Low acid output in Pima Indians. A possible cause for the rarity of duodenal ulcer in this population.

abstract：:To evaluate the influence of chronic alcoholism on clinical features of chronic pancreatitis in Japan, pain evolution, pancreatic insufficiency, and long-term prognosis were studied by comparing chronic alcoholic pancreatitis (N = 88) with idiopathic pancreatitis (N = 67). The 155 patients with known course of the dis...

journal_title：Digestive diseases and sciences

authors： Hayakawa T,Kondo T,Shibata T,Sugimoto Y,Kitagawa M

更新日期：1989-01-01 00:00:00

abstract：:Campylobacter pyloridis has been associated with antral gastritis and duodenal ulcer. To study the pathogenetic role of these organisms in duodenal ulcer, endoscopic biopsies, two from the first part of duodenum, four from antrum, and four from body and fundus, were taken before and after four weeks of cimetidine trea...

journal_title：Digestive diseases and sciences

authors： Hui WM,Lam SK,Chau PY,Ho J,Lui I,Lai CL,Lok AS,Ng MM

更新日期：1987-11-01 00:00:00

abstract：:The literature regarding the effect of nicotine and cigarette smoke on gastric blood flow is conflicting. The hydrogen gas clearance technique was used to measure the effects of nicotine and cigarette smoke on basal gastric mucosal blood flow in anesthetized rats. Blood flow was measured before, during, and after trea...

journal_title：Digestive diseases and sciences

authors： Robert ME,Leung FW,Guth PH

更新日期：1986-05-01 00:00:00

abstract：:Forty-one (98%) of 42 patients with achalasia of the esophagus had pneumatic dilatation performed successfully using the Brown-McHardy dilator. One to four dilatations (mean, 1.9) were done on each patient with inflation pressures of 8-15 psi (mean, 11.1 psi). Immediately after the procedure, all patients were examine...

journal_title：Digestive diseases and sciences

authors： Ott DJ,Richter JE,Wu WC,Chen YM,Castell DO,Gelfand DW

更新日期：1987-09-01 00:00:00

abstract：:Inhibition of monoamine oxidase B (MAO B) by selective inhibitors pargyline and L-deprenyl increases dopamine (DA) and norepinephrine (NE) concentrations in nucleus accumbens (NACB) and is associated with reduction in cold water restraint-induced gastric mucosal injury, inhibition of basal gastric acid output, and reg...

journal_title：Digestive diseases and sciences

authors： Xing LP,Washington J,Seaton J,Kauffman G Jr

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Acute variceal bleeding (AVB) in patients with cirrhosis is associated with high mortality, ranging from 12 to 20% at 6 weeks. The existing prognostic models for AVB lack precision and require further validation. AIM:In this prospective study, we aimed to develop and validate a new prognostic model for AVB,...

journal_title：Digestive diseases and sciences

authors： Rout G,Sharma S,Gunjan D,Kedia S,Saraya A,Nayak B,Singh V,Kumar R,Shalimar

更新日期：2019-08-01 00:00:00

abstract：:A retrospective multicenter analysis of 652 patients with chronic hepatitis C who have been treated with interferon (IFN) was performed to assess the effects of IFN on the clinical course and development of HCC. During a mean follow-up of 54.8 months, hepatocellular carcinoma (HCC) developed in 7.0% of the patients. T...

journal_title：Digestive diseases and sciences

authors： Takimoto M,Ohkoshi S,Ichida T,Takeda Y,Nomoto M,Asakura H,Naito A,Mori S,Hata K,Igarashi K,Hara H,Ohta H,Soga K,Watanabe T,Kamimura T

更新日期：2002-01-01 00:00:00

abstract：:Azithromycin (Zithromax), an erythromycin derivative that belongs to a subgroup of the macrolides known as azolides, has generally been considered to be a very safe medication. Hepatic side effects are uncommon but may include jaundice, fever, and right upper quadrant pain. Herein we describe a patient who developed a...

journal_title：Digestive diseases and sciences

authors： Chandrupatla S,Demetris AJ,Rabinovitz M

更新日期：2002-10-01 00:00:00

abstract：:Data about colonic mucosa transport of short-chain fatty acids in cirrhotic patients are still lacking. The aim of the present study was to compare the rectal mucosa transport of n-butyrate and its effect on transport of other electrolytes and endoluminal pH in normal subjects and in cirrhotic patients by using a rect...

journal_title：Digestive diseases and sciences

authors： Onori L,Pimpo MT,Palumbo GC,Gili L,Marchetti G,Saltarelli P,Aggio A,Frieri G

更新日期：2001-10-01 00:00:00

abstract：:Because of the technical difficulty during subsequent surgical intervention, adhesion remains the most important predictor of outcome in the staged procedures following emergent colorectal surgery. The aim of this study was to assess the long-term effects of hyaluronan (HA)-based adhesion barriers 3 months following t...

