Localization of phosphoprotein PP 105 in cell lines of various species.

abstract：:Beta-catenin has essential roles in morphogenesis and human cancer, both as a subunit of adhesive complexes in the cell membrane and as a transcriptional coactivator in the Wnt signaling pathway. In addition, beta-catenin also has the ability to transport lymphoid enhancer binding factor-1 into the nucleus. In this st...

journal_title：Biochemical and biophysical research communications

authors： Hsu HT,Liu PC,Ku SY,Jung KC,Hong YR,Kao C,Wang C

更新日期：2006-05-12 00:00:00

abstract：:The influence of retinoic acid on the incorporation of [1-14C]palmitic acid and [1-14C]arachidonic acid into phospholipids was examined in guinea pig peritoneal granulocytes. All-trans-retinoic acid inhibited the incorporation of both fatty acids into phosphatidic acid and phosphatidylinositol. However, it stimulated ...

journal_title：Biochemical and biophysical research communications

authors： Tou J

更新日期：1983-07-18 00:00:00

abstract：:2H-NMR spectroscopy has been used to study the distribution of 2H atoms in brain lactate, after intraperitoneal injection of 2H2O. Information on brain metabolism was obtained from the ratio [(3-2H) lactate]/[(2-2H)-lactate] which was found very sensitive to the PO2 in the breathing air. The dependence of this ratio o...

journal_title：Biochemical and biophysical research communications

authors： Vianello F,Scarpa M,Viglino P,Rigo A

更新日期：1997-08-28 00:00:00

abstract：:The nuclear receptors for heme, REV-ERBα and REV-ERBβ, play important roles in the regulation of metabolism and inflammation. Recently it was demonstrated that reduced REV-ERBα expression in hematopoetic cells in LDL receptor null mice led to increased atherosclerosis. We sought to determine if synthetic REV-ERB agoni...

journal_title：Biochemical and biophysical research communications

authors： Sitaula S,Billon C,Kamenecka TM,Solt LA,Burris TP

更新日期：2015-05-08 00:00:00

abstract：BACKGROUND:PTK6 is involved in cell proliferation, invasion and migration. Patients with lower PTK6 expression predicts poor prognosis of LSCC. However, the mechanism of PTK6 in LSCC progression remains unclear. We investigated the role of PTK6 in the pathogenesis of LSCC. METHODS:Human LSCC tissues and paired adjacen...

journal_title：Biochemical and biophysical research communications

authors： Wu D,Zhang X,Liu Z,Yan H,Mai J,Zhao Z,Zhong Q,Liu X

更新日期：2018-09-10 00:00:00

abstract：:Glycogen storage disease type Ia (GSD-Ia) is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC), a key enzyme in endogenous glucose production. This autosomal recessive disorder is characterized by impaired glucose homeostasis and long-term complications of hepatocellular adenoma/carcinoma (HCA/HCC)....

journal_title：Biochemical and biophysical research communications

authors： Cho JH,Kim GY,Mansfield BC,Chou JY

更新日期：2018-04-15 00:00:00

abstract：:We describe a method for the removal of endogenous troponin (Tn) complex from bundles of detergent-treated cardiac fibers. After 70 min treatment with cTnT-cTnI most of the endogenous Tn complex was removed from fiber bundles. Complete reconstitution of the Tn complex was achieved by reconstituting with cardiac tropon...

journal_title：Biochemical and biophysical research communications

authors： Chandra M,Kim JJ,Solaro RJ

更新日期：1999-09-16 00:00:00

abstract：:Infections with Pseudomonas aeruginosa (P. aeruginosa) are critical in ventilated and poly-traumatized patients. Most important, these bacteria cause frequent and chronic pulmonary infections in patients with cystic fibrosis. Therefore, identification of molecular mechanisms that mediate the infection of mammalian cel...

journal_title：Biochemical and biophysical research communications

authors： Kirschnek S,Adams C,Gulbins E

更新日期：2005-02-18 00:00:00

abstract：:During the course of a systematic non-targeting screening of peptide signal molecules in Hydra, we identified a novel myoactive neuropeptide called Hym-176. The primary structure of Hym-176 was determined to be APFIFPGPKVamide. It specifically and reversibly induced contraction of the ectodermal muscle of the hydra bo...

journal_title：Biochemical and biophysical research communications

authors： Yum S,Takahashi T,Koizumi O,Ariura Y,Kobayakawa Y,Mohri S,Fujisawa T

更新日期：1998-07-30 00:00:00

abstract：:Resveratrol (3,5,4'-trihydroxystilbene) is a naturally occurring phytoalexin, found in grapes and wine, which has been reported to exert a variety of important pharmacological effects. We have investigated the activity of resveratrol on proliferation and differentiation of the promyelocitic cell line HL-60. A concentr...

journal_title：Biochemical and biophysical research communications

authors： Ragione FD,Cucciolla V,Borriello A,Pietra VD,Racioppi L,Soldati G,Manna C,Galletti P,Zappia V

