Septal and hippocampal release of vasopressin and oxytocin during late pregnancy and parturition in the rat.

abstract：:A reproductive facet of ghrelin, a stomach-derived orexigenic peptide involved in energy homeostasis, has been recently suggested, and predominantly inhibitory effects of ghrelin upon luteinizing hormone (LH) secretion have been demonstrated in rat models. Yet, the modulatory actions of ghrelin on the gonadotropic axi...

journal_title：Neuroendocrinology

authors： Fernández-Fernández R,Tena-Sempere M,Navarro VM,Barreiro ML,Castellano JM,Aguilar E,Pinilla L

更新日期：2005-01-01 00:00:00

abstract：:The ability of dopamine receptor antagonists to stimulate prolactin release in rats with medial basal hypothalamic lesions was investigated. Starting levels of prolactin were elevated to approximately 400 ng/ml in animals in which the tuberoinfundibular dopaminergic neurons were completely destroyed by the lesion. In ...

journal_title：Neuroendocrinology

authors： Cheung CY,Neill AC,Weiner RI

更新日期：1981-06-01 00:00:00

abstract：:The effects of (D-Met2,Pro5)-enkephalinamide--a superactive enkephalin analogue--on the preovulatory discharge of gonadotrophic hormones and on ovulation were investigated. Injection of the opioid (16 nmol) into a lateral cerebral ventricle of regularly cycling female rats immediately before the critical period on the...

journal_title：Neuroendocrinology

authors： Köves K,Marton J,Molnár J,Halász B

更新日期：1981-02-01 00:00:00

abstract：:Sexual differentiation of brain function is regulated by estrogen in the perinatal period of rodents. However, the role of the estrogen receptor subtypes ERα and ERβ is still in question. Accordingly, the effects of neonatal treatment with the ERα agonist propyl pyrazole triol (PPT) or the ERβ agonist diarylpropionitr...

journal_title：Neuroendocrinology

authors： Kanaya M,Yamanouchi K

更新日期：2012-01-01 00:00:00

abstract：:The role of endogenous opioid peptides in the control of gonadotropin-releasing hormone pulse generator activity was examined in long-term ovariectomized goats by recording the hypothalamic multiple-unit activity specifically associated with pulsatile luteinizing hormone secretion (MUA volleys). Administration of nalo...

journal_title：Neuroendocrinology

authors： Ito K,Tanaka T,Mori Y

更新日期：1993-04-01 00:00:00

abstract：:The anterior pituitary is permanently regulated by processes of apoptosis and proliferation in order to maintain tissue homeostasis. Several factors have been implicated in this regulation and lately, prolactin (PRL) has been included into that list. However, since PRL is secreted by anterior pituitary lactotropes, th...

journal_title：Neuroendocrinology

authors： Ferraris J,Bernichtein S,Pisera D,Goffin V

更新日期：2013-01-01 00:00:00

abstract：:Vasopressin-containing neurosecretory cells are partly regulated by GABAergic neurons present both at the hypothalamic and the pituitary level. In the present work, we compared GABA effects on vasopressin release from posterior pituitaries of Sprague-Dawley (SPD), Wistar (W), Wistar-Kyoto (WKY) and spontaneously hyper...

journal_title：Neuroendocrinology

authors： Magnusson AM,Meyerson BJ

更新日期：1993-11-01 00:00:00

abstract：:Specific lesions of different brain structures known to contain or to be coursed by LHRH neurons have been carried out in intact cycling female rats in order to investigate the role played by central LHRH and neuronal systems in the regulation of ovarian and hypophyseal LHRH receptor (LHRH-R) levels, using the stable ...

journal_title：Neuroendocrinology

authors： Marchetti B,Cioni M,Scapagnini U

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND/AIMS:Plasma chromogranin A (CgA) is the most widely used biochemical biomarker in the diagnostic workup and follow-up of gastroenteropancreatic neuroendo- crine neoplasms (GEP-NENs). Herein, we assessed the clinical utility of CgA in diagnosing and monitoring a large series of GEP-NENs. PATIENTS AND METHODS...

journal_title：Neuroendocrinology

authors： Massironi S,Rossi RE,Casazza G,Conte D,Ciafardini C,Galeazzi M,Peracchi M

更新日期：2014-01-01 00:00:00

abstract：:alpha-Methyl-p-tyrosine (alpha-MT), a competitive inhibitor of tyrosine hydroxylase, was used to block the synthesis of hypothalamic catecholamines in immature female rats of 14, 16 and 30 days of age and in castrated adults. The administration of alpha-MT (300 mg/kg body weight, free base) induced a significant decay...

