Abstract:
:Five patients with the clinical diagnosis of fetal alcohol syndrome (FAS) died at the ages of 8 and 4 months and 17, 4 and 2 days. Neuropathological examination revealed microencephalic brains in all cases, without morphological evidence of maturation delay. One of them showed agenesis of the corpus callosum and hypoplasia of the cerebellar vermis. Five of them had only small dysgenetic changes, consisting mainly of glio or glioneuronal meningeal or parenchymal heterotopias. Our findings indicate that the brain is commonly but not affected in FAS. The influence of alcohol and its metabolites, as well as undernutrition, and use of other drugs by the mothers, should be taken into account as possible etiologic factors.
journal_name
Neuropediatricsjournal_title
Neuropediatricsauthors
Wisniewski K,Dambska M,Sher JH,Qazi Qdoi
10.1055/s-2008-1059578subject
Has Abstractpub_date
1983-11-01 00:00:00pages
197-201issue
4eissn
0174-304Xissn
1439-1899journal_volume
14pub_type
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