journal_title：Digestive diseases and sciences

authors： Tüzüner A,Kuzu MA,Akin B,Karaca S,Hazinedaroglu S

更新日期：2004-06-01 00:00:00

abstract：:Impairment of pancreatic microcirculation has often been advocated as one pathogenic mechanism in necrotizing pancreatitis. In contrast, data on pancreatic capillary perfusion in edematous pancreatitis are scarce. It was the aim of this experimental study to compare changes in pancreatic microcirculation in edematous ...

journal_title：Digestive diseases and sciences

authors： Klar E,Schratt W,Foitzik T,Buhr H,Herfarth C,Messmer K

更新日期：1994-12-01 00:00:00

abstract：:A comparative study of three different high-dose regimens of interferon-alpha-2b (IFN) was conducted in patients with chronic hepatitis C to determine which was better at obtaining a sustained remission. A total of 126 patients were assigned randomly to one of three groups: group A was given 10 million international u...

journal_title：Digestive diseases and sciences

authors： Iino S,Hino K,Kuroki T,Suzuki H,Yamamoto S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Nonalcoholic fatty liver disease (NAFLD) is the number one cause of liver disease in the United States. The prevalence rates in African Americans (AA), while significantly lower than other ethnic groups with similar known risk factors, have been quoted as high as 24 %. We aim to determine if the pre...

journal_title：Digestive diseases and sciences

authors： Foster T,Anania FA,Li D,Katz R,Budoff M

更新日期：2013-08-01 00:00:00

abstract：:Lafutidine, a histamine H2-receptor antagonist, exhibits gastric mucosal protective action mediated by capsaicin-sensitive afferent neurons, in addition to a potent antisecretory effect. In this study we examined the effect of lafutidine on dextran sulfate Na (DSS)-induced ulcerative colitis in rats, in relation to ca...

journal_title：Digestive diseases and sciences

authors： Okayama M,Tsubouchi R,Kato S,Takeuchi K

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:In previous studies the NFKBIA 3'UTR (untranslated region) AA genotype was associated with Crohn's disease (CD), while the NFKB1-94ins/delATTG mutation increased the risk for ulcerative colitis (UC). The aim of our study was to investigate these two polymorphisms and patients' response to medical therapy and/or...

journal_title：Digestive diseases and sciences

authors： Szamosi T,Lakatos PL,Hungarian IBD Study Group.,Szilvasi A,Lakatos L,Kovacs A,Molnar T,Altorjay I,Papp M,Szabo O,Satori A,Tulassay Z,Miheller P,Horvath HC,Papp J,Tordai A,Andrikovics H

更新日期：2009-02-01 00:00:00

abstract：AIM:The aim of this study was to assess whether patients with colorectal cancer (CRC) are aware of the risk to family members and to test an educational intervention. METHODS:CRC patients were surveyed regarding their cancer, family history, understanding of familial risk of CRC, and knowledge of existing screening gu...

journal_title：Digestive diseases and sciences

authors： Rubin DT,Gandhi RK,Hetzel JT,Kinnear SH,Aronsohn A,Wood G,Yadron N

更新日期：2009-11-01 00:00:00

abstract：:The neutralizing capacity of two antacids (Alucol = A, Syntrogel = S), differing both in their composition and theoretical neutralizing capacity, was evaluated in vitro and in vivo. In vitro at pH 3.5, 1 ml of A or S neutralizes 3.9 and 1.6 meq of acid, respectively, in an aqueous solution. When tested in vivo in the ...

journal_title：Digestive diseases and sciences

authors： Berchtold P,Reinhart WH,Niederhäuser U,Koller U,Halter F

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:The colon is partly controlled by myenteric and submucosal plexuses, which respond to stress and lead to some gastrointestinal disorders. These plexuses play roles in irritable bowel syndrome. Patients suffering from this syndrome can be treated with some antidepressants, including sertraline and nortriptyli...

journal_title：Digestive diseases and sciences

authors： Noorafshan A,Yousefi M,Hosseini L,Karbalay-Doust S

更新日期：2019-09-01 00:00:00

abstract：:Some patients referred for esophagogastroduodenoscopy (EGD) to evaluate symptoms of dysphagia have normal endoscopies. How best to manage these patients is unclear. We reviewed our experience with empiric esophageal dilation in this setting. Over a five-year period, 40 consecutive patients with esophageal dysphagia an...

journal_title：Digestive diseases and sciences

authors： Marshall JB,Chowdhury TA

更新日期：1996-06-01 00:00:00

abstract：:Although the pathogenic mechanisms of inflammatory bowel diseases are not fully understood, colonic microbiota may affect the induction of colonic inflammation, and some probiotics and prebiotics have been reported to suppress colitis. The inhibitory effects of brown rice fermented by Aspergillus oryzae (FBRA), a fibe...

journal_title：Digestive diseases and sciences

authors： Kataoka K,Ogasa S,Kuwahara T,Bando Y,Hagiwara M,Arimochi H,Nakanishi S,Iwasaki T,Ohnishi Y

