Comparison of late changes in internal mammary artery and saphenous vein grafts in two consecutive series of patients 10 years after operation.

abstract：BACKGROUND:Early intervention with thrombolytic agents has been shown unequivocally to reduce mortality after acute myocardial infarction. Presently used agents have disadvantages such as short half-life, immunogenicity, hypotension, and bleeding complications. Therefore, there is a need to develop improved thrombolyti...

journal_title：Circulation

authors： Robinson JH,Browne MJ,Carey JE,Chamberlain PD,Chapman CG,Cronk DW,Dodd I,Entwisle C,Esmail AF,Kalindjian SB

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Hemodynamic efficiency of Fontan circulation is believed to be a major determinant of outcome. Prior research on flow dynamics in different modifications of Fontan circulation used in vitro models and computer-based simulation. This study was designed to compare in vivo flow dynamics in the systemic venous p...

journal_title：Circulation

authors： Be'eri E,Maier SE,Landzberg MJ,Chung T,Geva T

更新日期：1998-12-22 00:00:00

abstract：BACKGROUND:Bias in studies of preventive medications can occur when healthier patients are more likely to initiate and adhere to therapy than less healthy patients. We sought evidence of this bias by examining associations between statin exposure and various outcomes that should not be causally affected by statin expos...

journal_title：Circulation

authors： Dormuth CR,Patrick AR,Shrank WH,Wright JM,Glynn RJ,Sutherland J,Brookhart MA

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:Metabolic syndrome importantly accelerates the atherosclerotic process, the earliest event of which is endothelial dysfunction. Ghrelin, a gastric peptide with cardiovascular actions, has been shown to inhibit proatherogenic changes in experimental models. This study therefore investigated whether ghrelin ad...

journal_title：Circulation

authors： Tesauro M,Schinzari F,Iantorno M,Rizza S,Melina D,Lauro D,Cardillo C

更新日期：2005-11-08 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that several subsets of regulatory T cells that actively mediate immunologic tolerance play crucial roles in atherogenesis. Recently, orally administered anti-CD3 monoclonal antibody has been shown as an inducer of novel regulatory T cells expressing latency-associated peptide ...

journal_title：Circulation

authors： Sasaki N,Yamashita T,Takeda M,Shinohara M,Nakajima K,Tawa H,Usui T,Hirata K

更新日期：2009-11-17 00:00:00

abstract：:The healthcare system is undergoing a transition from paying for volume to paying for value. Clinicians, as well as public and private payers, are beginning to implement alternative delivery and payment models, such as the patient-centered medical home, accountable care organizations, and bundled payment arrangements....

journal_title：Circulation

authors： Bufalino VJ,Berkowitz SA,Gardner TJ,Piña IL,Konig M,AHA Expert Panel on Payment and Delivery System Reform.

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:Myocardial infarction (MI) is an ischemic wound that recruits millions of leukocytes. MI-associated blood leukocytosis correlates inversely with patient survival, yet the signals driving heightened leukocyte production after MI remain incompletely understood. METHODS AND RESULTS:With the use of parabiosis s...

journal_title：Circulation

authors： Sager HB,Heidt T,Hulsmans M,Dutta P,Courties G,Sebas M,Wojtkiewicz GR,Tricot B,Iwamoto Y,Sun Y,Weissleder R,Libby P,Swirski FK,Nahrendorf M

更新日期：2015-11-17 00:00:00

abstract：BACKGROUND:Despite the fact that nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated among patients with established cardiovascular disease, many receive NSAID treatment for a short period of time. However, little is known about the association between NSAID treatment duration and risk of cardiovascular d...

journal_title：Circulation

authors： Schjerning Olsen AM,Fosbøl EL,Lindhardsen J,Folke F,Charlot M,Selmer C,Lamberts M,Bjerring Olesen J,Køber L,Hansen PR,Torp-Pedersen C,Gislason GH

更新日期：2011-05-24 00:00:00

abstract：BACKGROUND:The countercurrent arrangement of capillary blood flow in the medulla of mammalian kidneys generates a gradient of oxygen tension between the renal cortex and the papillary tip that results in a state of relative hypoxia within the renal medulla. Exploration of the pathophysiological implications of medullar...

journal_title：Circulation

authors： Prasad PV,Edelman RR,Epstein FH

更新日期：1996-12-15 00:00:00

abstract：BACKGROUND:Endothelial progenitor cells (EPCs) circulate in adult peripheral blood (PB) and contribute to neovascularization. However, little is known regarding whether EPCs and their putative precursor, CD34-positive mononuclear cells (MNC(CD34+)), are mobilized into PB in acute ischemic events in humans. METHODS AND...

