Expression of the Escherichia coli IrgA homolog adhesin is regulated by the ferric uptake regulation protein.

abstract：:To assess the role of mannosylated lipoarabinomannan (ManLAM) in the inflammatory and apoptotic response of mycobacteria-infected and uninfected, bystander cells we applied a mouse macrophage model of infection with avirulent strains--Mycobacterium bovis BCG, Mycobacterium tuberculosis (MTB) H37Ra and compared with a ...

journal_title：Microbial pathogenesis

authors： Wojtas B,Fijalkowska B,Wlodarczyk A,Schollenberger A,Niemialtowski M,Hamasur B,Pawlowski A,Krzyzowska M

更新日期：2011-07-01 00:00:00

abstract：:The therapeutic use of probiotics for supporting the antibiotic action against gastrointestinal disorders is a current trend and emerging applications have gained popularity because of their support for various microbiological activities in digestive processes. Microorganisms isolated from kefir with great probiotic p...

journal_title：Microbial pathogenesis

authors： Lima MDSF,Souza KMS,Albuquerque WWC,Teixeira JAC,Cavalcanti MTH,Porto ALF

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:Pneumococcal infections have caused morbidity and mortality globally. Streptococcus pneumoniae (pneumococci) are commensal bacteria that colonize the nasopharynx, asymptomatically. From there, pneumococci can spread in the lungs causing pneumonia and disseminate in the bloodstream causing bacteremia (sepsi...

journal_title：Microbial pathogenesis

authors： Rahman NA,Sharudin A,Diah S,Muharram SH

更新日期：2017-09-01 00:00:00

abstract：:Enterococci are opportunistic pathogens known to cause numerous clinical infections and complications in humans. Adhesin-mediated binding to extracellular matrix (ECM) proteins of the host is thought to be a crucial step in the pathogenesis of these bacterial infections. Adhesin of collagen from Enterococcus faecalis ...

journal_title：Microbial pathogenesis

authors： Hall AE,Gorovits EL,Syribeys PJ,Domanski PJ,Ames BR,Chang CY,Vernachio JH,Patti JM,Hutchins JT

更新日期：2007-08-01 00:00:00

abstract：:According to the WHO factsheet, although approximately half a million brucellosis cases are reported annually, the true incidence is always 10-25 times higher than the reported number of cases. Therefore, we face a common yet uncommonly recognized entity of brucellosis, which highlights the importance of providing pre...

journal_title：Microbial pathogenesis

authors： Avijgan M,Rostamnezhad M,Jahanbani-Ardakani H

更新日期：2019-04-01 00:00:00

abstract：:Multidrug-resistant (MDR) bacteria are a growing threat to humans across the world. Antibiotic resistance is a global problem that has developed through continuous antibiotic use, combinatorial antibiotic use, pesticide-antibiotic cross-resistance, and horizontal gene transfer, as well as various other modes. Pesticid...

journal_title：Microbial pathogenesis

authors： Rangasamy K,Athiappan M,Devarajan N,Samykannu G,Parray JA,Aruljothi KN,Shameem N,Alqarawi AA,Hashem A,Abd Allah EF

更新日期：2018-01-01 00:00:00

abstract：:Up to 28-fold differences in vacA expression in Helicobacter pylori strains grown in vitro were demonstrated by real time quantitative RT-PCR. These large differences in expression were unrelated to putative -35 and -10 motifs or to other untranslated sequences upstream of the ATG start site. The lack of correlation b...

journal_title：Microbial pathogenesis

authors： Ayala G,Chihu L,Perales G,Fierros-Zárate G,Hansen LM,Solnick JV,Sánchez J

更新日期：2004-09-01 00:00:00

abstract：:Siderophores are low molecular weight molecules that allow bacteria to acquire iron from host cell proteins. 2,3-dihydroxybenzoic acid (DHBA) is the only known siderophore produced by the intracellular pathogen Brucella abortus. Here its role in virulence was assessed by evaluating the ability of a mutant with a disru...

journal_title：Microbial pathogenesis

authors： Parent MA,Bellaire BH,Murphy EA,Roop RM 2nd,Elzer PH,Baldwin CL

更新日期：2002-05-01 00:00:00

abstract：:Diagnosis of toxoplasmosis is an important issue, especially in at-risk patients. The molecular methods showed a promising future for such diagnosis; however, the method itself and the target sequence to be detected is an important part of accurate detection of the infection. The aim of the present study was to evalua...

journal_title：Microbial pathogenesis

authors： Valian HK,Mirhendi H,Mohebali M,Shojaee S,Fallahi S,Jafari R,Kheirandish F,Mousavi P

更新日期：2020-03-01 00:00:00

abstract：:Chlamydia persistence is a viable but non-replicative stage, induced by several sub-lethal stressor agents, including beta-lactam antibiotics. So far, no data about the connection between doxycycline and chlamydial persistence has been described in literature. We investigated the ability of doxycycline to induce C. tr...