更新日期：2008-06-01 00:00:00

abstract：:The effects of chronic normovolemic anemia on gastric microcirculation and gastric mucosal susceptibility to ethanol-induced gastric damage were investigated in anesthetized rats. Blood exchange by a plasma expander during four consecutive days rendered the animals anemic with a 34% decrease in the baseline hematocrit...

journal_title：Digestive diseases and sciences

authors： Marroni N,Casadevall M,Panés J,Piera C,Jou JM,Pique JM

更新日期：1994-04-01 00:00:00

abstract：:A multitude of opportunistic infections has been documented in virtually every organ system of patients with the acquired immunodeficiency syndrome (AIDS). Prominent among these are infections of the gastrointestinal tract. However, studies of large numbers of patients documenting the frequency of such involvement are...

journal_title：Digestive diseases and sciences

authors： Antony MA,Brandt LJ,Klein RS,Bernstein LH

更新日期：1988-09-01 00:00:00

abstract：UNLABELLED:From studies in 43 patients (17 male, 26 female, mean age 51 years), we compared the analysis of the routine complete "24-hr" ambulatory esophageal pH monitoring study to that of the 16-hr overnight interval (4:00 PM to 8:00 AM). The latter included a major meal with an upright postprandial period and a recu...

journal_title：Digestive diseases and sciences

authors： Dobhan R,Castell DO

更新日期：1992-06-01 00:00:00

abstract：:We assessed the characteristics of muscarinic neural transmission in the vagal inhibitory pathway to the lower esophageal sphincter (LES) of anesthetized opossums. LES relaxation was induced by electrical stimulation of the cervical vagus. Measurements were made of LES relaxation before and after intravenous administr...

journal_title：Digestive diseases and sciences

authors： Gilbert RJ,Dodds WJ

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:To compare the Rosemont criteria, which are graded features chosen by experts in 2007, versus the conventional criteria, which require ≥ 3-5 of the 9 features that are "counted as equal," for the diagnosis of chronic pancreatitis by EUS. METHODS:This is a retrospective cohort study. EUS examinations were sco...

journal_title：Digestive diseases and sciences

authors： D'Souza SL,Anderson MA,Korsnes SJ,Elmunzer BJ,Piraka C,Menees S,Wamsteker EJ,Kwon RS,Scheiman JM,Elta GH

更新日期：2015-12-01 00:00:00

abstract：:The authors have developed a primate model for evaluating cytoprotection against alcohol-induced injury in gastric mucosa pretreated with antiulcer agents. In the present study, groups of squirrel monkeys received either a single oral dose of misoprostol (500 or 200 micrograms/kg), cimetidine (3 or 6 mg/kg), placebo, ...

journal_title：Digestive diseases and sciences

authors： Liss RH,Letourneau RJ,Schepis JP

更新日期：1986-02-01 00:00:00

abstract：:We evaluated the alveolar-arterial oxygen difference (deltaA-a) and the ratio between PaO2 and the fractional concentration of inspired oxygen (P/F) in acute pancreatitis. Eleven patients had mild uncomplicated disease, six showed acute abdominal fluid collections, six had acute abdominal collections and asymptomatic ...

journal_title：Digestive diseases and sciences

authors： Salomone T,Tosi P,Di Battista N,Binetti N,Raiti C,Tomassetti P,Migliori M,Gullo L

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Hepatic encephalopathy is a syndrome whose physiopathology is poorly understood; therefore, current diagnostic tests are imperfect and modern therapy is nonspecific. Particularly, it has been suggested that inflammation plays an important role in the pathogenesis of portal hypertensive encephalopathy in the ...

journal_title：Digestive diseases and sciences

authors： Merino J,Aller MA,Rubio S,Arias N,Nava MP,Loscertales M,Arias J,Arias JL

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:While gastroesophageal reflux disease (GERD) is common in Middle Eastern countries, little data exists on the epidemiology of Barrett's esophagus (BE). AIMS:We aimed to determine the prevalence of BE among patients undergoing esophagogastroduodenoscopy (EGD) in a cohort of Saudi patients. METHODS:We retros...

journal_title：Digestive diseases and sciences

authors： Alsahafi M,Mimish H,Salem F,Hijazi M,Aljahdli E,Jawa H,Bazarah S,Bokhary R,Qari Y,Mosli M

更新日期：2020-08-04 00:00:00

abstract：:Microvesicular steatosis is a potentially severe manifestation of valproic acid hepatotoxicity due to an acquired impairment of mitochondrial function. Tests currently used to investigate mitochondrial fonction are cumbersome and cannot be used routinely. We report on a noninvasive breath test using [13C]methionine fo...

journal_title：Digestive diseases and sciences

authors： Spahr L,Negro F,Rubbia-Brandt L,Marinescu O,Goodman K,Jordan M,Frossard JL,Hadengue A

更新日期：2001-12-01 00:00:00