journal_title：Circulation

authors： Shintani S,Murohara T,Ikeda H,Ueno T,Honma T,Katoh A,Sasaki K,Shimada T,Oike Y,Imaizumi T

更新日期：2001-06-12 00:00:00

abstract：BACKGROUND:Several studies demonstrated ischemic microvascular damage in patients with acute myocardial infarction (AMI). In this study, myocardial contrast echocardiography (MCE) was used to assess the temporal changes in myocardial perfusion after reflow and to investigate the relation between MCE findings and myocar...

journal_title：Circulation

authors： Ito H,Iwakura K,Oh H,Masuyama T,Hori M,Higashino Y,Fujii K,Minamino T

更新日期：1995-02-01 00:00:00

abstract：:Six instances of sudden death were recorded by Holter monitoring, which showed ventricular fibrillation in five and a bradyarrhythmia in one. Complex ventricular ectopic activity preceded cardiac arrest in five patients, including the one with the bradyarrhythmic arrest. Two patients with chronic bifascicular block ar...

journal_title：Circulation

authors： Nikolic G,Bishop RL,Singh JB

更新日期：1982-07-01 00:00:00

abstract：:Twenty-four-hour ambulatory ECG recording was performed in 26 patients with variant angina to evaluate the diurnal distribution of ST-segment elevation in relation to chest pain and the incidence of arrhythmias during the episodes. During a recording period of 52 days, 364 ST-segment elevations of 1 mm or greater were...

journal_title：Circulation

authors： Araki H,Koiwaya Y,Nakagaki O,Nakamura M

更新日期：1983-05-01 00:00:00

abstract：:To determine whether real-time two-dimensional echocardiography (2-D echo) can estimate the extent of myocardial involvement in patients with acute myocardial infarction (MI), regional wall motion on serial short-axis 2-D echo recordings was analyzed and the summed scores were compared with estimates of infarct involv...

journal_title：Circulation

authors： Nixon JV,Narahara KA,Smitherman TC

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism can be a presenting symptom of cancer, but the association between lower limb arterial thrombosis and cancer is unknown. We therefore examined cancer risk and prognosis of cancer in patients with lower limb arterial thrombosis. METHODS:Using nationwide population-based Danish medical ...

journal_title：Circulation

authors： Sundbøll J,Veres K,Horváth-Puhó E,Adelborg K,Sørensen HT

更新日期：2018-08-14 00:00:00

abstract：:Using nondenaturing polyacrylamide gel electrophoresis, we have identified two distinct myosin isoenzymes in human atrial tissue that correspond to the V1 and V3 isomyosins found in rat ventricular tissue. Normal left and right atrial appendages have approximately 50% V3. When the left atrium was exposed to hemodynami...

journal_title：Circulation

authors： Buttrick PM,Malhotra A,Brodman R,McDermott L,Lam L

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Many clinical trials use composite end points to reduce sample size, but the relative importance of each individual end point within the composite may differ between patients and researchers. METHODS AND RESULTS:We asked 785 cardiovascular patients and 164 clinical trial authors to assign 25 "spending weigh...

journal_title：Circulation

authors： Stolker JM,Spertus JA,Cohen DJ,Jones PG,Jain KK,Bamberger E,Lonergan BB,Chan PS

更新日期：2014-10-07 00:00:00

abstract：BACKGROUND:Functional mitral regurgitation (MR) is caused by systolic traction on the mitral leaflets related to ventricular distortion. Little is known about whether chronic tethering causes the mitral leaflet area to adapt to the geometric needs imposed by tethering, in part because of inability to reconstruct leafle...

journal_title：Circulation

authors： Chaput M,Handschumacher MD,Tournoux F,Hua L,Guerrero JL,Vlahakes GJ,Levine RA

更新日期：2008-08-19 00:00:00

abstract：BACKGROUND:Despite recommendations in the guidelines and consensus documents, there has been no randomized controlled trial evaluating oral anticoagulation (OAC) alone without antiplatelet therapy (APT) in patients with atrial fibrillation and stable coronary artery disease beyond 1 year after coronary stenting. METHO...

journal_title：Circulation

authors： Matsumura-Nakano Y,Shizuta S,Komasa A,Morimoto T,Masuda H,Shiomi H,Goto K,Nakai K,Ogawa H,Kobori A,Kono Y,Kaitani K,Suwa S,Aoyama T,Takahashi M,Sasaki Y,Onishi Y,Mano T,Matsuda M,Motooka M,Tomita H,Inoko M,Wak

更新日期：2019-01-29 00:00:00

abstract：:Twenty adult patients with predominant mitral valve disease and variable degrees of tricuspid incompetence (TI) were reinvestigated 6-28 months after mitral valve operation. Postoperatively, 10 of the 20 patients were in sinus rhythm, compared with four of 20 preoperatively. Right ventricula peak systolic pressure dec...

