Enhanced tumor control following sequential treatments of photodynamic therapy (PDT) and localized microwave hyperthermia in vivo.

abstract：BACKGROUND AND OBJECTIVES:Nanotechnology may increase the speed of penetration into the skin. This study evaluated the efficacy, safety, and pharmacokinetics of a novel topical anesthetic nanocapsule formulation (2 g) containing 2.5% lidocaine and 2.5% prilocaine (nanorap-test formulation) compared to placebo (control ...

journal_title：Lasers in surgery and medicine

authors： Gobbato C,Gobbato A,Magalhães TB,Mendes GD,Ilha JO,Moreno RA,Antunes NJ,De Nucci G

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the potentials of a 1310-nm optical coherence tomography (OCT) system to penetrate the highly backscattering sclera in enucleated human eyes and provide visualization of intraocular structures by transscleral imaging. STUDY DESIGN/MATERIALS AND METHODS:OCT-images were generated by ...

journal_title：Lasers in surgery and medicine

authors： Hoerauf H,Winkler J,Scholz C,Wirbelauer C,Gordes RS,Koch P,Engelhardt R,Laqua H,Birngruber R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The conventional pulsed-dye laser (wavelength 585 nm, pulse duration 0.5 milliseconds) is seen as the standard treatment for port wine stains (PWS). Using the pulsed-dye laser at wavelengths of 590, 595, and 600 nm and at varying pulse durations of 1.5-40 milliseconds is one of the newest deve...

journal_title：Lasers in surgery and medicine

authors： Greve B,Raulin C

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Acute radiodermatitis (RD) is a distressing and painful skin reaction that occurs in 95% of the patients undergoing radiotherapy (RT). The aim of this study was to evaluate the effectiveness of photobiomodulation therapy (PBMT) in the prevention of acute RD in breast cancer (BC) patients undergoing RT. METHO...

journal_title：Lasers in surgery and medicine

authors： Robijns J,Censabella S,Claes S,Pannekoeke L,Bussé L,Colson D,Kaminski I,Bulens P,Maes A,Noé L,Brosens M,Timmermans A,Lambrichts I,Somers V,Mebis J

更新日期：2018-02-10 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Primary blast injury is produced by shock waves. Blast injuries to lungs are extremely critical threats to survival, but their etiology is largely undefined. The majority of animal models for these injuries use explosive or complex experimental settings, limiting the laboratory study of blast ...

journal_title：Lasers in surgery and medicine

authors： Satoh Y,Sato S,Saitoh D,Tokuno S,Hatano B,Shimokawaji T,Kobayashi H,Takishima K

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Low-level laser therapy (LLLT) is a noninvasive treatment for a wide-assortment of medical ailments. A recent application is for noninvasive body slimming. A Level 1 clinical study was completed and recorded a significant reduction in circumferential measurements across waist, hips, and thighs compared to pl...

journal_title：Lasers in surgery and medicine

authors： Jackson RF,Stern FA,Neira R,Ortiz-Neira CL,Maloney J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Kenalog application onto surgical wounds has been used to control dynamic pain following Laser-Assisted-Uvulo-Palatoplasty (LAUP) with good results in our department. When the effect was sub-optimal, insufficient ointment over the superior-lateral corner of wounds were always noted. Fulfilling...

journal_title：Lasers in surgery and medicine

authors： Li LP,Lee SS,Chuang AY,Niddam DM,Tung TH,Chen JK

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Erbium lasers are potential tools to remove caries and dental hard tissue but bond strengths of composites to those preparations are reported to be lower than conventional methods. The purpose of this study was to evaluate the effect of mechanical excavation and/or chemical alteration on bond s...

journal_title：Lasers in surgery and medicine

authors： Obeidi A,McCracken MS,Liu PR,Litaker MS,Beck P,Rahemtulla F

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The goal of this study was to use an inexpensive macroscopic imaging system to monitor tumor progression in mouse models in real-time with minimal intervention. STUDY DESIGN/MATERIALS AND METHODS:Illumination is provided via a xenon arc lamp and a fiber optic probe which delivers white light o...

journal_title：Lasers in surgery and medicine

authors： Carlson AL,Hoffmeyer MR,Wall KM,Baugher PJ,Richards-Kortum R,Dharmawardhane SF

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:As a potential therapy for malignant glioma, we tested the phthalocyanine photosensitizer Pc 4 for: (1) rapid clearance from the vasculature, (2) specificity for glioma, and (3) tumoricidal photosensitizing capability. STUDY DESIGN/MATERIALS AND METHODS:Parenchymal injection of U87 cells into...

