rogers J,Dieppe P

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:Systemic lupus erythematosus (SLE) is a serious multisystem autoimmune disease, mediated by disrupted B cell quiescence and typically treated with glucocorticoids. We studied whether B cells in SLE are regulated by the glucocorticoid-induced leucine zipper (GILZ) protein, an endogenous mediator of anti-infla...

journal_title：Annals of the rheumatic diseases

authors： Jones SA,Toh AE,Odobasic D,Oudin MA,Cheng Q,Lee JP,White SJ,Russ BE,Infantino S,Light A,Tarlinton DM,Harris J,Morand EF

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:The impact of immunosuppression on postoperative outcomes has primarily been studied in patients undergoing joint replacement surgery. We aimed to evaluate the impact of biologics and glucocorticoids on outcomes after other major surgeries. METHODS:This retrospective cohort study used Medicare data 2006-201...

journal_title：Annals of the rheumatic diseases

authors： George MD,Baker JF,Winthrop KL,Goldstein SD,Alemao E,Chen L,Wu Q,Xie F,Curtis JR

更新日期：2020-05-01 00:00:00