Stromal invasion in endometrial adenocarcinoma.

Abstract:

:The ability to predict myometrial invasion by endometrial adenocarcinoma is useful for preoperative treatment purposes. The presence of stromal invasion is one possible method of predicting myometrial invasion, but criteria for the presence of stromal invasion have been lacking. Recently, criteria for its detection were proposed. We evaluated the validity of the proposed criteria in two conditions: (1) atypical hyperplasia (119 cases) and (2) endometrial adenocarcinoma Stage I, grade 1 (83 cases). Adenocarcinoma without stromal invasion according to the criteria of Kurman and Norris was present in 43 cases and adenocarcinoma with stromal invasion was present in 40 cases. This series demonstrated the ability of prehysterectomy endometrial sampling to predict the probability of myometrial penetration. In addition, none of our patients without stromal invasion in the resected uterus had myometrial penetration and no metastases have occurred. In those showing stromal invasion in the excised uterus, the myometrium was invaded in 34 of 51 cases (67%). Since myometrial penetration was not present when there was no stromal invasion in the resected uterus, stromal invasion deserves further evaluation and should be considered in future classification of endometrial adenocarcinoma.

journal_name

Am J Obstet Gynecol

authors

King A,Seraj IM,Wagner RJ

doi

10.1016/0002-9378(84)90283-7

subject

Has Abstract

pub_date

1984-05-01 00:00:00

pages

10-4

issue

1

eissn

0002-9378

issn

1097-6868

pii

0002-9378(84)90283-7

journal_volume

149

pub_type

杂志文章
  • Ultrasonographic prediction of neonatal survival in extremely low-birth-weight infants.

    abstract:OBJECTIVE:Our purpose was to improve the accuracy of prenatal prognostication by directly correlating obstetric ultrasonographic measurements with neonatal survival. STUDY DESIGN:We studied 130 singleton live-born infants with birth weights between 500 and 1000 gm and who underwent complete ultrasonographic examinatio...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90606-j

    authors: Smith RS,Bottoms SF

    更新日期:1993-09-01 00:00:00

  • The effects of dexamethasone on plasma free androgens during the normal menstrual cycle.

    abstract::In order to evaluate the ovarian and adrenal contribution to peripheral plasma concentrations of total testosterone (TTe), indixes of the plasma concentrations of free testosterone (FTeI), free 17 beta-hydroxysteroid androgens (FHSI), and testosterone-binding globulin (TeBG) during the menstrual cycle, women were exam...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(76)90688-8

    authors: Kim MH,Rosenfield RL,Dupon C

    更新日期:1976-12-15 00:00:00

  • Tocolytic and hemodynamic effects of nifedipine in the ewe.

    abstract::The ability of the calcium antagonist nifedipine to inhibit uterine contractions during labor and in the postpartum period was measured in the ewe. The hemodynamic effects of tocolytic doses of this drug were measured and compared with the hemodynamic effects of equivalent doses of ritodrine. Intravenous nifedipine wa...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(85)90397-7

    authors: Golichowski AM,Hathaway DR,Fineberg N,Peleg D

    更新日期:1985-04-15 00:00:00

  • Pituitary response to bolus and continuous intravenous infusion of luteinizing hormone-releasing factor in normal women and women with polycystic ovarian syndrome.

    abstract::Plasma luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels were measured in response to luteinizing hormone-releasing factor (LRF), given as a 100 microgram intravenous bolus and/or as a 4 hour infusion of 0.2 microgram per minute to 27 normal menstruating women and 15 women with the polycystic ovar...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(78)90318-6

    authors: Mortimer RH,Lev-Gur M,Freeman R,Fleischer N

    更新日期:1978-03-15 00:00:00

  • Ectopic pregnancy following treatment with human gonadotropins.

    abstract::After treatment with human gonadotropins, 289 anovulatory women with apparently normal fallopian tubes became pregnant 379 times. Ten ectopic pregnancies in nine women were diagnosed, for an incidence of 2.7% of all conceptions. All the ectopic pregnancies were found in the fallopian tubes. Four patients had also an i...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90006-0

    authors: Gemzell C,Guillome J,Wang CF

    更新日期:1982-08-01 00:00:00

  • Management of isoimmune neonatal thrombocytopenia.

    abstract::Two infants, who presented at birth with isoimmune thrombocytopenic purpura, are the basis for this report. The problems confronting the physician in treating an affected infant, as well as in the management of subsequent pregnancies after an infant with isoimmunization has been delivered, are discussed. In view of th...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(76)90008-9

    authors: Sitarz AL,Driscoll JM Jr,Wolff JA

    更新日期:1976-01-01 00:00:00

  • Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model.

