Taurine release associated to volume regulation in rabbit lymphocytes.

abstract：:The inhibitor of growth (ING) family of proteins is an evolutionarily conserved family, with members present from yeast to humans. The mammalian ING proteins are candidate tumor suppressor proteins and accordingly can cooperate with p53 to arrest proliferation and induce apoptosis. ING proteins are also reported to fu...

journal_title：Journal of cellular biochemistry

authors： Shi X,Gozani O

更新日期：2005-12-15 00:00:00

abstract：:Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. We investigated the effect of a prior 30 days voluntary exercise protocol on STZ-diabetic CF1 mice. Glycemia, and the liver and skeletal muscle glycogen, mitochondrial function, and redox status were analyzed up to 5 days after STZ injection. An...

journal_title：Journal of cellular biochemistry

authors： de Carvalho AK,da Silva S,Serafini E,de Souza DR,Farias HR,de Bem Silveira G,Silveira PC,de Souza CT,Portela LV,Muller AP

更新日期：2017-04-01 00:00:00

abstract：:TNF is a key inflammatory cytokine with antiviral properties. Human adenoviruses encode several intracellular proteins that mediate the effects of TNF. Expression of the adenovirus immediate early E1A proteins induces viral genes and a host of cellular genes, drives G0 cells into S-phase, and induces apoptosis and sus...

journal_title：Journal of cellular biochemistry

authors： Wold WS

更新日期：1993-12-01 00:00:00

abstract：:Gastric cancer (GC) is the second most common cause of cancer death worldwide but could be more curable if diagnosed at an earlier stage. At present, the capability to predict the efficaciousness of molecular diagnosis for GC for each patient remains elusive. The purpose of this study was to identify tumor biomarkers ...

journal_title：Journal of cellular biochemistry

authors： Ai K,Jia Y,Li J,Wang C,Wang Y

更新日期：2018-11-13 00:00:00

abstract：:The activity of α-type cytosolic phospholipase A2 (cPLA2 α, group IVA PLA2 ), which releases arachidonic acid (AA), is mainly regulated by the Ca2+ -induced intracellular translocation/attachment of the enzyme to substrate membranes and its phosphorylation. We previously reported that tumor necrosis factor-α (TNFα) st...

journal_title：Journal of cellular biochemistry

authors： Nakamura H,Moriyama Y,Watanabe K,Tomizawa S,Yamazaki R,Takahashi H,Murayama T

更新日期：2017-12-01 00:00:00

abstract：:Wip1 belongs to the protein phosphatase C (PP2C) family, of which expression is up-regulated by a number of external stresses, and serves as a stress modulator in normal physiological conditions. When overexpressed, premature dephosphorylation of stress-mediators by Wip1 results in abrogation of tumor surveillance, th...

journal_title：Journal of cellular biochemistry

authors： Jeong HC,Gil NY,Lee HS,Cho SJ,Kim K,Chun KH,Cho H,Cha HJ

更新日期：2015-08-01 00:00:00

abstract：:The successful penetration of endothelial basement membranes is an important process in the formation of hematogenous tumor metastases. Heparan sulfate (HS) proteoglycan is a major constituent of endothelial basement membranes, and we have found that HS-degradative activities of metastatic B16 melanoma sublines correl...

journal_title：Journal of cellular biochemistry

authors： Nakajima M,Irimura T,Nicolson GL

更新日期：1988-02-01 00:00:00

abstract：:Using a yeast two-hybrid library screen, we have identified that the heart specific FHL2 protein, four-and-a-half LIM protein 2, interacted with human DNA-binding nuclear protein, hNP220. Domain studies by the yeast two-hybrid interaction assay revealed that the second LIM domain together with the third and the fourth...

journal_title：Journal of cellular biochemistry

authors： Ng EK,Chan KK,Wong CH,Tsui SK,Ngai SM,Lee SM,Kotaka M,Lee CY,Waye MM,Fung KP

更新日期：2002-01-01 00:00:00

abstract：:Madin-Darby canine kidney (MDCK) cells were previously shown to have few or no plasma membrane insulin binding sites (Hofmann et al: J Biol Chem 258:11774, 1983]. Accordingly, neither insulin-stimulated incorporation of [14C]glucose into glycogen, nor insulin-induced uptake of radiolabeled alpha-aminoisobutyrate ([3H]...

journal_title：Journal of cellular biochemistry

authors： Hofmann C,Crettaz M,Bruns P,Hessel P,Hadawi G

更新日期：1985-01-01 00:00:00

abstract：:Increasing evidence have proved that long noncoding RNAs (lncRNAs) play significant roles in tumorigenesis and development of various cancers. However, the effect of small nucleolar RNA host gene 20 (SNHG20) on the progression of esophageal squamous cell carcinoma (ESCC) remains to be discovered. Herein, we aim to fin...

