Effect of dibromothymoquinone (DBMIB) on reduction rates of Photosystem I donors in intact chloroplasts.

abstract：:Delipidated proteins from a fraction of mouse lung homogenate enriched for lamellar bodies of type 2 pneumocytes were characterized by a combination of gel filtration and enzyme immunoassay for the presence of a surfactant-associated antigen. Immunoreactivity was associated with a protein of Mr 250-270,000 as well as ...

journal_title：Biochemical and biophysical research communications

authors： Kumar RK,Smith GJ,Truscott JY,Hristoforidis CP,Lykke AW

更新日期：1986-09-30 00:00:00

abstract：:We here report that aging increases expression of endothelin-1 and NO synthases in the vasculature and kidney of normotensive rats in vivo. Expression of preproendothelin-1 mRNA was quantified by RT-PCR and in situ hybridization, and endothelin-1 protein was determined by radioimmunoassay/HPLC. Vascular mRNA expressio...

journal_title：Biochemical and biophysical research communications

authors： Goettsch W,Lattmann T,Amann K,Szibor M,Morawietz H,Münter K,Müller SP,Shaw S,Barton M

更新日期：2001-01-26 00:00:00

abstract：:Lactate dehydrogenase (LDH) is a glycolytic enzyme that catalyzes the final step of glycolysis and produces NAD+. In somatic cells, LDH forms homotetramers and heterotetramers that are encoded by two different genes: LDHA (skeletal muscle type, M) and LDHB (heart type, H). Analysis of LDH isozymes is important for und...

journal_title：Biochemical and biophysical research communications

authors： Goto T,Sugawara K,Nakamura S,Kidokoro SI,Wakui H,Nunomura W

更新日期：2016-10-28 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) is a small neuropeptide, which exerts pleiotropic functions. Based on its immunomodulatory, secretory, and possibly trophic effects, VIP is a valuable candidate molecule for the management of autoimmune disease. The purpose of this study was to develop a recombinant viral vector cap...

journal_title：Biochemical and biophysical research communications

authors： Lodde BM,Delporte C,Goldsmith CM,Tak PP,Baum BJ

更新日期：2004-06-18 00:00:00

abstract：:IRE1α (Inositol-requiring enzyme 1 α), an endoplasmic reticulum (ER)-resident sensor for mammalian unfolded protein response, is a type I transmembrane protein which has a bifunctional enzyme containing kinase and RNase domains. Although the luminal domain and cytosolic domain of IRE1α are thought to play crucial role...

journal_title：Biochemical and biophysical research communications

authors： Cho H,Lamarca R,Chan C

更新日期：2012-11-02 00:00:00

abstract：:Reactive oxygen species (ROS) are highly reactive and directly attack surrounding biomolecules to deteriorate cellular and tissue functions. Meanwhile, ROS also serve as signaling mediators to upregulate pro-inflammatory cytokine expression via activation of the nuclear factor kappa B signaling pathway, and the increa...

journal_title：Biochemical and biophysical research communications

authors： Hu D,Li D,Shigeta M,Ochi Y,Okauchi T,Neyama H,Kabayama S,Watanabe Y,Cui Y

更新日期：2021-01-08 00:00:00

abstract：:A mouse hepatoma cell line, Hepa-1, is highly sensitive to the toxic effects of Aflatoxin B1 (AFB1). Half maximal survival (LD50) of cells occurs at 0.068 ug AFB1/ml. Benzo(a)anthracene, which induces aryl hydrocarbon hydroxylase and cytochrome P1-450 in Hepa-1, causes a slight increase in the toxicity of AFB1 (LD50 =...

journal_title：Biochemical and biophysical research communications

authors： Kärenlampi SO

更新日期：1987-06-15 00:00:00

abstract：:Factors affecting Ins(1,3,4,5)P4-mediated nuclear Ca2+ uptake are investigated, which include Ins(1,3,4,5)P4 receptor ligand specificity and free external Ca2+ concentrations. Among various inositol phosphates examined, Ins(1,3,4,5)P4, Ins(3,4,5,6)P4, and Ins(1,3,4,5,6)P5 can also stimulate 45Ca2+ influx into isolated...

journal_title：Biochemical and biophysical research communications

authors： Hsu AL,Lu PJ,Chen CS

更新日期：1998-02-24 00:00:00

abstract：:Taking advantage of the defined acceptor specificity of rat liver alpha 2,6-sialyltransferase, N-linked Gal beta 1,4GlcNAc-sequences of glycoconjugates at the plasma membrane of viable human erythrocytes and lymphoblastic IM-9 cells were modified to terminate in three NeuAc analogues endowed with special biochemical p...

journal_title：Biochemical and biophysical research communications

authors： Kosa RE,Brossmer R,Gross HJ

更新日期：1993-02-15 00:00:00

abstract：:A DNA endonuclease complex which recognizes predominantly pyrimidine dimers in UVC irradiated DNA has been isolated from the chromatin of normal human and xeroderma pigmentosum, complementation group D (XPD) lymphoblastoid cells. The activity of the normal complex on UVC irradiated DNA was increased approximately 2.5 ...

