Abstract:
:An interstitial deletion of the short arm of a chromosome 11 was found in Wilms' tumor cells of a patient without aniridia. The chromosomes in her peripheral blood lymphocytes were normal. The karyotype of the tumor cells is similar to that reported for the somatic cells of patients with aniridia-Wilms' tumor association. We showed that the same cytogenetic change as that seen in patients with this condition, namely, an interstitial deletion of 11p13, can occur in patients without aniridia as a mutation that is confined to tumor cells.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Kaneko Y,Egues MC,Rowley JDsubject
Has Abstractpub_date
1981-11-01 00:00:00pages
4577-8issue
11 Pt 1eissn
0008-5472issn
1538-7445journal_volume
41pub_type
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