A clinical neuropathological study of the fetal alcohol syndrome.

Abstract:

:Five patients with the clinical diagnosis of fetal alcohol syndrome (FAS) died at the ages of 8 and 4 months and 17, 4 and 2 days. Neuropathological examination revealed microencephalic brains in all cases, without morphological evidence of maturation delay. One of them showed agenesis of the corpus callosum and hypoplasia of the cerebellar vermis. Five of them had only small dysgenetic changes, consisting mainly of glio or glioneuronal meningeal or parenchymal heterotopias. Our findings indicate that the brain is commonly but not affected in FAS. The influence of alcohol and its metabolites, as well as undernutrition, and use of other drugs by the mothers, should be taken into account as possible etiologic factors.

journal_name

Neuropediatrics

journal_title

Neuropediatrics

authors

Wisniewski K,Dambska M,Sher JH,Qazi Q

doi

10.1055/s-2008-1059578

subject

Has Abstract

pub_date

1983-11-01 00:00:00

pages

197-201

issue

4

eissn

0174-304X

issn

1439-1899

journal_volume

14

pub_type

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