journal_title：Biochemical and biophysical research communications

authors： Parrish DD,Feng X,Lambert MW

更新日期：1992-12-15 00:00:00

abstract：:Glucocorticoids inhibit prostaglandin biosynthesis by inducing the formation of lipocortins. In human amnion cells dexamethasone elicited a concentration-dependent increase in prostaglandin production and raised intracellular lipocortin 1 concentrations. Dexamethasone could also potentiate the epidermal growth factor ...

journal_title：Biochemical and biophysical research communications

authors： Mitchell MD,Lytton FD,Varticovski L

更新日期：1988-02-29 00:00:00

abstract：:While Wnt and Ras signaling pathways are activated during progression of colorectal cancers, many of their important downstream targets remain to be elucidated. The gastrin gene encodes for a family of peptide growth factors that are commonly upregulated in colorectal neoplasia. Previously, we showed that the Wnt sign...

journal_title：Biochemical and biophysical research communications

authors： Chakladar A,Dubeykovskiy A,Wojtukiewicz LJ,Pratap J,Lei S,Wang TC

更新日期：2005-10-14 00:00:00

abstract：:mRNA levels of mitogen-activated protein kinase phosphatases, MKP-1 and MKP-2, were determined during chemical hepatocarcinogenesis and during regeneration of rat liver. In chemical hepatocarcinogenesis, the mRNA levels of MKP-1 were increased in primary hepatomas but decreased in rat ascites hepatomas as compared wit...

journal_title：Biochemical and biophysical research communications

authors： Yokoyama A,Karasaki H,Urushibara N,Nomoto K,Imai Y,Nakamura K,Mizuno Y,Ogawa K,Kikuchi K

更新日期：1997-10-29 00:00:00

abstract：:The calmodulin-like domain of calpain is important for the association of the calpain large and small subunits. We expressed the calmodulin-like domains of the large subunits of rabbit mu- and m-calpains and their small subunits in E. coli and purified them to homogeneity. Unlike the full-length subunits, the calmodul...

journal_title：Biochemical and biophysical research communications

authors： Suo S,Koike H,Sorimachi H,Ishiura S,Suzuki K

更新日期：1999-04-02 00:00:00

abstract：:Microglia, brain macrophages, are thought to be the primary target of HIV-1 infection in the brain, because they exclusively express the CD4 antigen which is effectively used for viral entry. The expression of CD4 mRNA in cultured microglia could be detected by the reverse-PCR method. Using this and immunohistochemica...

journal_title：Biochemical and biophysical research communications

authors： Sawada M,Suzumura A,Marunouchi T

更新日期：1992-12-15 00:00:00

abstract：:In this study, we investigated hybrid and non-hybrid actomyosin models including key contractile proteins: actin, myosin, and tropomyosin. These proteins were isolated from the rabbit skeletal muscle and the catch muscle of the mussel Crenomytilus grayanus. Our results confirmed literature data on an unusual ability o...

journal_title：Biochemical and biophysical research communications

authors： Shelud'ko NS,Vyatchin IG,Lazarev SS,Shevchenko UV

更新日期：2015-08-21 00:00:00

abstract：:Microsomal vesicles prepared from rat adipocytes were immuno-adsorbed to formaldehyde-fixed Staphylococcus aureus cells (Pansorbin) coated with anti-human-erythrocyte-glucose-transporter IgG. More than 75% of the glucose transporter detected was precipitated. The glucose transporter was about 10-fold enriched by the a...

journal_title：Biochemical and biophysical research communications

authors： Ezaki O,Bono N,Itakura H,Kasahara M

更新日期：1989-03-31 00:00:00

abstract：:Previous reports have shown that 12-0-tetradecanoylphorbol-13-acetate can activate phospholipase D in human peripheral blood mononuclear cells as measured by an enzyme-catalyzed transphosphatidylation reaction (phosphatidylethanol formation). In the present study, the mononuclear cells were fractionated by two procedu...

journal_title：Biochemical and biophysical research communications

authors： Kinsky SC,Loader JE,Benedict SH

更新日期：1989-07-31 00:00:00

abstract：:BHLHB2/DEC1 is a transcription factor implicated in cell proliferation, apoptosis, and metabolism, and is also known to play an important role in the regulation of the mammalian circadian rhythm. However, its precise role in metabolism remains unclear. We investigated the link between BHLHB2 and ChREBP, a glucose-acti...

journal_title：Biochemical and biophysical research communications

authors： Iizuka K,Horikawa Y

更新日期：2008-09-12 00:00:00

abstract：:Lysophosphatidylcholine (lyso-PC), a biologically active phospholipid, appears to modulate various endothelial cell functions through tyrosine kinase-dependent signaling pathways. In cultured bovine aortic endothelial cells (BAEC), we have found that a 130 kDa protein (p130) was rapidly tyrosine phosphorylated within ...

