Neurite outgrowth of neuroblastoma cells induced by proteins covalently coupled to glass coverslips.

Abstract:

:A method using proteins covalently coupled to glass surfaces has been applied to studies on the differentiation of neuroblasts. Neuroblastoma cells from clones N 18 and NIE 115 adhere to surfaces coated with fibronectin or laminin and extend rapidly growth cone-containing neurites. Some lectin-coated surfaces are also able to support neurite outgrowth, although the activities are lower than those of fibronectin and laminin. We discuss the biochemical requirements of the surface structures capable of inducing a differentiated neuronal morphology to neuroblastoma cells, and also consider the possible relationship of the results to physiological differentiation phenomena.

journal_name

Eur J Cell Biol

authors

Jousimaa J,Merenmies J,Rauvala H

subject

Has Abstract

pub_date

1984-09-01 00:00:00

pages

55-61

issue

1

eissn

0171-9335

issn

1618-1298

journal_volume

35

pub_type

杂志文章
  • The COP9 signalosome and its role in plant development.

    abstract::The COP9 signalosome (CSN) is an evolutionarily conserved multiprotein complex with a role in the regulation of cullin-RING type E3 ubiquitin ligases (CRLs). CSN exerts its function on E3 ligases by deconjugating the ubiquitin-related protein NEDD8 from the CRL cullin subunit. Thereby, CSN has an impact on multiple CR...

    journal_title:European journal of cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejcb.2009.11.021

    authors: Schwechheimer C,Isono E

    更新日期:2010-02-01 00:00:00

  • Is there a pilot in a pseudopod?

    abstract::The concept of pilot pseudopodia is reconsidered 30 years after its inauguration (Gerisch, G., Hülser, D., Malchow, D., Wick, U., 1975. Cell communication by periodic cyclic-AMP pulses. Phil. Trans. R. Soc. Lond. B 272, 181-192). The original hypothesis stated that protruding pseudopodia serve as dynamic sensory organ...

    journal_title:European journal of cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejcb.2006.05.002

    authors: Weber I

    更新日期:2006-09-01 00:00:00

  • Centrosome structure and function is altered by chloral hydrate and diazepam during the first reproductive cell cycles in sea urchin eggs.

    abstract::This paper explores the mode of action of the tranquillizers chloral hydrate and diazepam during fertilization and mitosis of the first reproductive cell cycles in sea urchin eggs. Most striking effects of these drugs are the alteration of centrosomal material and the abnormal microtubule configurations during exposur...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1016/S0171-9335(98)80041-1

    authors: Schatten H,Chakrabarti A

    更新日期:1998-01-01 00:00:00

  • Programmed cell death in C. elegans, mammals and plants.

    abstract::Programmed cell death (PCD) is the regulated removal of cells within an organism and plays a fundamental role in growth and development in nearly all eukaryotes. In animals, the model organism Caenorhabditis elegans (C. elegans) has aided in elucidating many of the pathways involved in the cell death process. Various ...

    journal_title:European journal of cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejcb.2012.02.002

    authors: Lord CE,Gunawardena AH

    更新日期:2012-08-01 00:00:00

  • Peroxisomes in digestive gland cells of the mussel Mytilus galloprovincialis Lmk. Biochemical, ultrastructural and immunocytochemical characterization.

    abstract::The present study was undertaken because of the paucity of information on peroxisomes in molluscs and the increasing importance of these organisms as sensitive indicators of environmental pollution. Peroxisomes were identified by electron microscopy in all three main cell types of the digestive gland of the bivalve mo...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Cajaraville MP,Völkl A,Fahimi HD

    更新日期:1992-12-01 00:00:00

  • LIM kinase 1: evidence for a role in the regulation of intracellular vesicle trafficking of lysosomes and endosomes in human breast cancer cells.

    abstract::LIM kinase (LIMK) plays a critical role in stimulus-induced remodeling of the actin cytoskeleton by linking signals from the Rho family GTPases to changes in cofilin activity. Recent studies have shown an important role for LIMK1 signaling in tumor cell invasion through regulating actin dynamics. In this study, we inv...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1078/0171-9335-00382

    authors: Nishimura Y,Yoshioka K,Bernard O,Himeno M,Itoh K

    更新日期:2004-08-01 00:00:00

  • Localization of a centrin-like protein to higher plant plasmodesmata.

