Abstract:
UNLABELLED:Cholesteatoma may cause bone erosion, with high morbidity and mortality rates. Tumor necrosis factor-alpha (TNF-a) is one of the main cytokines involved in this process. Our goal was to evaluate the role of TNF-a in Bone Resorption and its effect on cholesteatoma. MATERIAL AND METHODS:analysis and critical literature review. RESULTS:Different studies have demonstrated that TNF-a is capable of causing bone erosion. It may stimulate the differentiation and maturation of osteoclasts or it may act on the bone matrix, exposing it to the action of the osteoclasts. It is possible to inhibit TNF-a, reducing its effects and prevent bone loss in illnesses such as rheumatoid arthritis,and there has been no specific investigation regarding cholesteatomas. All studies agree on the importance of TNF-a in the bone resorption process present in cholesteatomas, and on the degree of destruction observed; however, there is no consensus as to its location. These differences are probably due to receptor site. CONCLUSION:TNF-a, present in cholesteatomas, promotes bone resorption, along with other cytokines (RANKL and IL-1) related to complications.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Vitale RF,Ribeiro Fde Adoi
10.1016/s1808-8694(15)31133-2subject
Has Abstractpub_date
2007-01-01 00:00:00pages
117-21issue
1eissn
1808-8694issn
1808-8686pii
S1808-8694(15)31133-2journal_volume
73pub_type
杂志文章,评审abstract:INTRODUCTION:Several approaches have been tried for the treatment of tinnitus, from cognitive-behavioral therapies and sound enrichment to medication. In this context, antioxidants, widely used in numerous areas of medicine, appear to represent a promising approach for the control of this symptom, which often is poorly...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.bjorl.2015.04.016
更新日期:2016-05-01 00:00:00
abstract:UNLABELLED:The neck is vulnerable to trauma because of vital structures and possible major injuries with high morbidity and mortality rates. AIM:To evaluate the outcome in patients with penetrating cervical wounds. METHODS:The medical registries of 39 patients were analyzed retrospectively from 2001 to 2009. Penetrat...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1590/s1808-86942011000100020
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Rhinosinusitis constitutes an important health problem, with significant interference in personal, professional, and social functioning. This study presents the validation process of the Portuguese version of the RhinoQOL, to be used as a routine procedure in the assessment of patients with chronic rhinosi...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.08.015
更新日期:2015-11-01 00:00:00
abstract:UNLABELLED:The possibility of needing a combined access, with neck and chest incisions makes the treatment of substernal goiter a challenge both in the pre-op and the intraoperative. We hereby, discuss a standardization of the surgical technique to minimize the need for a chest approach, making the substernal goiter a ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30774-6
更新日期:2009-03-01 00:00:00
abstract:INTRODUCTION:Chronic rhinosinusitis with nasal polyps is a multifactorial disease entity with an unclear pathogenesis. Contradictory data exist in the literature on the potential implication of viral elements in adult patients with chronic rhinosinusitis. OBJECTIVE:To compare the prevalence of human herpes viruses (1-...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.08.010
更新日期:2015-11-01 00:00:00
abstract:UNLABELLED:Ototoxicity of organic solvents can affect the hearing system up to the cochlea level and the central structures of hearing. OBJECTIVE:To evaluate the neurophysiological integrity of the hearing system in subjects exposed to fuels using ABR. METHOD:Prospective study. We evaluated attendants from three gas ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20120035
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Calcium is vital for the functioning of the inner ear hair cells as well as for the neurotransmitter release that triggers the generation of a nerve impulse. A reduction in calcium level could therefore impair the peripheric vestibular functioning. However, the outcome of balance assessment has rarely been...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.08.013
更新日期:2018-01-01 00:00:00
abstract:UNLABELLED:Upper respiratory tract infections are the most common causes of medical visits in children and adults, demanding massive use of antibiotics. Bacterial resistance caused by beta-lactamase is one of the most serious problems in this matter. Sultamicillin, a double pro-drug of Ampicillin/Sulbactan, is a potent...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/s1808-8694(15)30041-0
更新日期:2006-01-01 00:00:00
abstract:UNLABELLED:The association between hearing and balance disorders with migraine is known since the times of the ancient Greeks, when Aretaeus from Cappadocia in 131 B.C, made an accurate and detailed description of this occurrence during a migraine episode. We present a broad review of migraine neurotological manifestat...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s1808-8694(15)30611-x
更新日期:2008-07-01 00:00:00
abstract:INTRODUCTION:The real number of COVID-19 cases may be underestimated since several countries have difficulty offering laboratory tests for all the population. Therefore, finding a symptom with a high predictive value would help in diagnostic and isolation strategies. OBJECTIVE:To correlate the sudden loss of the sense...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2020.05.002
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:There is a strong association between vertigo and migraine. Vestibular migraine (VM) was described in 1999, and diagnostic criteria were proposed in 2001 and revised in 2012. OBJECTIVE:To compare the diagnostic criteria for VM proposed in 2001 with 2012 criteria with respect to their diagnostic power and ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.07.007
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION:Treatments used in head and neck cancer greatly impact the physical, psychological and functional state of patients. Evaluation of quality of life has become an integral part of the treatment. OBJECTIVE:This retrospective study evaluates features involved in changes in quality of life after major surgery ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.10.013
更新日期:2016-09-01 00:00:00
abstract:AIM:To assess whether or not the parameters of fixed and randomized saccadic movements, of pendular tracking and of optokinetic nystagmus in the digital vectonystagmography may show abnormalities in patients with possible diagnosis of peripheral vestibular dysfunction. METHOD:60 patients with dizziness of peripheral v...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30977-0
更新日期:2006-05-01 00:00:00