journal_title：Neuroendocrinology

authors： Moguilevsky JA,Arias P,Szwarcfarb B,Carbone S,Rondina D

更新日期：1990-10-01 00:00:00

abstract：:Molecules of astrocyte origin influence gonadotropin-releasing hormone (GnRH) release and GnRH neuronal growth and differentiation. Furthermore, type 1 astrocytes express steroid receptors, presenting the possibility that steroid actions on GnRH neurons might occur via astrocytes. Utilizing GT1-7 cells, a GnRH-secreti...

journal_title：Neuroendocrinology

authors： Zwain IH,Arroyo A,Amato P,Yen SS

更新日期：2002-06-01 00:00:00

abstract：:Estrogens are crucial determinants in the regulation of anterior pituitary function and maintenance of tissue homeostasis. Estrogen actions in this gland are exerted through both classical and non-classical mechanisms of action. This review summarizes the expression of classical α- and β-estrogen receptors and variant...

journal_title：Neuroendocrinology

authors： Zárate S,Seilicovich A

更新日期：2010-01-01 00:00:00

abstract：:Studies were performed to determine the role of thyroid hormone in the suppression of thyrotropin (TSH) by opiates. Serum samples were collected by decapitation 1, 3, 6, 12, 24, or 48 h after rats were implanted with 1 sustained-release morphine (75 mg) or placebo pellet. Morphine decreased TSH by 44% at 1 h and by 83...

journal_title：Neuroendocrinology

authors： Berglund LA,Millard WJ,Gabriel SM,Simpkins JW

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The outcomes of bariatric surgery are very irregular and mostly unpredictable. The search for variables of predictive value is encouraged to help preventing therapeutic failures. OBJECTIVE:We aimed to confirm the hypothesis that preexisting eating behaviors could predict neuroendocrine and metabolic outcome...

journal_title：Neuroendocrinology

authors： Muñoz-Rodríguez JR,Rodríguez-Cano T,Polo F,Sáenz-Mateos L,Agarrado A,Segura E,Casas G,Martín-Fernández J,Beato-Fernández L,Salas E,González-Martín C,Alguacil LF

更新日期：2020-01-01 00:00:00

abstract：:The present study investigated the effects of short-term exposure to constant light, initiated at the time of ovariectomy, on the ability of estradiol (E2) treatment alone or in conjunction with progesterone (P) to induce afternoon surges of LH and prolactin (PRL). Adult Fischer 344 rats, which had been ovariectomized...

journal_title：Neuroendocrinology

authors： Sterner MR,Cohen IR

更新日期：1995-09-01 00:00:00

abstract：:The studies reported in this paper were undertaken to investigate the effect of chronic (10 day) alcohol consumption on female pituitary-gonadal function. The immature female rat model treated with pregnant mare serum gonadotropin (PMSG) was used since it results in a highly reproducible luteinizing hormone (LH) surge...

journal_title：Neuroendocrinology

authors： Sundberg DK,Bo WJ,Reilly J

更新日期：1987-10-01 00:00:00

abstract：:Previous studies indicate that 7 days after testicular administration of naloxone, serum testosterone (T) concentration and basal T secretion in vitro decrease significantly. In neonatal rats, short-term (2 h) intratesticular treatment with 0.3 micrograms (D-Met2-Pro5)-enkephalinamide suppresses steroidogenesis. In th...

journal_title：Neuroendocrinology

authors： Gerendai I,Nemeskéri A,Csernus V

更新日期：1992-09-01 00:00:00

abstract：:Neuronal nitric oxide synthase, e.g. NADPH diaphorase (NADPH-d), catalyzes formation of the free radical, nitric oxide (NO), and occurs within brain structures that have functional significance for energy fuel homeostasis. The following studies examined whether populations of NADPH-d-positive neurons in the hypothalam...

journal_title：Neuroendocrinology

authors： Briski KP,Sylvester PW

更新日期：1999-03-01 00:00:00

abstract：:The effect of long-term decreases in circulating concentrations of prolactin was determined on the responsiveness of tuberoinfundibular dopamine (DA) neurons to this hormone. The activity of these neurons in ovariectomized rats was estimated by measuring the rate of DA synthesis (DOPA accumulation after the administra...

journal_title：Neuroendocrinology

authors： Demarest KT,Riegle GD,Moore KE

更新日期：1985-05-01 00:00:00

abstract：:Acetylcholinesterase (AChE) activity, and concentrations of monoamines, monoamine metabolites and oxytocin (OT) were measured in the cerebrospinal fluid (CSF) of sheep during late pregnancy, labour, parturition, vaginocervical stimulation, lamb separation and suckling. Concentrations of AChE, 4-hydroxy-3 methoxyphenyl...