journal_title：Biochemical and biophysical research communications

authors： Ochi H,Kume N,Nishi E,Moriwaki H,Masuda M,Fujiwara K,Kita T

更新日期：1998-02-24 00:00:00

abstract：:In order to search for novel estrogen-responsive genes, we performed serial analysis of gene expression (SAGE) for estrogen-treated MCF-7 human breast cancer cells. SAGE analysis of 31,000 and 30,856 tags from non-treated and 17 beta-estradiol (E2)-treated cells for 24 h, respectively, facilitated the identification o...

journal_title：Biochemical and biophysical research communications

authors： Inadera H,Hashimoto S,Dong HY,Suzuki T,Nagai S,Yamashita T,Toyoda N,Matsushima K

更新日期：2000-08-18 00:00:00

abstract：:The c-myc oncogene is implicated in normal growth and differentiation processes. Human cell lines IM9 and HepG2 stably cultured at "low" glucose concentrations (5.5 mM) show c-myc mRNA levels 3-4 times higher than cells cultured at "high" glucose concentrations (25 nM). D-fructose (a metabolizable exose) substitutes f...

journal_title：Biochemical and biophysical research communications

authors： Briata P,Laurino C,Gherzi R

更新日期：1989-12-29 00:00:00

abstract：:Various subclasses of messenger ribonucleoprotein particles were prepared from free cytoplasmic and polysome fractions of rat liver on the basis of the homopolymeric content of the constituent RNA's. Two major proteins were evident in the free cytoplasmic preparations: the poly(A)-binding protein was the major constit...

journal_title：Biochemical and biophysical research communications

authors： Ford G,Nichols JL

更新日期：1984-05-16 00:00:00

abstract：:The apicomplexan Toxoplasma gondii, an obligate intracellular parasite, can infect humans and a wide range of vertebrates. Following oral infection, the parasite invades tissues by crossing non-permissive biological barriers such as the placenta or the blood-brain barrier. But the molecular mechanisms underlying migra...

journal_title：Biochemical and biophysical research communications

authors： Buache E,Garnotel R,Aubert D,Gillery P,Villena I

更新日期：2007-07-27 00:00:00

abstract：:Recombinant human GM-CSF (rhGM-CSF) from yeast has been clinically applied to immunosuppressed patients. The production of suspension-cultured rice-cell-derived rhGM-CSF (rrhGM-CSF), which has a longer blood clearance time and the same bioactivity as yeast-derived rhGM-CSF, and the analysis of its N-glycans have been ...

journal_title：Biochemical and biophysical research communications

authors： Kim J,Park H,Park BT,Hwang HS,Kim JI,Kim DK,Kim HH

更新日期：2016-10-14 00:00:00

abstract：:The glycoprotein processing inhibitors bromoconduritol and N-methyl-1-deoxynojirimycin inhibit myoblast fusion and differentiation, suggesting the critical involvement of one or more glycoproteins in the control of skeletal myogenesis. In the present study we have examined the effect of inhibitors of glycoprotein proc...

journal_title：Biochemical and biophysical research communications

authors： Trudel GC,Holland PC

更新日期：1992-04-15 00:00:00

abstract：:Cell cycle variations in ADP-ribosylation of nuclear scaffold proteins were determined. Nuclei of synchronized cells were isolated and labeled with [32P]NAD before nuclear scaffolds were obtained by digestion of DNA with DNase I and extraction of proteins with 2M NaCl. Autoradiograms revealed the three groups of "lami...

journal_title：Biochemical and biophysical research communications

authors： Adolph KW,Song MK

更新日期：1985-01-31 00:00:00

abstract：:Endochondral bone formation is an important process in development and growth of the skeleton; still many of the mechanisms of growth cartilage remain unknown. The aim of this study was to identify genes specifically expressed in growth cartilage by constructing a subtraction cDNA library of the articular-epiphyseal c...

journal_title：Biochemical and biophysical research communications

authors： Johannessen MK,Skretting G,Ytrehus B,Røed KH

更新日期：2007-03-23 00:00:00

abstract：:Alkaline elastase YaB, produced by alkalophilic Bacillus YaB, is an extracellular serine protease having 55% homology to subtilisin BPN' and thus could be called subtilisin YaB. It is synthesized as a 378-amino acid preproenzyme and secreted into the culture medium as a 265-amino acid mature protease. To examine if th...

journal_title：Biochemical and biophysical research communications

authors： Chang YC,Kadokura H,Yoda K,Yamasaki M

更新日期：1996-02-15 00:00:00

abstract：:Downregulation of the LATS1 tumour suppressor protein kinase contributes to tumour formation in mammals and flies. Strikingly, the tumour suppressor activity depends on the interaction with Dmob (Drosphila Mps1-One binder) in Drosophila melanogaster. Recently, human LATS1 was reported to interact with human MOB1 (hMOB...

journal_title：Biochemical and biophysical research communications

authors： Hergovich A,Schmitz D,Hemmings BA

更新日期：2006-06-23 00:00:00