journal_title：Circulation

authors： Simon R,Oelert H,Borst HG,Lichtlen PR

更新日期：1980-08-01 00:00:00

abstract：:Patency of the femoral artery of infants and children who previously had percutaneous arterial catheterization at a weight of less than 25 kg was studied angiographically. During the study period, 118 patients had repeat arterial catheterization. 48 from the opposite leg. Femoral artery occlusion was found in four pat...

journal_title：Circulation

authors： Hurwitz RA,Franken EA Jr,Girod DA,Smith JA,Smith WL

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells (MSCs) are bone marrow stromal cells that are in phase 1 clinical studies of cellular cardiomyoplasty. However, the electrophysiological effects of MSC transplantation have not been studied. Although improvement of ventricular function would represent a positive outcome of MSC transpla...

journal_title：Circulation

authors： Chang MG,Tung L,Sekar RB,Chang CY,Cysyk J,Dong P,Marbán E,Abraham MR

更新日期：2006-04-18 00:00:00

abstract：:From 1962-1977, 99 patients, mean age 65 +/- 0.5 years (range 60-81 years) underwent valve replacement for severe calcific aortic valve stenosis. Ninety-three percent of the patients were in New York Heart Association functional class III or IV. The aortic valve gradient was 76 +/- 3 mm Hg and the aortic valve area in...

journal_title：Circulation

authors： Murphy ES,Lawson RM,Starr A,Rahimtoola SH

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Experimental studies suggest that arterial injury and inflammation lead to increased neointimal growth after stenting. Despite the increased use of coronary stents in humans, there are only limited pathological data on the morphological features of in-stent restenosis. METHODS AND RESULTS:Detailed histology...

journal_title：Circulation

authors： Farb A,Weber DK,Kolodgie FD,Burke AP,Virmani R

更新日期：2002-06-25 00:00:00

abstract：:Many vasodilators have been tried as antianginal agents, but the reflex increase in sympathetic tone produced by these drugs necessitate their use with caution in patients with angina. In the first part of this study, captopril was given to 14 patients with angina and systolic arterial pressures of greater than 120 mm...

journal_title：Circulation

authors： Daly P,Mettauer B,Rouleau JL,Cousineau D,Burgess JH

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Although coronary thrombosis plays a critical role in the pathogenesis of unstable angina and non-Q-wave myocardial infarction (NQMI), the effects of thrombolytic therapy in these disorders is not clear. Also, the role of routine early coronary arteriography followed by revascularization has not been establi...

journal_title：Circulation

authors：

更新日期：1994-04-01 00:00:00

abstract：:Twenty-one patients with documented coronary atherosclerotic heart disease were studied to determine the effect of high dose oral isosorbide dinitrate (ISDN) on heart rate, blood pressure, and exercise time until angina pectoris. Patients were tested in two phases, initially with 0.4 mg of sublingual nitroglycerin and...

journal_title：Circulation

authors： Danahy DT,Burwell DT,Aronow WS,Prakash R

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Although beta-adrenergic receptor (AR) blockade therapy is beneficial in the treatment of heart failure, little is known regarding the transcriptional mechanisms underlying this salutary action. METHODS AND RESULTS:In the present study, we screened mice overexpressing Gsalpha, beta1AR, beta2AR, or protein k...

journal_title：Circulation

authors： Gaussin V,Tomlinson JE,Depre C,Engelhardt S,Antos CL,Takagi G,Hein L,Topper JN,Liggett SB,Olson EN,Lohse MJ,Vatner SF,Vatner DE

更新日期：2003-12-09 00:00:00

abstract：:Prognostic stratification was carried out on 518 patients less than or equal to 65 years of age who were discharged from the hospital following a definite or probable acute myocardial infarction and followed for four months. The total population was made up of 272 patients hospitalzed in 1973 and 246 patients hospital...

journal_title：Circulation

authors： Moss AJ,DeCamilla J,Davis H,Bayer L

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Oxidative stress activates endothelial innate immunity and disrupts endothelial functions, including endothelial nitric oxide synthase-derived nitric oxide bioavailability. Here, we postulated that oxidative stress induces sterol regulatory element-binding protein 2 (SREBP2) and microRNA-92a (miR-92a), which...

journal_title：Circulation

authors： Chen Z,Wen L,Martin M,Hsu CY,Fang L,Lin FM,Lin TY,Geary MJ,Geary GG,Zhao Y,Johnson DA,Chen JW,Lin SJ,Chien S,Huang HD,Miller YI,Huang PH,Shyy JY

更新日期：2015-03-03 00:00:00