更新日期：1998-09-08 00:00:00

abstract：:The effects of etomoxir, an irreversible carnitine palmitoyltransferase I inhibitor, on the liver protein pattern and on liver morphology were examined by two-dimensional gel electrophoresis in female Sprague-Dawley rats treated with 125 mg/kg/day etomoxir for 28 days. In livers of treated animals a protein spot was f...

journal_title：Biochemical and biophysical research communications

authors： Steiner S,Wahl D,Mangold BL,Robison R,Raymackers J,Meheus L,Anderson NL,Cordier A

更新日期：1996-01-26 00:00:00

abstract：:miR-199b-5p is up-regulated significantly during the osteogenesis process in human bone marrow stromal cells (BMSCs). Inhibiting miR-199b-5p notably reduces while over-expressing miR-199b-5p promotes the BMSCs osteoblast differentiation, suggested by the alternations of osteogenic genes expression, ALP activity and th...

journal_title：Biochemical and biophysical research communications

authors： Zhao R,Li Y,Lin Z,Wan J,Xu C,Zeng Y,Zhu Y

更新日期：2016-09-02 00:00:00

abstract：:Helicobacter pylori is a pathogenic flagellated bacterium that infects the gastroduodenal mucosa and causes peptic ulcers in humans. FliD caps the distal end of the flagellar filament and is essential in filament growth. Moreover, FliD has been studied to diagnose and prevent H. pylori infection. Here, we report struc...

journal_title：Biochemical and biophysical research communications

authors： Cho SY,Song WS,Oh HB,Kim HU,Jung HS,Yoon SI

更新日期：2019-06-18 00:00:00

abstract：:A study was made of the effects of the venom of the Chilean spider Latrodectus mactans on endogenous ion-currents of Xenopus laevis oocytes. 1 microg/ml of the venom made the resting plasma membrane potential more negative in cells voltage-clamped at -60 mV. The effect was potentially due to the closure of one or seve...

journal_title：Biochemical and biophysical research communications

authors： Parodi J,Romero F,Miledi R,Martínez-Torres A

更新日期：2008-10-31 00:00:00

abstract：:The retinoblastoma tumor suppressor protein (RB) is inactivated in a majority of cancers. RB restricts cell proliferation by inhibiting the E2F family of transcription factors. The current model for RB/E2F function describes its role in regulating transcription at gene promoters. Whether the RB or E2F proteins might p...

journal_title：Biochemical and biophysical research communications

authors： Ahlander J,Bosco G

更新日期：2009-07-03 00:00:00

abstract：:Several rich sources of polyphenols stimulate the endothelial formation of nitric oxide (NO), a potent vasoprotecting factor, via the redox-sensitive activation of the PI3-kinase/Akt pathway leading to the phosphorylation of endothelial NO synthase (eNOS). The present study examined the molecular mechanism underlying ...

journal_title：Biochemical and biophysical research communications

authors： Auger C,Kim JH,Chabert P,Chaabi M,Anselm E,Lanciaux X,Lobstein A,Schini-Kerth VB

更新日期：2010-02-26 00:00:00

abstract：:Several studies have shown that transplantation of embryonic stem cells into diabetic animals either improved or normalized blood glucose levels. In this study, we examined the dose-dependent effect of early (prediabetic stage) intravenous administration of human umbilical cord blood (HUCB) mononuclear cells on blood ...

journal_title：Biochemical and biophysical research communications

authors： Ende N,Chen R,Reddi AS

更新日期：2004-12-17 00:00:00

abstract：:The protease, cancer procoagulant, was isolated from three murine metastatic tumors and was purified to apparent homogeneity (SDS-PAGE) from Lewis lung cells by the sequence of (NH4)2SO4 precipitation, DE-53 anion-exchange chromatography, and Sephacryl 200 chromatography. The murine tumor enzyme has a molecular weight...

journal_title：Biochemical and biophysical research communications

authors： Moore WR

更新日期：1992-04-30 00:00:00

abstract：:Molecular analysis of the induction of the lutropin/choriogonadotropin receptor during the process of luteinization of the rat ovary was performed. The appearance of receptor binding activity and an immunological analysis of the receptor using Triton solubilized membrane proteins show little receptor present in luteal...

journal_title：Biochemical and biophysical research communications

authors： Hansbury MJ,McIlroy PJ,Goldenthal MJ

更新日期：1990-09-14 00:00:00

abstract：BACKGROUND:Chronic myeloid leukemia (CML) is a type of cancer that starts in certain blood-forming cells of the bone marrow. LncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a well known protooncogene, has be shown to be upregulated in various tumor types, including multiple myeloma. However, the...

journal_title：Biochemical and biophysical research communications

authors： Wen F,Cao YX,Luo ZY,Liao P,Lu ZW

更新日期：2018-12-09 00:00:00

abstract：:Chironomus ramosus is known to tolerate high doses of gamma radiation exposure. Larvae of this insect possess more than 95% of hemoglobin (Hb) in its circulatory hemolymph. This is a comparative study to see effect of gamma radiation on Hb of Chironomus and humans, two evolutionarily diverse organisms one having extra...

