Protein phosphorylation and the exocytosis-like interaction between isolated adrenal medullary plasma membranes and chromaffin granules.

abstract：:Tumour-secreted vascular endothelial growth factor (VEGF) exerts a number of effects which are important in tumour pathology, including stimulation of angiogenesis and permeabilisation of tumour-associated vasculature. In this study we have examined the possibility that VEGF may also play an autocrine role in tumour g...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Earl HM,Baban D,Shoaibi M,Fabra A,Kerr DJ,Seymour LW

更新日期：1995-12-26 00:00:00

abstract：:Ubiquitin C-terminal hydrolase-L3 (UCH-L3) is among the deubiquitinating enzymes (DUBs) that cleave ubiquitin (Ub) from Ub precursors or protein substrates. Many DUBs have been shown to participate in cancer progression in various tissues. However, the mechanism and role of UCH-L3 in carcinogenesis has largely been un...

journal_title：Biochemical and biophysical research communications

authors： Song HM,Lee JE,Kim JH

更新日期：2014-09-26 00:00:00

abstract：:Determination of the rates of saccharide diffusions by the proteoliposomes showed that the outer membrane of Pseudomonas aeruginosa only possesses small diffusion pores and that protein F might have not been involved in the pore formation. Proteoliposomes containing stachyose or Dextan T-10 showed the same relative di...

journal_title：Biochemical and biophysical research communications

authors： Yoshihara E,Gotoh N,Nakae T

更新日期：1988-10-14 00:00:00

abstract：:Prostasin is a glycosylphosphatidylinositol (GPI)-anchored serine protease and a suppressor of tumor cell invasion. We recently reported that the human prostasin gene is up-regulated by the transcription factor sterol regulatory element-binding protein-2 (SREBP-2). In the present study, we identified multiple SREBP-2 ...

journal_title：Biochemical and biophysical research communications

authors： Chen M,Chen LM,Chai KX

更新日期：2006-08-11 00:00:00

abstract：OBJECTIVE:To evaluate protein profiles and Fc gamma receptor IIb (FCGRIIB) expression in abdominal aortic aneurysm (AAA) compared to the expression in normal aortas. METHODS:We performed a protein array to study the protein expression profiles within AAA and normal aortic tissues. FCGRIIB was found to be significantly...

journal_title：Biochemical and biophysical research communications

authors： Shi Y,Yang CQ,Wang SW,Li W,Li J,Wang SM

更新日期：2017-04-01 00:00:00

abstract：:Jmjd2c is a candidate oncogene that encodes histone lysine demethylase. In this study, we discovered that over-expression of Jmjd2c increased the expression of Mdm2 oncogene dependent on its demethylase activity, which led to the reduction of p53 tumor suppressor gene product in the cells. A chromatin immunoprecipitat...

journal_title：Biochemical and biophysical research communications

authors： Ishimura A,Terashima M,Kimura H,Akagi K,Suzuki Y,Sugano S,Suzuki T

更新日期：2009-11-13 00:00:00

abstract：:The pattern of micrococcal nuclease digestion of chromatin from different organs of Allium cepa has been studied. The DNA from small oligonucleosomes appears to be highly degraded and heterogeneous. In solutions of intermediate ionic strength (0.15 M NaCl) histones H2A and H2B form dimers, however at high salt concent...

journal_title：Biochemical and biophysical research communications

authors： Moreno ML,Puigdomenech P,Palau J

更新日期：1985-06-28 00:00:00

abstract：:Previously we reported that the activity of protein kinase FA/glycogen synthase kinase-3alpha (kinase FA/GSK-3alpha) can be detected in several brain membrane fractions. In this report, we examined whether kinase FA/GSK-3alpha can directly interact with membrane phospholipids by using anti-kinase FA/GSK-3alpha antibod...

journal_title：Biochemical and biophysical research communications

authors： Yu JS,Chan WH,Yang SD

更新日期：1997-08-18 00:00:00

abstract：:Amphotericin B (AmB) is a potent antifungal agent used to treat patients with systemic mycoses. The cytotoxicity of AmB is related to its binding to membrane sterols and its clinical usefulness is based on its greater affinity to ergosterol, the fungal sterol, compared to the mammalian cell sterol, cholesterol (1-3). ...

journal_title：Biochemical and biophysical research communications

authors： Gruda I,Gauthier E,Elberg S,Brajtburg J,Medoff G

更新日期：1988-08-15 00:00:00

abstract：:Genomic DNA of the phytopathogenic Erwinia chrysanthemi PY35 was partially digested with Sau3AI, ligated into the BamHI site of pBluescript II SK+, and introduced into E. coli. One clone that was able to hydrolyse carboxymethylcellulose and polygalacturonic acid was selected. A 2.9 kb fragment containing the pelL1 gen...

