Abstract:
:The development of more selective chemotherapeutic agents for benign treatments of malicious diseases is highly desirable. In recent years model systems for the release of small molecule drugs from nucleic acid conjugates by templated chemical or photochemical reactions have been designed. Common for these systems is that the stoichiometric or catalytic drug release is controlled by the highly selective hybridization between complementary strands of nucleic acids. Herein, the concepts of the new field of nucleic acid templated release reactions are outlined.
journal_name
ChemMedChemjournal_title
ChemMedChemauthors
Jacobsen MF,Cló E,Mokhir A,Gothelf KVdoi
10.1002/cmdc.200700013subject
Has Abstractpub_date
2007-06-01 00:00:00pages
793-9issue
6eissn
1860-7179issn
1860-7187journal_volume
2pub_type
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