Photochemical intermediate of third rhodopsin-like pigment in Halobacterium halobium by simultaneous illumination with red and blue light.

abstract：:ATP-binding cassette sub-family G member 2 (ABCG2) confers to the major phenotypes of side population (SP) cells, the cancer stem-like cells. In this study, the SP cells displayed a distinctly higher ABCG2 expression level, sphere formation efficiency (SFE) and growth rate even under hypoxia condition. CXCR4 overexpre...

journal_title：Biochemical and biophysical research communications

authors： He C,Zhang H,Wang B,He J,Ge G

更新日期：2018-10-28 00:00:00

abstract：:KRAS is the key mutated gene in pancreatic ductal adenocarcinoma (PDAC). Emerging evidence indicates that KRas modulates endocytic uptake. The present study aimed to explore the fate of early endosomal trafficking under the control of KRas expression in PDAC. Surprisingly, PANC-1 cells lacking KRas exhibited significa...

journal_title：Biochemical and biophysical research communications

authors： Teske C,Schweitzer C,Palamidessi A,Aust DE,Scita G,Weitz J,Welsch T

更新日期：2017-11-04 00:00:00

abstract：:The immunological recognition pattern of one of the most commonly used monoclonal antibodies, PHF-1, which detects the paired helical filaments of Alzheimer's disease, exhibits a high degree of similarity with the recognition of a polyclonal antibody, anti-T3P, raised against a synthetic phosphopeptide, GAEIVYKS(Phosp...

journal_title：Biochemical and biophysical research communications

authors： Lang E,Szendrei GI,Lee VM,Otvos L Jr

更新日期：1992-09-16 00:00:00

abstract：:The whole-cell patch-clamp technique has been applied to elucidate the effects of H2O2 and the SH-group reagent 2,2'-dithio-bis(5-nitropyridine) (DTBNP) on Ca2+ currents of mouse pancreatic B-cells. We also tested the effect of DTBNP on the whole-cell K+ ATP current. DTBNP (20 and 100 mumol/l) blocked both the current...

journal_title：Biochemical and biophysical research communications

authors： Krippeit-Drews P,Britsch S,Lang F,Drews G

更新日期：1994-04-29 00:00:00

abstract：:alpha-Crystallin, a major eye lens protein, has been shown to function like a molecular chaperone by suppressing the aggregation of other proteins induced by various stress conditions. Ultraviolet (UV) radiation is known to cause structural and functional alterations in the lens macromolecules. Earlier we observed tha...

journal_title：Biochemical and biophysical research communications

authors： Reddy GB,Reddy PY,Suryanarayana P

更新日期：2001-04-06 00:00:00

abstract：:The aim of this work was to study the time course of the oxidative metabolism in mice lung after exposure to ambient particles (ROFA). Swiss mice were intranasally instilled with a ROFA suspension (0.20 mg/kg). Animals were sacrificed 1 or 3 h after the exposure. Eighty percentage of increased oxygen consumption was o...

journal_title：Biochemical and biophysical research communications

authors： Magnani ND,Marchini T,Tasat DR,Alvarez S,Evelson PA

更新日期：2011-09-09 00:00:00

abstract：:Lung metastasis is a primary obstacle in the clinical treatment of metastatic breast cancer. Most patients with lung metastasis eventually die of recurrence. Recurrence may be related to self-seeding, which occurs when circulating tumor cells re-seed into the tumors they originated from (metastasis or carcinoma in sit...

journal_title：Biochemical and biophysical research communications

authors： Huang H,Zheng X,Cai C,Yao Z,Lu S,Meng X,Miao Y,He Z,Cai C,Zou F

更新日期：2018-09-03 00:00:00

abstract：:The signal transduction of human 12(S)-lipoxygenase and the regulation of gene activation, induced by epidermal growth factor (EGF), are discussed in this review article. Treatment of human epidermoid carcinoma A431 cells with EGF induces the gene expression of human 12(S)-lipoxygenase, and two Sp1 binding sites resid...

journal_title：Biochemical and biophysical research communications

authors： Chang WC,Chen BK

更新日期：2005-12-09 00:00:00

abstract：:Betulinic acid (BA) exhibits various biological activities such as anti-bacterial, anti-inflammatory, anti-human papilloma virus (HPV), and anti-cancer activities. HPV infection is associated with a high risk of cervical cancer, which is the leading cause of deaths among women worldwide. Therefore, BA is an attractive...

journal_title：Biochemical and biophysical research communications

authors： Kim HJ,Cho HS,Ban HS,Nakamura H

更新日期：2020-03-12 00:00:00

abstract：:Class-I phosphoinositide 3-kinases (PI 3-kinases) are dual specificity enzymes that possess both lipid and protein kinase activity. While the best characterized property of this protein kinase is as an autokinase activity, there have also been reports it can phosphorylate exogenous substrates including peptides, IRS-1...

