Simple screening of Bence-Jones proteins from unconcentrated urine.

abstract：INTRODUCTION:Intrahepatic injection of alloantigen prolongs allograft survival and inhibits T-lymphocyte release of both IL-2 and IFN-gamma but not IL-4. This suggests that intrahepatic processing of antigen lead to a predominance of Th2 cell population with inhibition of Th1 cell type. This study examines the effects ...

journal_title：Immunology letters

authors： Chen Y,McKenna GJ,Ong C,Mui AL,Chung SW

更新日期：2002-04-01 00:00:00

abstract：:The basic functions of the immune system are protection from pathogens and maintenance of tolerance to self. The maintenance of commensal microbiota at mucosal surfaces adds a layer of complexity to these basic functions. Recent reports suggest follicular helper T cells (Tfh), a CD4(+) T cell subset specialized to pro...

journal_title：Immunology letters

authors： Winstead CJ

更新日期：2014-12-01 00:00:00

abstract：:When murine BALB/c splenocytes are pretreated for 2 h with different concentrations of 25-hydroxycholesterol (25-HC) or 7 beta-hydroxycholesterol (7-HC), washed and stimulated either with irradiated C57BL/6 splenocytes or with Con A, IL-2 secretion is inhibited in a dose-dependent way as well as the subsequent cell pr...

journal_title：Immunology letters

authors： Richert L,Beck JP,Shinitzky M

更新日期：1986-11-03 00:00:00

abstract：:The carboxy-terminus of the major merozoite surface protein of Plasmodium has been shown to be the target of protective immunity in a number of non-vivax malaria parasite species. In an effort to develop a protective vaccine for Plasmodium vivax, the most prevalent form of human malaria, we expressed in Saccharomyces ...

journal_title：Immunology letters

authors： Kaslow DC,Kumar S

更新日期：1996-07-01 00:00:00

abstract：:This study was to investigate the role of macrophage migration inhibitory factor (MIF) in mouse acute otitis media (AOM), we hypothesize that blocking MIF activity will relieve mouse AOM. A mouse AOM model was constructed by injecting lipopolysaccharide (LPS) into the middle ear of C57BL/6 mice through the tympanic me...

journal_title：Immunology letters

authors： Zhang J,Xu M,Zheng Q,Zhang Y,Ma W,Zhang Z

更新日期：2014-11-01 00:00:00

abstract：:Experimental systemic lupus erythematosus (SLE), similar to that observed after immunization with the human anti-DNA mAb 16/6 Id+, could be induced in mice by injection of 16/6 Id specific T-cell lines. The above T-cell lines were exclusively CD4+ CD8- and the majority of cells expressed the Vbeta8 T-cell receptor (TC...

journal_title：Immunology letters

authors： Ruiz PJ,Waisman A,Mozes E

更新日期：1998-05-01 00:00:00

abstract：:The majority of peripheral blood mononuclear cells (PBMC) from acute-phase infectious mononucleosis (IM) patients express high levels of T10 (CD38) and HLA-DR surface antigens, which are markers characteristic of activated T cells. However, Tac antigen (p55) expression on these cells was not detectable by flow cytomet...

journal_title：Immunology letters

authors： Schmidt C,Burman K,Moss DJ,Ryan J,Burrows SR,Misko IS

更新日期：1989-12-01 00:00:00

abstract：:A major factor in the ability of the placenta to avoid allograft rejection is the differential expression of MHC class I antigens on its surface. Using monoclonal antibodies and the electron microscopic immunogold technique, we have demonstrated that only the pregnancy-associated (Pa) antigen, which carries a broadly ...

journal_title：Immunology letters

authors： Kanbour A,Macpherson TA,Kunz HW,Gill TJ 3rd

更新日期：1987-12-01 00:00:00

abstract：:Dendritic cells (DCs) are very important for the generation of long lasting immune responses against pathogens or the induction of anti-tumor responses. Targeting antigen to dendritic cells via monoclonal antibodies specific for DC cell surface receptors such as DEC205 was shown to elicit potent cellular and humoral i...

journal_title：Immunology letters

authors： Heidkamp GF,Neubert K,Haertel E,Nimmerjahn F,Nussenzweig MC,Dudziak D

更新日期：2010-08-16 00:00:00

abstract：:Immunodeficiencies can lead to alterations of the gut microbiome that render it pathogenic and capable of transmitting disease to naïve hosts. Here, we review the role of Toll-like receptor (TLR) 5, the innate receptor for bacterial flagellin, in immune responses to the normal gut microbiota with a focus its role on a...