journal_title：Microbial pathogenesis

authors： Marangoni A,Zalambani C,Marziali G,Salvo M,Fato R,Foschi C,Re MC

更新日期：2020-10-01 00:00:00

abstract：:The clinical course of infection with Mycobacterium leprae varies widely and depends on the pattern of the host immune response. Dendritic cells play an important role in the activation of the innate and adaptive immune system and seem to be essential for the development of the disease. To analyze the presence of epid...

journal_title：Microbial pathogenesis

authors： Hirai KE,Aarão TL,Silva LM,de Sousa JR,de Souza J,Dias LB Jr,Carneiro FR,Fuzii HT,Quaresma JA

更新日期：2016-02-01 00:00:00

abstract：:Periodontitis is a highly prevalent infective and inflammatory disease with an adverse impact on systemic health. Isorhamnetin, a flavonoid mainly isolated from Hippophae fhamnoides L. fruit, has been reported to have anti-inflammatory effect. This study aimed to investigate the anti-inflammatory effects and mechanism...

journal_title：Microbial pathogenesis

authors： Qi F,Sun JH,Yan JQ,Li CM,Lv XC

更新日期：2018-07-01 00:00:00

abstract：:Multidrug-resistant (MDR) pathogens are currently causing serious problems globally in the medical setting. Improper and extensive usage of antibiotics results in a selective pressure supporting the rise of antibiotic-resistant microbes. Many key cellular bacterial components, including enzymes and small noncoding RNA...

journal_title：Microbial pathogenesis

authors： Shin J,Prabhakaran VS,Kim KS

更新日期：2018-03-01 00:00:00

abstract：:Mycobacterium avium complex (MAC) strains from AIDS and non-AIDS patients and from the environment were studied for their colony morphology and virulence in beige mice. The majority of the MAC isolates from AIDS patients, in contrast to those from non-AIDS patients and the environment, showed increased virulence. Simi...

journal_title：Microbial pathogenesis

authors： Reddy VM,Parikh K,Luna-Herrera J,Falkinham JO 3rd,Brown S,Gangadharam PR

更新日期：1994-02-01 00:00:00

abstract：:The closely related Shiga toxins, Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2), can bind to Gb3 receptors. However, Stx2-producing enterohemorrhagic Escherichia coli (EHEC) strains are more commonly associated with serious human disease (viz., hemolytic-uremic syndrome) than Stx1-producing strains. To clarify the rel...

journal_title：Microbial pathogenesis

authors： Shimizu T,Sato T,Kawakami S,Ohta T,Noda M,Hamabata T

更新日期：2007-08-01 00:00:00

abstract：:With the growing interest in probiotic microorganisms based on their well established immense health benefits, the present investigation was aimed to assess the adhesion potential and safety of probiotic Lactobacillus rhamnosus MTCC- 5897 (LR) before it can be put into a probiotic formulations. L. rhamnosus showed an ...

journal_title：Microbial pathogenesis

authors： Bhat MI,Singh VK,Sharma D,Kapila S,Kapila R

更新日期：2019-05-01 00:00:00

abstract：:Type VI secretion systems (T6SSs) have been identified recently in several Gram-negative organisms and have been shown to be associated with virulence in some bacterial pathogens. A T6SS of Yersinia pestis CO92 (locus YPO0499-YPO0516) was deleted followed by investigation of the phenotype of this mutation. We observed...

journal_title：Microbial pathogenesis

authors： Robinson JB,Telepnev MV,Zudina IV,Bouyer D,Montenieri JA,Bearden SW,Gage KL,Agar SL,Foltz SM,Chauhan S,Chopra AK,Motin VL

更新日期：2009-11-01 00:00:00

abstract：:The corticosteroid-treated animal is well established as an experimental model for the study of Pneumocystis carinii pneumonitis (PCP). Latent or acquired infection with P. carinii in the murine lung progresses to fatal pneumonitis when the host is profoundly immunocompromized. In this study the effects of five immuno...

journal_title：Microbial pathogenesis

authors： Oz HS,Hughes WT,Rehg JE,Thomas EK

更新日期：2000-09-01 00:00:00

abstract：:Bovine tuberculosis (bTB) is usually diagnosed in vivo and ex vivo on the basis of delayed hypersensitivity reactions with a complex pool of antigens named bovine tuberculin (PPDB). The IFN-γ release assay (IGRA) for bTB is a blood-based assay that improves detection of infected cattle at early stages that escape skin...

journal_title：Microbial pathogenesis

authors： Alvarez AH,Gutiérrez-Ortega A,Gómez-Entzin V,Pérez-Mayorga G,Naranjo-Bastién J,González-Martínez V,Milián-Suazo F,Martínez-Velázquez M,Herrera-Rodríguez S,Hinojoza-Loza E

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:Tuberculosis (TB) is considered as a serious complication for organ transplant recipients; therefore, the detection and appropriate treatment of latent infection are recommended for preventing active TB infections in the future. The objective of this review is to conduct a systematic review and meta-analys...