journal_title：Biochemical and biophysical research communications

authors： Foukas LC,Shepherd PR

更新日期：2004-06-25 00:00:00

abstract：:The myelin basic proteins (MBPs) are a family of polypeptides that are predominantly expressed in the nervous system where they play a major role in myelination. We have generated four lines of transgenic mice carrying a transgene in which 1.34 kb of the 5'-flanking sequence of the mouse MBP gene was fused upstream of...

journal_title：Biochemical and biophysical research communications

authors： Asipu A,Mellor AL,Blair GE

更新日期：2001-11-09 00:00:00

abstract：:The mitochondrial respiratory chain (MRC) supplies the majority of the energy requirements of most eucaryotic cells. A null mutation in the Caenorhabditis elegans nuo-1 gene encoding a subunit of complex I (NADH-ubiquinone oxidoreductase) is lethal, leading to a developmental arrest at the third larval stage. To ident...

journal_title：Biochemical and biophysical research communications

authors： Ndegwa S,Lemire BD

更新日期：2004-07-09 00:00:00

abstract：:Although the introduction of cyclosporine A (CyA) and FK506 for immunosuppressive therapy has dramatically enhanced the early survival of organ transplant recipients, administration of these immunosuppresants is correlated with high incidence of transplant arteriosclerosis. Transplant-associated arteriosclerosis is be...

journal_title：Biochemical and biophysical research communications

authors： Sata M,Walsh K

更新日期：1999-09-24 00:00:00

abstract：:Force impulse is thought to be generated in muscle when myosin head (S-1), while weakly bound to actin filament, undergoes orientational change to form a strong (rigor) bond with actin. There is ample evidence that this bond involves interaction of 1 myosin head with 1 actin monomer. However, X-ray diffraction data of...

journal_title：Biochemical and biophysical research communications

authors： Andreev OA,Borejdo J

更新日期：1991-05-31 00:00:00

abstract：:Abnormal proliferation of vascular smooth muscle cells is a key event in the formation of atherosclerotic plaques in humans. It has been suggested that modulation of platelet derived growth factor chain A (PDGF-A) gene expression may contribute to atherosclerosis. Using an 'in situ hybridization' technique the present...

journal_title：Biochemical and biophysical research communications

authors： Zwijsen RM,Japenga SC,Heijen AM,van den Bos RC,Koeman JH

更新日期：1992-08-14 00:00:00

abstract：:Dual effect of dibromothymoquinone ( DBMIB ), inhibitor and reducing agent at the donor side of Photosystem I, was investigated in isolated intact chloroplasts by flash-induced absorbance changes at 820 and 515 nm. We show that in the absence of other electron donors, rereduction of P700+ by DBMIB proceeds at a very l...

journal_title：Biochemical and biophysical research communications

authors： Farineau J,Bottin H,Garab G

更新日期：1984-05-16 00:00:00

abstract：:Using fluorescein isothiocyanate (FITC)-conjugated H-2K(b) CTL epitope (SIINFEKL) as a model system, we investigated the antigen delivery route by pH-sensitive liposomes in vivo. Fluorescence was initially detected in lymph nodes at 3 h after immunization, and its intensity reached a peak value in superticial inguinal...

journal_title：Biochemical and biophysical research communications

authors： Lee KY,Chun E,Seong BL

更新日期：2002-04-05 00:00:00

abstract：:A rabbit liver P-450-like pseudogene has been isolated from a lambda phage genomic library. Sequence analysis revealed structural homology with respect to the rat P-450b and P-450e genes as well as a similar intron-exon organization. A 5'-proximal TATA box-like sequence and two 3'-distal putative polyadenylation signa...

journal_title：Biochemical and biophysical research communications

authors： Zaphiropoulos PG,Folk WR,Coon MJ

更新日期：1986-01-29 00:00:00

abstract：:Xylan from Rhodymenia palmata binds to the cellobiohydrolase I from Trichoderma reesei (CBH I) or its core protein, inhibiting their activity. Adsorption onto microcrystalline cellulose (Avicel) is reduced approximately 30% for intact CBH I and nearly 50% for the core, whereas the effects with cellobiose are negligibl...

journal_title：Biochemical and biophysical research communications

authors： Abuja PM,Pilz I,Tomme P,Claeyssens M

更新日期：1989-12-15 00:00:00

abstract：:Cytotoxic CD8(+) T cells are particularly important to the development of protective immunity against the intracellular protozoan parasite, Trypanosoma cruzi, the etiological agent of Chagas disease. We have developed a new effective strategy of genetic immunization by activating CD8(+) T cells through the ubiquitin-f...

journal_title：Biochemical and biophysical research communications

authors： Chou B,Hiromatsu K,Hisaeda H,Duan X,Imai T,Murata S,Tanaka K,Himeno K

更新日期：2010-02-12 00:00:00

abstract：:Neuregulins comprise a group of growth factor proteins that regulate the differentiation of skeletal muscle. Here, we report that neuregulins are regulators of myogenic differentiation and stimulate mitogenesis in L6 skeletal myoblasts. The mitogenic response to neuregulin-1 was differentiation-dependent and observed ...

