Use of fibrin sealant in hypospadias surgical repair reduces the frequency of postoperative complications.

Abstract:

INTRODUCTION:Urethrocutaneous fistulas (UCF) and flap dehiscence (FD) are the most common postoperative complications after hypospadias (HS) surgical repair. The aim of this study was to evaluate whether the application of fibrin sealant over the site of surgery and suture lines reduces these complications. MATERIALS AND METHODS:A prospective cohort of consecutive patients was treated over a 3-year period. 30 patients were submitted to HS surgical repair plus application of fibrin glue over the suture line and surgical site; for comparison, another 56 subjects made up the control group which was submitted to surgical repair only. Variables assessed included: age, type of HS, fibrin sealant used, complications and number of surgical procedures required to treat recurrences. RESULTS:In general, the frequency of complications was 10 vs. 41% for UCF (p = 0.002), 13 vs. 50% for FD (p = 0.001), and for flap necrosis (FN) 6.7 vs. 28.6% (p = 0.01) for the treatment and control groups respectively. The number of surgical reinterventions to treat recurrences was higher in the control group than in the study group (p = 0.04). CONCLUSION:The incidence of UCF after HS surgical repair can be reduced by applying fibrin sealant over the site of surgery and the suture lines.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Ambriz-González G,Velázquez-Ramírez GA,García-González JL,de León-Gómez JM,Muciño-Hernández MI,González-Ojeda A,Basterra JV

doi

10.1159/000096932

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

37-41

issue

1

eissn

0042-1138

issn

1423-0399

pii

000096932

journal_volume

78

pub_type

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