    abstract::Antibodies against centrin, the ubiquitous calcium-binding contractile protein, recognized a 17 kDa protein in extracts of onion root tips and cauliflower florets. Using immunofluorescence microscopy, anti-centrin antibodies were localized to the developing cell plate of onion and cauliflower root tip cells. In caulif...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1016/S0171-9335(99)80063-6

    authors: Blackman LM,Harper JD,Overall RL

    更新日期:1999-05-01 00:00:00

  • Microtubule and centrosome distribution during sheep fertilization.

    abstract::The distribution of microtubules and centrosomes was studied during sheep fertilization by electron and immunofluorescence microscopy. Tubulin and centrosomal material was identified with monoclonal anti-alpha-tubulin and MPM-2 antibodies, respectively. In ovulated eggs, microtubules were exclusively found in the meio...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Le Guen P,Crozet N

    更新日期:1989-04-01 00:00:00

  • The influence of differential processing of procathepsin H on its aminopeptidase activity, secretion and subcellular localization in human cell lines.

    abstract::Cathepsin H is a unique member of the cysteine cathepsins that acts primarily as an aminopeptidase. Like other cysteine cathepsins, it is synthesized as an inactive precursor and activated by proteolytic removal of its propeptide. Here we demonstrate that, in human cells, the processing of the propeptide is an autocat...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1016/j.ejcb.2012.05.004

    authors: Rojnik M,Jevnikar ZR,Doljak B,Turk S,Zidar N,Kos J

    更新日期:2012-10-01 00:00:00

  • Regulation of the maize (Zea mays L.) embryo proteome by RTCS which controls seminal root initiation.

    abstract::Seminal roots are initiated at the scutellar node during maize (Zea mays L.) embryo development. The maize mutant rtcs (rootless concerning crown and seminal roots) does not initiate seminal roots while its wild-type siblings form on average 2.9 seminal roots per seedling. In this study, proteome profiles of 25-day-ol...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1016/j.ejcb.2009.11.014

    authors: Muthreich N,Schützenmeister A,Schütz W,Madlung J,Krug K,Nordheim A,Piepho HP,Hochholdinger F

    更新日期:2010-02-01 00:00:00

  • Sorting out the multiple roles of Fas ligand.

    abstract::Fas ligand can both be used by the immune system to initiate cell death, and be used by non-lymphoid cells to evade death. Recent work has shown that Fas ligand is differentially sorted in different cell types. Here we present the viewpoint that the differential sorting plays an important part in determining the role ...

    journal_title:European journal of cell biology

    pub_type: 杂志文章,评审

    doi:10.1078/0171-9335-00077

    authors: Bossi G,Stinchcombe JC,Page LJ,Griffiths GM

    更新日期:2000-08-01 00:00:00

  • Evidence for the presence of proteolytic activity in peroxisomes.

    abstract::The presence of endo- and exoproteolytic activity in peroxisomes was detected in cell organelles purified from pea leaves. By PAGE using different exopeptidase substrates (L-aa-beta NA), one leucine aminopeptidase (AP) was found in peroxisomes. The peroxisomal AP was characterized as a serine protease and had a maxima...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Corpas FJ,Palma JM,del Río LA

    更新日期:1993-06-01 00:00:00

  • Trophic effect of insulin-like growth factor-I on metanephric development: relationship to proteoglycans.

    abstract::Many hormones/factors influence the total body growth and development during embryonic life, and very few studies have been carried out to ascertain their effects on the individual organ system. In this study, the effect of exogenous insulin-like growth factor-I (IGF-I) on embryonic kidneys was investigated, and corre...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Liu ZZ,Kumar A,Wallner EI,Wada J,Carone FA,Kanwar YS

    更新日期:1994-12-01 00:00:00

  • Retention of the fetoacinar pancreatic (FAP) protein to the endoplasmic reticulum of tumor cells.

    abstract::The fetoacinar pancreatic (FAP) protein is a specific component of the human exocrine pancreas associated with the differentiation and proliferation of acinar cells. FAP expression is enhanced in cases of pancreatic exocrine cancer and it is found in relatively high concentrations in pathological pancreatic juices. Ho...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Miralles F,Langa F,Mazo A,Escribano MJ