journal_title：Microbial pathogenesis

authors： Rahimifard N,Mahmoudi S,Mamishi S,Pourakbari B

更新日期：2018-12-01 00:00:00

abstract：:Binding of human enterotoxigenic Escherichia coli (ETEC) to the small intestine is a prerequisite for colonization and is mediated by colonization factor (CF) antigens. Coli surface antigen 6 (CS6) is considered a CF but binding to isolated enterocytes has not been established. In this study bacteria expressing CS6 we...

journal_title：Microbial pathogenesis

authors： Helander A,Hansson GC,Svennerholm AM

更新日期：1997-12-01 00:00:00

abstract：:Pertussis toxin (PT) is an important virulence determinant of Bordetella pertussis and one of the major protective antigens against whooping cough. The genes coding for PT have recently been cloned, but attempts to express them in Escherichia coli have been unsuccessful. We therefore explored the possibility of expres...

journal_title：Microbial pathogenesis

authors： Runeberg-Nyman K,Engström O,Löfdahl S,Ylöstalo S,Sarvas M

更新日期：1987-12-01 00:00:00

abstract：:Considered to be a potential "superbug", methicillin-resistant Staphylococcus aureus (MRSA) has been one of the major recent infectious pathogens and thus poses a challenge to hospital infection control. The mobile genetic element staphylococcal chromosomal cassette mec (SCCmec) carries both the mecA or mecC gene, enc...

journal_title：Microbial pathogenesis

authors： Liu J,Chen D,Peters BM,Li L,Li B,Xu Z,Shirliff ME

更新日期：2016-12-01 00:00:00

abstract：:Catheter associated urinary tract infection (CAUTI) is a highly prevalent hospital-acquired infection that is predominantly caused by uropathogenic Escherichia coli (UPEC). It adheres on catheter surface using type I pili as the initial step of pathogenesis that progresses to form biofilm. In this study, potential inh...

journal_title：Microbial pathogenesis

authors： Miryala S,Makala H,Yadavali SP,Venkatasubramanian U,Subbaiah N,Srinandan CS

更新日期：2020-01-01 00:00:00

abstract：:Infectious urinary stones account for about 10% of all urinary stones. In 50% of cases urolithiasis is a recurrent illness, which can lead to the loss of a kidney if not properly treated. One of the reasons for recurrence of the disease may be the ability of bacteria to invade urothelial cells, persist in the host cel...

journal_title：Microbial pathogenesis

authors： Torzewska A,Budzyńska A,Białczak-Kokot M,Różalski A

更新日期：2014-06-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) is acknowledged a fulminating infectious pathogen affecting the pig farming industry, and current vaccines and drugs could hardly inhibit this virus. The 2', 5'-oligoadenylate synthetase (OASs) have antiviral activities, but the role(s) played by porcine OAS2...

journal_title：Microbial pathogenesis

authors： Zhao M,Wan B,Li H,He J,Chen X,Wang L,Wang Y,Xie S,Qiao S,Zhang G

更新日期：2017-10-01 00:00:00

abstract：:Along with robust immunogenicity, an ideal vaccine candidate should be able to produce a long lasting protection. In this regard, the frequency of memory B-cells is possibly an important factor in memory B-cell persistency and duration of immunological memory. On this basis, binding domains of tetanus toxin (HcT), bot...

journal_title：Microbial pathogenesis

authors： Rezaie E,Nekoie H,Miri A,Oulad G,Ahmadi A,Saadati M,Bozorgmehr M,Ebrahimi M,Salimian J

更新日期：2019-02-01 00:00:00

abstract：:Salmonella typhimurium SL3261 (aroA mutant) expressing a recombinant Mycoplasma hyopneumoniae antigen was used to orally immunize swine against porcine enzootic pneumonia. This construct, designated S. typhimurium aro A SL3261 (pKF1), expressed a recombinant protein containing the carboxy-terminal 11 kDa of a 42 kDa M...

journal_title：Microbial pathogenesis

authors： Fagan PK,Walker MJ,Chin J,Eamens GJ,Djordjevic SP

更新日期：2001-02-01 00:00:00

abstract：:As an economic devastating virus, porcine reproductive and respiratory syndrome virus (PRRSV) has spread globally, and seriously hinders the healthy development of the swine industry worldwide. In recent years, however, recombinant PRRSV strains are continuously emerging, resulting in the death of a large number of pi...

journal_title：Microbial pathogenesis

authors： Song Z,Zhang Q,Chen Y,Shen H,Yang G,Jiang P,Chen JL,Lin L

更新日期：2020-12-01 00:00:00

abstract：:Thanks to the progress and decreasing costs in genome sequencing technologies, more than 250,000 bacterial genomes are currently available in public databases, covering most, if not all, of the major human-associated phylogenetic groups of these microorganisms, pathogenic or not. In addition, for many of them, sequenc...

journal_title：Microbial pathogenesis

authors： Anani H,Zgheib R,Hasni I,Raoult D,Fournier PE

更新日期：2020-12-01 00:00:00