journal_title：Biochemical and biophysical research communications

authors： Gaikwad PS,Panicker L,Mohole M,Sawant S,Mukhopadhyaya R,Nath BB

更新日期：2016-08-05 00:00:00

abstract：:Bone homeostasis is maintained by bone remodeling, which involves continuous bone resorption by osteoclasts and bone formation by osteoblasts. Dysregulation of bone turnover, caused by osteoclast overactivation, causes destructive bone diseases. However, the mechanisms underlying the maintenance of osteoclast differen...

journal_title：Biochemical and biophysical research communications

authors： Aoki S,Shimizu K,Ito K

更新日期：2020-07-05 00:00:00

abstract：:A calcium-calmodulin (Ca2(+)-CaM) stimulated histone H3 phosphorylating activity was identified as a component of a nuclear protein complex purified from a 150 mM NaCl extract of calf thymus chromatin. This activity bound to a CaM-Sepharose affinity column in a Ca2+ dependent manner and was eluted off the column in th...

journal_title：Biochemical and biophysical research communications

authors： Wakim BT,Picken MM,DeLange RJ

更新日期：1990-08-31 00:00:00

abstract：:The Fragile X protein FMRP is an RNA binding protein whose targets are not well known; yet, these RNAs may play an integral role in the disease's etiology. Using a biotinylated-FMRP affinity resin, we isolated RNAs from the parietal cortex of a normal adult that bound FMRP. These RNAs were amplified by differential di...

journal_title：Biochemical and biophysical research communications

authors： Sung YJ,Conti J,Currie JR,Brown WT,Denman RB

更新日期：2000-09-07 00:00:00

abstract：:Parathyroid hormone-related protein (PTHrP) is detected in many aggressive tumors and involved in malignant conversion; however, the underlying mechanism remains obscure. Here, we identified PTHrP as a mediator of epidermal growth factor receptor (EGFR) signaling to promote the malignancies of oral cancers. PTHrP mRNA...

journal_title：Biochemical and biophysical research communications

authors： Yamada T,Tsuda M,Ohba Y,Kawaguchi H,Totsuka Y,Shindoh M

更新日期：2008-04-11 00:00:00

abstract：:An endopeptidase capable of metabolizing a number of neuropeptides and generating [Met5] and [Leu5] enkephalin from enkephalin-containing peptides is secreted by glioma C6 cells. This neutral endopeptidase that is likely to be a thiol protease, has a Mr of 71KDa and is effective only towards oligopeptides. Its specifi...

journal_title：Biochemical and biophysical research communications

authors： Ferro ES,Tambourgi DV,Gobersztejn F,Gomes MD,Sucupira M,Armelin MC,Kipnis TL,Camargo AC

更新日期：1993-02-26 00:00:00

abstract：:The activity of neutral sphingomyelinase (EC 3.1.4.12) in a plasma membrane enriched fraction was found to be increased in dexamethasone treated cells. The elevation of sphingomyelinase activity was blocked by cycloheximide indicating that protein synthesis was required for the steroid action. Ceramidase (EC3.5.1.23) ...

journal_title：Biochemical and biophysical research communications

authors： Ramachandran CK,Murray DK,Nelson DH

更新日期：1990-03-16 00:00:00

abstract：:Cervical cancer is one of the most commonly diagnosed lethal malignancies among gynecological malignant tumors worldwide. Chemo-resistance is one of the key causal factors in cervical cancer death. Osthole (OST), a natural compound, exhibits various pharmacological activities, including anti-tumor effects. However, it...

journal_title：Biochemical and biophysical research communications

authors： Su J,Zhang F,Li X,Liu Z

更新日期：2019-06-25 00:00:00

abstract：:Lysophosphatidyl-L-serine (lysoPS) is thought to be an immunological regulator because it dramatically augments the degranulation of rat peritoneal mast cells (RPMCs). This stimulatory effect may be mediated by a lysoPS receptor, but its molecule has not been identified yet. During a ligand fishing study for the orpha...

journal_title：Biochemical and biophysical research communications

authors： Sugo T,Tachimoto H,Chikatsu T,Murakami Y,Kikukawa Y,Sato S,Kikuchi K,Nagi T,Harada M,Ogi K,Ebisawa M,Mori M

更新日期：2006-03-24 00:00:00

abstract：:Human platelets prelabeled with arachidonate exhibited a rapid and transient rise in arachidonoyl monoglyceride in addition to arachidonoyl diglyceride following thrombin stimulation. Substantial release of arachidonate and its metabolites also occurred at the early phase. Preincubation of labeled platelets with RHC 8...

journal_title：Biochemical and biophysical research communications

authors： Chau LY,Tai HH

更新日期：1983-05-31 00:00:00