Abstract：
:Down syndrome is the most common chromosomal abnormality affecting numerous organs, including the skin. Our aim was to study mucocutaneous findings in this syndrome. To do so, 100 children with Down syndrome attending Schools for Children with Special Educational Needs and centers affiliated to the Welfare and Rehabilitation Organization in two provinces of Iran were thoroughly examined for skin and mucosal lesions. Their mean age was 11.2 years (3-20 years). Mucocutaneous findings were noted in 61. These were as follows (in decreasing order)--fissured tongue 28%, hypertrophy of tongue papilla 22%, premature graying 14%, cheilitis 13%, xerosis 12%, alopecia areata 11%, palmoplantar hyperkeratosis 10%, syringoma 6%, keratosis pilaris 4%, geographic tongue 4%, trichotillomania 4%, vitiligo 3%, seborrheic dermatitis 3%, livedo reticularis 2%. No instances of atopic dermatitis or skin infections and infestations were noted. The lack of atopic dermatitis in our series was in concordance with its low prevalence reported in recent articles. Improved hygiene due to patient care at home may underlie the absence of infections. With the increasing survival rate of those with Down syndrome, physicians should be more aware of the skin findings seen so frequently in this genetic disorder.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Daneshpazhooh M,Nazemi TM,Bigdeloo L,Yoosefi Mdoi
10.1111/j.1525-1470.2007.00412.xsubject
Has Abstractpub_date
2007-05-01 00:00:00pages
317-20issue
3eissn
0736-8046issn
1525-1470pii
PDE412journal_volume
24pub_type
杂志文章abstract：:Lichen striatus is a common childhood eruption, but only rare reports link cutaneous manifestations and onychodystrophy. We report a case of lichen striatus and onychodystrophy in a 12-year-old girl, only the eighth such patient in the dermatologic literature. Nail changes may precede the rash of lichen striatus and s...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.1993.tb00399.x
更新日期：1993-12-01 00:00:00
abstract：:Loose anagen hair syndrome (LAHS) is a condition of sparse, short hair that is easily and painlessly extracted from the scalp. Since it was first described in the 1980s, it is considered a rare, sporadic condition found predominantly in females. Since then, there have been multiple reports of LAHS occurring in familie...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.2010.01186.x
更新日期：2010-07-01 00:00:00
abstract：:Diaper dermatitis is the most common contact eczema present in early childhood. The main cause is an irritant reaction to urine and feces, which is facilitated by the occlusive conditions under the diaper, leading to hyperhydration of the stratum corneum (diaper dermatitis). In addition, diaper pressure and friction c...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.13484
更新日期：2018-03-01 00:00:00
abstract：:Although the U.S. pediatric skin care market is a $1.7 billion industry, little is known regarding the usage pattern of skin care products in very young children. We have begun to recognize that common over-the-counter skin care products may have positive or negative effects on skin barrier function. Thus, knowing wha...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.12424
更新日期：2014-11-01 00:00:00
abstract：:The first report of spinous follicular lichen nitidus with perifollicular granulomas was by Madhok and Winkelmann in 1988. Since this report, a few cases of follicular or periappendageal lichen nitidus have been described, in a more localized form or without perifollicular granulomas. We describe a 5-year-old girl wit...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.2012.01789.x
更新日期：2013-05-01 00:00:00
abstract：:Throughout history, individuals have had a myriad of dermatologic conditions characterized as chronic pruritic dermatoses. The term atopic dermatitis was not coined until the early 20th century. Many diseases typical of this condition were reported using a variety of eponyms and descriptive terms. Even as the incidenc...