    abstract:OBJECTIVE:Phosphatase and tensin homolog (PTEN) mutations are associated with human endometrial cancers, and PTEN heterozygote(+/-) mice have a high rate of endometrial neoplasia. The objective of this study was to evaluate an oral mTOR inhibitor (mTOR-I) on the reduction of endometrial hyperplasia in an animal model. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2006.10.872

    authors: Milam MR,Celestino J,Wu W,Broaddus RR,Schmeler KM,Slomovitz BM,Soliman PT,Gershenson DM,Wang H,Ellenson LH,Lu KH

    更新日期:2007-03-01 00:00:00

  • Maternal and paternal race/ethnicity are both associated with gestational diabetes.

    abstract:OBJECTIVE:The objective of the study was to examine the rates of gestational diabetes mellitus (GDM) associated with both maternal and paternal race/ethnicity. STUDY DESIGN:This was a retrospective cohort study of all women delivered within a managed care network. Rates of GDM were calculated for maternal, paternal, a...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2010.01.082

    authors: Caughey AB,Cheng YW,Stotland NE,Washington AE,Escobar GJ

    更新日期:2010-06-01 00:00:00

  • Identification of severe maternal morbidity during delivery hospitalizations, United States, 1991-2003.

    abstract:OBJECTIVE:This investigation aimed to identify pregnancy complications and risk factors for women who experienced severe maternal morbidity during the delivery hospitalization and to estimate severe maternal morbidity rates. STUDY DESIGN:We used the National Hospital Discharge Survey for 1991-2003 to identify delivery...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2007.12.020

    authors: Callaghan WM,Mackay AP,Berg CJ

    更新日期:2008-08-01 00:00:00

  • The cavitational ultrasonic surgical aspirator for cytoreduction in advanced ovarian cancer.

    abstract:OBJECTIVE:The cavitational ultrasonic surgical aspirator is a newer surgical instrument that has been shown to be effective in tumor resection. The purpose of this study was to evaluate its usefulness for cytoreduction of advanced ovarian cancer. STUDY DESIGN:Over a 24-month period patients with advanced ovarian cance...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(92)91345-b

    authors: Rose PG

    更新日期:1992-03-01 00:00:00

  • Trends in urodynamics study utilization in a Southern California managed care population.

    abstract:OBJECTIVE:We examined trends in overall and preoperative urodynamics utilization among women with stress urinary incontinence (SUI) to determine if practice patterns changed following publication of a 2012 randomized trial questioning the value of preoperative urodynamics in patients with uncomplicated SUI. STUDY DESI...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2015.06.062

    authors: Lippmann QK,Diwadkar GB,Zhou H,Menefee SA

    更新日期:2015-11-01 00:00:00

  • A hospital review of advanced gynecologic endoscopic procedures.

    abstract:OBJECTIVE:Our purpose was to review the findings of a Gynecologic Endoscopic Review Committee established to monitor and review operative endoscopic procedures performed by the staff at a large private hospital, Swedish Hospital Medical Center, in Seattle. STUDY DESIGN:Hospital charts of patients undergoing the endosc...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Smith DC,Donohue LR,Waszak SJ

    更新日期:1994-06-01 00:00:00

  • The effects of danazol on gonadotropins and steroid blood levels in normal and anovulatory women.

    abstract::The effect of Danazol, a new gonadotropin inhibitor, was examined in four categories of patients. (1) Ten normal women medicated orally with Danazol, 800 mg. daily for 91 days, showed no depression of serum LH, estrone, estradiol, or progesterone below control, second-day levels. The serum FSH was slightly depressed; ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Andrews MC,Wentz AC

    更新日期:1975-03-15 00:00:00

  • Natural history of chronic proteinuria complicating pregnancy.

    abstract:OBJECTIVE:Although the significance of proteinuria is well-documented for pregnancy complicated by preeclampsia or diabetes, protein excretion of up to 300 mg per day is considered normal for uncomplicated pregnancy. Our purpose was to determine the significance of otherwise "asymptomatic" proteinuria identified during...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)91692-5

    authors: Stettler RW,Cunningham FG

    更新日期:1992-11-01 00:00:00

  • Postpartum ultrasonographic findings associated with placenta accreta.

