Smooth muscle cell signal transduction: implications of vascular biology for vascular surgeons.

Abstract:

:Vascular smooth muscle cells exhibit varied responses after vessel injury and surgical interventions, including phenotypic switching, migration, proliferation, protein synthesis, and apoptosis. Although the source of the smooth muscle cells that accumulate in the vascular wall is controversial, possibly reflecting migration from the adventitia, from the circulating blood, or in situ differentiation, the intracellular signal transduction pathways that control these processes are being defined. Some of these pathways include the Ras-mitogen-activated protein kinase, phosphatidylinositol 3-kinase-Akt, Rho, death receptor-caspase, and nitric oxide pathways. Signal transduction pathways provide amplification, redundancy, and control points within the cell and culminate in biologic responses. We review some of the signaling pathways activated within smooth muscle cells that contribute to smooth muscle cell heterogeneity and development of pathology such as restenosis and neointimal hyperplasia.

journal_name

J Vasc Surg

authors

Muto A,Fitzgerald TN,Pimiento JM,Maloney SP,Teso D,Paszkowiak JJ,Westvik TS,Kudo FA,Nishibe T,Dardik A

doi

10.1016/j.jvs.2007.02.061

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

A15-24

eissn

0741-5214

issn

1097-6809

pii

S0741-5214(07)00353-9

journal_volume

45 Suppl A

pub_type

杂志文章,评审
  • Improved operative exposure of infrapopliteal vessels in combined vascular and orthopedic injuries.

    abstract::In a series of six patients, a single-bar anterior external fixator was used to treat combined vascular and orthopedic injuries of the leg. This method of external fixation facilitated operative vascular exposure without sacrificing bony stability or alignment. It may be the preferred method of external fixation for t...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:

    authors: Dreyfuss DC,Kaufman JL,Flancbaum L,Stark KR,Dinerstein CR

    更新日期:1987-10-01 00:00:00

  • Inadequacy of saphenous vein grafts for cross-femoral venous bypass.

    abstract::A mathematic model of unilateral iliac vein obstruction was used to establish the theoretic basis for selecting saphenous vein or a larger diameter prosthetic cross-femoral venous bypass graft for relief of obstructive venous hypertension. Common femoral vein resting and postexercise peak flows, and common femoral vei...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:

    authors: Lalka SG,Lash JM,Unthank JL,Lalka VK,Cikrit DF,Sawchuk AP,Dalsing MC

    更新日期:1991-05-01 00:00:00

  • Early control of the distal internal carotid artery during endarterectomy: achievability and results.

    abstract:PURPOSE:The purpose of this study was the report of the results of a consecutive series of carotid endarterectomy (CEA), performed by one surgeon and independently assessed by a neurologist, in which the achievability of selective early control of the distal internal carotid artery (ICA) was prospectively recorded. ME...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1067/mva.2002.122028

    authors: Bourke BM,Crimmins DS

    更新日期:2002-07-01 00:00:00

  • Cystic adventitial disease of the femoral vein presenting as deep vein thrombosis: a case report and review of the literature.

    abstract::Cystic adventitial disease of veins is a rare condition. We report the case of a 28-year-old man who presented with a swollen leg secondary to obstruction of the common femoral vein as a result of this disease. He underwent excision of the cyst and made a full recovery. The presentation, investigation, treatment and p...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2006.05.034

    authors: Dix FP,McDonald M,Obomighie J,Chalmers N,Thompson D,Benbow EW,Smyth JV

    更新日期:2006-10-01 00:00:00

  • Dose-dependent neuroprotection of delta-opioid peptide [D-Ala(2), D-Leu(5)] enkephalin on spinal cord ischemia-reperfusion injury by regional perfusion into the abdominal aorta in rabbits.

    abstract:OBJECTIVE:In our prior study, we showed that delta-opioid peptide [D-Ala(2), D-Leu(5)] enkephalin (DADLE), by regional perfusion into the abdominal aorta, could protect the spinal cord against ischemia-reperfusion (I/R) injury caused by aortic occlusion. However, the relative dose-response effects of DADLE still remain...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2014.11.074

    authors: Liu H,Chen B,Li S,Yao J

    更新日期:2016-04-01 00:00:00

  • Banding of the common iliac artery: an expedient in endoluminal correction of aortoiliac aneurysms.