journal_title：Biochemical and biophysical research communications

authors： Park SR,Kim MK,Kim JO,Bae DW,Cho SJ,Cho YU,Yun HD

更新日期：2000-02-16 00:00:00

abstract：:Expression of multidrug resistance-associated protein 2 (MRP2), an efflux pump contributing to biliary secretion of xenobiotics, was investigated in primary rat and human hepatocytes exposed to sulforaphane, a naturally-occurring chemopreventive agent. Northern blot indicated that sulforaphane increased MRP2 mRNA leve...

journal_title：Biochemical and biophysical research communications

authors： Payen L,Courtois A,Loewert M,Guillouzo A,Fardel O

更新日期：2001-03-23 00:00:00

abstract：:Evolution of a probable 'glutathione-binding ancestor' resulting in a common thioredoxin-fold for glutathione S-transferases and glutathione peroxidases may possibly suggest that a glutathione S-transferase could be engineered into a selenium-containing glutathione S-transferase (seleno-GST), having glutathione peroxi...

journal_title：Biochemical and biophysical research communications

authors： Jiang Z,Arnér ES,Mu Y,Johansson L,Shi J,Zhao S,Liu S,Wang R,Zhang T,Yan G,Liu J,Shen J,Luo G

更新日期：2004-08-13 00:00:00

abstract：:A 135kDa DNA polymerase alpha lacking primase activity has been purified to near homogeneity from Coprinus meiotic tissues. The activity of the DNA polymerase was sensitive to aphidicolin and N-ethylmaleimide, but was insensitive to dideoxythymidine triphosphate. DNA synthesis was proceeded with a low processivity. Ne...

journal_title：Biochemical and biophysical research communications

authors： Sawado T,Sakaguchi K

更新日期：1997-03-17 00:00:00

abstract：:In adrenalectomized rats, diacylglycerol, a potent activator of protein kinase C, specifically enhanced the induction of tyrosine aminotransferase and ornithine decarboxylase by even maximally effective doses of dexamethasone phosphate, but itself had no effect on these enzyme inductions in the absence of glucocortico...

journal_title：Biochemical and biophysical research communications

authors： Kido H,Fukusen N,Ishidoh K,Katunuma N

更新日期：1986-07-16 00:00:00

abstract：:SMRT acts as a corepressor for a range of transcription factors. The amino-terminal part of the protein includes domains that mainly mediate transcriptional repression whilst the carboxy-terminal part includes domains that interact with nuclear receptors using up to three motifs called CoRNR boxes. The region of the S...

journal_title：Biochemical and biophysical research communications

authors： Short S,Malartre M,Sharpe C

更新日期：2005-09-02 00:00:00

abstract：:We used fluorescence correlation spectroscopy (FCS) to study the activation of fibrinogen by thrombin and the subsequent aggregation of fibrin monomers into fibrin polymers at a very low and at physiological fibrinogen concentrations. In the labeling procedure used the fibrinogen was randomly labeled and the label was...

journal_title：Biochemical and biophysical research communications

authors： Bark N,Földes-Papp Z,Rigler R

更新日期：1999-06-24 00:00:00

abstract：:The enzymatic methylation of chemically alkylated DNA and of poly(dG-dC) X poly(dG-dC) by beef brain DNA(cytosine-5-)-methyltransferase have been tested. The alkylation by dimethylsulfate, which yields mostly 7 methylguanine (m7G) and 3 methyladenine (m3A) do not affect the enzymatic methylation. The dimethylsulfate a...

journal_title：Biochemical and biophysical research communications

authors： Pfohl-Leszkowicz A,Boiteux S,Laval J,Keith G,Dirheimer G

更新日期：1983-10-31 00:00:00

abstract：INTRODUCTION:SIRT2 is a NAD(+)-dependent deacetylases and associated with numerous processes such as infection, carcinogenesis, DNA damage and cell cycle regulation. However, the role of SIRT2 in inflammatory process in macrophage remains unclear. MATERIALS AND METHODS:In the present study, we have evaluated the regul...

journal_title：Biochemical and biophysical research communications

authors： Lee AS,Jung YJ,Kim D,Nguyen-Thanh T,Kang KP,Lee S,Park SK,Kim W

更新日期：2014-08-08 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders and is characterized by impaired attention, hyperactivity, and impulsivity. While multiple etiologies are implicated in ADHD, its underlying mechanism(s) remain unclear. Although previous studies have suggested dysre...

journal_title：Biochemical and biophysical research communications

authors： Nguyen Nguyen HT,Kato H,Sato H,Yamaza H,Sakai Y,Ohga S,Nonaka K,Masuda K

更新日期：2019-06-11 00:00:00

abstract：:Vibrio vulnificus, a halophilic estuarine bacterium causing a rapidly progressing fatal septicemia, is highly cytotoxic to eukaryotic cells. To identify new virulence factors associated with cytotoxicity, we constructed a mariner-based transposon (Tn Himar1) library of the highly virulent clinical isolate MO6-24/O hav...