journal_title：Immunology letters

authors： Leifer CA,McConkey C,Li S,Chassaing B,Gewirtz AT,Ley RE

更新日期：2014-12-01 00:00:00

abstract：:Studies on natural cytotoxicity of peripheral blood monocytes were conducted in patients with acute viral hepatitis B, patients with chronic aggressive hepatitis etiopathogenically linked to viral hepatitis B, and in asymptomatic carriers of HBs antigen. In the majority of cases of viral hepatitis in the acute stage o...

journal_title：Immunology letters

authors： Kiczka W,Szkaradkiewicz A,Flieger J

更新日期：1985-01-01 00:00:00

abstract：:Forkhead box O1 (FoxO1) has a crucial role in the early B cell development. To understand the functional importance of FoxO1 gene in the early B cell expansion, we established a FoxO1 knockdown model using 70Z/3 pre-B cell line. The FoxO1 knockdown 70Z/3 cells (70Z/3-KD cells) showed the down-regulated expression of i...

journal_title：Immunology letters

authors： Li Z,Zhang N,Hui F,Zahid D,Zheng W,Xu X,Li W

更新日期：2019-12-01 00:00:00

abstract：:Thymocyte development requires an integration of extracellular cues to enforce lineage commitment at multiple defined checkpoints in a stage-specific manner. Critical signals from the pre-TCR, Notch, and the receptor for interleukin-7 (IL-7) dictate cellular differentiation from the CD4(-)CD8(-) (double negative) stag...

journal_title：Immunology letters

authors： Juntilla MM,Koretzky GA

更新日期：2008-03-15 00:00:00

abstract：:Adoptive transfer of multivirus-specific T cell lines (MVST) is an advanced tool for immunotherapy of virus infections after hematopoietic stem cell transplantation (HSCT). Their preparation includes activation of donor virus-specific T cells by the mixture of oligopeptides derived from immunodominant antigens of seve...

journal_title：Immunology letters

authors： Roubalová K,Němečková Š,Kryštofová J,Hainz P,Pumannová M,Hamšíková E

更新日期：2020-12-01 00:00:00

abstract：:Coenzyme Q10 (CoQ10) is a lipid-soluble antioxidant synthesized in human body. This enzyme promotes immune system function and can be used as a dietary supplement. Rheumatoid arthritis (RA) is an autoimmune disease leading to chronic joint inflammation. RA results in severe destruction of cartilage and disability. Thi...

journal_title：Immunology letters

authors： Jhun J,Lee SH,Byun JK,Jeong JH,Kim EK,Lee J,Jung YO,Shin D,Park SH,Cho ML

更新日期：2015-08-01 00:00:00

abstract：:A quantitative approach was applied to the study of in vivo expression of foreign genes introduced into mice by ballistic transfection. Because in some cases one must take into account both the level of synthesized protein and that of antibodies to it, we derived the equation which allows to calculate the exact quanti...

journal_title：Immunology letters

authors： Rodin DV,Kolesnikov VA,Zelenina IA,Zelenin AV,Deyev SM

更新日期：2000-11-01 00:00:00

abstract：:A direct correlation between the constitutive expression of IL-1 alpha and reduced tumorigenicity of fibrosarcomas was observed. This was established in fibrosarcoma cell lines which produce IL-1 alpha 'spontaneously', possibly as an aberration of oncogene-mediated transformation or upon IL-1 alpha gene transfer. In f...

journal_title：Immunology letters

authors： Apte RN,Douvdevani A,Zoller M,White RM,Dvorkin T,Shimoni N,Fima E,Hacham M,Huleihel M,Benharroch D

更新日期：1993-12-01 00:00:00

abstract：:The binding of anti-IgM IgG to human monoclonal IgM has been studied calorimetrically and results have been compared with parallel turbidity measurements of the same reaction. In the first series of experiments using the flow calorimeter equipped with a mixing cell, varied flow rates gave identical values for the ther...

journal_title：Immunology letters

authors： Rialdi G,Raffanti S

更新日期：1984-01-01 00:00:00

abstract：:We have reported that a cell line, KML1, obtained from lymph node cells of a 16-week-old female MRL/Mp-lpr/lpr (MRL/1) mouse produces a soluble factor(s) that promotes formation of anti-single-stranded (ss) DNA antibodies by cultures of spleen cells from old MRL/l mice (greater than 16 weeks old). Detailed examination...

journal_title：Immunology letters

authors： Kanai Y,Isonishi S,Katagiri T,Koizumi T,Miura K,Kurosawa Y

更新日期：1990-03-01 00:00:00

abstract：:Interleukin 1 beta (IL1 beta) is an inducible polypeptide with many roles in host defence and homoeostasis. It has also been implicated as a mediator of infectious, inflammatory and autoimmune diseases, and the kinetics of its production are relevant to an understanding of the pathogenesis of these conditions. We repo...