    更新日期:1993-02-01 00:00:00

  • The effect of energy deprivation and hyperosmolarity upon tubular structures and electrophysiological parameters of muscle fibres.

    abstract::The exhaustion of metabolically poisoned muscle fibres is accompanied by a one hundred-fold increase in potassium conductance. Under these conditions a normal membrane capacity was measured. Extracellular markers (lanthanum, ferritin) were traced in the transverse tubular system but not in the myoplasm or the sarcopla...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Fink R,Grocki K,Lüttgau HC

    更新日期:1980-04-01 00:00:00

  • Electron microscopic study of eukaryotic 40S initiation complex in protein synthesis.

    abstract::This electron microscopic study demonstrates that formation of a functional eukaryotic 40S initiation complex is accompanied by conformational changes which obscure the characteristic structural features of the 40S ribosomal subunits and of the initiation factor eIF-3, the only macromolecular components of the complex...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Boublik M,Hellmann W,Staehelin T,Trachsel H

    更新日期:1983-11-01 00:00:00

  • Distribution of sulfated glycosaminoglycans in the glomerular basement membrane and mesangial matrix.

    abstract::The relative distribution of heparan sulfate-glycosaminoglycan (HS-GAG) and chondroitin sulfate-glycosaminoglycans (CS-GAG) of the mesangial matrix (MM) and the glomerular basement membrane (GBM), which represent the two glomerular extracellular matrices, was determined by a combination of enzymatic treatments and aut...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Kanwar YS,Jakubowski ML,Rosenzweig LJ

    更新日期:1983-09-01 00:00:00

  • Filensin is proteolytically processed during lens fiber cell differentiation by multiple independent pathways.

    abstract::Filensin is a lens-specific intermediate filament protein, expressed in the lens fiber cells but not the lens epithelium. Using antibodies to filensin and the other lens intermediate filament proteins, vimentin and CP49, the codistribution of filensin with CP49 and independence of this network from the vimentin networ...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Sandilands A,Prescott AR,Hutcheson AM,Quinlan RA,Casselman JT,FitzGerald PG

    更新日期:1995-07-01 00:00:00

  • Characterization of proteins secreted during maize microspore culture: arabinogalactan proteins (AGPs) stimulate embryo development.

    abstract::To study molecules secreted from cultured plant cells that promote development, maize microspores were transferred into culture and the conditioned media were collected over time and analysed. Electrophoresis indicated that both non-glycosylated and glycosylated proteins including arabinogalactan proteins (AGPs) appea...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1078/0171-9335-00378

    authors: Borderies G,le Béchec M,Rossignol M,Lafitte C,Le Deunff E,Beckert M,Dumas C,Elisabeth MR

    更新日期:2004-07-01 00:00:00

  • Rho GTPase signaling in Dictyostelium discoideum: insights from the genome.

    abstract::Rho GTPases are ubiquitously expressed across the eukaryotes where they act as molecular switches participating in the regulation of many cellular processes. We present an inventory of proteins involved in Rho-regulated signaling pathways in Dictyostelium discoideum that have been identified in the completed genome se...

    journal_title:European journal of cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejcb.2006.04.011

    authors: Vlahou G,Rivero F

    更新日期:2006-09-01 00:00:00

  • Structure, synthesis, and orientation of microfibrils. IX. A freeze-fracture investigation of the Oocystis plasma membrane after inhibitor treatments.

    abstract::Cells of Oocystis solitaria after treatment with inhibitors of a) microfibril orientation b) microfibril synthesis, and c) microfibril crystallization have been investigated with the freeze-fracturing technique. Changes in morphology of the E-face of the plasma membrane as a result of these treatments have been record...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Robinson DG,Quader H

    更新日期:1981-10-01 00:00:00

  • Thymosin beta 4 (T beta 4) in activated platelets.

    abstract::When resting human blood platelets are stimulated with thrombin, 50 to 60% of the G-actin polymerizes to F-actin within 60 seconds. The increase in F-actin is correlated with a corresponding decrease in the complex of G-actin with T beta 4. Within 5 seconds after stimulation, nucleation sites for pyrene actin polymeri...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Nachmias VT,Cassimeris L,Golla R,Safer D