    abstract::Postpartum ultrasonographic examination of a patient with a retained placenta showed findings consistent with placenta accreta. The diagnosis was confirmed after surgery with histopathologic examination of the uterus. This case illustrates the possible clinical application of ultrasonography in the postpartum diagnosi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)91557-9

    authors: Shapiro JL,Sherer DM,Hurley JT,Metlay LA,Amstey MS

    更新日期:1992-09-01 00:00:00

  • Maternal-perinatal morbidity and mortality associated with adolescent pregnancy in Latin America: Cross-sectional study.

    abstract:OBJECTIVE:This study was undertaken to determine whether adolescent pregnancy is associated with increased risks of adverse pregnancy outcomes. STUDY DESIGN:We studied 854,377 Latin American women who were younger than 25 years during 1985 through 2003 using information recorded in the Perinatal Information System dat...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.10.593

    authors: Conde-Agudelo A,Belizán JM,Lammers C

    更新日期:2005-02-01 00:00:00

  • Acceptance of amniocentesis by low-income patients in an urban hospital.

    abstract::A study was made of increased accessibility of genetic services to low-income obstetric patients in Atlanta, Georgia. The proportion of black patients averaged 83%. Of 522 patients counseled from August, 1976, through 1978, 157 were offered amniocentesis, and 95 (61%) elected the procedure. For most of the patients (1...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(80)90004-6

    authors: Marion JP,Kassam G,Fernhoff PM,Brantley KE,Carroll L,Zacharias J,Klein L,Priest JH,Elsas LJ 2nd

    更新日期:1980-09-01 00:00:00

  • Competing risks model in screening for preeclampsia by maternal characteristics and medical history.

    abstract:OBJECTIVE:The purpose of this study was to develop a model for preeclampsia based on maternal demographic characteristics and medical history. STUDY DESIGN:This was a screening study of 120,492 singleton pregnancies at 11-13 weeks' gestation, including 2704 pregnancies (2.2%) that experienced preeclampsia. A survival-...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2015.02.018

    authors: Wright D,Syngelaki A,Akolekar R,Poon LC,Nicolaides KH

    更新日期:2015-07-01 00:00:00

  • Differential symptom response to parenteral estrogen and/or androgen administration in the surgical menopause.

    abstract::The investigation of estrogen and/or androgen administration on physical and psychological symptoms in the surgical menopause was carried out in a prospective, double-blind, crossover design. When patients who received either a combined estrogen-androgen drug or androgen alone were compared with those who received est...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-9378(85)90001-8

    authors: Sherwin BB,Gelfand MM

    更新日期:1985-01-15 00:00:00

  • Use of the combined tetanus-diphtheria and pertussis vaccine during pregnancy.

    abstract:OBJECTIVE:A recent increase in pertussis cases prompted the Advisory Committee on Immunization Practices to recommend administering the perinatal tetanus, diphtheria, and pertussis (Tdap) vaccine during each pregnancy. We sought to describe uptake of Tdap and identify predictors of vaccination in pregnancy. STUDY DESI...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2014.05.029

    authors: Goldfarb IT,Little S,Brown J,Riley LE

    更新日期:2014-09-01 00:00:00

  • Progesterone receptor polymorphisms and clinical response to 17-alpha-hydroxyprogesterone caproate.

    abstract:OBJECTIVE:Seventeen-alpha-hydroxyprogesterone caproate (17-OHPC) reduces recurrent preterm birth (PTB). We hypothesized that single nucleotide polymorphisms in the human progesterone receptor (PGR) affect response to 17-OHPC in the prevention of recurrent PTB. STUDY DESIGN:We conducted secondary analysis of a study of...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ajog.2011.03.048

    authors: Manuck TA,Lai Y,Meis PJ,Dombrowski MP,Sibai B,Spong CY,Rouse DJ,Durnwald CP,Caritis SN,Wapner RJ,Mercer BM,Ramin SM

    更新日期:2011-08-01 00:00:00

  • Innervation of the female levator ani muscles.

    abstract:OBJECTIVE:The objective of this study was to characterize the innervation of the human female levator ani muscles. STUDY DESIGN:Detailed dissections of the peripheral innervation of the iliococcygeal, pubococcygeal, puborectal, and coccygeal muscles were performed in 12 fresh-frozen female cadavers (aged, 32-100 years...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2002.124844

    authors: Barber MD,Bremer RE,Thor KB,Dolber PC,Kuehl TJ,Coates KW

    更新日期:2002-07-01 00:00:00

  • New approaches for the treatment of bacterial vaginosis.