journal_title：Lasers in surgery and medicine

authors： George JE 3rd,Ahmad Y,Varghai D,Li X,Berlin J,Jackowe D,Jungermann M,Wolfe MS,Lilge L,Totonchi A,Morris RL,Peterson A,Lust WD,Kenney ME,Hoppel CL,Sun J,Oleinick NL,Dean D

更新日期：2005-06-01 00:00:00

abstract：:partial ciliary processes argon laser photocoagulation (PCLP) in the management of glaucoma has been the subject of a carefully conducted, prospective 5+-year clinical trial in 22 eyes of 20 patients. The mean intraocular pressure (IOP) +/- SD was significantly lower (15.5 +/- 3.6 mm Hg) than before the procedure (29....

journal_title：Lasers in surgery and medicine

authors： Lee PF,Shihab Z,Eberle M

更新日期：1980-01-01 00:00:00

abstract：:This article reviews the principle uses of ophthalmic lasers, providing historical background with an emphasis on new applications and areas of investigation. Ophthalmic photocoagulation was the first medical laser application and has restored or maintained vision in millions of people. More recently, photodisruption ...

journal_title：Lasers in surgery and medicine

authors： Krauss JM,Puliafito CA

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Some oral bacteria are susceptible to killing by red light after their sensitization with toluidine blue O (TBO). The photochemotherapy of periodontal disease in vivo would require a therapeutic window where bacteria could be killed without adjacent normal tissue damage. STUDY DESIGN/MATERIALS...

journal_title：Lasers in surgery and medicine

authors： Soukos NS,Wilson M,Burns T,Speight PM

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Optical energy-based devices, including intense pulsed light (IPL) and potassium titanyl phosphate (KTP) lasers achieve reduction of pigmented and vascular lesions in a relatively similar number of treatments. This study aimed to evaluate the efficacy and safety of an IPL with a "KTP-like" filter emitting a ...

journal_title：Lasers in surgery and medicine

authors： Friedmann DP,Peterson JD

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Holmium laser lithotripsy is the gold standard for intracorporeal fragmentation of urinary calculi. Usually, a visible beam is superimposed on the IR treatment laser as an aiming beam to guide the surgeon. In vitro tests showed that this aiming beam (532 nm, power <1 mW) excites strong fluores...

journal_title：Lasers in surgery and medicine

authors： Lange B,Jocham D,Brinkmann R,Cordes J

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Herein an overview is provided of the causes, consequences, and significance of photodynamic therapy (PDT)-mediated effects on tumor oxygenation and blood flow during illumination. STUDY DESIGN/MATERIALS AND METHODS:Techniques particularly valuable to this research have included tissue oxygen ...

journal_title：Lasers in surgery and medicine

authors： Busch TM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Moraxella catarrhalis is a significant cause of pediatric otitis media (OM), which is the most prevalent bacterial infection in children and primary reason for antibiotic administration in this population. Moreover, biofilm formation has been implicated as a primary mechanism of chronic or recu...

journal_title：Lasers in surgery and medicine

authors： Luke-Marshall NR,Mang TS,Hansen LA,Campagnari AA

更新日期：2014-11-01 00:00:00

abstract：INTRODUCTION:Leg telangiectasias have been reported to have been treated with a variety of lasers. This study was designed to measure response to treatment of leg telangiectasias with a unique coupled 585 nm and 1064 nm pulse. METHODS:Sixty female patients (24-62 y.o., skin types II-IV) with leg vein varicosities were...

journal_title：Lasers in surgery and medicine

authors： Trelles MA,Weiss R,Moreno-Moragas J,Romero C,Vélez M,Alvarez X

更新日期：2010-11-01 00:00:00

abstract：:The use of pulsed laser radiation to recanalize occluded biliary endoprostheses was examined. In vitro measurements demonstrated that a repetitively pulsed organic dye laser transmitted through a small diameter quartz fiber can recanalize an occluded stent in less than 10 sec without causing visible damage to the sten...

journal_title：Lasers in surgery and medicine

authors： Nishioka NS,Kelsey PB,Kibbi AG,Mihm MC Jr,Anderson RR

更新日期：1987-01-01 00:00:00

abstract：:A modified excimer laser energy delivery system was used to irradiate 100 segments of normal and fibrous aorta in vitro. The laser beam was scanned into 8 fiber bundles consisting of 50 fibers each resulting in a reduction of the applied pulse energy. The total repetition rate was increased to 150 Hz in order to keep ...

journal_title：Lasers in surgery and medicine

authors： Xie DY,Hassenstein S,Oberhoff M,Hanke H,Baumbach A,Hohla K,Haase KK,Karsch KR

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cryogen spray cooling (CSC) has become an integral part of dermatologic laser surgery because of its ability to remove selectively large amounts of heat from human skin in short periods of time, thereby protecting the epidermis from unintended thermal injury. The objective of the present study...

journal_title：Lasers in surgery and medicine

authors： Franco W,Liu J,Romero-Méndez R,Jia W,Nelson JS,Aguilar G

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:This study aimed to determine the feasibility of conducting a full scale randomized controlled trial investigating the effectiveness of low level laser therapy (LLLT), also known as photobiomodulation (PBM) therapy, used in addition to conventional therapy, for managing breast cancer related lymphedema (BCRL...

journal_title：Lasers in surgery and medicine

authors： Baxter GD,Liu L,Tumilty S,Petrich S,Chapple C,Anders JJ,Laser Lymphedema Trial Team.

