当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Changes in the term mouse placenta associated with maternal alcohol consumption and fetal growth deficits.

Changes in the term mouse placenta associated with maternal alcohol consumption and fetal growth deficits.

Abstract：

:Primiparous mice were fed alcohol in their drinking water as 0%, 10%, 15%, 20% (v/v) solutions on days 11 through 18 of gestation. Based on blood alcohol levels and on locomotor and health impairments, these treatment groups represent situations of mild, moderate, and severe alcohol abuse. There were significant alcohol-related fetal growth deficits but no increase in fetal mortality or malformation. Placental weight was reduced with increasing alcohol intake. Histologic examination of the placenta revealed an increase in the frequency and severity of intravascular coagulation of maternal erythrocytes in the labyrinth and advanced degenerative changes in the basal zone of alcohol-exposed placentas. These observations suggest that both the vascular and the endocrine functions of the placenta are compromised in alcohol-consuming dams.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Kennedy LA

doi

10.1016/0002-9378(84)90028-0

subject

Has Abstract

pub_date

1984-07-01 00:00:00

pages

518-22

issue

5

eissn

0002-9378

issn

1097-6868

pii

0002-9378(84)90028-0

journal_volume

149

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • Novel immunologic strategies in ovarian carcinoma.

    abstract：:The purpose of our study was to develop new biologic systems for the treatment or diagnosis of patients with ovarian carcinoma through expansion of T-cell lines from the tumor-infiltrating lymphocytes of patients with ovarian carcinoma in low-dose recombinant interleukin-2 in sufficient numbers for treatment and human...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/s0002-9378(11)91735-9

    authors： Freedman RS,Ioannides CG,Mathioudakis G,Platsoucas CD

    更新日期：1992-11-01 00:00:00

  • Elevated maternal levels of the long pentraxin 3 (PTX3) in preeclampsia and intrauterine growth restriction.

    abstract：OBJECTIVE:The prototypic long pentraxin pentraxin 3 is a new candidate marker for inflammatory conditions reflecting the involvement of the vascular bed. Endothelial dysfunction is a prominent feature of preeclampsia as a result of excessive maternal systemic inflammation. We investigated pentraxin 3 levels in preeclam...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2005.11.018

    authors： Cetin I,Cozzi V,Pasqualini F,Nebuloni M,Garlanda C,Vago L,Pardi G,Mantovani A

    更新日期：2006-05-01 00:00:00

  • Fetal cerebral, circulatory, and metabolic responses during heart rate decelerations with umbilical cord compression.

    abstract：OBJECTIVE:The purpose of this study was to determine the cerebral, circulatory, and metabolic responses of the ovine fetus near term to umbilical cord compression with variable-type fetal heart rate decelerations. STUDY DESIGN:Nine fetal sheep, at 0.9 of gestation, were studied before, during, and after umbilical cord...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(96)80027-5

    authors： Richardson BS,Carmichael L,Homan J,Johnston L,Gagnon R

    更新日期：1996-10-01 00:00:00

  • Should we really avoid giving oxygen to mothers with concerning fetal heart rate patterns?

    abstract：:We challenge a provocative article entitled "Oxygen for intrauterine resuscitation: of unproved benefit and potentially harmful" by Hamel et al in the August issue of the Journal. The authors contend there is no good evidence that oxygen administration to the mother of a fetus with a concerning fetal heart rate patter...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 评论,杂志文章

    doi：10.1016/j.ajog.2015.01.058

    authors： Garite TJ,Nageotte MP,Parer JT

    更新日期：2015-04-01 00:00:00

  • Association of cervical precancer with human papillomavirus types other than 16 among HIV co-infected women.

    abstract：BACKGROUND:HIV-seropositive women face high risk for infection with oncogenic human papillomavirus (oncHPV) types, abnormal Pap test results, and precancer, but cervical cancer risk is only modestly increased. Human papillomavirus (HPV)16 is highly oncogenic but only weakly associated with HIV status and immunosuppress...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ajog.2015.09.086

    authors： Massad LS,Xie X,Burk RD,D'Souza G,Darragh TM,Minkoff H,Colie C,Burian P,Palefsky J,Atrio J,Strickler HD

    更新日期：2016-03-01 00:00:00

  • Group B streptococci during pregnancy: a comparison of two screening and treatment protocols.