    abstract:OBJECTIVE:Review alternative approaches to oral metronidazole for the treatment of bacterial vaginosis. STUDY DESIGN:Assessment of clinical trials on the treatment of bacterial vaginosis with regimens other than 5 to 7 days of metronidazole. RESULTS:Single-dose metronidazole, 2 gm orally, is as effective as 5- to 7-d...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/0002-9378(93)90346-k

    authors: Sweet RL

    更新日期:1993-08-01 00:00:00

  • Vasodilatory response of fetoplacental vasculature to adrenomedullin after constriction with the thromboxane sympathomimetic U46619.

    abstract:OBJECTIVE:This study was undertaken to determine whether adrenomedullin, a hypotensive peptide, decreases vasomotor tone in fetoplacental vasculature that has been constricted with the thromboxane sympathomimetic U46619. STUDY DESIGN:The fetoplacental vascular beds of 20 perfused human placental cotyledons were vasoco...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2000.108071

    authors: Hoeldtke NJ,Wagner RK,Calhoun BC,Hume RF Jr

    更新日期:2000-12-01 00:00:00

  • Rapid measurement of urinary pregnanediol glucuronide to diagnose ectopic pregnancy.

    abstract::We investigated the ability of a single, random, urinary pregnanediol-3 alpha-glucuronide level to differentiate early intrauterine from ectopic pregnancy. Thirty-four patients with intrauterine gestations were compared with 60 patients with ectopic pregnancies. Urinary pregnanediol-3 alpha-glucuronide was measured by...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90589-3

    authors: Sauer MV,Vermesh M,Anderson RE,Vijod AG,Stanczyk FZ,Lobo RA

    更新日期:1988-12-01 00:00:00

  • Pregnancy induces persistent changes in vascular compliance in primiparous women.

    abstract:OBJECTIVE:Pregnancy induces rapid, progressive, and substantial changes to the cardiovascular system. The low recurrence risk of preeclampsia, despite familial predisposition, suggests an adaptation associated with pregnancy that attenuates the risk for subsequent preeclampsia. We aimed to evaluate the persistent effec...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2015.01.005

    authors: Morris EA,Hale SA,Badger GJ,Magness RR,Bernstein IM

    更新日期:2015-05-01 00:00:00

  • Effects of plasma on the platelet antiaggregatory action of prostacyclin in pregnancy.

    abstract::Platelet-poor plasma from 13 nonpregnant, 33 normally pregnant, and eight preeclamptic women was incubated with prostacyclin. The ability of platelet-poor plasma to diminish the antiaggregatory effect of prostacyclin was assessed by measuring this effect on arachidonic acid-induced platelet aggregation. Platelet aggre...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(87)90370-x

    authors: Baker VV,Kort B,Cefalo RC

    更新日期:1987-04-01 00:00:00

  • Embryo fragmentation as a determinant of blastocyst development in vitro and pregnancy outcomes following embryo transfer.

    abstract:OBJECTIVE(S):To determine how the type of embryo fragmentation on day 3 affects progression of human embryos to blastocyst and pregnancy rates following embryo transfer. STUDY DESIGN:Retrospective analysis of all in vitro fertilization cycles in patients < or =40 years of age or younger from January 2002 through Decem...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2005.02.048

    authors: Stone BA,Greene J,Vargyas JM,Ringler GE,Marrs RP

    更新日期:2005-06-01 00:00:00

  • Trocar implantation metastasis after laparoscopy in patients with advanced ovarian cancer: can the risk be reduced?

    abstract:OBJECTIVE:The purpose of this study was to determine risk factors for trocar implantation metastasis after diagnostic laparoscopy in patients with primary or recurrent advanced ovarian cancer. STUDY DESIGN:Eighty-three women with primary advanced ovarian cancer and 21 women with recurrent ovarian cancer undergoing a l...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(99)70489-8

    authors: van Dam PA,DeCloedt J,Tjalma WA,Buytaert P,Becquart D,Vergote IB

    更新日期:1999-09-01 00:00:00

  • Ultrasonographic detection of abnormal fetal growth with the gestational age-independent, transverse cerebellar diameter/abdominal circumference ratio.

    abstract:OBJECTIVES:We prospectively evaluated the accuracy of a gestational age-independent method of detecting abnormal growth, the transverse cerebellar diameter/abdominal circumference ratio, and compared this with standard ultrasonographic methods of growth assessment. STUDY DESIGN:We prospectively studied 825 low-risk ob...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-9378(94)90035-3

    authors: Meyer WJ,Gauthier D,Ramakrishnan V,Sipos J

    更新日期:1994-10-01 00:00:00