journal_title：Immunology letters

authors： di Giovine FS,Symons JA,Duff GW

更新日期：1991-08-01 00:00:00

abstract：:The tryptophan fluorescence properties of two different peptide complexes of the single-chain H-2Kd (SC-Kd) were studied by means of the single-photon counting technique. The latter enables time-resolved measurements of fluorescence intensity and anisotropy decay parameters relevant to structural and dynamic propertie...

journal_title：Immunology letters

authors： Dittes K,Gakamsky DM,Haran G,Haas E,Ojcius DM,Kourilsky P,Pecht I

更新日期：1994-05-01 00:00:00

abstract：:Screening of expression cDNA libraries derived from human neoplasms with autologous sera (SEREX) is an established method for defining antigens immunogenic in individual cancer patients. Although the majority of SEREX-derived cDNA clones encode autoantigens, some of them represent shared cancer antigens with cancer-re...

journal_title：Immunology letters

authors： Lagarkova MA,Koroleva EP,Kuprash DV,Boitchenko VE,Kashkarova UA,Nedospasov SA,Shebzukhov YV

更新日期：2003-01-02 00:00:00

abstract：:Wistar rats submitted to 3 intravenous (i.v.) or intraperitoneal (i.p.) immunizations with saline extract of rat male accessory glands (RAG) associated to liposomes developed a delayed type hypersensitivity (DTH) response to RAG after the first immunization, a remission state after the second immunization and a specif...

journal_title：Immunology letters

authors： Correa SG,Riera CM

更新日期：1991-04-01 00:00:00

abstract：:In order to directly demonstrate the roles of CD8(+) T lymphocytes in non-human primates, in vivo depletion of the CD8(+) T cells by administration of a CD8-specific monoclonal antibody (mAb) is one of the crucial techniques. Recently, the common marmoset (Callithrix jacchus), which is classified as a New World monkey...

journal_title：Immunology letters

authors： Yoshida T,Suzuki S,Iwasaki Y,Kaneko A,Saito A,Enomoto Y,Higashino A,Watanabe A,Suzuki J,Inoue K,Kuroda T,Takada M,Ito R,Ito M,Akari H

更新日期：2013-07-01 00:00:00

abstract：:T cells recognize with a single receptor both a product of antigens processed by antigen presenting cells (APC1) and a self-marker molecule, encoded by the major histocompatibility complex (MHC, a property termed MHC-restricted recognition of antigen). During their differentiation in the thymus, T cells "learn" what t...

journal_title：Immunology letters

authors： Marusić-Galesić S,Pavelić K

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a non-specific inflammation, which involves the airways, lung parenchyma and pulmonary vessels. The inflammation causes the activation of inflammatory cells and the release of various inflammatory mediators such as interleukin-1 beta, interleukin-6 and tumor ne...

journal_title：Immunology letters

authors： Singh S,Verma SK,Kumar S,Ahmad MK,Nischal A,Singh SK,Dixit RK

更新日期：2018-04-01 00:00:00

abstract：:To elucidate the role of macrophage migration inhibitory factor (MIF) in ocular inflammation, we examined the localization of MIF in the normal anterior uveal tract of rats. Immunohistochemistry using an anti-MIF antibody revealed that MIF was present in non-pigment epithelial cells of the ciliary body and the epithel...

journal_title：Immunology letters

authors： Matsuda A,Kotake S,Tagawa Y,Matsuda H,Nishihira J

更新日期：1996-10-01 00:00:00

abstract：:The aim of the present letter is to propose a rational nomenclature for the d-mannose-binding lectin from seeds of Artocarpus integrifolia. It is justified by the existing confusion in the literature concerning the trivial names used until now to designate the lectin and by the increasing interest in its biomedical ap...

journal_title：Immunology letters

authors： Pereira-da-Silva G,Roque-Barreira MC,Van Damme EJ

更新日期：2008-08-15 00:00:00

abstract：:Granulomatous inflammation around parasite eggs is the prominent lesion in human schistosomiasis. Studies have suggested the involvement of a series of suppressive mechanisms in the control of this reaction, such as macrophages, cytokines, idiotypic interactions and immune complexes (IC). The studies examine the role ...

journal_title：Immunology letters

authors： Rezende SA,Gollob KJ,Correa-Oliveira R,Goes AM

更新日期：1998-06-01 00:00:00

abstract：:Nervous and immune systems share specific recognition molecules for signals that originate in both systems. The information substances are polypeptides and their receptors. They comprise the multi-directional information exchange network whereby brain and nervous system function including mood and emotion can be integ...

journal_title：Immunology letters

authors： Wiedermann CJ

更新日期：1987-12-01 00:00:00