Abstract:
:Senile macular degeneration is a leading cause of visual loss in the United States, England, and probably many other industrialized countries. The clinical manifestations of this disease include: drusen, atrophy of the retinal pigment epithelium, serous detachment of the retinal pigment epithelium, subretinal neovascularization, and disciform scars. Standardized techniques for defining these manifestations of senile macular degeneration are necessary for epidemiologic study of this disease. Such standardization is facilitated by the use of fundus photographs. If a visual acuity deficit is included in the definition of senile macular degeneration, care must be taken to assure that senile macular degeneration is responsible for the decreased vision. The Framingham Eye Study provides the best senile macular degeneration prevalence data. The rapid increase in prevalence of senile macular degeneration after the fifth decade is demonstrated in this study and is consistent with other studies. In fact, increasing age has the strongest association with senile macular degeneration of any of the risk factors considered to date. Many other possible risk factors have been identified but further investigation is necessary to verify these associations.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Ferris FL 3rddoi
10.1093/oxfordjournals.aje.a113624subject
Has Abstractpub_date
1983-08-01 00:00:00pages
132-51issue
2eissn
0002-9262issn
1476-6256journal_volume
118pub_type
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