Mesenchymal tumor hypoglycemia: the effect of a tumor tissue extract on the insulin and glucagon secretion from the isolated perfused porcine pancreas.

Abstract:

:Severe fasting hypoglycemia and hypoinsulinemia occurred in a sixty-six year old woman with an intrahepatic mesenchymal tumor. An extract from the tumor was potent in inhibiting the arginine-induced glucagon secretion from the isolated perfused porcine pancreas. This observation supports the theory recently advanced that mesenchymal tumor hypoglycemia in some cases is due to a still unknown factor secreted from the tumor, which directly inhibits pancreatic glucagon secretion.

journal_name

Am J Surg

authors

Jensen SL,Kühl C,Lauritsen KB,Moody AJ

doi

10.1016/0002-9610(78)90095-8

subject

Has Abstract

pub_date

1978-02-01 00:00:00

pages

192-5

issue

2

eissn

0002-9610

issn

1879-1883

pii

0002-9610(78)90095-8

journal_volume

135

pub_type

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