    abstract::Dilatation of the common iliac arteries is one of the most frequent causes for exclusion of patients in a series of endovascular correction of abdominal aortic aneurysms (AAAs). In this article we describe the banding technique we use to constrict the large iliac arteries. Four patients underwent endovascular treatmen...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1067/mva.2000.109771

    authors: Puech-Leão P

    更新日期:2000-12-01 00:00:00

  • Steady and pulsatile flow fields in an end-to-side arterial anastomosis model.

    abstract::We investigated the flow field within a rigid-walled in vitro model of an end-to-side 45 degree anastomosis in an attempt to identify possible hemodynamic factors that may contribute to the pathogenesis of distal anastomotic intimal hyperplasia. A high-resolution photochromic tracer technique was used to visualize the...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1067/mva.1990.24365

    authors: Ojha M,Ethier CR,Johnston KW,Cobbold RS

    更新日期:1990-12-01 00:00:00

  • Therapeutic site selection is important for the successful development of collateral vessels.

    abstract:BACKGROUND:Induction of collateral development to improve tissue perfusion is a promising approach for the treatment of arterial occlusive diseases. Several growth factors and cells have been reported to increase collateral circulation; however, the appropriate site for the delivery of these factors and cells is unclea...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2014.02.004

    authors: Nishiyama A,Koyama H,Miyata T,Watanabe T

    更新日期:2015-07-01 00:00:00

  • A systematic review of the limitations and approaches to improve detection and management of peripheral arterial disease in Hispanics.

    abstract::Peripheral arterial disease (PAD) is a highly prevalent public health problem associated with major detrimental effects on quality of life and functional status, and it is also the main cause of limb amputation. More importantly, PAD has been classified as a coronary artery disease equivalent, meaning that patients wi...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.jvs.2009.08.085

    authors: Rosero EB,Kane K,Clagett GP,Timaran CH

    更新日期:2010-04-01 00:00:00

  • Prosthetic thigh arteriovenous access: outcome with SVS/AAVS reporting standards.

    abstract:PURPOSE:Differences in the reporting methods of results for arteriovenous (AV) access can dramatically affect apparent outcome. To enable meaningful comparisons in the literature, the Society for Vascular Surgery and the American Association for Vascular Surgery (SVS/AAVS) recently published reporting standards for dia...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/s0741-5214(03)00720-1

    authors: Cull JD,Cull DL,Taylor SM,Carsten CG 3rd,Snyder BA,Youkey JR,Langan EM 3rd,Blackhurst DW

    更新日期:2004-02-01 00:00:00

  • Contemporary comparison of aortofemoral bypass to alternative inflow procedures in the Veteran population.

    abstract:OBJECTIVE:Multiple vascular inflow reconstruction options exist for claudication, including aortofemoral bypass (AFB) and alternative inflow procedures (AIPs) such as femoral reconstruction with iliac stents, and femoral-femoral, iliofemoral, and axillofemoral bypass. Contemporary multi-institution comparison of these ...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2016.05.081

    authors: McPhee JT,Madenci A,Raffetto J,Martin M,Gupta N

    更新日期:2016-12-01 00:00:00

  • Endovascular treatment as first line approach for infrarenal aortic occlusive disease.

    abstract:INTRODUCTION:The purpose of this study was to report the early and late results of primary stenting for focal atherosclerotic lesions of the infrarenal aorta. METHODS:A retrospective analysis of 52 consecutive patients treated for infrarenal occlusive aortic disease with primary stenting between January 2002 and Novem...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2011.02.007

    authors: Schwindt AG,Panuccio G,Donas KP,Ferretto L,Austermann M,Torsello G

    更新日期:2011-06-01 00:00:00

  • Experience of temporary inferior vena cava filters inserted in the perinatal period to prevent pulmonary embolism in pregnant women with deep vein thrombosis.

    abstract:OBJECTIVE:We placed temporary inferior vena cava filters to prevent pulmonary thromboembolism in patients with deep vein thrombosis (DVT) who were presumed to have an increased risk of pulmonary embolism in the perinatal period. These experiences of using temporary inferior vena cava filters in pregnant women are repor...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2005.01.023

    authors: Kawamata K,Chiba Y,Tanaka R,Higashi M,Nishigami K

    更新日期:2005-04-01 00:00:00

  • Open repair of thoracoabdominal aortic aneurysms in experienced centers.

    abstract:OBJECTIVE:We performed a systematic review and meta-analysis aiming to assess the mortality and morbidity of all published case series on thoracoabdominal aortic aneurysms (TAAAs) in experienced centers treated with open repair. METHODS:A systematic search of the literature published until April 2017 was performed acc...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jvs.2018.03.410

    authors: Moulakakis KG,Karaolanis G,Antonopoulos CN,Kakisis J,Klonaris C,Preventza O,Coselli JS,Geroulakos G