更新日期：2018-09-01 00:00:00

abstract：:We examined the biostimulating effects of helium-neon laser radiation (HeNe; 632.8 nm), pulsed infrared laser radiation (IR; 904 nm), and the two combined on skin wound healing in New Zealand white rabbits. Seventy-two rabbits received either 1) no exposure, 2) 1.65 J/cm2 HeNe, 3) 8.25 J/cm2 pulsed IR, or 4) both HeNe...

journal_title：Lasers in surgery and medicine

authors： Braverman B,McCarthy RJ,Ivankovich AD,Forde DE,Overfield M,Bapna MS

更新日期：1989-01-01 00:00:00

abstract：:Histological investigation of the dog's myocardium performed 7 and 25 days after irradiation with different doses of Nd-YAG laser show that the damage zone has the shape of a hollow sphere with minor changes in cardiomyocytes in the central part of the sphere. The small blood vessels in the irradiated zone remained un...

journal_title：Lasers in surgery and medicine

authors： Obelienius V,Knepa A,Lubite Y,Ambartzumian R,Isakov V,Koshelev E,Markin E

更新日期：1985-01-01 00:00:00

abstract：:We used a Q-switched Nd:YAG laser with non-linear optical crystals to produce the 5th (213 nm) and the 4th (266 nm) harmonic frequencies. Using these two wavelengths, we ablated fresh porcine corneas and type I collagen synthetic epikeratoplasty lenticules. For the 213-nm ablation, radiant exposure was 1.3 J/cm2. The ...

journal_title：Lasers in surgery and medicine

authors： Gailitis RP,Ren QS,Thompson KP,Lin JT,Waring GO 3rd

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Soft tissue sarcomas (STS) are a rare and heterogeneous group of malignant tumors that are often treated through surgical resection. Current intraoperative margin assessment methods are limited and highlight the need for an improved approach with respect to time and specificity. Here we investi...

journal_title：Lasers in surgery and medicine

authors： Nguyen JQ,Gowani ZS,O'Connor M,Pence IJ,Nguyen TQ,Holt GE,Schwartz HS,Halpern JL,Mahadevan-Jansen A

更新日期：2016-10-01 00:00:00

abstract：:During a ten-year period 642 abdominal hollow organ resections have been performed by means of a new, original technique--that is, CO2 laser irradiation combined with specially designed instrumentation. This resulted in a remarkable decrease in postoperative morbidity and mortality. The article describes the laser pro...

journal_title：Lasers in surgery and medicine

authors： Skobelkin OK,Breckov EI,Bashilov VP,Korepanov VI,Litwin GD,Smoljaninov MV,Malyshev BN,Salyuk VA

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The metabolic flexibility is often impaired in diseases associated with obesity, and many studies are based on the hypothesis that dysfunction in peripheral tissues such as skeletal muscle, liver and adipose tissue represent the etiology of development of metabolic inflexibility. Experimental e...

journal_title：Lasers in surgery and medicine

authors： Sene-Fiorese M,Duarte FO,de Aquino Junior AE,Campos RM,Masquio DC,Tock L,de Oliveira Duarte AC,Dâmaso AR,Parizotto NA,Bagnato VS

更新日期：2015-10-01 00:00:00

abstract：:Progress in the young field of laser recanalization of occluded arteries and applications in cardiovascular disease to which many investigators have contributed is briefly summarized. Specific problems remaining to be solved are set forth. In conclusion, the author makes a cautious prediction of success for the percut...

journal_title：Lasers in surgery and medicine

authors： Choy DS

更新日期：1986-01-01 00:00:00

abstract：:Patients with malignant obstructive airway lesions often present with total or segmental atelectasis of lung. In spite of prompt initiation of palliative external radiation alone, some patients were unable to complete the planned course of radiation therapy. Since May 1983, 17 patients with malignant obstructive endob...

journal_title：Lasers in surgery and medicine

authors： Jain PR,Dedhia HV,Lapp NL,Thompson AB,Frich JC Jr

更新日期：1985-01-01 00:00:00