journal_title：Journal of cellular biochemistry

authors： Zhang C,Jiang F,Su C,Xie P,Xu L

更新日期：2019-02-14 00:00:00

abstract：:In this study, we found that wounding of a confluent monolayer of squamous cell carcinoma (SCC) cells induced epithelial-mesenchymal transition (EMT) specifically at the edge of the wound. This process required the combined stimulation of TGFβ, TNFα, and PDGF-D. Such a combined cytokine treatment of confluent monolaye...

journal_title：Journal of cellular biochemistry

authors： Okui G,Tobiume K,Rizqiawan A,Yamamoto K,Shigeishi H,Ono S,Higashikawa K,Kamata N

更新日期：2013-09-01 00:00:00

abstract：:Due to the increasing incidence and mortality, the early diagnosis, specific targeted therapies, and prognosis for colorectal cancer (CRC) attract more and more attention. Wild-type p53-induced phosphatase 1 (Wip1) and karyopherin α2 (KPNA2) have been regarded as oncogenes in many cancers, including CRC. Wip1 dephosph...

journal_title：Journal of cellular biochemistry

authors： Wang P,Zhao Y,Liu K,Liu X,Liang J,Zhou H,Wang Z,Zhou Z,Xu N

更新日期：2019-09-01 00:00:00

abstract：:Cell proliferation requires the coordinate synthesis and degradation of many proteins. In addition to the well-characterized involvement of the proteasome in the degradation of several cell cycle-regulated proteins, it has been established that cysteine proteinases are also involved in the control of cell proliferatio...

journal_title：Journal of cellular biochemistry

authors： Torres C,Li M,Walter R,Sierra F

更新日期：2000-09-18 00:00:00

abstract：:In a human lymphoblastoid cell line (Z83) in which rDNA genes on chromosome 22 are amplified but transcribed at a low level, immunocytological studies with antibodies to 5 methylcytidine provided evidence for hypermethylation of the rDNA. The extent of methylation of the 5' flanking sequences of the ribosomal DNA was ...

journal_title：Journal of cellular biochemistry

authors： Dante R,Percy ME,Baldini A,Markovic VD,Miller DA,Rocchi M,Niveleau A,Miller OJ

更新日期：1992-12-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS), known as a common endocrine disorder among females, plagues many PCOS patients. The current study aimed to explore the correlations of sex hormone-binding globulin (SHBG) polymorphisms with the outcome of in vitro fertilization-embryo transfer (IVF-ET) in PCOS patients. PCOS patients ...

journal_title：Journal of cellular biochemistry

authors： Liu Y,Zhao XX,Hu XJ,Yang F,Lin P,Cui SC,Zhao W,Cao XY,Wang YS

更新日期：2019-03-01 00:00:00

abstract：:Up-regulation of cytosolic phospholipase A(2) (cPLA(2)) by cigarette smoke extract (CSE) may play a critical role in airway inflammatory diseases. However, the mechanisms underlying CSE-induced cPLA(2) expression in human tracheal smooth muscle cells (HTSMCs) were not completely understood. Here, we demonstrated that ...

journal_title：Journal of cellular biochemistry

authors： Cheng SE,Lin CC,Lee IT,Hsu CK,Kou YR,Yang CM

更新日期：2011-02-01 00:00:00

abstract：:Bladder cancer-associated transcript 1 (BLACAT1) is a novel identified long noncoding RNA (lncRNA) in bladder cancer, and has been suggested to function as an oncogenic lncRNA in several types of human cancer. However, its involvement in the progression of small-cell lung cancer (SCLC) remained unknown. The aim of our...

journal_title：Journal of cellular biochemistry

authors： Chen W,Hang Y,Xu W,Wu J,Chen L,Chen J,Mao Y,Song J,Song J,Wang H

更新日期：2018-09-11 00:00:00

abstract：:Deregulated proliferation of vascular smooth muscle cells (VSMCs) is one common phenomenon of atherosclerosis progression. Long noncoding RNAs (lncRNAs) are one group of noncoding RNAs that play essential roles in many cell biological processes, including cell development, growth, and migration. However, the role of a...

journal_title：Journal of cellular biochemistry

authors： Wang H,Jin Z,Pei T,Song W,Gong Y,Chen D,Zhang L,Zhang M,Zhang G

更新日期：2019-03-01 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a common disorder of unknown etiology. Studies have found a close relation between IBS and microRNAs (miRNAs), but the study concerning the relationship between IBS and miR-181c-5p in IBS is still blank. Thus, this study aims to explore the role of miR-181c-5p in IBS via interleukin 1...

journal_title：Journal of cellular biochemistry

authors： Ji LJ,Li F,Zhao P,Weng LP,Wei J,Yan J,Liu LN

更新日期：2019-09-01 00:00:00

abstract：:Growth and differentiation factor 7(GDF7), also later called as bone morphogenetic protein (BMP)12, is a new member of the BMP superfamily, which induces formation of tendon-like tissue formation in the ectopic implantation experiments. We examined the effect of BMP12 on proliferation and expression of phenotype-relat...

