Abstract:
:The effect of varying dietary levels of zinc was evaluated in mice fed T-2 toxin. A semipurified diet was used to produce a low zinc (less than 2 parts per million (ppm], a zinc replete (100 ppm), and a high zinc (2500 ppm) diet. T-2 toxin was added to the three zinc diets at a concentration of 10 ppm. The mice were fed one of the six diets ad libitum for up to 28 days. Mice from each diet were submitted for necropsy after 14 and 28 days and after 14 days zinc absorption and retention was measured in mice from each of the low and replete zinc diets, with and without T-2 toxin. Animals receiving a low zinc diet with T-2 toxin had reduced weight gains. The high zinc diet did not depress growth and did not influence T-2 depression of growth. The diets produced significant hematological changes without evidence of a T-2 toxin - zinc interaction. While zinc absorption was greater in mice fed the low zinc diet than those fed the replete zinc diet, T-2 toxin decreased absorption of zinc in the low zinc group and increased absorption in the replete zinc group. T-2 toxin did not influence the biological half-life of retained zinc in either the low or replete zinc groups. The biological half-life of zinc was significantly increased in the mice fed the low zinc diet relative to the replete zinc diet.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Can J Physiol Pharmacoljournal_title
Canadian journal of physiology and pharmacologyauthors
Chanin BE,Hamilton DL,Hancock DS,Schiefer HBdoi
10.1139/y84-221subject
Has Abstractpub_date
1984-10-01 00:00:00pages
1320-6issue
10eissn
0008-4212issn
1205-7541journal_volume
62pub_type
杂志文章abstract::Natural rodent grooming and other instinctive behavior serves as a natural model of complex movement sequences. Rodent grooming has syntactic (rule-driven) sequences and more random movement patterns. Both incorporate the same movements--only the serial structure differs. Recordings of neural activity in the dorsolate...
journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y04-061
更新日期:2004-08-01 00:00:00
abstract::Cyclic AMP formation from ATP was stimulated by unpurified and partially purified soluble hepatic guanylate cyclase in the presence of nitric oxide (NO) or compounds containing a nitroso moiety such as nitroprusside, N-methyl-N-nitro-N-nitrosoguanidine (MNNG), nitrosyl ferroheme, and S-nitrosothiols. Cyclic AMP format...
journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y80-219
更新日期:1980-12-01 00:00:00
abstract::The adenylate cyclase activity induced by norepinephrine (10(-8)-10(-9) M) was studied in hypothalamic particulate fractions from female rats. The effect of estradiol on this activity was studied in rats that were ovariectomized in diestrus 1, injected with estradiol benzoate (50 micrograms/kg body weight), and killed...
journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
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更新日期:1994-11-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y78-082
更新日期:1978-06-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
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更新日期:1990-07-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y78-039
更新日期:1978-04-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y10-111
更新日期:2011-02-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
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更新日期:2005-08-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章,评审
doi:10.1139/y86-151
更新日期:1986-07-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章,评审
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更新日期:2011-08-01 00:00:00
abstract::The effects of haloperidol, an antipsychotic butyrophenone, on excitability and action potential production in frog's sartorius muscle fibers were studied. This drug produced a local-anestheticlike effect which developed slowly over 1 to 5 h with lower concentrations (2.7 to 5.3 X 10(-6 M) but was completely reversed ...
journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y77-066
更新日期:1977-06-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y80-006
更新日期:1980-01-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y83-212
更新日期:1983-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1139/cjpp-77-1-75
更新日期:1999-01-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y79-038
更新日期:1979-03-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y82-166
更新日期:1982-09-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y83-198
更新日期:1983-11-01 00:00:00
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更新日期:2010-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:1985-07-01 00:00:00
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更新日期:2004-11-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y92-170
更新日期:1992-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1139/y88-189
更新日期:1988-09-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y83-136
更新日期:1983-08-01 00:00:00
abstract::To determine if increased endometrial vascular permeability (a response which precedes decidualization) could be obtained in temporally nonsensitized uteri by treatments designed to increase endometrial adenosine 3':5'-cyclic monophosphate (cAMP) concentrations, cholera toxin (an activator of adenylate cyclase) was in...
journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
doi:10.1139/y85-172
更新日期:1985-09-01 00:00:00
abstract::In vivo fatty acid synthesis and the pathways of glycerol-3-phosphate (G3P) production were investigated in brown adipose tissue (BAT) from rats fed a cafeteria diet for 3 weeks. In spite of BAT activation, the diet promoted an increase in the carcass fatty acid content. Plasma insulin levels were markedly increased i...
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更新日期:2008-07-01 00:00:00
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更新日期:2002-03-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
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更新日期:1987-07-01 00:00:00
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journal_title:Canadian journal of physiology and pharmacology
pub_type: 杂志文章
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更新日期:1979-01-01 00:00:00