Persistence of naturally acquired cell-mediated immunity to rubella virus during the first trimester of pregnancy.

Abstract:

:We studied the persistence of naturally acquired cell-mediated immunity to rubella during early pregnancy. We compared lymphocyte transformation responses to phytohemagglutinin and rubella virus in 35 naturally immune women aged 17-37 years, in the first trimester of pregnancy, with 49 naturally immune age-matched nonpregnant controls. A significant lower lymphocyte transformation response to phytohemagglutinin was observed during the first trimester of pregnancy (P = 0.008), but lymphocyte transformation responses to rubella virus were not significantly different (P = 0.901). These data indicate that, in naturally immune women, cell-mediated immunity to rubella virus is not significantly altered by the physiological changes in early pregnancy.

journal_name

Can J Microbiol

authors

Rossier E,Phipps PH,Weber JM

doi

10.1139/m83-257

subject

Has Abstract

pub_date

1983-12-01 00:00:00

pages

1680-2

issue

12

eissn

0008-4166

issn

1480-3275

journal_volume

29

pub_type

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