Mathematical model of synaptic plasticity: III. Heterosynaptic changes.

Abstract:

:A mathematical model, using differential equations, of heterosynaptic plasticity is proposed. The model is based on physiological studies of invertebrates in which nonspecific conditioning, such as sensitization and heterosynaptic inhibition, starts to be elucidated and behavioral studies of classical and instrumental conditioning, which we postulate to have the same mechanisms as those found in nonspecific conditioning. The model permits us to simulate the following heterosynaptic changes: sensitization, heterosynaptic inhibition, classical and instrumental conditioning--including short- and long-term memory--extinction and recuperation--spontaneously and by stimulation.

journal_name

Neurol Res

journal_title

Neurological research

authors

Lara R,Tapia R,Cervantes F,Moreno A,Trujillo H

doi

10.1080/01616412.1980.11739576

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

137-52

issue

2

eissn

0161-6412

issn

1743-1328

journal_volume

2

pub_type

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