    更新日期:2018-08-01 00:00:00

  • The effect of cigarette smoke, nicotine, and carbon monoxide on the permeability of the arterial wall.

    abstract::The association between cigarette smoking and the development of atherosclerosis is well established, but the mechanism that makes cigarettes such a potent "risk factor" is not understood. There is normally a constant insudation of plasma macromolecules into the arterial wall. Fibrinogen and lipids are two of the larg...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:

    authors: Allen DR,Browse NL,Rutt DL,Butler L,Fletcher C

    更新日期:1988-01-01 00:00:00

  • Application of gelatin sponge sandwich as a hemostatic aid to percutaneous suture-mediated arteriotomy closure.

    abstract::Suture-mediated closure devices are increasingly used for closure of large arteriotomies, such as those required for endovascular aortic repair. One of the commonly encountered situations is persistent arteriotomy oozing after successful closure requiring manual compression. The purpose of this report is to describe a...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2012.09.022

    authors: Pua U

    更新日期:2013-02-01 00:00:00

  • A novel approach for hybrid repair of type B aortic dissection associated with coarctation of the aorta.

    abstract::We report the case of an acute type B aortic dissection in association with an unknown isthmic coarctation in a 53-year-old man. An intimal tear was located just distal to the coarctation, and the intimal flap extended to the level of the renal arteries. Hybrid repair was performed successfully 4 months later, without...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2013.05.089

    authors: Li Y,Fan Z,Huang L,Xue Y,Sun L

    更新日期:2014-05-01 00:00:00

  • Preservation of the accessory renal arteries after endovascular repair of common iliac artery aneurysm using kissing stent grafts.

    abstract::Exclusion of the accessory renal arteries (ARAs) is required during endovascular aneurysm repair if they arise from the sealing zone or aneurysm sac. Here, we report a case of successful endovascular treatment for a common iliac artery aneurysm located close to the aortic bifurcation and associated with nephrotic synd...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2014.05.042

    authors: Hosaka A,Miyata T,Nishiyama A,Miyahara T,Hoshina K,Shigematsu K

    更新日期:2016-02-01 00:00:00

  • Challenges of distal bypass surgery in patients with diabetes: patient selection, techniques, and outcomes.

    abstract::Surgical revascularization of the lower extremity using bypass grafts to distal target arteries is an established, effective therapy for advanced ischemia. Recent multicenter data confirm the primacy of autogenous vein bypass grafting, yet there remains significant heterogeneity in the utilization, techniques, and out...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.jvs.2010.06.015

    authors: Conte MS

    更新日期:2010-09-01 00:00:00

  • A surgeon's obligations when performing new procedures.

    abstract::A junior member of the vascular surgery faculty has done two robotic abdominal aneurysmectomies. Although he attended a standard 2-day training course conducted by the instrument manufacturer, performed several similar procedures in the animal laboratory, and read all the recent pertinent literature, technical errors ...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1067/mva.2002.121817

    authors: Jones JW,McCullough LB

    更新日期:2002-02-01 00:00:00

  • Variation and changes in state-specific carotid endarterectomy and 30-day mortality rates, United States, 1991-2000.

    abstract:OBJECTIVES:The objectives of this study were to investigate variations between states and changes in state-specific carotid endarterectomy (CEA) and 30-day mortality rates. Cross-sectional variations and changes over time in such measures may be indicative of improvement in the quality of care. METHODS:We performed re...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/s0741-5214(03)00616-5

    authors: Sheikh K,Bullock C

    更新日期:2003-10-01 00:00:00

  • The association between venous structural alterations and biomechanical weakness in patients with abdominal aortic aneurysms.

    abstract:OBJECTIVE:Abdominal aortic aneurysms (AAAs) are associated with generalized arterial dilation, torturosity, and altered matrix composition, which suggests a generalized systemic weakness throughout the entire vasculature. The aim of this study was to determine whether this phenomenon was present in the venous tissue of...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1067/mva.2002.122877

    authors: Goodall S,Crowther M,Bell PR,Thompson MM

    更新日期:2002-05-01 00:00:00

  • New experiences with absolute ethanol sclerotherapy in the management of a complex form of congenital venous malformation.

    abstract:BACKGROUND:Complex forms of congenital venous malformation have defied proper classification and confounded therapy. Through a newly designed multidisciplinary approach, these venous defects were properly diagnosed and classified according to the Hamburg classification. Absolute ethanol was adopted as a new scleroagent...