    abstract：OBJECTIVE:The objective was to evaluate whether the rate of neonatal group B streptococcal infection could be reduced by screening for group B streptococci during the third trimester of pregnancy. STUDY DESIGN:Two periods in which different screening and treatment protocols were applied were compared. In period A all ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(98)70063-8

    authors： Hafner E,Sterniste W,Rosen A,Schuchter K,Plattner M,Asboth F,Philipp K

    更新日期：1998-09-01 00:00:00

  • The use of standardized neonatal mortality ratios to assess the quality of perinatal care in Colorado.

    abstract：:Neonatal mortality in Colorado in the 3-year period 1977-1979 has been analyzed by means of standardized neonatal mortality ratios derived from birth weight-specific mortality for every obstetric facility. The standardized neonatal mortality ratios adjusted for the percentage of neonatal deaths due to untreatable diso...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(84)90447-2

    authors： Bowes WA Jr,Fryer GE Jr,Ellis B

    更新日期：1984-04-15 00:00:00

  • Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues.

    abstract：OBJECTIVE:Several recent reports have demonstrated the expression of luteinizing hormone-releasing hormone receptors by human ovarian and endometrial cancers. Controversy persists on the relevance of this finding, in particular whether these receptors mediate direct antiproliferative effects of luteinizing hormone-rele...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.119633

    authors： Völker P,Gründker C,Schmidt O,Schulz KD,Emons G

    更新日期：2002-02-01 00:00:00

  • Developmental regulation of the expression of 72 and 92 kd type IV collagenases in human trophoblasts: a possible mechanism for control of trophoblast invasion.

    abstract：OBJECTIVE:During early pregnancy fetal cytotrophoblast cells invade the uterus and penetrate the basement membrane, a property that is characteristic of malignant cells. However, unlike tumor invasion, trophoblast invasion of the uterus is under strict control. This control limits invasion, so that it primarily remains...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(94)90107-4

    authors： Shimonovitz S,Hurwitz A,Dushnik M,Anteby E,Geva-Eldar T,Yagel S

    更新日期：1994-09-01 00:00:00

  • Elevated urine thrombomodulin/creatinine ratio in severely preeclamptic pregnancies.

    abstract：:A relationship between the urine thrombomodulin/creatinine ratio and preeclampsia was investigated. Preeclamptic women had a higher urine thrombomodulin/creatinine ratio than did matched controls. However, significantly elevated urine thrombomodulin/creatinine ratios were found in severely, but not mildly, preeclampti...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(94)90111-2

    authors： Hsu CD,Lucas RB,Johnson TR,Hong SF,Chan DW

    更新日期：1994-09-01 00:00:00

  • Pregnancy-specific beta 1-glycoprotein as a prognostic indicator in complications of early pregnancy.

    abstract：:Pregnancy-specific beta 1-glycoprotein (SP-1) was measured by radioimmunoassay in patients admitted to the hospital with a clinical diagnosis of hemorrhage in early pregnancy. The results were compared with a normal range and were analyzed for their predictive value in determining prognosis. Six of the total study gou...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(80)90243-4

    authors： Ho PC,Jones WR

    更新日期：1980-10-01 00:00:00

  • Creatine kinase as a biochemical marker in diagnosis of placenta increta and percreta.

    abstract：:We describe 1 case of placenta increta and 1 of placenta percreta, both associated with elevated maternal serum creatine kinase concentration. In patients with placenta previa and ultrasonographic findings of an abnormally adherent placenta, an unexplained elevation in maternal serum creatine kinase level should alert...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(99)70683-6

    authors： Ophir E,Tendler R,Odeh M,Khouri S,Oettinger M

    更新日期：1999-04-01 00:00:00

  • The association between the absence of amniotic fluid bacterial inhibitory activity and intra-amniotic infection.

    abstract：:We studied the relationship of amniotic fluid bacterial inhibition in 50 patients with intra-amniotic infection to that in 50 matched control patients. Amniotic fluid was collected through a transcervical intrauterine catheter. All infected patients had clinical signs of intra-amniotic infection and greater than or eq...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(82)90004-7

    authors： Blanco JD,Gibbs RS,Krebs LF,Castaneda YS

    更新日期：1982-08-01 00:00:00

  • The enhanced production of placental interleukin-1 during labor and intrauterine infection.