abstract:UNLABELLED:Children dysphonia studies have reported an incidence of 4.4 to 30.3%. GOALS:To establish the prevalence of dysphonia in children, based on the opinion of the parents, acoustic and vocal-perceptual assessments, associated symptoms, risk factors and videolaryngoscopy findings. MATERIALS AND METHODS:The pare...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract:UNLABELLED:Mandibular cross-sectional deficiency is a dentofacial defect in connection with the narrowing of the mandibular arch width. This abnormality is a significant etiopathogenic factor and it is often associated with nasal breathing difficulties. This atresia may be treated through Rapid Maxillary Expansion or S...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1016/S1808-8694(15)31388-4
更新日期:2008-09-01 00:00:00
abstract:INTRODUCTION:Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma (SCC). Because of its rarity, both clinical and prognostic features of this variant are not well known. OBJECTIVE:In this study, we aimed to determine the frequency of BSCC and other SCC variants among all laryngeal SCC c...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2014.02.005
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Percutaneous drains can be associated with several complications, including infection, fistula formation, discomfort and prolonged hospitalization. OBJECTIVE:The aim of this study was to evaluate the safety of submandibular gland excision without the use of surgical drains. METHODS:We analyzed the surger...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2019.04.010
更新日期:2020-01-01 00:00:00
abstract:AIM:To co-relate the use of hormonal contraceptives with positive Auditory and Vestibular alterations. METHODS:medical history taking, audiometric test and vestibular test was applied to 60 women between the ages of 14 and 35 years old, and 30 of these women are on oral hormonal contraceptive consisting of Estrogen an...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30967-8
更新日期:2006-05-01 00:00:00
abstract:UNLABELLED:To identify the grade and evolution of dysphagia and dysphonia in patients undergoing supracricoid laringectomy, and to study the association of these findings with clinical and surgical variables. METHOD:The study included 22 cases undergoing supracricoid laringectomy at the Head and Neck Surgery and Otola...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31059-4
更新日期:2007-03-01 00:00:00
abstract:INTRODUCTION:It has become common to use scales to measure the degree of involvement of facial paralysis in phonoaudiological clinics. OBJECTIVE:To analyze the inter- and intra-rater agreement of the scales of degree of facial paralysis and to elicit point of view of the appraisers regarding their use. METHODS:Cross-...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2014.04.005
更新日期:2015-05-01 00:00:00
abstract:UNLABELLED:Laryngeal microsurgery is a kind of treatment for various laryngeal diseases. Because of the need of long instruments and delicate maneuvers, involuntary movements represent relevant difficulty and may be responsible for unintended post-operative results. AIM:This study proposes a new stabilization system, ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::Squamous papillomas are benign neoplasms. The occurrence of middle ear squamous papilloma is rare. It is usually associated with nasosinusal pathology. The authors report a case of middle ear squamous papilloma and discuss its diagnostic aspects. ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31344-6
更新日期:2005-05-01 00:00:00
abstract:UNLABELLED:Parkinson's disease affects the central nervous system resulting in voice quality alterations. It is typically resistant to drug therapy and often persists despite extensive behavioural speech and language therapy. Previous findings show that masking noise will produce a consistent increase in voice intensit...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30129-4
更新日期:2007-09-01 00:00:00
abstract:UNLABELLED:Hearing aid fitting involves numerous issues that must be investigated - from the device supply all the way to results achieved with it in order to improve its results in planning Auditory Health Care. AIMS:to verify difficulties related to device use, batteries and ear molds handling, the very characterist...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/S1808-8694(15)31170-8
更新日期:2007-11-01 00:00:00
abstract:INTRODUCTION:Supratracheal laryngectomy has been described as a surgical procedure for glottic or supraglottic cancer extending to the subglottic region and/or involving the cricoarytenoid joint, aiming to preserve laryngeal function (breathing, phonation and swallowing), without diminishing locoregional cancer control...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2019.04.004
更新日期:2020-01-01 00:00:00
abstract:UNLABELLED:Balance disorders affect social, family and professional activities. Vestibular rehabilitation can reduce the impact of these disorders on the quality of life of individuals with vertigo. AIM:to study the influence of vestibular rehabilitation on the quality of life of individuals, correlating it with gende...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract:INTRODUCTION:Auditory steady-state responses (ASSR) are an important tool to detect objectively frequency-specific hearing thresholds. Pure-tone audiometry is the gold-standard for hearing evaluation, although sometimes it may be inconclusive, especially in children and uncooperative adults. AIM:Compare pure tone thre...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20140009
更新日期:2014-01-01 00:00:00
abstract:UNLABELLED:Cleft lip and/or palate represent the most common congenital anomaly of the face. AIM:To describe the correlation between non-syndromic cleft lip and/or palate and gender, and its severity in the Brazilian population. METHODS:Cross-sectional study, between 2009 and 2011, in a sample of 366 patients. The da...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20120018
更新日期:2012-10-01 00:00:00
abstract:UNLABELLED:The treatment of tinnitus is still a challenge. Acupuncture is recommended for the relief of tinnitus in traditional Chinese Medicine, although scientific evidence is lacking. AIM:The aim of this study was to assess the effect of acupuncture on the cochlear function in patients with tinnitus by analyzing ot...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30119-1
更新日期:2007-09-01 00:00:00
abstract:UNLABELLED:Previous studies suggest that there is an excellent correlation between the morphology and dimensions of ear structures in sheep and human beings. AIM:To analyze and describe the histology of structures inside the temporal bone in sheep. MATERIAL AND METHODS:A total of 307 slides obtained from vertical and...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1590/s1808-86942011000300003
更新日期:2011-06-01 00:00:00