Abstract:
BACKGROUND:In the year 2000, the photodynamic therapy (PDT) was introduced as a new option for the treatment of exudative choroidal neovascularisation (CNV). Since this kind of therapy required the health insurance company's consent, the waiting period for the first therapy varied considerably. MATERIALS AND METHODS:Between July 2000 and September 2004, 133 eyes were treated via PDT. In this study, 59 courses were analysed retrospectively, all of them within the frame of a classic or predominantly classic exudative CNV. RESULTS:At the time of indication for the therapy, 38.46 % of the eyes of patients under the age of 65 and 73.91 % of the eyes of patients over the age of 65 showed a visual acuity (VA) of less than 0.3. Nine eyes lost the VA needed to drive a car (> or = 0.6), eight eyes lost the reading ability (< 0.4) before the first PDT. One eye lost its reading ability, one eye reached the classification of "visually handicapped & blindness" (< or = 0.3) and one eye went blind (< or = 0.02) within 7 days of waiting time. CONCLUSION:Elderly people showed less VA at first investigations by ophthalmologists, which underscores the necessity of an intensive campaign about the classic symptoms of AMD. The results of this study confirm that loss of VA can be caused by CNV progression within seven days. Whether or not rapid treatment with PDT influences the visual and morphological outcome, has to be proven by more extensive studies.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Böhm MR,Busse H,Uhlig CEdoi
10.1055/s-2007-962955subject
Has Abstractpub_date
2007-02-01 00:00:00pages
129-34issue
2eissn
0023-2165issn
1439-3999journal_volume
224pub_type
杂志文章abstract::As a result of an acute pathologic event ophthalmic arterial pressure may fall below a level necessary to supply sufficient blood to the eye and optic nerve, and thus to preserve full visual function. A sudden partial or even total loss of visual function. A sudden partial or even total loss of vision may follow. In s...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057432
更新日期:1980-02-01 00:00:00
abstract::On the basis of SEM studies it has been shown that the cilia are arranged into groups of 10 to 40 in the individual epithelial cells of the lacrimal sac. The cilia have a length of 15 to 20 micron. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-03-01 00:00:00
abstract::Report on a rare case of an iris-ringmelanoma. Arising from the iris base the primary tumor spread in a continuous line along the anterior chamber angle and a shedding of tumor cells in other places of the iris surface could be stated as well. A unilateral dark spotted colouring of the iris with a secondary glaucoma w...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract::This paper presents results of measurements of laser adhesions in rabbit eyes. A circular area of the retina 2.5 mm in diameter was covered with laser burns (diameter of laser beam 200 microns). The strength of the adhesion was measured on the 8th and 22nd days after coagulation. The adhesive area consisted of 60-65 l...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1054567
更新日期:1984-07-01 00:00:00
abstract::Spectacles worn by vehicle drivers should fulfil the demands set down by DIN 58 216 standards and should furthermore be constructed in such a manner that the binocular field of vision is impaired as little as possible. In this connection, the nasal parts of the frame are particularly important. The external and intern...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-07-01 00:00:00
abstract::Diagnosis and treatment of disturbances of binocular vision are made possible by a new orthoptic training device, which is a combination of Bagolini glasses, double prisms and a fixation target which can be shifted sagitally. It combines fusion, accommodation and convergence. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057445
更新日期:1980-02-01 00:00:00
abstract:BACKGROUND:We describe a case of central serous chorioretinopathy associated with a large adrenal myelolipoma. HISTORY AND SIGNS:A 55-year old man was admitted to our clinic complaining for metamorphopsia and blurred vision in his left eye. Standard ophthalmologic examination and fluorescein angiography established th...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2003-38187
更新日期:2003-03-01 00:00:00
abstract::Basing on the bipolar-coaxial wetfield-diathermy, introduced in microsurgery 1974 by the author, an anterior capsulotomy instrument using a modulated RF-current was published in 1984. In the meantime several patients have been operated successfully with this technique. However, further experimental studies allowed a r...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045809
更新日期:1992-05-01 00:00:00
abstract::In a study lasting 16 months, Timolol was tested on 57 eyes of a group of selected patients with open-angle glaucoma. Patients whose IOP could not be stabilized with the 0.25% solution were treated with 0.5% drops twice a day. In five separate cases, where regulation was inadequate, pilocarpine 2% twice a day was pres...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:
更新日期:1979-11-01 00:00:00
abstract::Intact or denuded bovine corneas were incubated in the presence of 14lC GlcN and parts of the proteoglycan-glycoprotein complexes of the stroma were extracted by 0.15M NaCl and successively by 1.0M CaCl2. The specific activities of total GAG and KS were determined. In the presence of the epithelial layer the biosynthe...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-12-01 00:00:00
abstract::Anti-VEGF injections are widely used "off-label" for the treatment of choroidal neovascularization secondary to pathological myopia based on data generated by multiple case series with small sample sizes. In this review we have analyzed the results of case series with at least 20 patients and a follow-up of ≥ 12 month...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,meta分析,评审
doi:10.1055/s-0034-1368289
更新日期:2014-04-01 00:00:00
abstract::Report on a 69-year-old woman with a choroidal and a large peribulbar tumor. A scan ultrasonography of the peribulbar mass revealed a homogeneous structure of the lymphoma/sarcoma/pseudo-tumor type. Histological examination disclosed a reactive lymphoid hyperplasia without "Dutcher bodies", and consistent with a benig...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057457
更新日期:1980-02-01 00:00:00
abstract::Julius Hirschberg of Berlin was one of the most brilliant ophthalmologists of his time. As a surgeon and as the editor of the "Centralblatt für praktische Augenheilkunde" (1877-1919) he enjoyed a world-wide reputation. He devised an electrical hand magnet for the extraction of intraocular foreign bodies (1879 - see Du...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Kaposi's sarcoma occurs as a complication in numerous cases of AIDS, the much-discussed acquired immune deficiency syndrome. Considering the latter's near-epidemic incidence, the clinical and histological features of Kaposi's sarcoma are recalled to mind. Hitherto only sporadically recorded in non-African countries, t...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050977