journal_title：Neuroendocrinology

authors： Kendrick KM,Keverne EB,Baldwin BA,Sharman DF

更新日期：1986-01-01 00:00:00

abstract：:The pressor effect of intravenous angiotensin II (AII) was compared in the unrestrained rat before and after electrolytic lesions of the subfornical organ (SFO), the circumventricular organ of the dorsal third cerebral ventricle. Abdominal aortic and venal caval catheters were used to measure arterial pressure and to ...

journal_title：Neuroendocrinology

authors： Mangiapane ML,Simpson JB

更新日期：1980-12-01 00:00:00

abstract：:Previous work has demonstrated that physiological concentrations of 17beta-estradiol can protect the female rat brain against middle cerebral artery occlusion (MCAO)-induced ischemic damage. The present study examined whether therapeutic doses of the clinically relevant selective estrogen receptor modulator (SERM), ta...

journal_title：Neuroendocrinology

authors： Mehta SH,Dhandapani KM,De Sevilla LM,Webb RC,Mahesh VB,Brann DW

更新日期：2003-01-01 00:00:00

abstract：:In previous studies we obtained evidence that serotonin release by p-chloroamphetamine (PCA) causes an increase in corticosterone secretion but that this effect is not mediated via the raphe nuclei in the midbrain. In contrast, PCA-induced prolactin secretion was abolished by dorsal raphe lesions. In the present study...

journal_title：Neuroendocrinology

authors： Van de Kar LD,Karteszi M,Bethea CL,Ganong WF

更新日期：1985-11-01 00:00:00

abstract：:In vivo and in vitro methods have been used to compare the effects of opioid receptor blockade on the functional activity of the hypothalamo-pituitary-gonadal axis in adult (200 g) and sexually immature (50 g) male rats. In the adult, a single injection of the mu-receptor antagonist, naloxone (500 micrograms/100 g bod...

journal_title：Neuroendocrinology

authors： Leposavic G,Cover PO,Buckingham JC

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND/AIM:The mode of action of the somatostatin analog octreotide on neuro-endocrine tumour proliferation is largely unknown. Overexpression of the proto-oncogene Akt/PKB (protein kinase B) has been demonstrated in certain neuro-endocrine tumours: Akt activates downstream proteins including mTOR and p70S6K, which...

journal_title：Neuroendocrinology

authors： Grozinsky-Glasberg S,Franchi G,Teng M,Leontiou CA,Ribeiro de Oliveira A Jr,Dalino P,Salahuddin N,Korbonits M,Grossman AB

更新日期：2008-01-01 00:00:00

abstract：:The mechanisms by which leptin influences energy homeostasis are not entirely understood. Several observations indicate that proopiomelanocortin (POMC) is involved in the regulation of food intake and may be a mediator of leptin action. To further study this interaction, a sensitive solution hybridization assay was us...

journal_title：Neuroendocrinology

authors： Korner J,Chua SC Jr,Williams JA,Leibel RL,Wardlaw SL

更新日期：1999-12-01 00:00:00

abstract：:The role of endogenous corticoids in fever responses caused by recombinant murine interleukin (IL)-1 beta and IL-6 was studied in adult male Wistar rats. Adrenalectomy diminished the development of fever after intracerebroventricular (icv) injection of these ILs and lowered body temperature. Intraperitoneal administra...

journal_title：Neuroendocrinology

authors： Schöbitz B,Holsboer F,Sutanto W,Gross G,Schönbaum E,de Kloet ER

更新日期：1994-04-01 00:00:00

abstract：:Previous studies have shown that the hypothalamic concentration of pro-opiomelanocortin (POMC) mRNA and several POMC-derived peptides increases in the rat 4 weeks after orchiectomy and that this increase can be prevented by testosterone replacement. In this study, we have examined the short-term effects of orchiectomy...

journal_title：Neuroendocrinology

authors： Wardlaw SL,Blum M

更新日期：1990-11-01 00:00:00

abstract：:Immunoreactive thyroid-stimulating hormone (IR-TSH) has been detected in the hypothalamus and is released in vitro by a calcium-dependent mechanism when the tissue is depolarized. Recently, immunocytochemical studies have revealed that IR-TSH is present in thyrotropes in the pars tuberalis. Therefore, because these th...

journal_title：Neuroendocrinology

authors： De Vito WJ,Connors JM,Hedge GA

更新日期：1985-07-01 00:00:00

abstract：:Previous work in many laboratories has shown that luteinizing hormone-releasing hormone (LHRH) neurons display a range of shapes from smooth-contoured to extremely irregular or 'thorny'. To determine if these forms reflect or can be modified by the gonadal steroid milieu, the morphology of LHRH neurons was examined in...

journal_title：Neuroendocrinology

authors： Witkin JW

更新日期：1989-04-01 00:00:00