    更新日期:1993-08-01 00:00:00

  • Heterogeneity of the zymogen granule membranes in rat pancreas.

    abstract::Zymogen granules (ZG) of rat pancreas have been isolated by the procedure of Pâquet et al. The granules lysed when exposed to alkaline pH (pH 8.2), and their membranes could be subfractionated by centrifugation on a sucrose gradient. Four discrete types of membranes corresponding to densities of 1.105, 1.085, 1.075, a...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Beaudoin AR,Gilbert L,St-Jean P,Grondin G,Cabana C

    更新日期:1988-12-01 00:00:00

  • Phosphorylation of p97(VCP) and p47 in vitro by p34cdc2 kinase.

    abstract::The hexameric ATPase p97/yeast Cdc48p has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. p97/Cdc48p contains two conserved consensus p34cdc2 kinase phosphorylation sites with...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1016/S0171-9335(99)80055-7

    authors: Mayr PS,Allan VJ,Woodman PG

    更新日期:1999-04-01 00:00:00

  • Association between cytoskeletal microtubules and Ca2+-sequestering smooth ER in Semper cells of fly ommatidia.

    abstract::The Semper cells in the ommatidia of the blowfly contain an impressive cytoskeleton consisting of hundreds of microtubules. The microtubules are intimately interwoven by an extensive system of the smooth endoplasmic reticulum. The cells were permeabilized by saponin treatment, subsequently incubated in a loading mediu...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Walz B

    更新日期:1983-11-01 00:00:00

  • The coincident distribution of calcium-rich membranes and kinetochore fibers at metaphase in living endosperm cells of Haemanthus.

    abstract::We have coupled chlorotetracycline (CTC) fluorescence with polarized light microscopic observations of living mitotic endosperm cells of Haemanthus in order to compare the spatial distributions of Ca2+-rich endomembranes in the spindle with that of the kinetochore fibers during metaphase. In either control cells or in...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Wolniak SM,Hepler PK,Jackson WT

    更新日期:1981-08-01 00:00:00

  • Carbonic anhydrase XII promotes invasion and migration ability of MDA-MB-231 breast cancer cells through the p38 MAPK signaling pathway.

    abstract::Carbonic anhydrase (CA) XII, an extracellular enzyme involved in the regulation of the microenvironment acidity and tumor malignant phenotype, was originally identified as a protein overexpressed in some types of cancers, including breast cancer. However, the cellular function and mechanism of CAXII remained unclear. ...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1016/j.ejcb.2010.03.004

    authors: Hsieh MJ,Chen KS,Chiou HL,Hsieh YS

    更新日期:2010-08-01 00:00:00

  • Helically twisted filaments in giant neurons of a whip spider.

    abstract::In giant neurons of whip spider legs several filament types are detectable: filaments of 5 to 6 nm thickness as dense masses within the soma of the neuron, an intermediate-sized filament type limited to the dendritic processes forming irregularly wound bundles and finally twisted double filaments in the soma as well a...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Foelix RF,Hauser M

    更新日期:1979-08-01 00:00:00

  • Intact microtubules are necessary for complete processing, storage and regulated secretion of von Willebrand factor by endothelial cells.

    abstract::The importance of intact microtubules in the processing, storage and regulated secretion of von Willebrand factor (vWf) from Weibel-Palade bodies in endothelial cells was investigated. Human umbilical vein endothelial cells treated for 1 h with colchicine (10(-6) M) or nocodozole (10(-6) M) lost their organized microt...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:

    authors: Sinha S,Wagner DD

    更新日期:1987-06-01 00:00:00

  • Molecular dissection of ODF2/Cenexin revealed a short stretch of amino acids necessary for targeting to the centrosome and the primary cilium.

    abstract::The outer dense fiber protein ODF2 is the major component of the sperm tail cytoskeleton and a critical component of the mature centriole of the centrosome. Centriole maturation involves the formation of appendages and the recruitment of ODF2/Cenexin. ODF2 and Cenexin are alternative splice variants that differ in a s...

    journal_title:European journal of cell biology

    pub_type: 杂志文章

    doi:10.1016/j.ejcb.2007.10.004

    authors: Hüber D,Geisler S,Monecke S,Hoyer-Fender S

    更新日期:2008-03-01 00:00:00