Abstract:
:Biomphalaria glabrata can react through different pathways to Schistosoma mansoni miracidium penetration, according to the degree of resistance/susceptibility presented by different snail strains, which is a genetically determined character, resistance being the dominant feature. However, it has been observed that previous susceptible snail strain may change its reactive behavior along the course of infection, exhibiting later a pattern of cercarial shedding and histopatopathological picture compatible with high resistance. Such observation suggests the possibility of B. glabrata to develop a sort of adaptative immunity face a schistosome infection. To explore on this aspect, the present investigation looked for the behavior of S. mansoni infection in B. glabrata previously subjected to different means of artificial stimulation of its internal defense system. Snails previously inoculated with irradiated miracídia (Group I); treated with S. mansoni antigens (Group II) or with a non-related parasite antigen (Group III) were challenged with 20 viable S. mansoni miracidia, and later looked for cercarial shedding and histopathologic changes at different times from exposition. Nodules of hemocyte accumulations were found at the site of antigen injection. These nodules resembled solid granulomas, and were larger and more frequent in snails injected with S. mansoni products as compared to those injected with Capillaria hepatica. However, the presence of such granulomas did not avoid the S. mansoni challenge infection from developing in a similar way as that seen in controls. The data are indicative that hemocytes are able to proliferate locally when stimulated, such capacity also remaining localized, not being shared by the population of hemocytes located elsewhere within the snail body.
journal_name
Mem Inst Oswaldo Cruzjournal_title
Memorias do Instituto Oswaldo Cruzauthors
Azevedo CM,Borges CC,Andrade ZAdoi
10.1590/s0074-02762006000900031subject
Has Abstractpub_date
2006-09-01 00:00:00pages
199-203eissn
0074-0276issn
1678-8060pii
S0074-02762006000900031journal_volume
101 Suppl 1pub_type
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02761990000300013
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journal_title:Memorias do Instituto Oswaldo Cruz
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doi:10.1590/s0074-02762010000200004
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journal_title:Memorias do Instituto Oswaldo Cruz
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journal_title:Memorias do Instituto Oswaldo Cruz
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journal_title:Memorias do Instituto Oswaldo Cruz
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更新日期:2007-06-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
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doi:10.1590/0074-02760180279
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journal_title:Memorias do Instituto Oswaldo Cruz
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abstract::A semiarid area of northwest Costa Rica where Lutzomyia longipalpis is common in corrals around houses is described. Monthly captures of the sandfly during two consecutive years for fixed periods of time indicated that the insect bites avidly cows, horses, pigs, dogs and humans. From a total of 14,215 specimens, 90.5%...
journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02761984000400010
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journal_title:Memorias do Instituto Oswaldo Cruz
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02762008000200009
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02762004000300017
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Lutzomyia umbratilis, the vector for Leishmania guyanensis in northern South America, has been found naturally infected with L. guyanensis only in areas north of the Negro and Amazon rivers. While populations of this sand fly species are also found in areas south of these rivers, these populations have never...
journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章,评审
doi:10.1590/s0074-02762003000700001
更新日期:2003-10-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
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更新日期:1997-07-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
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doi:10.1590/s0074-02761991000600044
更新日期:1991-01-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02762010000300006
更新日期:2010-05-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02762005000500012
更新日期:2005-08-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章,meta分析,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
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journal_title:Memorias do Instituto Oswaldo Cruz
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
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更新日期:2003-01-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/0074-0276140024
更新日期:2014-07-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
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更新日期:2011-11-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02762008000600013
更新日期:2008-09-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/0074-0276130550
更新日期:2014-09-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
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更新日期:2016-05-24 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/0074-02760160334
更新日期:2017-03-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02762001000400018
更新日期:2001-05-01 00:00:00
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journal_title:Memorias do Instituto Oswaldo Cruz
pub_type: 杂志文章
doi:10.1590/s0074-02761998000700014
更新日期:1998-01-01 00:00:00