    abstract：:The purpose of this study was to determine the effect of labor and chorioamnionitis in interleukin-1 production by human placenta. We studied the activity of the placenta to produce interleukin-1 with an enzyme immunoassay by culturing tissue blocks. The placental tissue obtained after labor produced a larger amount o...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(91)90241-i

    authors： Taniguchi T,Matsuzaki N,Kameda T,Shimoya K,Jo T,Saji F,Tanizawa O

    更新日期：1991-07-01 00:00:00

  • Unsuspected subclinical pregnancies in patients with luteal phase defects.

    abstract：:Patients with different types of luteal phase defects were studied with the use of the radioimmunoassay for the beta subunit of human chorionic gonadotropin (hCG) to determine if unsuspected subclinical pregnancies were more common in a particular type of defect. A type I luteal phase defect is always characterized by...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(16)33086-1

    authors： Cline DL

    更新日期：1979-06-15 00:00:00

  • The benefit of preterm birth at tertiary care centers is related to gestational age.

    abstract：OBJECTIVE:The purpose of this study was to examine the relationship between gestational age and outcomes of outborn versus inborn preterm infants. STUDY DESIGN:Multivariable logistic regression analysis was used to examine gestational age-specific, risk-adjusted outcomes of 2962 singleton infants who were born at <32 ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2003.139

    authors： Lee SK,McMillan DD,Ohlsson A,Boulton J,Lee DS,Ting S,Liston R

    更新日期：2003-03-01 00:00:00

  • Botulinum toxin: from life-threatening disease to novel medical therapy.

    abstract：:Botulinum toxin A is the newest therapy for the treatment of a variety of medical disorders caused by abnormalities of muscle activity. After successful use in other medical subspecialties, the newest applications of this potent neurotoxin are within the lower urinary tract. The toxin has evolved from a cause of fatal...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ajog.2006.03.108

    authors： Mahajan ST,Brubaker L

    更新日期：2007-01-01 00:00:00

  • Incidence of persistent birth injury in macrosomic infants: association with mode of delivery.

    abstract：OBJECTIVE:Our purpose was to determine the incidence of birth injury in a cohort of macrosomic infants (birth weight >4000 gm) and analyze the association between persistent injury and delivery method. STUDY DESIGN:Deliveries of 2924 macrosomic infants were reviewed. Outcomes were compared with those of 16,711 infants...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(97)70435-6

    authors： Kolderup LB,Laros RK Jr,Musci TJ

    更新日期：1997-07-01 00:00:00

  • Rapid determination of fetal lung maturity from infrared spectra of amniotic fluid.

    abstract：OBJECTIVE:The purpose of this study was to determine the feasibility of infrared spectroscopy as an alternative method for the prediction of fetal lung development. STUDY DESIGN:Samples of amniotic fluid were obtained by amniocentesis from 134 patients between the 26th and 41st week of pregnancy. To acquire infrared s...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(98)80006-9

    authors： Liu KZ,Dembinski TC,Mantsch HH

    更新日期：1998-02-01 00:00:00

  • Comparison of endometrial growth produced by unopposed conjugated estrogens or by micronized estradiol in postmenopausal women.

    abstract：OBJECTIVE:When unopposed estrogen replacement treatment is used, what is the pattern of endometrial growth? Does endometrial growth differ for various dosages and formulations? STUDY DESIGN:A total of 87 postmenopausal women, median age 57 years (mean 56.7 +/- 5.6 years, range 45 to 69 years), were studied in a prospe...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0002-9378(97)80022-1

    authors： Ettinger B,Bainton L,Upmalis DH,Citron JT,VanGessel A

    更新日期：1997-01-01 00:00:00

  • Epidemiology of miscarriage and its relation to other reproductive events in Finland.

    abstract：OBJECTIVE:This study investigates the occurrence of miscarriages over the reproductive life span of women in a population-based study. STUDY DESIGN:A questionnaire was sent in 1994 to a random sample of 3000 Finnish women aged 18 to 44 years (73% response rate). Age-adjusted percentages of women having had miscarriage...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(99)70568-5

    authors： Hemminki E,Forssas E

    更新日期：1999-08-01 00:00:00

  • Vaginal sonography versus serum human chorionic gonadotropin in early detection of pregnancy.

    abstract：:We first performed a vaginosonic scan and then determined the serum human chorionic gonadotropin (beta-hCG) concentration (Second International Standard) in 52 women at an early gestational age to establish criteria for the earliest possible identification of an intrauterine pregnancy by this new ultrasound technique....