journal_title：Pediatric dermatology
pub_type： 历史文章,杂志文章,评审
doi：10.1111/pde.12853
更新日期：2016-07-01 00:00:00
abstract：:A 40-year-old man and his 6-year-old only son had numerous, firm papulonodular lesions on their faces. Their medical histories were unremarkable and no family consanguinity was recorded. Surgical excision of several lesions was performed on each patient. All the lesions were solid tumors with the characteristic histop...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.1995.tb00195.x
更新日期：1995-12-01 00:00:00
abstract：:Condylomata acuminata (CA), or anogenital warts, are typically benign lesions caused by human papillomavirus infection. Although they are rare, immunocompromised individuals are at a higher risk of CA undergoing transformation into invasive anal squamous cell carcinoma (SCC). These patients need aggressive evaluation ...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.12617
更新日期：2015-07-01 00:00:00
abstract：:Hand-foot-mouth disease (HFMD) is a contagious enteroviral infection occurring primarily in children and characterized by a vesicular palmoplantar eruption and erosive stomatitis. Nail matrix arrest has been associated with a variety of drug exposures and systemic illnesses, including infections, and may result in a v...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1046/j.1525-1470.2000.01702.x
更新日期：2000-01-01 00:00:00
abstract：:Bullous pemphigoid (BP) is the most common autoimmune blistering disease affecting the elderly but is quite rare in childhood. The majority of pediatric cases have been reported during early childhood. Adolescence is divided into three phases: early (10-13 years), middle (14-17), and late (18-21). This review aimed to...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.13717
更新日期：2019-03-01 00:00:00
abstract：:Lipoblastoma is a rare neoplasm of embryonal adipose tissue most often encountered on the trunk and extremities of children. It commonly presents as a painless subcutaneous soft tissue mass, but there are other unique clinical presentations that are important to recognize. The differential is broad and includes sarcom...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.13071
更新日期：2017-03-01 00:00:00
abstract：:Raynaud's phenomenon (RP) is a vasospastic disorder characterized by recurrent self-limited episodes of skin pallor, cyanosis, and hyperemia caused by paroxysmal spasms in the small arteries of the fingers and toes and can occur in any age group. Hands, feet, nose, ears, and nipples can be affected. The diagnosis is m...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.13129
更新日期：2017-05-01 00:00:00
abstract：:Discoid lupus erythematosus (DLE) is rare in childhood. We report the case of a 5-year-old girl who presented with erythematous scaly plaques, with scarring alopecia, involving approximately 40% of her scalp. Histopathology confirmed the diagnosis of DLE. Treatment with intravenous methylprednisolone, hydroxychloroqui...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.2009.00916.x
更新日期：2009-05-01 00:00:00
abstract：:Trisomy 13, or Patau syndrome, is a chromosomal disorder that can occur in complete, partial, or mosaic forms. Mosaicism is observed in 6% of individuals with trisomy 13 and, in contrast to the complete form, has wide phenotypic variability, longer survival, and in some patients an unusual skin pigmentary pattern simi...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.12339
更新日期：2014-09-01 00:00:00
abstract：:Granulomatous mycosis fungoides (GMF) is a rare form of mycosis fungoides (MF) characterized by an infiltrate of atypical lymphocytes, histiocytes, and multinucleated giant cells. Clinically, GMF has a slowly progressing course with a worse prognosis than other forms of MF. With its peak incidence being in the fifth t...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.12959
更新日期：2016-09-01 00:00:00
abstract：:Isolated benign primary cutaneous plasmacytosis in a child is a very rare and benign disease. Herein we present a case of this condition occurring in a child who showed good response to topical corticosteroid. ...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.12449
更新日期：2014-11-01 00:00:00
abstract：:Polyurethane chemicals are produced by the reaction of isocyanates and they may cause allergic contact dermatitis or precipitate asthma attacks. Contact dermatitis to polyurethane toilet seat has not been reported before. Herein we present a case of allergic contact dermatitis to polyurethane toilet seat. ...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.2011.01482.x
更新日期：2011-11-01 00:00:00
abstract：:Triethanolamine is used as an emulsifier in many cosmetics and in topical medications, yet the occurrence of contact dermatitis to cosmetics containing triethanolamine is rare in childhood. Our case highlights how young age should not be a deterrent to investigation and demonstrates the importance of patch testing wit...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.12537
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Bullous impetigo (BI) is a common skin infection of early childhood, resulting from desmoglein-1 cleavage by Staphylococcus aureus exfoliative toxins. Due to compromised barrier function and immune dysregulation, children with atopic dermatitis (AD) are at increased risk of cutaneous infections, yet no liter...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.14032
更新日期：2020-01-01 00:00:00
abstract：:Aplasia cutis congenita (ACC) is characterized by the complete or partial absence of skin at birth, with 85% of cases of ACC involving the scalp vertex. The etiology of ACC is unclear and appears to be multifactorial. We present the case of a 3-month-old boy who presented with a diagnosis of non-scalp ACC affecting ap...
