Abstract:
:Sperm have generally been supposed to penetrate the zona pellucida surrounding the mammalian egg with the aid of a protease, acrosin. Difficulties associated with this view are discussed and an alternative, mechanical hypothesis introduced. The calculated force exerted by individual sperm is too small to permit the rupture of any but the weakest of secondary chemical bonds. Mechanical progress through the zona must rely on stress relaxation in a viscoelastic medium. The known properties of the zona appear to be consistent with such a mechanism of penetration.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Green DP,Purves RDdoi
10.1016/S0006-3495(84)84207-1subject
Has Abstractpub_date
1984-04-01 00:00:00pages
659-62issue
4eissn
0006-3495issn
1542-0086pii
S0006-3495(84)84207-1journal_volume
45pub_type
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