    journal_title:Journal of vascular surgery

    pub_type: 评论,杂志文章

    doi:10.1067/mva.2001.112209

    authors: Lee BB,Kim DI,Huh S,Kim HH,Choo IW,Byun HS,Do YS

    更新日期:2001-04-01 00:00:00

  • Endovascular brachytherapy for renal artery in-stent restenosis.

    abstract:OBJECTIVE:Renal artery in-stent restenosis (RAISR) is not an infrequent occurrence and may be in part responsible for the failure of renal stents to improve clinical outcome. A variety of treatments have been used to restore patency, with mixed results. These include repeated percutaneous transluminal renal angioplasty...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/j.jvs.2014.08.078

    authors: Silverman SH,Exline JB,Silverman LN,Samson RH

    更新日期:2014-12-01 00:00:00

  • Clinical and technical factors influencing recurrent carotid stenosis and occlusion after endarterectomy.

    abstract::Carotid endarterectomy was performed in 152 patients during a 27-month period. The first 82 patients had primary closure of the arteriotomy, whereas the subsequent 70 patients underwent closure with Dacron patch angioplasty. Duplex scanning was undertaken postoperatively in 102 of these patients with a mean follow-up ...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:

    authors: Ouriel K,Green RM

    更新日期:1987-05-01 00:00:00

  • Persistent platelet activation by passivated grafts.

    abstract::Vascular grafts in canines exhibit similar healing patterns to humans in that the graft surface forms a pseudointima over time but endothelializes only near the anastomotic sites. Thus the pseudointima at the midportion of the graft may represent a nidus for persistent platelet activation. The purpose of this investig...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:

    authors: Ito RK,Brophy CM,Contreras MA,Tsoukas A,LoGerfo FW

    更新日期:1991-06-01 00:00:00

  • Influence of multiple stents on periprocedural stroke after carotid artery stenting in the Carotid Revascularization Endarterectomy versus Stent Trial (CREST).

    abstract:BACKGROUND:In the Carotid Revascularization Endarterectomy versus Stent Trial (CREST), carotid artery atherosclerotic lesion length and nature of the lesions were important factors that predicted the observed difference in stroke rates between carotid endarterectomy and carotid artery stenting (CAS). Additional patient...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jvs.2018.06.221

    authors: Lal BK,Roubin GS,Jones M,Clark W,Mackey A,Hill MD,Voeks JH,Howard G,Hobson RW 2nd,Brott TG

    更新日期:2019-03-01 00:00:00

  • Elevations of tissue-type plasminogen activator and differential expression of urokinase-type plasminogen activator in diseased aorta.

    abstract:PURPOSE:Elevations of plasmin have been implicated in the pathogenesis of abdominal aortic aneurysms (AAA) because of its ability to digest extracellular matrix proteins. Plasminogen activators regulate the conversion of plasminogen to plasmin. Tissue-type plasminogen activator (tPA) is more important in modulation of ...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/s0741-5214(97)70333-1

    authors: Shireman PK,McCarthy WJ,Pearce WH,Shively VP,Cipollone M,Kwaan HC

    更新日期:1997-01-01 00:00:00

  • Femoropopliteal percutaneous transluminal angioplasty for limb salvage.

    abstract::The role of balloon catheter femoropopliteal percutaneous transluminal angioplasty (FP PTA) continues to be controversial 14 years after its initial description. In high-risk patients with limb-threatening ischemia, the role of FP PTA is unknown. We reviewed the cases of 27 patients in whom high operative risk and adv...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:

    authors: Milford MA,Weaver FA,Lundell CJ,Yellin AE

    更新日期:1988-09-01 00:00:00

  • Open surgical and endovascular treatment of superior vena cava syndrome caused by nonmalignant disease.

    abstract:OBJECTIVES:The purpose of this study was to evaluate the role of endovascular and open surgical reconstructions in patients with superior vena cava (SVC) syndrome caused by nonmalignant disease. METHODS:Clinical data from 32 consecutive patients who underwent endovascular or open surgical reconstruction of central vei...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章

    doi:10.1016/s0741-5214(03)00331-8

    authors: Kalra M,Gloviczki P,Andrews JC,Cherry KJ Jr,Bower TC,Panneton JM,Bjarnason H,Noel AA,Schleck C,Harmsen WS,Canton LG,Pairolero PC

    更新日期:2003-08-01 00:00:00