journal_title：Biochemical and biophysical research communications

authors： Ford BD,Han B,Fischbach GD

更新日期：2003-06-20 00:00:00

abstract：:Cot/Tpl2, a member of MAP kinase kinase kinase (MAPKKK), is indispensable for the ERK activation, as well as the production of TNF-α, IL-1β, IL-23, and PGE(2) in lipopolysaccharide (LPS)-stimulated macrophages. However, the expression and the functional roles of Cot/Tpl2 in mast cells have not been elucidated. The adm...

journal_title：Biochemical and biophysical research communications

authors： Chiba N,Kakimoto K,Masuda A,Matsuguchi T

更新日期：2010-11-05 00:00:00

abstract：:CD40-mediated signals can induce cell aggregation, proliferation and rescue from apoptosis in WEHI231. To define which segment of cytoplasmic domain of CD40 and how signals are involved in those events, we generated mutant CD40 transfectants. We demonstrated the same 10 amino acid segment that could bind to tumor necr...

journal_title：Biochemical and biophysical research communications

authors： Hara T,Murakami M,Maeda H,Hibi M,Uede T

更新日期：1997-04-07 00:00:00

abstract：:Lysosomal integral membrane protein-2 (LIMP-2) is a type III transmembrane protein that is highly glycosylated and mainly localized to the lysosomal membrane. The diverse functions of LIMP-2 are currently being uncovered; however, its participation in macroautophagy, usually described as autophagy, has not yet been we...

journal_title：Biochemical and biophysical research communications

authors： Sakane H,Urabe J,Nakahira S,Hino K,Miyata N,Akasaki K

更新日期：2020-12-17 00:00:00

abstract：:Myosin heavy chain (MHC) mRNA isoforms were quantified in soleus (SOL) and gastrocnemius (GAS) muscles from rats exposed to 14 days of either hindlimb unweighting (HU), clenbuterol treatment (CB), or HU combined with CB treatment (HU-CB). All conditions induced in SOL a shift from slow to faster MHC mRNA isoforms and ...

journal_title：Biochemical and biophysical research communications

authors： Stevens L,Gohlsch B,Mounier Y,Pette D

更新日期：2000-08-28 00:00:00

abstract：:Endothelin-1 (ET-1) is a 21-amino acid vasoactive peptide produced from a 39-amino acid biologically inactive peptide, big ET-1, by the action of endothelin-converting enzyme-1 (ECE-1). We investigated gastric mucosal expression of ECE-1 during a 16 h course of inflammatory responses associated with gastric mucosal in...

journal_title：Biochemical and biophysical research communications

authors： Slomiany BL,Slomiany A

更新日期：2000-03-16 00:00:00

abstract：:Several chemokines, belonging to both the CXC and CC classes, act as positive or negative regulators of angiogenesis. We sought to investigate the role of CXCL13, B cell-attracting chemokine 1 (BCA-1), also known as B-lymphocyte chemoattractant (BLC), on endothelial cell functions. We tested the effect of CXCL13 on HU...

journal_title：Biochemical and biophysical research communications

authors： Spinetti G,Camarda G,Bernardini G,Romano Di Peppe S,Capogrossi MC,Napolitano M

更新日期：2001-11-23 00:00:00

abstract：:Catabolite inactivation of fructose 1,6-bisphosphatase and cytoplasmic malate dehydrogenase was studied using the protease-deficient and vacuole-defective yeast strain pep4-3. The catabolite inactivation of fructose 1,6-bisphosphatase in pep4-3 was found to have a normal first inactivation step but with a defective se...

journal_title：Biochemical and biophysical research communications

authors： Funaguma T,Toyoda Y,Sy J

更新日期：1985-07-16 00:00:00

abstract：:Hepatitis C virus (HCV) infects its target cells in the form of cell-free viruses and through cell-cell contact. Here we report that HCV is associated with exosomes. Using highly purified exosomes and transmission electron microscopic imaging, we demonstrated that HCV occurred in both exosome-free and exosome-associat...

journal_title：Biochemical and biophysical research communications

authors： Liu Z,Zhang X,Yu Q,He JJ

更新日期：2014-12-12 00:00:00

abstract：:This study characterized the magnetic materials found within Daphnia resting eggs by measuring static magnetization with a superconducting quantum interference device (SQUID) magnetometer, after forming two types of conditions, each of which consists of zero-field cooling (ZFC) and field cooling (FC). Magnetic ions, s...

journal_title：Biochemical and biophysical research communications

authors： Sakata M,Kawasaki T,Shibue T,Takada A,Yoshimura H,Namiki H

更新日期：2006-12-15 00:00:00