journal_title：Journal of cellular biochemistry

authors： Furuya K,Nifuji A,Rosen V,Noda M

更新日期：1999-02-01 00:00:00

abstract：:Chronic inflammation is a contributing factor to overall cancer risk as well as cancer promotion and progression; however, pathways regulating onset of cancer-promoting inflammatory responses are still poorly understood. Clinical data suggest that deficient anti-tumor cell-mediated immunity, in combination with enhanc...

journal_title：Journal of cellular biochemistry

authors： Johansson M,Tan T,de Visser KE,Coussens LM

更新日期：2007-07-01 00:00:00

abstract：:Extracts of serum-free conditioned medium from human rhabdomyosarcoma A673 cells contain high molecular weight (HMW) transforming growth factors (TGFs) that can be partially purified by Bio-Gel P-100 and carboxymethyl (CM)-cellulose chromatography (Todaro et al: Proc Natl Acad Sci USA 77:5258, 1980). Reverse-phase hig...

journal_title：Journal of cellular biochemistry

authors： Stromberg K,Hudgins WR,Fryling CM,Hazarika P,Dedman JR,Pardue RL,Hargreaves WR,Orth DN

更新日期：1986-01-01 00:00:00

abstract：:Multiple regulatory elements and intricate protein-DNA interactions mediate the transcription of the human histone H4 genes in a cell growth-dependent manner. Upon analysis of the regulatory elements of the FO108 histone H4 gene, we identified several potential YY1 binding sites. In this study, we have analyzed the ab...

journal_title：Journal of cellular biochemistry

authors： Last TJ,van Wijnen AJ,Birnbaum MJ,Stein GS,Stein JL

更新日期：1999-03-15 00:00:00

abstract：:We investigated the association of DNA polymerase and DNA primase activity with the nuclear matrix in HeLa S3 cells diluted with fresh medium after having been cultured without any medium change for 7 days. Flow cytometric analysis demonstrated that just before dilution about 85% of the cells were in the G1 phase of t...

journal_title：Journal of cellular biochemistry

authors： Martelli AM,Capitani S,Neri LM

更新日期：1998-10-01 00:00:00

abstract：:The P-glycoprotein (p170, P-gp) encoded by human MDR1 gene functions as a pump to extrude anticancer drugs from cancer cells. Over-expression of p170 is closely related to primary and induced drug resistance phenotype of tumor cells. Recent studies have demonstrated that expression of cyclooxygenase-2 (COX-2) is posit...

journal_title：Journal of cellular biochemistry

authors： Xia W,Zhao T,Lv J,Xu S,Shi J,Wang S,Han X,Sun Y

更新日期：2009-09-01 00:00:00

abstract：:The 17,180 base-pair Eco-RI-C fragment of Epstein-Barr virus has been sequenced in its entirety. This same fragment has also been analyzed for RNA polymerase II promoters, which are active in a soluble in vitro assay. These data are compared to the availability of predicted open reading frames and potential nucleotide...

journal_title：Journal of cellular biochemistry

authors： Deininger PL,Bankier A,Farrell P,Baer R,Barrell B

更新日期：1982-01-01 00:00:00

abstract：:Sepsis is usually accompanied by pulmonary inflammations, leading to acute lung injury. During this process, endogenous factors that play a regulatory role could be exploited to therapeutically alleviate such lethal tissue injury. Here, we showed that ulinastatin (UTI) administration could reduce lung tissue necrosis ...

journal_title：Journal of cellular biochemistry

authors： Wu J,Yan X,Jin G

更新日期：2018-09-22 00:00:00

abstract：:Multifidus muscle dysfunction is associated with the multifidus muscle injury (MMI), which ultimately result in the low-back pain. Increasing evidence shows that microRNAs (miRs) may be involved in multifidus muscle dysfunction. In this study, we tested the hypothesis that downregulation of let-7b-5p may inhibit the m...

journal_title：Journal of cellular biochemistry

authors： Yu HM,Yao XD,Zhang RM,Zhuang HF,Wang PW,Li YZ

更新日期：2018-11-01 00:00:00

abstract：:We have previously demonstrated that the antagonists of calmodulin (CaM) induce apoptosis of cholangiocarcinoma cells partially through Fas-mediated apoptosis pathways. Recently, CaM has been shown to bind to Fas, which is regulated during Fas or CaM antagonist-mediated apoptosis in Jurkat cells and osteoclasts. Accor...

journal_title：Journal of cellular biochemistry

authors： Chen Y,Pawar P,Pan G,Ma L,Liu H,McDonald JM

更新日期：2008-02-15 00:00:00

abstract：:Paxillin is an adapter protein regulating signaling and focal adhesion assembly that has been linked to malignant potential in many malignancies. Overexpression of paxillin has been noted in aggressive tumors. Integrin-mediated binding through the focal adhesion complex is important in metastatic adhesion and is upreg...

journal_title：Journal of cellular biochemistry

authors： Conway WC,Van der Voort van Zyp J,Thamilselvan V,Walsh MF,Crowe DL,Basson MD

更新日期：2006-08-15 00:00:00