journal_title：Pediatric dermatology
pub_type：
doi：10.1111/pde.14528
更新日期：2021-01-22 00:00:00
abstract：:Knowledge of the molecular underpinnings of many epidermal nevi and epidermal nevus syndrome has expanded rapidly in recent years. In this review and update on epidermal nevus syndrome, we will cover recent genetic discoveries involving epidermal nevi, including nevus sebaceus, keratinocytic epidermal nevus, nevus com...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.13273
更新日期：2018-01-01 00:00:00
abstract：:Infantile hemangiomas are the most common benign vascular tumors in childhood. Propranolol is the first-line treatment for infantile hemangiomas, but failures may occur. Sirolimus, an mTOR inhibitor, is a promising drug for the treatment of vascular malformations and vascular tumors. We present the case of a child wit...
journal_title：Pediatric dermatology
pub_type：
doi：10.1111/pde.14163
更新日期：2020-07-01 00:00:00
abstract：:In addition to the evaluation of melanocytic growths (Part I), dermoscopy is helpful in the identification and management of vascular tumors, skin infections, and inflammatory conditions. In this practical review, we present the classic dermoscopic findings of the following: vascular tumors, infectious conditions (mol...
journal_title：Pediatric dermatology
pub_type： 杂志文章,评审
doi：10.1111/pde.14284
更新日期：2020-09-01 00:00:00
abstract：:Infantile acne is a rare occurrence. It is more common in boys and predominately occurs on the cheeks in infants between the ages of 1 and 16 months. Clinically, the lesions range from comedones to inflammatory papulopustules to cysts. Successful therapies include topical tretinoin, benzoyl peroxide and topical and or...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.2005.22224.x
更新日期：2005-03-01 00:00:00
abstract：:Although lentigines are usually benign, they can be associated with a number of genetic syndromes in which neoplasms and other multi-system pathological processes occur. Here, we report the case of a 6-year-old girl who presented with atypical lentiginosis and hyperpigmentation caused by a de novo genetic variant in t...
journal_title：Pediatric dermatology
pub_type：
doi：10.1111/pde.13952
更新日期：2019-11-01 00:00:00
abstract：:Childhood lichen sclerosus (LS) is a rare and often misdiagnosed inflammatory dermatitis with an unpredictable course. The complications of LS are architectural changes of the vulva; malignant transformation is possible. The objective of our study was to define the background and the long-term course of childhood LS. ...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.12109
更新日期：2013-07-01 00:00:00
abstract：:Fibroadipose vascular anomaly (FAVA) is a rare, complex mesenchymal malformation combining fibrofatty replacement of the affected muscles and slow-flow vascular malformation. The condition is characterized by localized swelling, severe pain, phlebectasia, and contracture of the affected limb. Treatment paradigms are n...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.13260
更新日期：2017-11-01 00:00:00
abstract：:Kwashiorkor is a common affliction of children worldwide. It occurs less often in developed countries, but has been reported under a variety of circumstances, including poverty, neurologic disease, and malabsorption. Because of its rare occurrence in the United States and because the affected child has an edematous ra...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1046/j.1525-1470.1999.00023.x
更新日期：1999-03-01 00:00:00
abstract：:We report a 10-month-old boy who presented with a giant perianal condyloma acuminatum, and a similar lesion on the neck. These lesions were treated by surgical excision with satisfactory results. This size, extent, and early age of appearance make this case highly unusual. ...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/j.1525-1470.2009.00968.x
更新日期：2009-07-01 00:00:00
abstract：:We describe deep granuloma annulare (DGA) of the forehead mimicking inflamed cysts. Reactive inflammation and sterile purulent drainage may be an underrecognized feature of DGA. ...
journal_title：Pediatric dermatology
pub_type： 杂志文章
doi：10.1111/pde.13137
更新日期：2017-07-01 00:00:00