journal_title：Biochemical and biophysical research communications

authors： Ran Kim Y,Haeng Rhee J

更新日期：2003-05-02 00:00:00

abstract：:Alveolar epithelial type I and type II cells (AEC I and II) are closely aligned in alveolar surface. There is much interest in the precise identification of AEC I and II in order to separate and evaluate functional and other properties of these two cells. This study aims to identify specific AEC I and AEC II cell mark...

journal_title：Biochemical and biophysical research communications

authors： Chen Z,Jin N,Narasaraju T,Chen J,McFarland LR,Scott M,Liu L

更新日期：2004-07-02 00:00:00

abstract：:Isolated rat cerebral cortex cells were able to accumulate L-carnitine and this process was competitively inhibited by 1 mM gamma-aminobutyric acid (GABA) with a shift of Km from 7.8 +/- 1.9 mM to 14.6 +/- 4.0 mM. Addition of GABA also affected distribution of carnitine derivatives. The decrease of acetylcarnitine lev...

journal_title：Biochemical and biophysical research communications

authors： Wawrzeńczyk A,Nałecz KA,Nałecz MJ

更新日期：1995-08-15 00:00:00

abstract：:We have classified microvesicles into two subtypes: larger MVs released upon stimulation of prostate cancer cells, sMVs, and smaller cMVs, released constitutively. cMVs are released as part of cell metabolism and sMVs, released at 10-fold higher levels, produced upon activation, including sublytic C5b-9. From electron...

journal_title：Biochemical and biophysical research communications

authors： Stratton D,Moore C,Antwi-Baffour S,Lange S,Inal J

更新日期：2015-05-08 00:00:00

abstract：:Glycogen phosphorylase in PC12 cells exists in two forms analogous to those found in brain and muscle. The active phosphorylated form of the enzyme, phosphorylase-a, represents about 20-30% of total glycogen phosphorylase in these cells. Incubation of PC12 cells with 100 ng 7S nerve growth factor/ml increased phosphor...

journal_title：Biochemical and biophysical research communications

authors： Davis LH,Kauffman FC

更新日期：1986-07-31 00:00:00

abstract：:We here report that aging increases expression of endothelin-1 and NO synthases in the vasculature and kidney of normotensive rats in vivo. Expression of preproendothelin-1 mRNA was quantified by RT-PCR and in situ hybridization, and endothelin-1 protein was determined by radioimmunoassay/HPLC. Vascular mRNA expressio...

journal_title：Biochemical and biophysical research communications

authors： Goettsch W,Lattmann T,Amann K,Szibor M,Morawietz H,Münter K,Müller SP,Shaw S,Barton M

更新日期：2001-01-26 00:00:00

abstract：:In the current study, we have examined the role of serotonin in regulating the levels of methyl farnesoate and ecdysteroids in the giant mud crab Scylla serrata and validated that serotonin indeed is a reproductive hormone. Administration of serotonin elevated circulatory levels of methyl farnesoate and ecdysteroids i...

journal_title：Biochemical and biophysical research communications

authors： Girish BP,Swetha CH,Reddy PS

更新日期：2017-09-02 00:00:00

abstract：:Botulinum neurotoxins (BoNTs) are produced as progenitor toxin complexes (PTCs) by Clostridium botulinum. The PTCs are composed of BoNT and non-toxic neurotoxin-associated proteins (NAPs), which serve to protect and deliver BoNT through the gastrointestinal tract in food borne botulism. HA33 is a key NAP component tha...

journal_title：Biochemical and biophysical research communications

authors： Lee K,Lam KH,Kruel AM,Perry K,Rummel A,Jin R

更新日期：2014-04-04 00:00:00

abstract：:Satellite cells are quiescent muscle stem cells that promote postnatal muscle growth and repair. When satellite cells are activated by myotrauma, they proliferate, migrate, differentiate, and ultimately fuse to existing myofibers. The remainder of these cells do not differentiate, but instead return to quiescence and ...

journal_title：Biochemical and biophysical research communications

authors： Nishimura T,Nozu K,Kishioka Y,Wakamatsu J,Hattori A

更新日期：2008-06-06 00:00:00

abstract：:The aminoglycoside antibiotic (AGA) neomycin is a known agonist of the extracellular calcium-sensing receptor (CaR). To test whether other AGA drugs stimulate the CaR, we studied the relative effects of four AGAs on intracellular Ca(2+) concentration ([Ca(2+)](i)) using CaR-transfected human embryonic kidney (HEK)-293...

journal_title：Biochemical and biophysical research communications

authors： McLarnon S,Holden D,Ward D,Jones M,Elliott A,Riccardi D

更新日期：2002-09-13 00:00:00

abstract：:By using a subtraction-enhanced display technique, we identified a cDNA clone representing alpha-prothymosin, from rat hepatocellular carcinoma (HCC). alpha-Prothymosin has been reported to be involved in cell proliferation and regulated by c-myc gene in vitro. In the present study, we investigated the gene expression...

journal_title：Biochemical and biophysical research communications

authors： Wu CG,Boers W,Reitsma PR,van Deventer SJ,Chamuleau RA

更新日期：1997-03-27 00:00:00