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Evidence for an inherited predisposition to alcoholic pancreatitis. A controlled HLA typing study.

Abstract：

:To investigate the role of heredity in alcoholic pancreatitis, an HLA typing study has been performed. Patients with alcoholic pancreatitis exhibited an increased frequency of HLA Bw 39 when compared with the general population [13.6% vs 3.3%, P (corrected) less than 0.02; relative risk 4.7]. Alcoholics without pancreatitis did not differ from the general population with respect to HLA status, indicating that the increased incidence of HLA Bw 39 was related to alcoholic pancreatitis rather than to alcoholism itself. Thus, this study has provided evidence for a genetic predisposition to alcoholic pancreatitis.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

Wilson JS,Gossat D,Tait A,Rouse S,Juan XJ,Pirola RC

doi

10.1007/BF01312945

subject

Has Abstract

pub_date

1984-08-01 00:00:00

pages

727-30

issue

8

eissn

0163-2116

issn

1573-2568

journal_volume

29

pub_type

杂志文章

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