更新日期:1985-07-01 00:00:00
abstract:BACKGROUND:The mean diclofenac level in the aqueous humor after i.v.-injection should be examined as an example for other systemic applied drugs. The clinical effect is to be evaluated with regard to perioperative anti-inflammatory therapy in patients undergoing cataract surgery. PATIENTS AND METHODS:In this prospecti...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2001-12250
更新日期:2001-02-01 00:00:00
abstract::A 46 year old AIDS-patient, who had developed CMV-retinitis was treated with the virostatic drug dihydroxypropoxymethylguanine (DHPG, Ganciclovir) over a period of 16 months until he died due to a pneumonia. After the DHPG-treatment was initiated the retinitis improved markedly, however there still was a very slow pro...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046305
更新日期:1990-11-01 00:00:00
abstract::The suitability of ultrasonography, computer tomography and Octopus perimetry is illustrated with reference to an investigation carried out in 60 patients. First, the characteristic symptoms are described, depending on the localization of the lesion in the visual pathway. Then the advantages and disadvantages of the v...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1055172
更新日期:1982-08-01 00:00:00
abstract::A horizontal diplopia is produced with prisms whose bases are nasal or temporal. The subject has to fixate a circle, now seen double, alternately with his left and right eye and touch the center of the circle with a finger. Of one hundred subjects thus examined, 85 located the circle accurately every time when the one...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046410
更新日期:1989-07-01 00:00:00
abstract::There are three forms of lens dislocation in the posterior segment: intravitreal, prebasal, and intrabasal. The location of the dislocated lens depends on gravity and the condition of the vitreous body. As a rule the dislocated lens lies at the bottom of the vitreous cavity; it may be completely embedded in the vitreo...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050310
更新日期:1988-12-01 00:00:00
abstract:PURPOSE:Endothelial cell damage can be found after a phacoemulsification. The reason for this cell damage is not yet known. The temperature rise inside the anterior chamber during the emulsification of the lens is considered as a potential damage mechanism. The aim of this study was to investigate the relationship betw...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0034-1382848
更新日期:2014-08-01 00:00:00
abstract::The response by 14 patients with open-angle glaucoma to treatment with carteolol 1% eye drops was investigated during a study lasting up to 15 months. Statistical analysis of the data revealed that carteolol had a highly significant IOP-lowering effect in all the patients studied. The mean decrease in IOP was as much ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2008-1050860
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:Little is known about how the expression of Ephrin type-A receptor 2 (EphA2) influences cell-cell adhesion, migration, angiogenesis, and the formation of vasculogenic mimicry (VM) channels in uveal melanomas or how this may be related to the rate of metastasis. MATERIAL AND METHODS:Paraffin embedded section...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0041-110956
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Additive manufacturing and 3D printing create new paths for the design and manufacturing of implants. Technologies with high resolution are required for the development of microstructured eye implants. In the present study, we demonstrate how these technologies can be used during the design development and m...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0041-107883
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to assess the efficacy of radiotherapy as first line therapy for the treatment of primary localised orbital lymphomas of low malignancy (St IE) based on our cases. METHODS:7 patients with histologically proven primary localised orbital lymphomas of low malignancy treated with radiothe...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-0029-1245330
更新日期:2010-07-01 00:00:00
abstract::The present paper reports on the clinical findings of a 34-year-old male patient with MELAS syndrome. MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis and strokelike episodes) belongs to a group of syndromes called mitochondrial encephalomyopathies that are characterized by changes of the mitochondrial...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046280
更新日期:1990-09-01 00:00:00
abstract::Ocular radiotherapy has considerably improved during the last 60 years. It allows very often, not only to save an eye, but also to maintain a useful function. But it is only one single element, although important, in our fight against intraocular tumors. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-06-01 00:00:00
abstract:BACKGROUND:To investigate the structural basis for functional deficits in infantile strabismus we used a neuroanatomic tracer and a histochemical label to examine the primary visual cortex (area V1) of adult esotropic macaque monkeys. ANIMALS AND METHODS:The animals had developed natural esotropia in the first months ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035162
更新日期:1996-01-01 00:00:00
abstract::The crucial aetiological factors of idiopathic retinal detachment are posterior vitreous detachment with collapse, and degenerative lesions in the fundus periphery. Posterior vitreous detachment does not imply diagnostic problems to the expert in this field. On the other hand, the peripheral retinal degenerations incl...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057296
更新日期:1981-10-01 00:00:00
abstract::Biological, rather then purely technical approach seems to be very essential to ensure better results in alloplasty of the cornea. The diseased corneal tissue (especially, after corneal burns) usually fails to accept a keratoprosthesis permanently. The cornea must, therefore, be biologically reconstructed by transplan...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-05-01 00:00:00
abstract::Between january 1986 and december 1989 we prospectively studied 211 patients with branch retinal vein occlusion (BRVO). Documented by fundus photography and fluorescein angiography clinical and angiographic findings were analysed. The age ranged from 28 to 83 with a mean of 63 years. 104 (48.8%) patients were male, 10...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045901
更新日期:1992-10-01 00:00:00