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90039-7

    authors： Bernaschek G,Rudelstorfer R,Csaicsich P

    更新日期：1988-03-01 00:00:00

  • Effect of administration route and estrogen manipulation on endometrial uptake of Photofrin porfimer sodium.

    abstract：OBJECTIVE:Our purpose was to evaluate the influence of the route of drug administration and target tissue vascularity on the distribution of a photosensitizer, Photofrin porfimer sodium, in the uterus. STUDY DESIGN:The study was divided in two phases. In phase I 80 mature female rats were hormonally suppressed and the...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90517-m

    authors： Chapman JA,Tadir Y,Tromberg BJ,Yu K,Manetta A,Sun CH,Berns MW

    更新日期：1993-02-01 00:00:00

  • Second-look operations in ovarian cancer.

    abstract：:One hundred eighty-six patients with epithelial tumors of the ovary who were managed at the M. D. Anderson Hospital and Tumor Institute underwent an exploratory operation ("second-look" operation) to assess the status of the cancer. Fifty-eight patients were found to have no evidence of disease (NED) and chemotherapy ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(16)32778-8

    authors： Schwartz PE,Smith JP

    更新日期：1980-12-15 00:00:00

  • Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes.

    abstract：:We used the minimal model technique to obtain concurrent measurements of whole-body insulin sensitivity and pancreatic B-cell responsiveness to glucose during the third trimester of pregnancy. Insulin sensitivity in normal pregnant women (n = 8) was reduced to only one third that of a group of nonpregnant women (n = 7...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(90)91306-w

    authors： Buchanan TA,Metzger BE,Freinkel N,Bergman RN

    更新日期：1990-04-01 00:00:00

  • Increased inducibility of inflammatory mediators from peripheral blood mononuclear cells of women with salpingitis.

    abstract：:To investigate whether immune system activation may contribute to the tissue damage observed in salpingitis, we isolated peripheral blood mononuclear cells and quantitated production of the monocyte activation products tumor necrosis factor-alpha, interleukin-1, and interleukin-6. Unstimulated cells from 7 of 20 women...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(91)90316-j

    authors： Witkin SS,Toth M,Jeremias J,Ledger WJ

    更新日期：1991-09-01 00:00:00

  • Is Burch colposuspension ever cost-effective compared with tension-free vaginal tape for stress incontinence?

    abstract：OBJECTIVE:This study was undertaken to evaluate the cost-effectiveness of Burch colposuspension compared with tension-free vaginal tape. STUDY DESIGN:A Markov decision model was developed to compare costs (2005 US dollars) and effectiveness (quality-adjusted life years) of Burch and tension-free vaginal tape for stres...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2007.02.039

    authors： Wu JM,Visco AG,Weidner AC,Myers ER

    更新日期：2007-07-01 00:00:00

  • Catecholamine physiology in the ovine fetus. I. Gestational age variation in basal plasma concentrations.

    abstract：:Fifty-five ewes with chronically catheterized singleton gestations were studied to assess changes in basal concentrations of fetal catecholamines with increasing gestational age. All pregnancies were time dated, and measurements of catecholamines were conducted at least 5 days after placement of fetal catheters when f...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(84)90157-1

    authors： Palmer SM,Oakes GK,Lam RW,Oddie TH,Hobel CJ,Fisher DA

    更新日期：1984-06-15 00:00:00

  • Lack of aneuploidy for chromosomes 15, 16, and 18 in placentas from small-for-gestational-age liveborn infants.

    abstract：OBJECTIVE:The purpose of this study was to investigate the frequency of confined placental mosaicism (CPM) in placentas from liveborn infants. STUDY DESIGN:A retrospective analysis of 51 placentas from small-for-gestational-age (SGA), live born infants (birthweight below 5th centile), and 45 placentas from normally gr...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2007.08.027

    authors： Papadogiannakis N,Iwarsson E,Taimi T,Zaphiropoulos PG,Westgren M

    更新日期：2008-02-01 00:00:00

  • Predictive value of early pregnancy glycohemoglobin in the insulin-treated diabetic patient.

    abstract：:The influence of early pregnancy glycemic control as measured by hemoglobin A1c concentration and the incidence of congenital anomalies and spontaneous abortions were evaluated in women presenting for prenatal care with insulin-treated diabetes in a population whose glycemic control was poor. Thirty-one abnormal outco...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(87)90117-7

    authors： Key TC,Giuffrida R,Moore TR

    更新日期：1987-05-01 00:00:00