Linkage disequilibrium in Bougainville Island.

Abstract:

:Linkage disequilibria are estimated for three 2-locus systems in 18 samples from Bougainville Island, Solomon Islands. The systems are haptoglobin, acid phosphatase and MN blood group. The disequilibria are estimated two ways: by maximum likelihood (ML) and by the covariance between the non-alleles. Though seven of the 52 ML estimates are statistically different than zero, none of the covariance estimates are significant. We conclude that because linkage disequilibrium for loosely linked loci is a small quantity and because the sample sizes for most populations studied by anthropologists are small, linkage disequilibrium will not be a useful parameter for the study of natural selection in these populations.

journal_name

Am J Phys Anthropol

authors

Cadien JD,Hassett MJ,Friedlaender JS

doi

10.1002/ajpa.1330480305

subject

Has Abstract

pub_date

1978-03-01 00:00:00

pages

297-304

issue

3

eissn

0002-9483

issn

1096-8644

journal_volume

48

pub_type

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