Abstract：
:In this issue, Baumann et al. (2007) identify a helicase PICH that localizes to "threads" that remain connected between sister kinetochores after they have separated in anaphase. These threads are thought to be catenated centromeric DNA. PICH contributes to the mitotic checkpoint by recruiting Mad2 to kinetochores and is proposed to regulate checkpoint signaling by monitoring tension at centromeres.
journal_name
Celljournal_title
Cellauthors
Yen TJdoi
10.1016/j.cell.2006.12.022subject
Has Abstractpub_date
2007-01-12 00:00:00pages
20-1issue
1eissn
0092-8674issn
1097-4172pii
S0092-8674(06)01649-7journal_volume
128pub_type
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